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Unit Redaksi IJPE, Gedung FOK, Jurusan Farmasi, Fakultas Olahraga dan Kesehatan Universitas Negeri Gorontalo. Jln. Jenderal Sudirman No. 06, Kota Tengah, Kota Gorontalo, 96128, Gorontalo, Indonesia. Surat Elektronik : redaksiijpe@ung.ac.id Telf/Fax : 0435-821698 / 0435-821698 Phone (Whatshaap) : +6281547458537
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INDONESIA
Indonesian Journal of Pharmaceutical Education
Published by Universitas Negeri Gorontalo
ISSN : -     EISSN : 27753670     DOI : https://dx.doi.org/10.37311/ijpe
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology Medicine & Pharmacology
ndonesian Journal of Pharmaceutical Education (IJPE) adalah junal resmi yang diterbitkan oleh Jurusan Farmasi Universitas Negeri Gorontalo yang bekerja sama dengan IAI (Ikatan Apoteker Indonesia) Provinsi Gorontalo. Artikel pada jurnal ini dapat diakses dan unduh secara online oleh publik (open access journal). Jurnal ini adalah jurnal peer-review nasional, yang terbit tiga kali dalam setahun tentang topik-topik keunggulan hasil penelitian di bidang pelayanan dan praktek kefarmasian, pengobatan masyarakat, teknologi kefarmasian serta disiplin ilmu kesehatan yang terkait erat. Jurnal ini menerima naskah berbahasa Indonesia dan Inggris. Berikut merupakan area-area yang difokuskan oleh jurnal ini Farmasi Klinis Farmasi Komunitas Farmasetika Kimia Farmasi Farmakognosi Fitokimia Naskah yang terpilih untuk dipublikasikan di Indonesian Journal of Pharmaceutical Education akan dikirim ke reviewer yang pakar dibidangnya, yang tidak berafiliasi dengan lembaga yang sama dengan penulis dan dipilih berdasarkan pertimbangan tim editor. Naskah yang diterima untuk publikasi adalah salinan yang diedit untuk tata bahasa, tanda baca, gaya cetak, dan format. Seluruh proses pengajuan naskah hingga keputusan akhir untuk penerbitan dilakukan secara online.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 142 Documents
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Comparison Study of Caffeine Levels of Coffee Bean (Coffea Sp.) and Brands of Coffee Powder Circulate in Banda Aceh City Andre Prayoga; Zumaira Zumaira
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18913

Abstract

Coffee is one of the plantation commodities that has a fairly high economic value compared to other plantation crops and plays an important role as a source of foreign exchange for the country. Caffeine belongs to the methylxanthine group of compounds. Methylxanthine is a naturally occurring compound and belongs to the xanthine derivative which is a group of alkaloid compounds. To determine the difference in caffeine content between coffee beans and coffee grounds circulating in supermarkets in Banda Aceh. This type of research is a descriptive method with a purposive sampling method used. This research was carried out by analyzing the levels of caffeine in coffee beans and packaged coffee powder circulating in supermarkets in the city of Banda Aceh by UV-Vis Spectrophotometry. The results obtained from the manufacture of standard solutions are 273,20 nm, the correlation coefficient value is r of 0.99995, and the equation y = 0.0483x + 0.01098. From the research data obtained caffeine levels, namely samples of Robusta coffee beans with 0.305%, samples of Meulawi Coffee powder with 0.402%, samples of Arabica Coffee beans with 0.815%, samples of Solong Coffee powder with 1.498%, samples of King Coffee coffee powder with 2.256%. The highest level is in King Coffee powder with 2.256% and the lowest is boiled coffee beans with 0.305%. The difference in caffeine content of each coffee sample is caused by various factors, namely the method of roasting, storage, and treatment.
Face mist Formulation From Yellow Pumpkin (Cucurbita moschata) Extract as An Antioxidant La Sakka; Hasma Hasma
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18960

