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Unit Redaksi IJPE, Gedung FOK, Jurusan Farmasi, Fakultas Olahraga dan Kesehatan Universitas Negeri Gorontalo. Jln. Jenderal Sudirman No. 06, Kota Tengah, Kota Gorontalo, 96128, Gorontalo, Indonesia. Surat Elektronik : redaksiijpe@ung.ac.id Telf/Fax : 0435-821698 / 0435-821698 Phone (Whatshaap) : +6281547458537
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INDONESIA
Indonesian Journal of Pharmaceutical Education
Published by Universitas Negeri Gorontalo
ISSN : -     EISSN : 27753670     DOI : https://dx.doi.org/10.37311/ijpe
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology Medicine & Pharmacology
ndonesian Journal of Pharmaceutical Education (IJPE) adalah junal resmi yang diterbitkan oleh Jurusan Farmasi Universitas Negeri Gorontalo yang bekerja sama dengan IAI (Ikatan Apoteker Indonesia) Provinsi Gorontalo. Artikel pada jurnal ini dapat diakses dan unduh secara online oleh publik (open access journal). Jurnal ini adalah jurnal peer-review nasional, yang terbit tiga kali dalam setahun tentang topik-topik keunggulan hasil penelitian di bidang pelayanan dan praktek kefarmasian, pengobatan masyarakat, teknologi kefarmasian serta disiplin ilmu kesehatan yang terkait erat. Jurnal ini menerima naskah berbahasa Indonesia dan Inggris. Berikut merupakan area-area yang difokuskan oleh jurnal ini Farmasi Klinis Farmasi Komunitas Farmasetika Kimia Farmasi Farmakognosi Fitokimia Naskah yang terpilih untuk dipublikasikan di Indonesian Journal of Pharmaceutical Education akan dikirim ke reviewer yang pakar dibidangnya, yang tidak berafiliasi dengan lembaga yang sama dengan penulis dan dipilih berdasarkan pertimbangan tim editor. Naskah yang diterima untuk publikasi adalah salinan yang diedit untuk tata bahasa, tanda baca, gaya cetak, dan format. Seluruh proses pengajuan naskah hingga keputusan akhir untuk penerbitan dilakukan secara online.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 142 Documents
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UJI AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN KECUBUNG (Datura metel L.) TERHADAP BAKTERI Streptococcus pneumonia DAN Klabsiella pneumonia A. Mu’thi Andy Suryadi; Moh Adam Mustapa; Faramita Hiola; Sintiya Basiru
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11776

Abstract

Infectious disease is a disease caused by microbes, including bacteria. One of the microorganisms that often causes infectious disease is Streptococcus pneumoniae and Klabsiella pneumoniae. Based on empirical data, plant that has antimicrobial potential is amethyst leaves (Datura metel L.). This study aims to know the antibacterial activity and concertration of amethyst leaves (Datura metel L.) against Streptococcus pneumoniae and Klabsiella pneumonia. This is an experimental study which includes antibacterial activity test, MIC (Minimum Inhibitor Concertration) test, MFC (Minimum Fungicidal Concertration) test, and bacterial potency test. The finding shows that the antibacterial activity test of amethyst leaves (Datura metel L.) methanol extract is able to inhibit bacterial growth of Streptococcus pneumonia at a minimum inhibitor concertration of 15% and an optimum concertration of 50% with an average of 16.33 mm and 19.30 mm. Meanwhile, for Klabsiella pneumoniae, the minimum inhibitor concertration is 20% and the optimum concertration is 50%, with an average of 13.82 mm and 17.73 mm. this is based on the results of One Way Anova data (a 0.01) with a 99% confidance level. 
Tingkat Kepuasan Pasien Rawat Jalan Terhadap Pelayanan Kefarmasian Di Instalasi Farmasi Rumah Sakit Langit Golden Medika Sarolangun Medi Andriani; Santi Perawati; Siti Nurhaliza
Indonesian Journal of Pharmaceutical Education Vol 2, No 1 (2022): Januari-April 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i1.13247

