cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Muhammad Taupik
Contact Email
muhtaupik@ung.ac.id
Phone
+6281547458537
Journal Mail Official
redaksiijpe@ung.ac.id
Editorial Address
Unit Redaksi IJPE, Gedung FOK, Jurusan Farmasi, Fakultas Olahraga dan Kesehatan Universitas Negeri Gorontalo. Jln. Jenderal Sudirman No. 06, Kota Tengah, Kota Gorontalo, 96128, Gorontalo, Indonesia. Surat Elektronik : redaksiijpe@ung.ac.id Telf/Fax : 0435-821698 / 0435-821698 Phone (Whatshaap) : +6281547458537
Location
Kota gorontalo,
Gorontalo
INDONESIA
Indonesian Journal of Pharmaceutical Education
Published by Universitas Negeri Gorontalo
ISSN : -     EISSN : 27753670     DOI : https://dx.doi.org/10.37311/ijpe
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology Medicine & Pharmacology
ndonesian Journal of Pharmaceutical Education (IJPE) adalah junal resmi yang diterbitkan oleh Jurusan Farmasi Universitas Negeri Gorontalo yang bekerja sama dengan IAI (Ikatan Apoteker Indonesia) Provinsi Gorontalo. Artikel pada jurnal ini dapat diakses dan unduh secara online oleh publik (open access journal). Jurnal ini adalah jurnal peer-review nasional, yang terbit tiga kali dalam setahun tentang topik-topik keunggulan hasil penelitian di bidang pelayanan dan praktek kefarmasian, pengobatan masyarakat, teknologi kefarmasian serta disiplin ilmu kesehatan yang terkait erat. Jurnal ini menerima naskah berbahasa Indonesia dan Inggris. Berikut merupakan area-area yang difokuskan oleh jurnal ini Farmasi Klinis Farmasi Komunitas Farmasetika Kimia Farmasi Farmakognosi Fitokimia Naskah yang terpilih untuk dipublikasikan di Indonesian Journal of Pharmaceutical Education akan dikirim ke reviewer yang pakar dibidangnya, yang tidak berafiliasi dengan lembaga yang sama dengan penulis dan dipilih berdasarkan pertimbangan tim editor. Naskah yang diterima untuk publikasi adalah salinan yang diedit untuk tata bahasa, tanda baca, gaya cetak, dan format. Seluruh proses pengajuan naskah hingga keputusan akhir untuk penerbitan dilakukan secara online.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 152 Documents
 12   13   14   15   16 
Formulation and Physicochemical Evaluation of Telang Flower (Clitoria ternatea) Extract Lotion as a Skin Moisturizer Nuraini, April; Naila, Fina
Indonesian Journal of Pharmaceutical Education Vol 5, No 3 (2025): September–December 2025
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v5i3.32627

Abstract

Dry skin is a common dermatological condition that can adversely affect both comfort and appearance. Natural moisturisers, such as butterfly pea flower (Clitoria ternatea), offer a safe alternative due to their flavonoid and anthocyanin content, which provide antioxidant properties and enhance skin hydration. This study aimed to formulate and evaluate hand and body lotion containing C. ternatea extract and to assess the effect of varying extract concentrations on its physicochemical properties and moisturising efficacy. An experimental study with a quantitative descriptive design was conducted. Three formulations containing 1%, 3%, and 5% extract were prepared using the maceration method with 96% ethanol. Physicochemical evaluations included organoleptic, homogeneity, pH, spreadability, adhesion, and skin moisture tests, with statistical analysis using one-way ANOVA. All formulations met the quality requirements for topical preparations. Significant differences (p 0.05, ANOVA) were observed in pH, adhesion, and moisture, while spreadability showed no significant differences among formulations. The results demonstrate that C. ternatea extract can be successfully incorporated into lotion formulations with effective moisturising properties. Further research should include long-term stability testing, in vivo efficacy and safety assessments, and consumer acceptability evaluations.
UV–Vis Quantification of β-Carotene in Spinach under Raw and Boiled Conditions Damanik, Sumayyah; Sartika Daulay, Anny; Ridwanto, Ridwanto; Harun, Fathur Rahman
Indonesian Journal of Pharmaceutical Education Vol 5, No 3 (2025): September–December 2025
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v5i3.32374

