cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Muhammad Taupik
Contact Email
muhtaupik@ung.ac.id
Phone
+6281547458537
Journal Mail Official
redaksiijpe@ung.ac.id
Editorial Address
Unit Redaksi IJPE, Gedung FOK, Jurusan Farmasi, Fakultas Olahraga dan Kesehatan Universitas Negeri Gorontalo. Jln. Jenderal Sudirman No. 06, Kota Tengah, Kota Gorontalo, 96128, Gorontalo, Indonesia. Surat Elektronik : redaksiijpe@ung.ac.id Telf/Fax : 0435-821698 / 0435-821698 Phone (Whatshaap) : +6281547458537
Location
Kota gorontalo,
Gorontalo
INDONESIA
Indonesian Journal of Pharmaceutical Education
Published by Universitas Negeri Gorontalo
ISSN : -     EISSN : 27753670     DOI : https://dx.doi.org/10.37311/ijpe
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology Medicine & Pharmacology
ndonesian Journal of Pharmaceutical Education (IJPE) adalah junal resmi yang diterbitkan oleh Jurusan Farmasi Universitas Negeri Gorontalo yang bekerja sama dengan IAI (Ikatan Apoteker Indonesia) Provinsi Gorontalo. Artikel pada jurnal ini dapat diakses dan unduh secara online oleh publik (open access journal). Jurnal ini adalah jurnal peer-review nasional, yang terbit tiga kali dalam setahun tentang topik-topik keunggulan hasil penelitian di bidang pelayanan dan praktek kefarmasian, pengobatan masyarakat, teknologi kefarmasian serta disiplin ilmu kesehatan yang terkait erat. Jurnal ini menerima naskah berbahasa Indonesia dan Inggris. Berikut merupakan area-area yang difokuskan oleh jurnal ini Farmasi Klinis Farmasi Komunitas Farmasetika Kimia Farmasi Farmakognosi Fitokimia Naskah yang terpilih untuk dipublikasikan di Indonesian Journal of Pharmaceutical Education akan dikirim ke reviewer yang pakar dibidangnya, yang tidak berafiliasi dengan lembaga yang sama dengan penulis dan dipilih berdasarkan pertimbangan tim editor. Naskah yang diterima untuk publikasi adalah salinan yang diedit untuk tata bahasa, tanda baca, gaya cetak, dan format. Seluruh proses pengajuan naskah hingga keputusan akhir untuk penerbitan dilakukan secara online.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 8 Documents
 1 
Search results for , issue "Vol 1, No 3 (2021): September-Desember 2021" : 8 Documents clear
SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIOKSIDAN JANTUNG PISANG GOROHO (Musa acuminafe L.) DENGAN METODE 1,1-DIPHENYL-2-PICRYLHIDRAZYL (DPPH) Dr. Widysusanti abdulkadir S.Si.,M.Si.,Apt; Dr. Apt. Hamsidar Hasan S.Si.,M.Si; ading ading alamsyah
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11371

Abstract

Goroho banana (Musa acuminafe L.) has its own characteristics and is one of the local varieties of banana that is not widely known to people outside North Sulawesi. In addition, it is commonly used as an antioxidant. Antioxidants are substances that can improve the function of layers of blood vessels, inhibit blood platelet aggregation where it can stimulate the production of Nitric Oxide, which causes the relaxation of blood vessels and can reduce the sensitivity of Low-Density Lipoprotein (LDL) to the effects of free radicals. Therefore, this research aims to determine the chemical content and antioxidant activity of Goroho Banana (Musa acuminafe L.) by using DPPH (1,1-diphenyl-2-picrylhydrazyl) method. Besides, the extraction of samples is carried out by employing extraction graded with n-hexane, chloroform, ethyl acetate, and ethanol solvents. Findings reveal that Goroho banana (Musa acuminafe L.) peel extract contains Alkaloid and Flavonoid compounds. Meanwhile, the value of antioxidant activity indicates that the IC50 value for n-hexane, chloroform, ethyl acetate, and ethanol extracts are 6.38, 5.48, 5.11, 4.19 ug/ml, respectively. In conclusion, the IC50 value discloses that the antioxidant activity is in a strong category.
PENGARUH KONSENTRASI HYDROXYPROPYL METHYLCELLULOSE SEBAGAI BAHAN PENGIKAT PADA SEDIAAN TABLET EKSTRAK RIMPANG JAHE MERAH (zingiber officinale Var. Rubrum.) Nur AIn Thomas; Widy Susanti Abdulkadir; Muhammad Taupik; Nur Oktaviana
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11667