Abstract

Patient or customer satisfaction is the level of consumer feelings after comparing what he received and his expectations. The purpose of this study was to determine the level of satisfaction of outpatients with respect to pharmaceutical services at the pharmacy installation of Langit Golden Medika Sarolangun Hospital using 5 (five) dimensions of service quality, Reliability, Responsiveness, Assurance, Empathy, and Tangible Evidence This type of research is a descriptive non-experimental research. Observational data collection techniques with the criteria of outpatients and patients' families who redeem prescriptions, patients who can communicate well, and patients who can read and write. The results of these 5 (five) dimensions state patient satisfaction at a hospital pharmacy installation. This study was conducted by means of patients filling out questionnaires and then calculating the percentage of patient satisfaction with the indicators studied. Based on the calculation of the level of patient satisfaction on the Reliability indicator of 78.43%, the Responsiveness indicator of 80.13%, the Assurance indicator of 79.24%, the Empathy indicator of 80.76%, the Direct Evidence indicator of 79.22%.
Skrining Fitokimia dan Uji Aktivitas Antioksidan Kulit Batang Matoa (Pometia pinnata) Dengan Metode 1,1-Diphenyl-2 picrylhidrazyl (DPPH) Hamsidar Hasan; Nur Ain Thomas; Faramita Hiola; Fika Nuzul Ramadhani; Anggun Sasmita Ibrahim
Indonesian Journal of Pharmaceutical Education Vol 2, No 1 (2022): Januari-April 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i1.10995

Abstract

Pometia pinnata is a plant belonging to the Sapindaceae family that spread in the tropics, including Indonesia, which can be used as antioxidants. It is known to contain flavonoid compounds. Flavonoid is a substance that has antioxidants in capturing free radicals because it contains a hydroxyl group which is a reducer and can be beneficial for hydrogen donors to free radicals. This study aims to determine the chemical content and antioxidant activity of Pometia pinnata skin using 1,1-Diphenyl-2-Picrylhidrazyl (DPPH). Sample extraction was conducted using a multilevel extraction method with n-hexane, chloroform, ethyl acetate, and ethanol as solvents. The results showed that Pometia pinnata skin extract contains Alkaloids, Flavonoids, Saponins, Tannins, Steroids, and Terpenoids. While the value of antioxidant activity showed the IC50 value of n-hexane, chloroform, ethyl acetate, and ethanol extracts are 25, 5, 9, 4 µg/mL. The IC50 value indicates that the antioxidant activity is in an extremely strong category.
Analisis Biaya dan Nilai Utilitas pada Pasien Hemodialisis yang Diberikan Terapi Erythropoiesis di Rumah Sakit Madania Madania; Tety Sutriyati Tuloli; Nur Rasdianah; Juliyanty Akuba
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11360

Abstract

Chronic kidney failure is a condition where there is a gradual decline in kidney function. Chronic kidney disease is often followed by complications of anemia. The use of erythropoietin therapy in chronic renal failure patients undergoing hemodialysis requires no small amount of money. This affects the quality of life (utility). The purpose of this study is to measure costs and utility values using the EQ-5D-5L (EuroQol-Five Dimensions) instrument, VAS (Visual Analog Scale), and costs based on the patient's perspective at Prof.Aloei Saboe Hospital. This study is a prospective cross-sectional approach. Data was collected using the EQ-5D-5L and EQ-VAS questionnaires. The subjects of the study were hemodialysis patients as many as 45 met the inclusion criteria. The results showed that the most widely used Erythropoietin therapy was single Hemapo. The results of the calculation of the estimated cost of each hemodialysis patient from the perspective of a patient for one month of therapy are Rp. 7,112,000. The average expenditure of patient transportation costs is Rp. 50,111. The average cost of food for the patient is Rp. 25,000.Utility value based on average Indonesian set value 0.673 (sufficiently feeling well)and VAS score 71.4 (health status is quite healthy).
Evaluasi Kerasionalan Penggunaan Obat Antihipertensi Pada Pasien Hipertensi Rawat Inap RSUD H. Hanafie Muara Bungo Tri Wasilah; Rasmala Dewi; Deny Sutrisno
Indonesian Journal of Pharmaceutical Education Vol 2, No 1 (2022): Januari-April 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i1.13788

