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Yolanda Handayani
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INDONESIA
Respiratory Science
Published by Perhimpunan Dokter Paru Indonesia
ISSN : -     EISSN : 27471306     DOI : https://doi.org/10.36497/respirsci.v1i3.17
Core Subject : Health,
Health Professions Medicine & Pharmacology
Focuses on original article reviews and case reports in pulmonary and critical care medicine Scope: 1. Asthma 2. Chronic Obstructive Pulmonary Disease (COPD) 3. Lung Physiology and Sleep-Related Disorder 4. Lung Infection 5. Thoracic Oncology 6. Interstitial Lung Disease 7. Environmental Lung Disease 8. Tobacco Control 9. Occupational Pulmonary Disease 10. Pulmonary Intervention and Emergency Medicine 11. Respiratory critical care 12. Respiratory immunology and biomolecular
Arjuna Subject : Kedokteran - Kedokteran Paru dan Pernafasan
Articles 8 Documents
 1 
Search results for , issue "Vol. 4 No. 2 (2024): Respiratory Science" : 8 Documents clear
A Rare Case of Completely Healed Pneumomediastinum Due to Asthma Exacerbation in A Young Male Patient Tarigan, Amira Permatasari; Pandia, Pandiaman; Pradana, Andika; Hutabarat, Eva Susanti Debora; Ramadhani, Adini Arifah
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.95

Abstract

Background: The term pneumomediastinum (PNM) refers to the presence of air within the mediastinal cavity. This illness is uncommon but can arise in adolescents with severe asthma attacks. In children aged 5 to 34, the incidence of pneumomediastinum after an acute asthma attack is 1 in 25,000. Men made up the majority of patients (76 percent of all cases). Pneumomediastinum can be diagnosed with the assistance of a chest CT scan. Case: A young man was diagnosed with pneumomediastinum due to an acute asthma attack in this case report. Symptoms of uncontrolled asthma include shortness of breath that worsens with wheezing, chest tightness, and a nonproductive cough. Since the age of 12, the patient in this instance has been receiving salbutamol inhalers. The physical examination revealed polyphonic lung respiration and subcutaneous crepitus in the neck, shoulders, and anterior chest. With adequate management of an asthma episode, pneumomediastinum recovers spontaneously, followed by recurrent symptomatic status, physical examination, and radiography examination. Discussion: Acute asthma exacerbations are one of the factors that can lead to spontaneous pneumomediastinum, in which mediastinal air can permeate the tissue and generate a pneumothorax, and if there is air in the subcutaneous area, it can lead to subcutaneous emphysema. Conclusion: Pneumomediastinum was a rare incidence, pulmonologists examining young adults with acute asthma exacerbations should evaluate for pneumomediastinum. In usual asthma therapy, a chest CT-scan is essential to screen for pneumomediastinum.
Lung Cancer In Former Tuberculosis Patients at Arifin Achmad General Hospital, Riau Province Martarita, Evitrie; Erdayani, Rita; Munir, Sri Melati; Fauzi, Zarfiardy Aksa; Simanjuntak, Arya Marganda
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.97

Abstract

Background: There is ongoing discussion over the connection between lung cancer and pulmonary tuberculosis (TB). Future lung cancer cases in Indonesia, which has the second-highest TB case burden, are a cause for concern. The purpose of this study is to ascertain the connection between TB and LC at Arifin Achmad General Hospital in the province of Riau. Method: From 2015 to 2018, we looked back on lung cancer patients at Arifin Achmad General Hospital in Riau Province who had received pulmonary tuberculosis and anti-tuberculosis treatment (ATT). Results: From 203 patients, 24 patients (11.8%) had histories of TB. The patients' ages were from 41 years to 60 years. The most prevalent pathological findings were adenocarcinoma in 13 patients (54.0%). The most common cancer stage was advanced stage IIIB in 7 patients (29.2%) Conclusion: The cases of TB infections were apparent in lung cancer patients, approximately around 11% of lung cancer cases. Therefore, it is necessary to assess the history of TB in lung cancer patients.
Diagnosis and Management for Pulmonary Tuberculoma Syahruddin, Elisna; Burhan, Erlina; Saputra, Tetra Arya
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.107

