cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Ummy Mardiana Ramdan
Contact Email
joimedlabs.aiptlmi@gmail.com
Phone
+6281223433385
Journal Mail Official
joimedlabs.aiptlmi@gmail.com
Editorial Address
Jl. Arteri JORR Jatiwarna Pondok Melati, Bekasi, Jawa Barat, Indonesia Kode Pos: 17415
Location
Unknown,
Unknown
INDONESIA
Journal of Indonesian Medical Laboratory and Science (JoIMedLabS)
Published by Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medis Indonesia
ISSN : 27750108     EISSN : 27742504     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology
Journal of Indonesian Medical Laboratory and Science (JoIMedLabS) merupakan jurnal AIPTLMI (Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia) yang dapat diakses secara terbuka (open acces) yang berfokus pada pengembangan ilmu pengetahuan Teknologi Laboratorium Medik (TLM) dengan tujuan untuk memperluas pengetahuan, pemikiran dan penelitian di bidang laboratorium kesehatan. Topik yang diangkat meliputi hematologi, kimia klinik, imunoserologi, imunohematologi, sitohitoteknologi, mikrobiologi, parasitologi, dan toksikologi klinik.
Arjuna Subject : Profesi Kesehatan - Teknologi Laboratorium Medis
Articles 8 Documents
 1 
Search results for , issue "Vol 6 No 2: Oktober 2025" : 8 Documents clear
Korelasi Kadar Troponin I dengan Serum Glutamic Oxaloacetic Transaminase (SGOT) dan Low Density Lipoprotein (LDL) Pada Penderita Penyakit Jantung Koroner Di RSUD Haji Provinsi Jawa Timur Amania, Salsabila; Handayati, Anik; Museyaroh
Journal of Indonesian Medical Laboratory and Science Vol 6 No 2: Oktober 2025
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v6i2.279

Abstract

Background: Coronary Heart Disease (CHD) is a condition caused by atherosclerosis, which leads to reduced blood supply to the heart muscle. This condition occurs due to the buildup of plaques resulting form elevated levels of LDL.  Atherosclerosis can trigger myocardial infarction, leading to heart muscle damage and the release of biomarkers such as Troponin I and Serum Glutamic Oxaloacetic Transaminase (SGOT). Objectives: This Study aims to determine the correlation between Troponin I levels and SGOT as well as LDL levels in patients with CHD at Haji General Hospital in East Java Province. Materials and Methods: This study used an analytical observational study with a cross-sectional and purposive sampling. Results: The study results show that the majority of participants were aged 46–65 years (57%) and male (57%). Most patients had high Troponin I levels (70%), normal SGOT levels (63%), and high LDL levels (100%). The correlation analysis using the Spearman test showed a statistically significant correlation between Troponin I and SGOT levels with p value 0.046 and correlation coefficient r= 0.367, but the correlation between Troponin I and LDL levels was not statistically significant with p value 0.330 and correlation coefficient = 0.184. Conclusions:  The study found a correlation between Troponin I and SGOT in patients with CHD and no correlation between Troponin I and LDL in patients with CHD.
Inhibitory Effect of Nutmeg (Myristica fragrans) Leaf Extract on Biofilm Formation by Methicillin-Resistant Staphylococcus aureus (MRSA) Ramadhan, Fahri; Nugroho, Yusuf Eko; Faizal, Imam Agus
Journal of Indonesian Medical Laboratory and Science Vol 6 No 2: Oktober 2025
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v6i2.294

Abstract

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is an opportunistic pathogen with a strong capacity for biofilm formation, which enhances resistance to antibiotics. Although nutmeg (Myristica fragrans) seeds and mace have been extensively studied, research on nutmeg leaves is limited despite their content of flavonoids, tannins, saponins, and triterpenoids with antimicrobial potential. Objective: This study evaluated the antibiofilm activity of nutmeg leaf extract against MRSA biofilm formation in vitro. Materials and Methods: Biofilm assays were conducted using MRSA isolates. The optimal incubation time for biofilm formation was first determined, followed by treatment with nutmeg leaf extract. Results: MRSA formed optimal biofilms at 48 h (OD = 0.101 ± 0.012). Nutmeg leaf extract significantly reduced biofilm formation (OD = 0.083 ± 0.010) compared with the negative control (OD = 0.118 ± 0.009) and the positive control, tetracycline (OD = 0.096 ± 0.011) (p = 0.001). While the reduction was statistically significant, the difference from tetracycline was modest. Conclusion: Nutmeg leaf extract demonstrated significant antibiofilm activity against MRSA in vitro. These findings support its potential as a complementary natural agent for managing biofilm-associated infections, warranting further studies to isolate active compounds and assess synergistic effects with standard antibiotics.
Evaluation of mangosteen peel extract in the kato-katz technique for enhanced visualization of helminth eggs Tanjung, Asbar; Maulidayanti, Sharfina; Br Situmorang, Ing Mayfa
Journal of Indonesian Medical Laboratory and Science Vol 6 No 2: Oktober 2025
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v6i2.299