Abstract

According to the World Health Organization (WHO), hypertension affects 22% of the world's population. Hypertension is also the cause of death with 23.7% of the total 1.7 million deaths in Indonesia in 2016. Based on the medical record sheet at H. Hanafie Muara Bungo Hospital there are 313 people with hypertension and 78 are included in the inclusion criteria. The aim is to find out the rationale for using antihypertensive drugs at the H. Hanafie Muara Bungo Hospital for the 2019 period in the form of choosing the right drug, right drug indication, right dose and right frequency of administration. The aim is to find out the rationale for using antihypertensive drugs at the H. Hanafie Muara Bungo Hospital for the 2019 period in the form of choosing the right drug, right drug indication, right dose and right frequency of administration. The research method is descriptive observational with data collection using purposive sampling technique. The results on the use of antihypertensive drugs that are most often used are amlodipine CCB (Calcium Channel Blockers) class. Characteristics such as gender have the same percentage, namely 39 patients (50%), hypertension occurs mostly in the age range 56-65 years, and the most diagnosis is stage 2 hypertension (37.2%). Percentage of rational use of antihypertensive drugs from right drug selection 78 patients (85.9%), right drug indication as many as 78 patients (100%) right, right dose 78 patients (100%) right, and the right frequency of drug administration 78 patients (100%) right. The conclusion of this study is the rationale for the use of the most widely used antihypertensive drug is amlodipine, the right choice of drug is 100%, the right drug indication is 100%, the dose is 100% right, and the frequency is 100%.
Karakteristik Pasien dan Penggunaan Obat Pada Pasien Covid-19 Derajat Sedang Hingga Berat Ni Made Maharianingsih; I Ketut Sudirta; Ni Putu Aryati Suryaningsih
Indonesian Journal of Pharmaceutical Education Vol 2, No 2 (2022): Mei-Agustus 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i2.13958

Abstract

The development of cases of COVID-19 (coronavirus disease 2019) in the province Bali to increase until it ranks 10 th in Indonesia. This study aims to determine the characteristics of patients and the description of drug use for COVID-19 patients at Karangasem Hospital Bali for the period April 2020-Aril 2021. This study used a descriptive observational method with a cross-sectional design through a retrospective data search. The number of respondents as a sample was 200 patients with purposive sampling technique. The data collected is in the form of secondary data, which comes from medical records of COVID-19 patients at Karangasem Hospital. The results of the study showed that the most COVID-19 patients in Karangasem RSUD were from adults as many as 109 people (54.5%). Clinical symptoms experienced by all patients were fever with body temperature 38°C for more than 3 days and headache (100%). Patients who had comorbid as many as 196 people (98%) with pneumonia being the highest comorbid as many as 102 people (51%). The length of hospitalization for patients is generally 0-7 days by 69% (138 people). The highest patient status experienced moderate degree of symptoms by 89% (178 people) and severe 11% (22 people). The most drugs given to patients was vitamin C intravenously by 71% (142 people), while antiviral drugs in the form of oseltamivir (tamiflu) became the least by 1% (2 people). The characteristics of moderate-to-severe COVID-19 patients are dominated by male adult patients, have comorbidities (98%), clinical symptoms experienced by all patients are fever for more than 3 days and headache, with hospitalization for more than 3 days. The type of drug that is most often used is for antipyretic analgesics is paracetamol, the type of antibiotic is azithromycin, the type of antiviral is favipiravir, the type of corticosteroid is dexamethasone.
Gambaran Tingkat Kepuasan Pasien Terhadap Pelayanan Kefarmasian di Rumah Sakit Nurchamidin Gobel
Indonesian Journal of Pharmaceutical Education Vol 2, No 2 (2022): Mei-Agustus 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i2.13989

Abstract

Patients are one indicator of the quality of services we provide and patient satisfaction is a capital to get more patients and to get loyal patients (faithful). Loyal patients will reuse the same health services if they need it again. Even loyal patients will invite others to use the same health service facility. The purpose of this study is to describe the level of patient satisfaction. This type of research uses a descriptive method with concurrent data collection. The data collected is in the form of result data (observations and questionnaires). Concurrent data is primary data obtained during direct observation and questionnaires during the research. This research was conducted from the second week of December 2020 until the end of February 2021. The data obtained is based on the answers from respondents to the questionnaire that has been tested for validity and reliability and then distributed. Furthermore, processed and analyzed and seen the percentage level of patient satisfaction which is presented in tabular form. Based on the data obtained from the respondents' answers, it can be concluded that the description of the level of patient satisfaction in the pharmacy installation of ZUS Hospital North Gorontalo is in the good category, with an average percentage of 81%. The criterion aspect of the question that received the most positive response from the respondents was that the service procedures at IFRSUD ZUS Gorontalo Utara were fast and did not bother the patient? (94%) and on the aspect of the criteria the question is that whether the officers are fair in providing services? (63%). Things that need to be done to improve aspects of questions that are still in the sufficient category are by improving the pharmaceutical service process as a whole, conducting supervision and awareness for all parties.
Evaluasi Implementasi Sistem Penyimpanan Obat di Apotek Puput Astreawati; Yulianis Yulianis; Medi Andriani
Indonesian Journal of Pharmaceutical Education Vol 2, No 2 (2022): Mei-Agustus 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i2.14109