Abstract

Lozenges are solid preparations made from aromatic and sweet taste that can dissolve slowly in the mouth, which are intended to treat infections in the mouth and throat. Hydroxypropyl Methylcellulose (HPMC) is a binder that can be used in lozenges.This study attempted to examine the effect of the concentration of HPMC as a binder in the tablet preparation of red ginger rhizome extract (Zingiber officinale Var Rubrum) by wet granulation method. This study was a laboratory experimental study by comparing the three concentrations of HPMC binder used in each formula i.e., FI (4%), FII (5%), FIII (6%).The resulting tablets were tested for physical properties including organoleptic tests, weight uniformity, tablet hardness, tablet friability and hedonic tests. Based on the results of the study, it was shown that with an increase in the concentration of the HPMC binder, the physical quality of the resulting tablet also increased. The higher the concentration of HPMC used, the better the uniformity of weight and the high level of tablet hardness. However, tablet friability will decrease. The results showed that the concentrations of 4%, 5%, and 6% had an effect on the tablet physical properties whichwas fragility. Further, formula II with a concentration of 5% had better tablet physical quality and was preferred by respondentsbased on hedonic tests.
STANDARISASI DAN KADAR FLAVONOID TOTAL EKSTRAK ETIL ASETAT KULIT BATANG NANGKA (Artocapus heterophylus L) Niluh Sri Purnama; Hamsidar Hasan; Mahdalena Sy Pakaya
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11140

Abstract

Nangka (Artocarpus heterophylla L) adalah tumbuhan yang banyak terdapat di Indonesia. Hampir seluruh bagian pohon nangka dapat dimanfaatkan sebagai obat herbal dimana senyawa flavonoid terprenilasi merupakan metabolit sekunder utama yang terdapat dalam genus Artocarpus. Di Indonesia penggunaan obat herbal masih bersifat tidak terukur baik dari segi takaran, maupun proses penyiapannya. Sehingga perlu dilakukan standarisasi hal ini dilakukan untuk menjaga konsistensi serta keseragaman dari bahan obat herbal. Penelitian ini bertujuan untuk menentukan parameter standarisasi spesifik dan non spesifik serta menentukan kadar flavonoid total ekstrak etil asetat kulit batang nangka. Metode ekstraksi yang digunakan adalah maserasi bertingkat menggunakan pelarut n-heksan, etil asetat dan metanol. Hasil penelitian mengenai parameter organoleptik dari ekstrak etil asetat kulit batang nangka yaitu berwarna merah kehitaman, bau khas, rasa pahit sepat dengan tekstur kental. Simplisia kulit batang nangka memiliki tiga lapisan warna yaitu abu-abu kehijauan dengan bercak putih, lapisan orange dan lapisan coklat muda dengan permukaan tidak rata dan tebal kulit batang kurang lebih 1 cm, serbuk simplisia kulit batang nangka memiliki fragmen kristal oksalat bentuk prisma, serabut, jaringan gabus hablur, dan  parenkim dengan amilum. Ekstrak etil asetat mengandung senyawa flavonoid, dan alkaloid. Dan parameter non spesifik ekstrak etil asetat kulit batang nangka yaitu kadar air 16,97%, susut pengeringan 10,48%, kadar abu 9,78%, kadar abu tidak larut asam 1,58% dan bobot jenis 0,912. Dengan kadar flavonoid ekstrak etil asetat adalah 28,1025 µg/mL.
EFEK AFRODISIAKA EKSTRAK KULIT BATANG SANREGO (Lunasia amara Blanco) TERHADAP MENCIT JANTAN (Mus musculus) Hamsidar Hasan; Juliyanty Akuba; Beatrice Nathania Wilkinson
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11375

