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Unit Redaksi IJPE, Gedung FOK, Jurusan Farmasi, Fakultas Olahraga dan Kesehatan Universitas Negeri Gorontalo. Jln. Jenderal Sudirman No. 06, Kota Tengah, Kota Gorontalo, 96128, Gorontalo, Indonesia. Surat Elektronik : redaksiijpe@ung.ac.id Telf/Fax : 0435-821698 / 0435-821698 Phone (Whatshaap) : +6281547458537
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INDONESIA
Indonesian Journal of Pharmaceutical Education
Published by Universitas Negeri Gorontalo
ISSN : -     EISSN : 27753670     DOI : https://dx.doi.org/10.37311/ijpe
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology Medicine & Pharmacology
ndonesian Journal of Pharmaceutical Education (IJPE) adalah junal resmi yang diterbitkan oleh Jurusan Farmasi Universitas Negeri Gorontalo yang bekerja sama dengan IAI (Ikatan Apoteker Indonesia) Provinsi Gorontalo. Artikel pada jurnal ini dapat diakses dan unduh secara online oleh publik (open access journal). Jurnal ini adalah jurnal peer-review nasional, yang terbit tiga kali dalam setahun tentang topik-topik keunggulan hasil penelitian di bidang pelayanan dan praktek kefarmasian, pengobatan masyarakat, teknologi kefarmasian serta disiplin ilmu kesehatan yang terkait erat. Jurnal ini menerima naskah berbahasa Indonesia dan Inggris. Berikut merupakan area-area yang difokuskan oleh jurnal ini Farmasi Klinis Farmasi Komunitas Farmasetika Kimia Farmasi Farmakognosi Fitokimia Naskah yang terpilih untuk dipublikasikan di Indonesian Journal of Pharmaceutical Education akan dikirim ke reviewer yang pakar dibidangnya, yang tidak berafiliasi dengan lembaga yang sama dengan penulis dan dipilih berdasarkan pertimbangan tim editor. Naskah yang diterima untuk publikasi adalah salinan yang diedit untuk tata bahasa, tanda baca, gaya cetak, dan format. Seluruh proses pengajuan naskah hingga keputusan akhir untuk penerbitan dilakukan secara online.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 142 Documents
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Hubungan Pengetahuan Terhadap Tingkat Kepatuhan Minum Obat Anti Hipertensi dewi winni fauziah; Elly Mulyani
Indonesian Journal of Pharmaceutical Education Vol 2, No 2 (2022): Mei-Agustus 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i2.15484

Abstract

Hypertension is a condition where an increase in systolic or diastolic blood pressure ≥ 140/90 mmHg. Success of hypertension therapy is influenced by several factors, one of which is compliance with taking hypertension medication. Adherence to take medication is very important to improve the effectiveness of treatment and prevent complications. Poor adherence to drug consumption is the most frequent cause of failure of antihypertensive therapy. Compliance can be used as a parameter of a patient's level of knowledge in carrying out instructions from medical personnel.  The purpose of this study was to determine the relationship of knowledge of adherence to taking antihypertensive drugs for patients in the work area of the Lebong District Health Center in 2019. The research method used in this study is analytical research using a cross-sectional design which is a research plan of a study to study the dynamics of the correlation between the independent variable (knowledge) with the effect or dependent variable (the level of compliance taking antihypertensive medication) which is observed or collected data at once at the same time. From this study obtained the Odds Ratio (OR) = 3,781 (95% CI: 1,503-9,513) which means someone with less knowledge has a risk of 1.503 times for not compliant to take anti-hypertensive drugs than someone who has good knowledge. There is a significant relationship between knowledge with the level of adherence to take antihypertensive medication in the working area of the Lebong District Health Center.
Effect of HEC (Hydroxyethyl Cellulose) Polymer on Nanoemulsion-Based Curcumin Transdermal Patch Release Rahmatia Is. Kaluku; Robert Tungadi; Nur Ain Thomas
Indonesian Journal of Pharmaceutical Education Vol 2, No 3 (2022): September-Desember 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i3.12025