Abstract

Pulmonary tuberculoma, prevalent particularly in tuberculosis (TB)-endemic regions, often appears as a solitary nodule of less than 30 mm, or a tumor of more than 30 mm on radiological examinations. It may also present with a combination of abnormalities, such as multiple nodules with infiltration or pleuritis. Benign solitary pulmonary nodules represent up to 25% of all resected solitary pulmonary nodules, with approximately 5-24% of these identified as pulmonary tuberculoma post-surgery. This condition is prevalent particularly in TB-endemic regions, and must be considered while determining the diagnosis, especially for patients at high risk for lung cancer. Modalities for diagnosing pulmonary tuberculoma include chest radiography, USG, CT scan, PET scan and bronchoscopy with transbronchial biopsy. The treatments for pulmonary tuberculoma are anti-TB drugs and surgery. Pulmonary tuberculoma responds poorly to anti-TB drugs and requires long-term treatment. Surgery is performed when the diameter of tuberculoma still increases after adequate anti-TB treatment.
Characteristics of Lung Cancer Patients with Brain Metastases based on Baseline Head Computerized Tomography (CT)-scan in Arifin Achmad Hospital October 2022 - June 2023 Sari, Rezki Permata; Fauzi, Zarfiardy Aksa; Simanjuntak, Arya Marganda
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.108

Abstract

Background: The majority of lung cancer cases are often discovered at a late stage because it frequently develops without symptoms in the early stages. Many lung cancer deaths are caused by metastases to other organs. The purpose of this study was to examine the features of lung cancer patients with brain metastases using baseline CT scan data. Method: Between October 2022 and June 2023, a cross-sectional study was conducted at the Arifin Achmad Hospital in Pekanbaru on all newly diagnosed lung cancer patients with brain metastases who also met the inclusion and exclusion criteria. Results: Eight subjects of lung cancer with brain metastasis were found from 49 patients. All subjects were male with age mostly in between 40 and 60 years. Three subjects (37.5%) were Squamous Cell Carcinoma (SCC), four subject (50%) were adenocarcinoma and 1 (12.5%) were SCLC. Conclusion: This study discovered that 16.3% of patients who met the inclusion criteria had lung cancer with brain metastases. Further research should be done on a cohort study and a preventive strategy for lung cancer with brain metastases.
The Relationship Between SpO2/FiO2 Ratio to Community Acquired Pneumonia Patient Outcomes at Kolonel Abunjani Bangko General Hospital Lindra, Derallah A; Sari, Oktriga A.
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.118

Abstract

Background: Acute lower respiratory tract infection causes high morbidity and mortality, which can be found in the form of pneumonia. Community acquired pneumonia (CAP) severe pneumonia can lead to acute respiratory distress. To diagnose acute respiratory disorders, namely Acute Lung Injury (ALI) and Acute Respiratory Stress Syndrome (ARDS), the ratio PaO2/FiO2 is used. This requires invasive action by taking an arterial blood sample, which is expensive and not available in all health facilities. An alternative is pulse oximetry, which measures the SpO2/FiO2 ratio and is available in health facilities. It is inexpensive and non-invasive. This study aims to determine the relationship between SpO2 and FiO2 with the outcome of community pneumonia patients at Kolonel Abunjani Bangko Hospital. Method: The study design was a retrospective descriptive cross-sectional design. The research subjects were a total sampling of medical record data from inpatients with community acquired pneumonia for the period January-December 2022. The study variables included gender, age, SpO2/FiO2 ratio, and outcomes of pneumonia patients. Univariate and bivariate statistical tests were used to analyze the data. Results: In this study, there were 43 subjects who met the inclusion criteria. The distribution of inpatient community acquired pneumonia patients, especially in the gender was mostly male (67.4%), the highest age was 56–65 years and >65 years (both 37.2%), the median SpO2 was 94% (36-99%), the median SpO2/FiO2 ratio was 447 (171-471%), the highest outcomes were alive patients (36 patients). The ratio of SpO2/FiO2 >316 was the majority (33 patients). Based on the relationship between the SpO2/FiO2 ratio and the outcome of CAP with alive outcome was a SpO2/FiO2 ratio >236 was more numerous than SpO2/FiO2 ratio <236 with value of P=0.0005. Conclusion: There is a significant relationship between the SpO2/FiO2 ratio and the outcome of community acquired pneumonia patients at Kolonel Abundjani Hospital Bangko.
Bronchoscopic Balloon Dilatation for Tuberculosis-related Bronchial Stenosis: A Rare Case Wahyuni, Titis Dewi; Alatas, Mohamad Fahmi; Widysanto, Allen; Siahaan, Sylvia Sagita; Muljadi, Rusli; Carolline, Chaifung
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.125