Abstract

Background: Mangosteen rind (Garcinia mangostana) contains anthocyanins, which have potential as natural dyes. One promising application is as a substitute for malachite green in the Kato-Katz technique, a fecal examination method used to detect helminth eggs such as Ascaris lumbricoides. Objectives: To evaluate the effectiveness of mangosteen peel extract at various concentrations (25%, 50%, 75%, and 100%) as an alternative staining agent in the Kato-Katz method. Materials and Methods: This laboratory-based experimental study utilized fecal samples positive for A. lumbricoides, which were examined using the Kato-Katz method with selophane tape soaked in mangosteen rind extract. Observed parameters included egg count per gram of feces (epg), clarity of egg morphology, and background contrast under the microscope. Results: The 75% concentration yielded the best performance, with optimal background staining, clear egg morphology, and the highest average egg count (853 eggs per gram). Concentrations of 25%, 50%, and 100% showed lower effectiveness. Conclusions: A 75% concentration of mangosteen rind extract is effective as a natural dye substitute for malachite green in the Kato-Katz method, providing good visual contrast and supporting accurate identification of helminth eggs
Correlation between Neutrophil Counts and Salmonella IgM in Typhoid Fever Patients at Emanuel Hospital Banjarnegara Haryanti, Anik; Nugroho, Yusuf Eko; Faizal, Imam Agus
Journal of Indonesian Medical Laboratory and Science Vol 6 No 2: Oktober 2025
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v6i2.311

Abstract

Background: Typhoid fever is an infectious disease caused by Salmonella typhi and remains a significant public health problem in endemic regions. The incidence continues to rise annually, particularly among children. During infection, the immune system responds through both hematological and serological mechanisms, including increased neutrophil counts and the production of Immunoglobulin M (IgM). Neutrophils act as the first line of defense against bacterial invasion, while IgM is the earliest antibody produced during acute infection. Although many studies have independently examined hematological and serological parameters in bacterial infections, limited research has explored the relationship between neutrophil counts and Salmonella IgM in pediatric typhoid fever, especially in endemic areas such as Banjarnegara, Indonesia. Objectives: This study aims to analyze the relationship between neutrophil counts and Salmonella IgM results in pediatric patients with typhoid fever. Materials and Methods: This study is a cross-sectional design utilizing secondary data obtained from the Electronic Medical Records (EMR) and Laboratory Information System (LIS). Results: The results showed that 18 patients (47.4%) had normal or high neutrophil counts, while 2 patients (5.3%) had low neutrophil counts. Regarding Salmonella IgM results, 5 patients (13.2%) tested negative, whereas 33 patients (86.8%) tested positive. Conclusions: The Spearman statistical test yielded a p-value of 0.002 (p < 0.05) with a correlation coefficient of 0.480, indicating a significant relationship between neutrophil counts and Salmonella IgM results at Emanuel Hospital, Banjarnegara. The correlation between neutrophil counts and Salmonella IgM results is considered moderate.
Correlation between Hematocrit and Platelet Counts in Dengue Hemorrhagic Fever Patients: A Study at Emanuel Hospital, Banjarnegara Pancawati, Yulina; Pangesti, Ira; Nugroho, Yusuf Eko
Journal of Indonesian Medical Laboratory and Science Vol 6 No 2: Oktober 2025
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v6i2.312

Abstract

Background: Dengue Hemorrhagic Fever (DHF) is an infectious disease caused by the dengue virus and transmitted by Aedes aegypti mosquitoes. Without prompt management, DHF can lead to severe complications and death. The World Health Organization (WHO) identifies thrombocytopenia and increased hematocrit as key diagnostic parameters for DHF. Objectives: This study aimed to assess the correlation between hematocrit levels and platelet counts in patients with Dengue Hemorrhagic Fever at Emanuel Hospital, Banjarnegara. Materials and Methods: This cross-sectional study used secondary data from the hospital’s Electronic Medical Records (EMR) and Laboratory Information System (LIS). Statistical analysis was performed using Pearson’s correlation test. Results: The analysis showed a significant negative correlation between hematocrit and platelet counts in DHF patients (r = –0.760, p < 0.001). Conclusions: The findings indicate that an increase in hematocrit is associated with a decrease in platelet counts, emphasizing the importance of simultaneous monitoring of both parameters in the clinical management of DHF. This study contributes to local epidemiological data and underscores the potential of these laboratory indicators as practical tools for assessing disease severity.
Association Between HbA1c Level and Renal Function Markers in Patients with Diabetes Mellitus Muhammadiy, Noer Sidqi; Purniawan, Luki Herli; Afthoni, Muhammad Hilmi
Journal of Indonesian Medical Laboratory and Science Vol 6 No 2: Oktober 2025
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v6i2.300