Abstract

Curcumin a hydrophobic polyphenolic compound and water-insoluble that creates low systemic bioavailability inside the body, has broad pharmacological activity, including anti-inflammation. This study aims to formulate, characterize and evaluate the nanoemulsion based on curcumin through an in vitro transdermal patch preparation. This study starts from formulating a curcumin nanoemulsion solution and characterizing the particle size of curcumin through PSA (Particle Size Analyzer). Further, it formulates the transdermal patch preparation with the smallest curcumin particles within three concentrations (HEC 0,625%, 1,25%, and 2,5%) combined with HPMC 2,5% as polymer. Those formulations are evaluated through organoleptic, thickness, weight uniformity, humidity, and folding resistance tests. In the next step, this study examines the penetration through an in vitro by using a franz diffusion cell within 72 hours. The result shows increasing penetration on each formula where the best penetrations occur in the 15th and 24th hours. It also discovers that the formula containing HEC 2,5% (2c) creates the highest cumulative drug penetration (15,83%). Therefore, it deduces that curcumin nanoemulsion in the transdermal patch has good characteristics and is compatible between drug and polymer.
Uji Aktivitas Krim Anti-Aging Ekstrak Etanol Daun Bayam Merah (Amaranthus tricolor L.) pada Kulit Punggung Kelinci New Zealand yang dipapar Sinar UV-A Ananda Rezky Putri; Suhartinah Suhartinah; meta kartika
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18809

Abstract

The strongest cause of premature aging is sunlight (photoaging), especially UV A rays. Anti-aging creams containing antioxidant compounds can be used in the treatment of aging on the skin of the face. Red spinach leaves (Amaranthus tricolor L.) are a natural source of antioxidants that have very strong potential as an anti-aging. Objectives: This study aims to determine the activity of red spinach leaf extract cream as an anti-aging using New Zealand rabbits exposed to UV-A rays. The skin of the rabbit's back is smeared with cream F1, F2, F3, F4, F5 for 30 days. Parameter observation using a skin analyzer is carried out before, after induction, and after cream smearing. Parameters include percent collagen, elasticity, and moisture. The results of the study were analyzed statistically using one way anova. All test creams pass the physical quality test requirements, but the creams that pass the stability test are F1, F2, F4. The primary irritation test F1, F2, F4 is not irritating whereas F3 is very little irritating. Test the ocular irritation of all creams is not irritating. The test results of anti-aging activity show that F2 provides the most effective anti-aging effect because the percent increase in parameters is the greatest.
Karakterisasi Proses Pembuatan Simplisia Daun Sirih Hijau (Piper Betle) Sebagai Sediaan Obat Penyembuhan Luka paskalis trianus kiko; Wintari Taurina; Mohamad Andrie
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18808

Abstract

Green betel leaf (Piper betle) is used in the manufacture of wound healing preparations, has a function as an antiseptic and eugenol that can kill bacteria. This study aims to characterize the process of making simplicia and simplicia green betel leaf (Piper betle L.) obtained at Jalan Parit Demang, Gg. Kulang Leather, Parit Tokaya No. 6, South Pontianak District, Pontinanak City, West Kalimantan 78121 which is used as raw material for wound healing drug preparations. Green betel leaf simplicia was characterized biologically including habitat, morphology, physically including organoleptic, microscopic, water content, ash content, and acid insoluble ash content, as well as chemically namely phytochemical screening. This characterization is also carried out in the process of making simplicia picking, wet sorting, packing, washing, dry sorting, making simplicia, packaging, and storage. The yield of simplicia was 23.27%. The results of the characterization of green betel leaf are at an altitude of 200-1000 m above sea stage which has a rainfall of 2250-4750 mm in keeping with year. Heart-fashioned leaves, sleek leaf surface, pointed with a leaf period of 6-17.5 cm and a width of 3.5-10 cm.betle leaves have a distinctive aroma, taste slightly spicy, and greenish brown in color. The water content, ash content, acid insoluble ash content and total phenol in green betel leaf simplicia were 12.8%, 7.04%, 3.13%, phenol content 760 nm, absorbance 0.0520 and obtained levels of 23.3379 ppm. Positive for alkaloids, flavonoids, saponins, triterpenoids, tannins.
Formulasi dan Evaluasi Sediaan Gel Nanopartikel Ekstrak Temulawak (Curcuma xanthorrhiza) sebagai Tabir Surya Anjas wilapangga; Deni Rahmat; Rachmaniar Rachmaniar
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18854