Abstract

Pumpkin fruit (Cucurbita moschata) is a fruit that contains many benefits for the body, one of which is being able to boost the immune system and having a strong antioxidant content. Face mist is included in skin-refreshing cosmetics that can refresh facial skin, and remove residual oil on the skin. The advantage of this face mist preparation is that it can be easily used and practical to carry anywhere and can quickly seep into the face. This study aims to formulate pumpkin fruit extract into preparations in the form of face mist by carrying out several product analysis processes including organoleptic tests, pH tests, spreadability test and dry time tests so that we can determine the concentrations of face mist preparations that meet the requirements. This research began with the manufacture of pumpkin Simplicia with the drying process after which the pumpkin fruit extract was prepared by maceration method using 70% ethanol to obtain a thick extract. The population and sample in this study are in the Moncongloe area, Paccellekang Village, Maros, South Sulawesi Province. This type of research is experimental research in the laboratory by making 3 formulas consisting of F1 with a concentration of pumpkin fruit extract as much as (1.5 gr), F2 (2 gr), and F3 (2.5 gr). Based on the results of the study it can be concluded that formula F1 and formula F2 are the best formulas because they meet the requirements of SNI standards which are safe and good for use on the skin. Researchers' suggestions for further research are expected to add some product analysis tests on face mist preparations from pumpkin fruit extract.
Penetapan Kadar Paracetamol dalam Jamu di Kota Pontianak Menggunakan Instrumen Spektrofotometri UV-Vis Fajar Nugraha; Hadi Kurniawan; Iga Yastiara
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18876

Abstract

Jamu is a traditional medicine used for generations in Indonesia. There are many regulations for jamu in Indonesia, one of which is the Regulation of the Minister of Health number 7 of 2012. The Minister of Health regulates the prohibition of distribution of jamu containing medicinal chemicals (BKO) that can endanger health. However, there are still many herbs containing BKO circulating in Indonesia, one of which is paracetamol. This study aims to verify the analytical method and measure the levels of paracetamol of jamu in Pontianak City, West Kalimantan. The verification of the analytical methods in this study is the measurement of linearity, accuracy, precision, Limit of Detection (LOD), and Limit of Quantification (LOQ). 3 (three) samples with different brands and indications were obtained through purchases from online shops. UV-Vis spectrophotometry used as a quantitative analytical instrument. The results of the linearity test obtained an r value of 0.999 and an r2 value of 0.999 which met the requirements of ICH, SNI, AOAC, and Eurachem. The results of the accuracy test have a %recovery range of 97.1986-102.2856% which meets the AOAC requirements. The results of the precision test have a %RSD range of 1.8197-7.7966% which meets the AOAC and Horwitz requirements. The results of the LOD calculation are 0.3273 ppm and the LOQ value is 0.9918 ppm. The results of the analysis using UV-Vis spectrophotometry were samples A, B, and C containing paracetamol with levels of 5.1667% each; 18.9809%; and 22,9167%.
Identifikasi Timbal dan Verifikasi Destruksi dengan Metode Spiking Pada Sampel Kangkung Darat Di Kota Pontianak Virgilius Alleandro Tuah Talu; Hadi Kurniawan; Fajar Nugraha
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18891

Abstract

Water spinach is a vegetable that is rich in benefits, apart from the benefits it has, it can also be a mediator for the spread of heavy metals to humans. One of the contaminants that can contaminate Water spinach is lead (Pb). Lead (Pb) is a pollutant that occurs in big cities and has toxic properties. Lead (Pb) contamination in water spinach can occur due to the influence of motor vehicle exhaust, waste, fertilizers and pesticides containing metals. Lead (Pb) contamination in vegetables such as Water spinach can have adverse effects on health such as poisoning and can cause various kinds of disorders such as digestive tract disorders. This study aims to identify lead (Pb) in Water spinach and find out whether the sample preparation method used is good and correct by using spiking method. The samples used in this study amounted to 5 samples spread at different market locations in Pontianak city using the technique purposive sampling. Water spinach samples were prepared using the wet destruction method, then qualitatively tested using 1N NaOH reagent. Method Spiking carried out by taking a standard solution of 1,000 ppm lead (Pb) as much as 1 ml and putting it into the sample to be prepared. The sample that has been prepared is then measured and the value is calculated %Recovery. The results of the qualitative test showed that after the sample was dripped using 1N NaOH reagent there was no white precipitate. The Result obtained in verification of destruction using the spiking method were concentration of 18.7515 ppm and a value %Recovery of 106.8833%. All samples of Water spinach that were tested qualitatively did not contain lead (Pb) and the preparation method used for analysis of ground kale was good and correct.
Identifikasi Natrium Siklamat dan Karakterisasi Bobot Jenis Pada Sampel Minuman Jajanan yang Dijual di Kota Pontianak Andi Andi; Hadi Kurniawan; Fajar Nugraha
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18877