Abstract

β-Carotene is a provitamin A with strong antioxidant activity but is unstable to heat and oxidation. This study aimed to determine the β-carotene content of green spinach (Amaranthus viridis L.) and red spinach (Amaranthus tricolor L.) under fresh and boiled conditions using UV–Vis spectrophotometry. The assay was performed at 451 nm after maceration extraction with n-hexane:acetone:ethanol (2:1:1, v/v). Calibration in the range of 4–10 μg/mL showed excellent linearity (y = 0.064x – 0.003, r = 0.999). The results demonstrated that red spinach contained substantially higher β-carotene than green spinach. Boiling slightly increased the content in green spinach (17.16 → 18.76 ± 0.21 mg/g), while it caused a small decrease in red spinach (50.23 → 47.76 mg/g). These findings suggest that boiling has different effects depending on the spinach type, possibly due to a balance between heat-induced degradation and enhanced release from softened plant tissues. In conclusion, red spinach is a richer dietary source of β-carotene, but thermal processing reduces its stability. The validated UV–Vis spectrophotometric method is suitable for routine determination of β-carotene in leafy vegetables.
Attitude and Social Support Associated with Weekly Iron-Folic Acid Adherence Among Adolescent Girls in Badung, Bali, Indonesia Gusti Ayu Putu Laksmi Puspa Sari; Ni Putu Udayana Antari; I Gusti Agung Ari Kusuma Yana; Yosi Irawati Wibowo; Adji Prayitno Setiadi; Ni Nyoman Yudianti Mendra
Indonesian Journal of Pharmaceutical Education Vol 6, No 1 (2026): January–April 2026
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v6i1.37340

Abstract

Anemia among adolescent girls in Indonesia remains a significant public health problem. Attitude and social support may influence the success of anemia prevention through adherence to weekly iron–folic acid (IFA) supplementation. This cross-sectional study analyzed the association between attitude, family support, peer support, school support, and adherence to weekly IFA supplementation among adolescent girls in one junior high school in Badung, Bali, Indonesia. All eligible adolescent girls were included in the study (n = 141), and data were collected using a structured questionnaire. Univariate analysis was used to describe respondent characteristics, while bivariate analysis using the Chi-square test and Fisher’s exact test was performed to examine associations between variables. A total of 83.0% of respondents were adherent to weekly IFA supplementation. Among all respondents, 45.4% had a positive attitude, 13.5% had family support, 72.3% had peer support, and 95.7% had school support. School support was significantly associated with adherence to weekly IFA supplementation (p = 0.001), and adolescent girls who received school support had higher odds of adherence than those who did not (OR = 30.5; 95% CI: 3.4–276.2). These findings indicate that school support plays an important role in improving adherence to weekly IFA supplementation among adolescent girls. Strengthening the role of educational institutions through structured supervision and health education may enhance adherence and support anemia prevention programs in this population.
Optimization and Characterization of Syzygium cumini Leaves Extract Alginate–Kappa-Carrageenan Microspheres Reski Mulia; Meiliza Ekayanti; Mochamad Fajar Deliaz
Indonesian Journal of Pharmaceutical Education Vol 6, No 1 (2026): January–April 2026
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v6i1.37326