Abstract

Background: Diabetes mellitus (DM) is a major contributor to kidney failure worldwide. Glycated haemoglobin (HbA1c) is widely recognised as a marker for glycemic regulation, yet its association with renal function decline is not fully clarified. Objective: This study investigates the association between HbA1c levels and renal function indicators, namely creatinine, urea, and microalbumin, in individuals with DM. Materials and Methods: A cross-sectional approach was utilised, analysing retrospective data collected from the medical records of DM patients participating in the Prolanis program in Bondowoso Regency during 2024. Correlation tests and linear regression were used to determine the relationship between HbA1c and the selected renal parameters, with a statistical significance threshold of p < 0.05. Results: Most patients exhibited HbA1c levels and renal parameters within normal limits. Nonetheless, a statistically significant positive correlation was identified between elevated HbA1c levels and increased concentrations of creatinine (p = 0.020), urea (p = 0.01), and microalbumin (p = 0.01). Conclusion: Higher HbA1c levels are associated with deteriorating kidney function among DM patients. However, HbA1c should not be solely relied upon as a standalone marker for renal impairment. Further investigations are necessary to elucidate the biological pathways involved and to evaluate the potential of HbA1c control in mitigating kidney disease progression.
The The Effect of Blood Transfusion Frequency on Secretor Status Titer in Saliva and Urine Specimens of Thalassemia Patients Darmantoputro, Feby Wicaksono; Nurhayati, Betty; Hayati, Eem; Marliana, Nina
Journal of Indonesian Medical Laboratory and Science Vol 6 No 2: Oktober 2025
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v6i2.308

Abstract

Background: Thalassemia is a disease caused by a deficiency or loss of synthesis of one or more normal globin chains. In diseases that require blood transfusions, such as Transfusion Dependent Thalassemia (TDT), it is very important to examine the blood type to determine the blood to be transfused. The ABO blood type system antigen or secretor, is found in body fluids in the form of dissolved antigens, including in saliva and urine. Interference can be caused by the frequency of transfusion, which can change the secretor content in the saliva and urine of thalassemia patients, causing false negatives in the examination of secretor status. Objectives: This study aims to determine the effect of transfusion frequency on the titer of secretor status in saliva and urine specimens of Thalassemia patients. Materials and Methods: The type of study is quasi-experimental, Agglutination-Inhibition method. The research sample was 23 Thalassemia major patients. 15 patients are secretor patients, with a frequency of 1x transfusion a month were 7 people (47%), a frequency of 2x transfusion a month were 5 people (33%), and 4x transfusion a month were 3 people (20%). Results: The results of the study on Thalassemia patients obtained from saliva were titers between 1/8 to 1/256. From urine, the results were non-secretors. In contrast to previous studies, which stated that urinary is still detected but four times weaker than saliva. Based on the ANOVA statistical calculation, sig. 0.909 (p>0.05) was obtained. Conclusions: The conclusion is that there is no effect of transfusion frequency on the titer of secretor status in saliva or urine.
Correlation Between Leukocyte Count and Erythrocyte Sedimentation Rate in Pulmonary Tuberculosis Patients at Suai Referral Hospital, Timor Leste Gunawan, Lucia Sincu; Livrança, Expedito José Oliveira; Ismawatie, Emma
Journal of Indonesian Medical Laboratory and Science Vol 6 No 2: Oktober 2025
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v6i2.320

Abstract

Background: Human Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. TB causes serious health problems for about 10 million people each year and is one of the most common causes of death worldwide. The incidence of TB in Indonesia is 354 per 100,000 population, while in Timor-Leste the incidence has stagnated at 498 per 100,000 population. An active TB process may be indicated by an increase in leukocytes and LEDs, whereas an improvement is shown by a decrease in LEDs and normal lecocyte counts. Objectives: This study aimed to determine the correlation between leukocyte count and erythrocyte sedimentation rate (ESR) in pulmonary TB patients at Suai Referral Hospital, Timor-Leste. Materials and Methods: This was an observational analytic study with a cross-sectional approach, conducted from April to June 2023, using medical laboratory records. The study population consisted of pulmonary TB patients who underwent laboratory testing, with a total sampling of 50 patients. Data on leukocyte counts measured using an automated Hematology Analyzer and ESR determined by the Westergren method were tested for normality using the Shapiro-Wilk test, followed by Spearman’s rank correlation test.  Results: The mean leukocyte count was 11.15 ± 5.24 /mm³ and the mean ESR was 63.30 ± 35.71 mm/hour. The correlation test between leukocyte count and ESR showed r = 0.124 (p = 0.392), indicating no significant correlation. Conclusions: There is no significant correlation between leukocyte count and ESR in pulmonary TB patients at Suai Referral Hospital, Timor-Leste.

Page 1 of 1 | Total Record : 8

 1 

Filter by Year

2025 2025


Reset
Filter By Issues
All Issue Vol 6 No 2: Oktober 2025 Vol 6 No 1: April 2025 Vol 5 No 2 (2024): In Progress Vol 5 No 1: April 2024 Vol 4 No 2: Oktober 2023 Vol 4 No 1: April 2023 Vol 3 No 2: Oktober 2022 Vol 3 No 1: April 2022 Vol 2 No 2: Oktober 2021 Vol 2 No 1: April 2021 Vol 1 No 1: Oktober 2020 More Issue