Abstract

Improper or inefficient storage makes expired drugs undetected can cost pharmacies. Therefore, in the selection of a storage system, it must be selected and adapted to the existing conditions so that drug services can be carried out in an effective and efficient manner. The purpose of this study is to see the drug storage system based on storage standards at the Jambi City Pharmacy. This study uses a descriptive observational method by making observations (direct observations). Data collection is done by the checklist method. The population of this research is pharmacies in 8 districts of Jambi city. The sample of this research is pharmacies who are willing to give research permits, with a total of 1 pharmacy in 1 sub-district. This research was conducted from May 2021 to July 2021.The results of the research on the study of the implementation of the drug storage system at the Jambi City Pharmacy, namely facilities and infrastructure for drug storage with good criteria 6 pharmacies and very good 2 pharmacies, storage standards with very good criteria in all pharmacies, high alert drug storage with poor criteria in all pharmacies, storage of certain drugs/drug ingredients with very good criteria in all pharmacies The results of this study can be concluded that the drug storage system in Jambi City pharmacies has good criteria 6 pharmacies and 2 pharmacies are very good.
Formulasi dan Evaluasi Sabun Padat Transparan dari Ekstrak Bunga Rosella (Hibiscus sabdariffa L.) Robert Tungadi; Madania Madania; Baiq Husnul Aini
Indonesian Journal of Pharmaceutical Education Vol 2, No 2 (2022): Mei-Agustus 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i2.14060

Abstract

Rosella flower is a plant with an antioxidant effect because it contains anthocyanins included in the flavonoid group. Therefore, it is essential to develop rosella flower extract in the form of soap preparations. This present work formulated and evaluated transparent solid soap preparations with 70% ethanol extract. This laboratory experimental research analyzed transparent solid soap preparations that were made of three formulas with different concentrations of active substances, namely FI (0.5%), FII (1%), FIII (2%). In addition, the evaluation of solid soap preparations involved organoleptic observations (smell, color, shape), pH test, foam height test, and irritation test on volunteers' skin. The results of quality inspection of organoleptic preparations indicated that the higher the concentration of the active substance in solid soap preparations, the less transparent the soap looks; the pH test produced 10.63-11.43; the initial foam height test resulted in 80 mm, and the final rest got 70 mm, 60 mm, and 50 mm; skin irritation tested to volunteers showed a negative reaction. The formulation in this study was formula 1, which produced the best transparent soap. It is concluded that FI, FII, and FIII soap with 70% ethanol extract of rosella flowers can be formulated as transparent solid soap.
Gambaran Penggunaan Obat Off-Label Pada Pasien Pediatrik Rawat Inap di Rumah Sakit Teti Sutriati Tuloli; Nur Rasdianah; Andi Makkulawu; Dizky Ramadani Putri Papeo; Maimun Datau
Indonesian Journal of Pharmaceutical Education Vol 2, No 2 (2022): Mei-Agustus 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i2.11449

Abstract

Off-label drugs can be interpreted as drugs that are used not in accordance with drug information, distribution permits and sales licenses from the Marketing Authorization (MA) related to indications, age, dosage, route of administration and contraindications. The use of off-label drugs in children occurs because of incomplete data on pharmacokinetics, pharmacodynamics and side effect of a drug. It is because clinical research in children is quite difficult and not in accordance with research ethics and morals, so it has the potential to cause errors in treatment and unwanted drug reactions. This study aims to describe the use of off-label drugs in hospitalized pediatric patients at RSUD of Dr. M.M Dunda Limboto, Gorontalo District, Gorontalo Province. This is an  observational study using cross sectional design and retrospective data collection. The sampling technique applies a purposive sampling technique with a total of 155 patients who meet the inclusion criteria during the January-June 2020 period. The finding shows that from 155 patient medical records, there are 172 (16,51%) off-label drug used with a total of 1042 drugs. The off-label drugs used in the indication category are 64,53%, the off-label drugs used in dose category are 17,44%, the off-label drugs used in age category are 14,53%, the off-label drugs used in route of administration category are 3,49% and the off-label drugs used in contraindications category are not found. The are the most off-label drugs used in each category, including domperidone (off-label in indications and dose), rhinofed (off-label in age) and salbutamol (off-label in route of administration).

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