Abstract

Syzygium cumini leaves contain flavonoids and other phytochemicals with promising pharmaceutical potential; however, the direct use of the extract is limited by poor stability and low bioavailability. This study aimed to formulate and characterize alginate–kappa-carrageenan microspheres containing the ethanol extract of S. cumini leaves prepared by ionic gelation using CaCl₂ as a crosslinking agent. The extract was obtained by maceration with 96% ethanol, yielding 19.6%. Phytochemical screening confirmed the presence of alkaloids, flavonoids, saponins, tannins, and polyphenols. Three formulations containing 0.2%, 0.3%, and 0.4% extract were prepared and evaluated for organoleptic properties, microsphere yield, morphology, particle size, moisture content, and entrapment efficiency (EE). All formulations produced fine light-green powders with a characteristic herbal odor. Microsphere yield ranged from 92.45 ± 0.52% to 93.96 ± 0.52% and differed significantly among formulations (p 0.05). Particle size ranged from 3.16 ± 0.25 to 3.30 ± 0.00 µm, with polydispersity index values of 0.55–0.58, indicating moderately polydisperse systems. Moisture content remained low, ranging from 3.43 ± 0.86% to 3.81 ± 0.45%. EE increased with extract concentration, and F3 showed the highest value (69.91 ± 1.18%), which differed significantly from the other formulations (p 0.05). These findings indicate that alginate–kappa-carrageenan microspheres are a promising carrier system for S. cumini leaf extract and may improve flavonoid protection. Further studies on release behavior and storage stability are needed to confirm their performance.
Liquid Soap with Piper betle L. Ethanolic Extract: Physical Stability over 28 Days at Different Extract Levels Gloria Maria Isabella Manek; Eni Kartika Sari; Mega Karina Putri
Indonesian Journal of Pharmaceutical Education Vol 6, No 1 (2026): January–April 2026
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v6i1.34060

Abstract

Liquid soap is widely used as a cleansing product because it is hygienic, practical, and easy to apply, while incorporation of plant-based bioactives is increasingly explored to enrich functional attributes of personal-care formulations. Ethanolic extract of betel leaf (Piper betle L.) contains multiple secondary metabolites, including flavonoids, alkaloids, steroids, saponins, tannins, and essential oils, which may contribute to formulation performance. This study evaluated the effect of P. betle ethanolic extract level (20%, 25%, and 30%; corresponding to 10.0, 12.5, and 15.0 g per 50 mL batch) on the physical stability of liquid soap during 28-day storage under ambient conditions. A laboratory experimental design was applied, and samples were stored at room temperature with periodic monitoring of temperature and relative humidity (27.2–31.1°C; 65–85%). Physical stability was assessed on days 0, 7, 14, 21, and 28 in triplicate (n = 3) using organoleptic evaluation, homogeneity, pH, foam height, foam stability, and specific gravity. Across the observation period, all formulations remained organoleptically acceptable and homogeneous, with pH and foaming characteristics maintained within acceptable ranges. Endpoint comparisons between day 0 and day 28 within each formulation did not show statistically significant differences for pH, foam height, foam stability, or specific gravity (paired t-test, p 0.05). Overall, under the tested conditions, increasing the extract level from 20% to 30% did not indicate measurable deterioration of the liquid soap’s physical stability over 28 days.
Factors Influencing Antiretroviral Therapy Adherence among People Living with HIV: A Narrative Review Ritha Widyapratiwi; Jenny Pontoan; Kunthi Sekaring Hapsari
Indonesian Journal of Pharmaceutical Education Vol 6, No 1 (2026): January–April 2026
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v6i1.33531

Abstract

Adherence to antiretroviral therapy (ART) remains a pivotal determinant of virological suppression and long-term clinical outcomes among people living with HIV (PLHIV). Nevertheless, adherence estimates and determinants frequently differ across settings, partly because of variation in adherence measurement and contextual influences. This narrative review synthesises evidence on factors influencing ART adherence among PLHIV. A literature search was conducted using Google Scholar and ScienceDirect and complemented by manual screening of reference lists to identify relevant studies published between 2015 and 2025. Studies were included if they reported adherence outcomes and/or determinants among PLHIV receiving ART. Five eligible studies were narratively synthesised because adherence measurement tools and reporting formats were heterogeneous, including pharmacy-based indicators such as proportion of days covered, validated questionnaires such as the Simplified Medication Adherence Questionnaire and the Morisky Green Levine Scale, self-report measures, and biological proxies based on antiretroviral concentrations in hair. Across the included studies, adherence levels ranged from suboptimal to high depending on the metric applied, indicating limited comparability across methods. Determinants that recurrently emerged comprised regimen- and treatment-related factors, psychosocial influences, and health-system or structural constraints, particularly pill burden, adverse effects, regimen line, family or partner support, stigma, mental health, service accessibility, appointment logistics, and continuity of care. Overall, the evidence indicates that ART adherence is shaped by an interplay of individual, treatment, and system-level factors, suggesting that adherence interventions should be multi-component and context-tailored, while future research should improve standardisation and transparency in adherence measurement to strengthen comparability.
Method Validation and Application of Curcumin UV–Vis Assay for Borax in Nuggets in Gorontalo, Indonesia Ishak Isa; Muhammad Taupik; Paramita Musa; Mahdalena Sy. Pakaya; Wiwit Zuriati Uno
Indonesian Journal of Pharmaceutical Education Vol 6, No 1 (2026): January–April 2026
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v6i1.11855