Abstract

Sanrego (Lunasia amara Blanco) merupakan salah satu jenis tanaman yang digunakan sebagai afrodisiaka oleh masyarakat Sulawesi Selatan. Penelitian ini bertujuan untuk mengetahui efek afrodisiaka dari ekstrak n-heksan, kloroform, etil asetat dan metanol kulit batang Sanrego (Lunasia amara Blanco) serta mengetahui dosis yang diperlukan untuk memberikan efek afrodisiaka pada mencit jantan. Metode ekstraksi yang digunakan adalah maserasi bertingkat menggunakan pelarut dengan kepolaran meningkat yaitu n-heksan, kloroform, etil asetat dan metanol. Dilakukan pengamatan pada mencit serta menghitung jumlah Introduksi (Pendekatan), Climbing(Penunggangan) dan Coitus(Senggama) selama 5 hari. Data dianalisis menggunakan SPSS One way Anova. Hasil penelitian skrining fitokimia menunjukkan adanya senyawa steroid yang terkandung dalam ekstrak N-Heksan, kloroform, etil asetat dan metanol, terdapat senyawa flavonoid dalam ekstrak kloroform, etil asetat, metanol. Terdapat senyawa tanin dalam ekstrak etil asetat dan metanol dan terdapat senyawa alkaloid dalam ekstrak metanol. Ekstrak yang memberikan efek afrodisiaka yaitu ekstrak metanol dan dosis yang diperlukan untuk memberikan efek afrodisiaka pada mencit yaitu 35mg/kgBB dan 70 mg/kgBB. Hasil analisis data One way Anova (p kurang dari 0,01) dengan tingkat kepercayaan 99%
POLA PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN HIPERTENSI Teti Sutriyati Tutoli; Nur Rasdiana; faradilasandi tahala
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11083

Abstract

Hypertension is an increase in systolic blood pressure of at least 140 mmHg or a diastolic pressure of at least 90 mmHg. This study aimed to determine the use of drugs in outpatient hypertension patients at the PuskesmasTilamuta. The design employed in this study wa a non-analytic descriptive analysis method by calculating the percentage of the amount of 3T, namely the right indication, the right drug, and the right dose in a non-experimental manner with a cross sectional design (cross-sectional) and retrospective data collection. Data were collected through mecical records of outpatient hypertension patiens in the area from January 2020 to Desember 2020. Then, the research subjects who met the inclusion criteria were 92 patients. The results showed that the calcium channel bloker (Amlodipine) class antihypertensives were mostly used at 53%. Based on the results of the study, it was found that some patients were not given anthypertensive drugs with inappropriate  drug percentage (23%), incorrect indications (23%), inapporiate dosage (23%). Therefore, it is concluded that some patients do not comply with the accuracy of the indication, drugs, and the accuracy of dosage, so it is necessary to monitor the administration of antihypertensive drugs.
Formulasi, Karakterisasi, Dan Evaluasi Drops Liquid Self Nano-Emulsifying Drug Delivery System (SNEDDS) Astaxanthin Robert Tungadi; Nur Ain Thomas; Wanda Gita Van Gobel
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11400

Abstract

SNEDDS are isotropic mixtures of oil, surfactant, and cosurfactant that produce spontaneous nanoemulsions once they make contact with gastric juices in order to increase the solubility of active pharmaceutical ingredients. One of the active pharmaceutical ingredients with low solubility is Astaxanthin. This research aims at formulating, characterizing, and evaluating SNEDDS containing Astaxanthin in the form of droplets. This research is a laboratory experiment. SNEDDS containing Astaxanthin droplets are made in 3 formulas using the ratio of surfactants and co-surfactants which are characterized to produce F1, F2, and F3 transmittance values of 91%, 90%, and 95%, respectively. Furthermore, the F1 particle size value of 183.75 nm obtains a PDI value of 0.272, the F2 particle sizevalue of 195.25 nm obtains a PDI value of 0.341, and the F3 particle size value of 105.75 nm obtains a PDI value of 0.392. This signifies that the absorption efficiency of F1, F2, and F3 are 94.62%, 94.35%, and 95.57%, respectively. The evaluation reveals the insignificant changes in the emulsion viscosities of SNEDDS containing Astaxanthin liquid drop after having received a stability test for 28 days using Paired T. Test data analysis (p0.05). The research findings show that the F3 of 72% surfactant and 18% co-surfactant concentrations are the best formula in producing SNEDDS. It concludes thar the higher the surfactant concentration produced, the greater the ability to, oil droplets resulting in obtaining small partidles and high absorption efficiency.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN KECUBUNG (Datura metel L.) TERHADAP BAKTERI Streptococcus pneumonia DAN Klabsiella pneumonia A. Mu’thi Andy Suryadi; Moh Adam Mustapa; Faramita Hiola; Sintiya Basiru
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11776