Abstract

Temulawak (Curcuma xanthorrhiza) is known as a plant that has many health benefits, including antibacterial, anti-inflammatory, antidiabetic and anticancer. The purpose of this study was to formulate a gel preparation containing temulawak extract nanoparticles as a sunscreen. The gel formed must be evaluated physically including: organoleptic, homogentias, viscosity and spreadability, as well as pH test and SPF examination. Temulawak extract, Nanocurcumin manufacturing method using ionic gelation characterized using particle size analyzer. Results showed that temulawak extract gel and temulawak extract nanoparticle gel did not change color and remained in a homogeneous state. The viscosity of temulawak extract gel is 25098 cPs, while temulawak extract nanoparticle gel is 25673 cPs. The spreading ability of temulawak extract gel was 6.3 cm while the temulawak extract nanoparticle gel formula was 6.5 cm. The pH value of the temulawak extract gel was 5.61 while the pH value of the temulawak extract nanoparticle gel was 5.47. The SPF value of temulawak extract gel was 16.77 while that of temulawak nanoparticle gel was 19.88. Thus, temulawak extract nanoparticle gel can have potential as a sunscreen gel.
Hubungan Tingkat Pengetahuan terhadap Perilaku Swamedikasi Maag Selama Pandemi Covid-19 Shinta Misdariani Nur; Shoma Rizkifani; Nera Umilia Purwanti
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18822

Abstract

Many people in the Tumbang Titi area do self-medication, one of which is ulcer disease because it is considered mild and easy to treat without the supervision of health workers. During the COVID-19 pandemic, self-medication became an alternative choice for people in Tumbang Titi District. This study aims to determine the level of knowledge and behavior of self-medication and whether or not there is a relationship between the level of knowledge and behavior of self-medication. This study is an observational study with cross-sectional design. sampling technique used a purposive sampling with considerations based on inclusion and exclusion criteria for 100 community respondents in Tumbang Titi District. Based on the results of the research on the level of knowledge in the community in Tumbang Titi District, the results were in the good category of 29%, 49% good enough and 22% less good. Self-medication behavior was obtained in good category 19%, good enough 57% and not good 24%. The results of the chi-square test of the level of knowledge and behavior of self-medication showed the results showed the value of Sig. of 0.000 (p 0.005). The conclusion of this study is that the level of knowledge has a fairly good category of 49%, self-medication behavior has a good enough category of 57%, there is a relationship between the level of knowledge and self-medication behavior.
Hubungan Kualitas Hidup Dengan Risiko Depresi Pegawai Publik Universitas X Dimasa Pandemi COVID-19 Shoma Rizkifani; Muhammad Akib Yuswar; Eka Kartika Untari; Nia Resseda
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18836

Abstract

COVID-19 pandemic has had a significant negative impact on the sub-dimension of quality of life, a decrease in quality of life is also correlated with levels of depression. This study aimed to determine the relationship between quality of life and the risk of depression in X University public employees during the COVID-19 pandemic. This research is an analytic observational study and uses a cross-sectional analytic approach, the number of samples is 121 respondents who were selected using a purposive sampling technique. Data were obtained from filling out self-data, quality of life questionnaire (EQ-5D-5L), and depression questionnaire (PHQ-9). The analysis used in this research is a univariate analysis and bivariate analysis. Bivariate analysis using Spearman correlation test. The results showed that most respondents were male, aged 45 years. Respondents have a level of quality of life with a good quality of life category of as much as 57% and a poor quality of life level of as much as 43% and respondents have a level of depression with a mild depression category as much as 26.4%, a moderate depression level as much as 5.8% and a severe depression level as much as 2.5%. The relationship between quality of life and the risk of depression was found to be significant with a significance value of 0.000 with sufficient strength in the negative direction. This study concludes that there is a significant negative relationship between quality of life and the risk of depression in X University public employees during the COVID-19 pandemic.
Hubungan Pengetahuan dan Sikap terhadap Pola Penggunaan Obat Tradisional untuk Swamedikasi di Masyarakat Kota Denpasar Ni Made Maharianingsih
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18886