Abstract

Borax (sodium tetraborate decahydrate; Na₂B₄O₇·10H₂O) is prohibited for use in processed foods in Indonesia, necessitating analytically defensible surveillance methods for routine monitoring. This study aimed to validate a curcumin-based UV–Vis spectrophotometric assay and to apply rapid qualitative screening to nugget products marketed in Gorontalo, Indonesia. Qualitative screening was performed using the flame test and turmeric paper test on six samples (A1–C2) collected in October 2025. For the UV–Vis method, wavelength optimisation using a 500 µg/mL borax standard identified 427 nm as the operational measurement wavelength. Calibration standards (1–9 µg/mL) were analysed in triplicate, and validation was conducted for linearity, LOD, LOQ, repeatability precision, and spike-recovery accuracy (80%, 100%, and 120% levels). The method exhibited excellent linearity (y = 0.1082x + 0.0147; R² = 0.9995), with LOD and LOQ of 0.25849 µg/mL and 0.86165 µg/mL, respectively. Repeatability showed 1.40% RSD, while spike-recovery testing demonstrated high trueness (mean recovery 99.403%) with low dispersion (%RSD 0.201–0.252%). All nugget samples were negative by both qualitative screening assays. However, UV–Vis quantitative values for the nugget extracts were not available in the recorded dataset; therefore, borax-equivalent concentrations in mg/kg could not be reported for the marketed samples. Overall, the validated curcumin UV–Vis procedure demonstrates strong analytical performance and is suitable for confirmatory monitoring, provided that future surveillance applies the method directly to each sample extract to enable defensible classification as ND (LOD), LOQ, or quantified (≥LOQ).
Stage at Diagnosis and Surgical Management of Breast Cancer at Dumai Regional Hospital, 2020–2025 Delidios Arimbi; Ami Amelia
Indonesian Journal of Pharmaceutical Education Vol 6, No 1 (2026): January–April 2026
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v6i1.36638

Abstract

Breast cancer remains the most frequently diagnosed malignancy among women and a major contributor to cancer-related morbidity, while late-stage presentation continues to constrain surgical options in many regional referral settings. This study aimed to describe the stage at diagnosis and patterns of surgical management, and to examine the association between clinical stage and type of surgery among breast cancer patients treated at Dumai Regional Hospital, Riau, Indonesia. A retrospective hospital-based study was conducted using medical records from January 2020 to October 2025, with total sampling of eligible cases (n = 137). Variables included age, clinical stage at diagnosis based on the AJCC 8th edition (grouped as stage I–II and stage III–IV), and surgical procedure (conservative surgery, modified radical mastectomy, or biopsy/non-definitive procedures). Descriptive statistics were used to summarise patient characteristics and management patterns. The association between clinical stage and type of surgery was tested using the chi-square test, and effect size was estimated using Cramer’s V. Most patients were aged 40–59 years (58.4%), with a mean age of 52.5 years (SD 11.5), and the majority presented at advanced stages (stage III–IV: 62.8%). Modified radical mastectomy was the predominant procedure (64.2%), while conservative surgery accounted for a smaller proportion. Clinical stage was significantly associated with the type of surgery performed (chi-square = 12.3; df = 2; p 0.001; Cramer’s V = 0.30). These findings indicate a persistent predominance of late-stage presentation in this regional hospital, underscoring the need to strengthen early detection pathways and timely referral to expand eligibility for breast-conserving management.
Association Between Medication Adherence and Tuberculosis Treatment Success: Cross-Sectional Primary Care Study in Indonesia Ami Amelia; Fitria Azzahra; Wili Octavia
Indonesian Journal of Pharmaceutical Education Vol 6, No 1 (2026): January–April 2026
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v6i1.36604