Abstract

Food additives are materials that are added in the food and beverages which has function to influence the quality and form of the food. Sodium cyclamate is one of a food additives that commonly used as a sweeteners in beverages, but the excessive and continuous use can cause dangerous effects to the body. The purpose in this study are to identify sodium cyclamate content qualitatively and to determine the density characteristics of the beverages that are sold in the Pontianak city. The method that are used in this reseacrh is descriptive non-experimental using 5 samples of beverages that are sold in the Pontianak City with purposive sampling technique. Identification of sodium cyclamate in beverages samples is carried out qualitatively using HCl, BaCl2, and NaNO2. Samples which positively contain sodium cyclamate will make white precipitate after the reaction. Characterization of the density of beverages samples is carried out using a pycnometer. The qualitative test result in this research indicate that there are 3 out of 5 samples positive containing sodium cyclamate which is samples of beverages C, D, and E. Density result in sample of beverages C, D, and E respectively are 1,0073 g/mL, 1,0075 g/mL dan 1,0086 g/mL.
Formulasi dan Evaluasi Stabilitas Fisik Sediaan Krim Senyawa Astaxanthin Robert Tungadi; Mahdalena Sy. Pakaya; priliya wati d.as'ali
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.14612

Abstract

This study aims to formulate and evaluate the preparation of an anti-aging cream made from astaxanthin. Astaxanthin has antioxidant activity, as well as other carotenoid compounds. Astaxanthin shows more significant antioxidant activity than ?-carotene; thus,developing astaxanthin compounds in cream preparations is necessary. This type of experimental laboratory research compares three different concentrations of astaxanthin compounds, including formula I (0.5%), formula II (0.75%), and formula III (1%). Evaluation of the astaxanthin compound cream preparations stability included organoleptic observations (smell, color, texture), pH test, homogeneity test, viscosity test, spreadability test, adhesion test, and freeze-thaw test. The results of the quality inspection of organoleptic preparations revealed no difference between the preparations in the form of color, smell, and texture.The homogeneity test showed a homogeneous preparation; the pH test produced was 5.5-5.8, the viscosity test of the preparation produced was 5140 Cp, 5250 Cp, and 7000 Cp, the adhesion test was 6.40-7.83 seconds, the dispersion test was 5-5.9 cm, and the Freeze-thaw test showed that there was no significant change in the pH test, organoleptic test, spreadability, adhesion, homogeneity, and viscosity. Thus, it can be concluded that the three astaxanthin compound cream formulas have good stability.
Hubungan Tingkat Pengetahuan Diabetes Mellitus Terhadap Kadar Gula Darah Pasien Diabetes Mellitus di Puskesmas X umul farida; Djembor Sugeng Walujo; Nanda
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.19052

Abstract

Diabetic Mellitus is a chronic disease caused a limited or inneffective insulin produced by pancreas. Diabetes is a big health problems that has reached an worry level and is a global threat. A knowledge has an important role for behavior. This research is used to look a correlation between level of knowledge with of blood sugar levels in patients of diabetic mellitus at the X Health Center. This research used an analytic survey design with a cross-sectional program. The samples was 93 patients with inclusion criteria in the form in patient of diabetic mellitus at the X Health Center and willing to be respondents. This research was held in December 2022 until January 2023. The research used instrument a questionnaire sheet by DKQ 24. The results of the univariate research were obtained by 64,5% of patient had a good levels knowledge and 35,5% had a not good level of knowledge, 60,2% of patient had a normal blood sugar levels and 39,8% of patient had abnormal blood sugar levels. The bivariate with a Chi-Square statistical test found that there a correlation between the level of knowledge with of blood sugar levels in diabetic mellitus patients at the X Health Center in Kediri City with a P value of 0.014. From this research it can be conclude that there a significant correlation between the level knowledge with of blood sugar levels patients of diabetic mellitus at the X Health Center. Hoped the results this research will give information to the X Health Center to continue providing education about diabetes mellitus to patients as a support the stability of the patient's blood sugar levels with a better life.
Kajian in Silico Daun Sungkai (Peronema canescens) dalam Menghambat Enzim lanosterol 14-α demethylase Jamur Candida albicans Nurul Istiqomah; Safitri Fatikasari; Ariani H. Hutuba
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.19135