Abstract

The behavior of self-medication in Indonesian society is quite large and one of the classes of drugs that can be used for self-medication is traditional medicine. The use of traditional medicine is influenced by the knowledge and attitudes of the community. This research aims to determine the relationship between knowledge and attitudes towards patterns of use of traditional medicine for self-medication in the community in Denpasar City. The research method used was an observational analytic cross-sectional study. The location used in this study is the city of Denpasar, with the time of the study taking place in July-September 2020. The research subjects are people who live in Denpasar City aged 20-64 years who buy and use traditional medicines with a total of 400 people. Data were collected by distributing questionnaires to research subjects to measure knowledge, attitudes, and patterns of use of traditional medicines. The results obtained were the pattern of self-medicated traditional medicine in most of the community with the frequency of using drugs more than 4 times a month (23.25%), the most common complaints were headaches (32.5%), the type of traditional medicine was the branded herbal medicine class %), the effect that was felt from the use of traditional medicine was getting better (98.5%) with no side effects (87.25%). Most of the information sources of traditional medicine were from the family (50.25%). Knowledge and attitudes of the people of Denpasar city are mostly classified as high with a percentage of 67.25% for knowledge and 65.50% for attitudes. It can be concluded that there is a significant or moderate relationship between knowledge and the respective patterns of use of traditional medicines, except for the relationship between attitudes and low or weak prices of traditional medicines.
The Correlation between Leukocytes and Bacterial Number from Urine of Type 2 Diabetes Mellitus Patients Using Urine Analyzer Novia Agustina; Diana Pratiwi; Nurul Istiqomah
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.19008

Abstract

Diabetes Mellitus (DM) is a chronic metabolic disorder. DM can occur if the pancreas does not produce enough insulin or the insulin that is produced isn’t effectively used. Patients with diabetes mellitus have a high risk for chronic microvascular complications, including infection. This research aimed to determine the correlation between leukocytes and bacterial number from urine of patients with Type 2 Diabetes Mellitus at the X Hospital Blitar. This research used a cross sectional method, with 47 urine samples of Type 2 Diabetes Mellitus patients by purposive sampling, were tested with urine analyzer. The result showed that the number of high leukocytes was 13 (28%) respondents and normal leukocytes was 34 (72%) respondents. While the number of bacteria from respondents  was normal 21 (45%) and high number was 26 (55%). Based on the Spearman-rho correlation test on SPSS, it can be concluded that there was a significant relationship between leukocytes with bacterial number of urine from Type 2 Diabetes Mellitus patients, with sig = 0,000 (0,05) and the correlation coefficient = 0,515.
Relationship Between Knowledge Level and Compliance in Tuberculosis Patients Erni Anika Sari; Kumala Sari PDW; Defi Rafika
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18774

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis which mostly attacks other organs of the body. The source of transmission is TB patients, especially patients who contain TB germs in their sputum. Someone who has high knowledge has also high awereness of health and high motivation to recover. In the treatmnet of tuberculosis succes depends on the support of the family and the knowledge of the patient. If treatment is not complete, it can lead to the emergence of drug- resistant tuberculosis bacteria. If this happens, the germs will spread and control efforts will be more difficult. Purpose: The purpose of this study was to determine whether there was a relationship between the level of knowledge and adherence to the treatment of pulmonary tuberculosis patients. This study uses a analcyticcal sucrvey design with a cross sectional approach with data collection using a questionnaire to respondents of pulmonary tuberculosis patients who meet the inclusion criteria. The data obtained were collected and analyzed using the SPSS program. The results of the chi-square analysis showed 0.05%, 0.036, which means that there is a significant relationship between the level of knowledge and adherence to the treatment of pulmonary tuberculosis patients.

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