Abstract

Tuberculosis (TB) treatment success in primary care is closely linked to sustained medication adherence. This cross-sectional study assessed the association between adherence to anti-tuberculosis drugs and TB treatment success at Karya Wanita Primary Health Center, Pekanbaru, Indonesia, using routine TB programme records (2024–2025). Eligible records with complete adherence and outcome documentation were included (n = 75). Treatment success was defined as cured or treatment completed, whereas unsuccessful outcomes included failure, discontinuation, or death. Overall, 63 patients (84.0%) were adherent and 62 (82.7%) achieved treatment success. Treatment success was substantially higher among adherent than non-adherent patients (96.8% vs 8.3%), with a significant association by Fisher’s exact test (p 0.001). Adherence was associated with a markedly higher probability of treatment success (RR = 11.62; 95% CI: 1.78–75.92). Strengthening DOTS-aligned adherence support through treatment supporters (PMO), early counselling, reminders, and active tracing may improve outcomes.
Quantification of Water-Soluble Protein from Snakehead Fish (Channa striata) by Bradford UV–Vis and FTIR Profiling Mohamad Adam Mustapa; Ariani H. Hutuba; Widy Susanti Abdulkadir; Fika Nuzul Ramadhani; Muhammad Akbar Khudaifi
Indonesian Journal of Pharmaceutical Education Vol 6, No 1 (2026): January–April 2026
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v6i1.34933

Abstract

Snakehead fish (Channa striata) is widely recognised as a nutritionally valuable aquatic resource and is frequently associated with protein-rich traditional preparations. This study aimed to quantify the water-soluble protein fraction of C. striata using Bradford UV–Vis spectrophotometry and to characterise the corresponding functional groups by Fourier Transform Infrared (FTIR) spectroscopy. The fish flesh was processed to obtain an aqueous (water-soluble) protein isolate, and protein concentration was determined using the Bradford method with UV–Vis measurement at 595 nm. Functional-group profiling of the isolate was subsequently evaluated by FTIR to verify spectral features consistent with protein/peptide structures. The Bradford assay indicated a protein level of 460.6 ± 0.958 mg/g, corresponding to 46.06% within the analysed fraction. FTIR analysis revealed characteristic protein-related bands, including Amide A at 3266.43 cm⁻¹, Amide I at 1635.92 cm⁻¹, and Amide III at 1318.95 cm⁻¹, supporting the presence of peptide bonding patterns in the isolate. Collectively, these findings demonstrate that C. striata yields a measurable water-soluble protein fraction quantifiable by Bradford UV–Vis and confirmable at the functional-group level by FTIR, providing a practical analytical basis for further standardisation and quality-oriented studies.

Page 15 of 16 | Total Record : 152

 12   13   14   15   16 

Filter by Year

2021 2026


Reset
Filter By Issues
All Issue Vol 6, No 1 (2026): January–April 2026 Vol 5, No 3 (2025): September–December 2025 Vol 5, No 2 (2025): May–August 2025 Vol 5, No 1 (2025): January–April 2025 Vol 4, No 3 (2024): September-Desember 2024 Vol 3, No 3 (2023): September-Desember 2023 Vol 3, No 2 (2023): Mei-Agustus 2023 Vol 3, No 1 (2023): Januari-April 2023 Vol 2, No 3 (2022): September-Desember 2022 Vol 2, No 2 (2022): Mei-Agustus 2022 Vol 2, No 1 (2022): Januari-April 2022 (in press) Vol 2, No 1 (2022): Januari-April 2022 Vol 1, No 3 (2021): September 2021 Vol 1, No 3 (2021): September-Desember 2021 Vol 1, No 2 (2021): Mei-Agustus 2021 Vol 1, No 1 (2021): Januari-April 2021 More Issue