Abstract

Candida albicans (C. albicans) is a fungus that causes candidiasis. C. albicans has the enzyme Lanosterol 14- α demethylase. Lanosterol 14-α-demethylase has bioactivity in converting lanosterol to ergosterol, a special sterol found in fungal membranes, which mediates membrane permeability and fluidity. One way to treat candidiasis is to use traditional medicinal plants. Sungkai (Peronema canescens) can be used as an anti-fungal medicine. Drug development efforts can be done using the In silico method. Objectives of this study was to determine the interaction between terpenoid, flavonoid, and phenol compounds in Sungkai leaves against Lanosterol 14-α demethylase in Candida albicans. The research design used was a pre-experimental one-shot case study. Toxtree software was used to test the toxicity of compounds. Test for compound potency using the Pass Online webserver. Docking molecular using PyRx software. Visualization of docking results using Discovery Studio 2019 Software. Physicochemical test of compounds using Lipinski Test. The results showed that the compounds that had a low risk of toxicity were butanoic, catechol, guaiacol, hydroquinone, isopropanol, methanoic acid, palmitic acid, and phytol. Compounds that have anti-fungal activity based on Pharma-expert analysis are butanoic acid, genkwanin, guaiacol, hydroquinone, isopropanol, palmitic acid, and phytol. Compounds that have hydrogen bonds and binding affinity value 10 and RMSD value 2 are butanoic acid, catechol, genkwanin, guaiacol, hydroquinone, isopropanol, methanoic acid, palmitic acid, and quinic acid compounds. These compounds are thought to inhibit the Lanosterol 14-alpha demethylase enzyme in C. albicans. Compounds that comply with Lipinski's rules are anthocyanin and genkwanin compounds. The groups of compounds found in Sungkai leaves that have antifungal activity are the terpenoids, flavonoids, and phenols.
Perbandingan Manifestasi Klinis Penderita Demam Berdarah Zul Fikar Ahmad; Nadila Salsabila Mongilong; Laksmyn Kadir; St. Surya Indah Nurdin; Dewi Rahmawaty Moo
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.19231

Abstract

Dengue hemorrhagic fever has spread throughout the region, especially in tropical and warm climates. Dengue fever has become a global health problem and causes outbreaks almost every year. This study aims to compare the clinical manifestations of DHF patients in pediatrics and adults. This study used a health center-based cross-sectional approach and used secondary data on DHF sufferers from 2019-2022 at the Tutuyan Health Center, namely 72 sufferers. Clinical manifestations of fever are symptoms that generally appear in patients with DHF (100%), and headaches (72.2%), vomiting (40.3%), nausea (34.7%). Meanwhile, the few symptoms found were abdominal pain (15.3%), aches (15.3%), rash (11.1%), joint pain (9.7%), and seizures (8.3%). Abdominal pain, joint pain, aches, nausea, and vomiting are commonly found in adults, while rashes and seizures are commonly found in pediatrics. More efforts are needed to strengthen national programs and thereby reduce the morbidity, mortality, and social and economic burden generated by DHF outbreaks and epidemics
Kepatuhan Minum Obat Antidiabetika Oral Pasien Ulkus Diabetikum Rawat Jalan di Klinik X Pontianak Menggunakan Metode Kualitatif MMAS-8 Yunike Dwi Larasati; Nurmainah Nurmainah; Ressi Susanti
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.19278

Abstract

Compliance is a major factor in determining the success of treatment. Non-compliance with taking medication in patients with diabetes mellitus has an impact on the risk of complications, one of which is diabetic ulcers. Diabetic ulcers are chronic wounds that occur due to hyperglycemia and abnormal blood circulation, which causes an increase in blood sugar levels. This study aims to analyze the level of adherence to taking oral antidiabetic drugs and the factors that influence adherence to taking antidiabetic drugs in outpatient diabetic ulcer patients at X Clinic, Pontianak. This research is a type of cross-sectional research, the sampling technique is purposive sampling. The number of samples that met the inclusion and exclusion criteria was 100 patients. Data was collected by filling out a questionnaire. Medication adherence was measured using the Morisky Medication Adherence Scale (MMAS-8) questionnaire. The results showed that the characteristics of patients who visited the X Clinic Pontianak tended to be 45 years old (85%), female (67%), patients with 5 years of illness (55%), patients with a single type of treatment ( 68%), patients taking metformin (47%), and only 27% of patients adhering to oral antidiabetic drugs. Chi-square analysis showed that there was no significant relationship between age (p=1,000), gender (p=0,966), length of stay (p=0,946), type of treatment (p=0,202) on patient compliance in using antidiabetic drugs. From this study, it can be concluded that age, gender, length of suffering, and type of treatment do not affect adherence to taking oral antidiabetic drugs in diabetic ulcer patients.

Page 7 of 15 | Total Record : 142

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