Abstract

Infectious disease is a disease caused by microbes, including bacteria. One of the microorganisms that often causes infectious disease is Streptococcus pneumoniae and Klabsiella pneumoniae. Based on empirical data, plant that has antimicrobial potential is amethyst leaves (Datura metel L.). This study aims to know the antibacterial activity and concertration of amethyst leaves (Datura metel L.) against Streptococcus pneumoniae and Klabsiella pneumonia. This is an experimental study which includes antibacterial activity test, MIC (Minimum Inhibitor Concertration) test, MFC (Minimum Fungicidal Concertration) test, and bacterial potency test. The finding shows that the antibacterial activity test of amethyst leaves (Datura metel L.) methanol extract is able to inhibit bacterial growth of Streptococcus pneumonia at a minimum inhibitor concertration of 15% and an optimum concertration of 50% with an average of 16.33 mm and 19.30 mm. Meanwhile, for Klabsiella pneumoniae, the minimum inhibitor concertration is 20% and the optimum concertration is 50%, with an average of 13.82 mm and 17.73 mm. this is based on the results of One Way Anova data (a 0.01) with a 99% confidance level. 
Analisis Biaya dan Nilai Utilitas pada Pasien Hemodialisis yang Diberikan Terapi Erythropoiesis di Rumah Sakit Madania Madania; Tety Sutriyati Tuloli; Nur Rasdianah; Juliyanty Akuba
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11360

Abstract

Chronic kidney failure is a condition where there is a gradual decline in kidney function. Chronic kidney disease is often followed by complications of anemia. The use of erythropoietin therapy in chronic renal failure patients undergoing hemodialysis requires no small amount of money. This affects the quality of life (utility). The purpose of this study is to measure costs and utility values using the EQ-5D-5L (EuroQol-Five Dimensions) instrument, VAS (Visual Analog Scale), and costs based on the patient's perspective at Prof.Aloei Saboe Hospital. This study is a prospective cross-sectional approach. Data was collected using the EQ-5D-5L and EQ-VAS questionnaires. The subjects of the study were hemodialysis patients as many as 45 met the inclusion criteria. The results showed that the most widely used Erythropoietin therapy was single Hemapo. The results of the calculation of the estimated cost of each hemodialysis patient from the perspective of a patient for one month of therapy are Rp. 7,112,000. The average expenditure of patient transportation costs is Rp. 50,111. The average cost of food for the patient is Rp. 25,000.Utility value based on average Indonesian set value 0.673 (sufficiently feeling well)and VAS score 71.4 (health status is quite healthy).

Page 1 of 1 | Total Record : 8

 1 

Filter by Year

2021 2021


Reset
Filter By Issues
All Issue Vol 5, No 3 (2025): September–December 2025 Vol 5, No 2 (2025): May–August 2025 Vol 5, No 1 (2025): January–April 2025 Vol 4, No 3 (2024): September-Desember 2024 Vol 3, No 3 (2023): September-Desember 2023 Vol 3, No 2 (2023): Mei-Agustus 2023 Vol 3, No 1 (2023): Januari-April 2023 Vol 2, No 3 (2022): September-Desember 2022 Vol 2, No 2 (2022): Mei-Agustus 2022 Vol 2, No 1 (2022): Januari-April 2022 Vol 2, No 1 (2022): Januari-April 2022 (in press) Vol 1, No 3 (2021): September-Desember 2021 Vol 1, No 3 (2021): September 2021 Vol 1, No 2 (2021): Mei-Agustus 2021 Vol 1, No 1 (2021): Januari-April 2021 More Issue