Abstract

Background: Bronchial stenosis is known as a complication of endobronchial tuberculosis (EBTB). The incidence of stenosis affects quality of life. A minimally invasive therapeutic strategy, bronchoscopic balloon dilatation (BBD), can be chosen to manage the disease. Case: A 29-year-old woman suffered from bronchial stenosis, which appeared after completing treatment for tuberculosis (TB). She was diagnosed with TB around the middle of her pregnancy. She received anti-tuberculosis treatment for six months. Two years later, she complained of a persistent cough for two weeks prior to hospitalization. A complete stenosis of the left main bronchus with atelectatic on the left lung was seen on a chest CT scan. The result was confirmed with a bronchoscopy procedure. There were no mycobacteria or other suspicious organisms found in bronchial washings. Bronchoscopic balloon dilatation action was successful. Discussion: Endobronchial tuberculosis is a tuberculous infection that affects the tracheobronchial tree. It can be treated with minimally invasive procedures like bronchoscopy or surgical interventions. If the stenosis is mild or moderate, several procedures such as balloon dilatation, stents, laser photoresection, argon plasma coagulation, and cryotherapy are often performed. Bronchoscopy balloon dilatation nowadays has become a more preferred treatment option for tracheal and bronchial stenosis because  it may be areliable and effective method.    Conclusion: The BDD procedure in this patient showed good results. This procedure is fast, easy, safe, minimally invasive, and the symptoms resolve quickly. It can be concluded that BBD is a safe and effective therapy for TB-related bronchial stenosis, but the long-term effects of the procedure remain to be monitored.
Relationship Between D-Dimer, Albumin Levels, and Outcome of COVID-19 Patients at Dr. M. Djamil General Hospital, Padang Wahyudin, Hendris Utama Citra; Khairsyaf, Oea; Russilawati, Russilawati
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.128

Abstract

Background: Several studies have found an increase in D-dimer levels in patients who died from a severe clinical condition. COVID-19 exhibits multi-organ dysfunction through several markers, including decreased albumin levels. There were some studies that were interested in understanding how D-dimer and albumin levels relate to the outcomes of COVID-19 patients. The aim of this study was to investigate the relationship between D-dimer, albumin levels, and patient outcomes. Method: This was a cross-sectional study of all COVID-19 patients treated at Dr. M. Djamil General Hospital, Padang, from January 1st, 2021 to December 31st, 2021. Results: The majority of patients (40.71%) were in the group of 18 and 49 years old; more than half of the subjects (56.16%) were female; and obesity was the most common comorbidity (40.9%). The majority of the subjects (42.79%) had moderate clinical COVID-19. Higher D-dimer levels had a statistically significant independent relationship with unfavorable outcomes (P=0.0001). Lower albumin levels had a statistically significant independent relationship with unfavorable outcomes (P=0.0001). Higher D-dimer and lower albumin each contributed 12.6% to patient outcome. Increasing D-dimer levels per 1 ng/mL would increase the probability of an unfavorable outcome by 0.120 times, and on the other hand, increasing albumin levels per 1 g/dL would increase the probability of survival by 2.143 times. Conclusion: Higher D-dimer levels independently had a relationship with an unfavorable outcome. Higher albumin levels were independently related to a favorable outcome.
Evaluation of Mortality Risk Factors of COVID-19 in Jakarta Tertiary Hospital During Peak of Second Wave and Predictive Utility of Community RT-PCR Low CT Values Putra, Andika Chandra; Burhan, Erlina; Aufa, Akhdan; Bur, Rika; Pangestu, Hendri; Bahri, Syukrini; Souvriyanti, Elsye; Muchtiar, Mulyadi; Erlina, Andi; Aditama, Tjandra Yoga; Yuliwulandari, Rika; Kusuma, Indra; Suciati, Yulia; Rifqatussaadah, Rifqatussaadah; Jalal, Fasli; Gusnanto, Arief; Utomo, Ahmad Rusdan H
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.133

Abstract

Background: The Delta variant of SARS-CoV-2 led to a surge in COVID-19 cases in Indonesia. This study aimed to assess the demographic profile and mortality rates of hospitalized COVID-19 patients in YARSI referral hospital, Jakarta, comparing pre-Delta and Delta wave periods. The study also investigated whether low CT values in RT-PCR tests indicated heightened viral transmission before the Delta wave surge. Method: A retrospective analysis was conducted on 1,457 COVID-19 patients hospitalized at YARSI (January-August 2021) and 25,279 RT-PCR test results from walk-in patients (April-August 17, 2021). Differences were evaluated using Chi-square or Fisher’s Exact Tests while binary logistic regression was used to assess mortality risk factors. Results: There were increased proportions of pregnant women, patients aged 20-29 and those with coronary artery disease during the Delta wave. This period also showed a significant increase in mortality rates, with the highest seen in patients >60 years old or those with multiple comorbidities. Notably, most of the deceased patients (131 of 139) were unvaccinated. Analysis of RT-PCR data showed rising percentages of positive results with low CT values (below 21 or 15) from April to June. Conclusion: The Delta wave saw a higher risk of hospitalization among young individuals and pregnant women, despite their low mortality risk. The unvaccinated and those with multiple comorbidities faced higher mortality risks. Increases in RT-PCR positivity with low CT values preceded the July COVID-19 case surge.

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