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Pharmaceutical And Biomedical Sciences Journal (PBSJ)
Published by Universitas Islam Negeri Syarif Hidayatullah Jakarta
ISSN : 27152979     EISSN : 27156702     DOI : https://doi.org/10.15408/pbsj
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health
Pharmaceutical and Biomedical Sciences Journal is an official peer-reviewed, open access journal that is managed by the Pharmacy Department, Faculty of Health Sciences, UIN Syarif Hidayatullah Jakarta, Indonesia. This journal publishes original research articles, review articles, as well as short communications covering all aspects of Pharmacy, Pharmaceutical dan Biomedical Sciences in both Bahasa Indonesia and English. The journal includes various fields of Pharmacy, pharmaceutical and biomedical sciences such as: Pharmacology and Toxicology, Pharmacokinetics, Community and Clinical Pharmacy, Pharmaceutical Chemistry, Pharmaceutical Biology, Pharmaceutics,Pharmaceutical Technology, Biopharmaceutics, Pharmaceutical Microbiology and Biotechnology, Alternative medicines, Biochemistry& Biomedic.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 8 Documents
 1 
Search results for , issue "Vol. 6 No. 1 (2024)" : 8 Documents clear
Hubungan Sosiodemografi Pasien dengan Pengetahuan Pasien tentang Pelayanan Informasi Obat menggunakan Telefarmasi (E-Pharmacy) Restinia, Mita; Mustafidah, Mabrurotul; Adhamira, Rania; Kinanti, Annisa Putri
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 1 (2024)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.31900

Abstract

E-pharmacy or telepharmacy is a form of ICT-based health service that facilitates consultation with medical practitioners. Telepharmaceutical services in Indonesia have not been implemented widely. This is because ICT access has not been perfectly spread throughout Indonesia. There is also still little socialization related to telepharmaceuticals, so that the understanding of telepharmaceuticals cannot reach the public, which causes telepharmaceuticals to not being implemented properly. This study aims to determine the relationship between the sociodemographic characteristics of respondents and the level of patient knowledge of drug information services using telepharmacy. This research is a descriptive quantitative correlation research. Respondents in this study amounted to 401 people. Statistical test using Chi Square test obtained p value < 0.05 for age and education test with telepharmaceutical knowledge, which can be concluded that there is a relationship between respondent's age and education with telepharmaceutical knowledge; and p value > 0.05 for the test of gender, occupation, frequency of application use with telepharmaceutical knowledge, which can be concluded that there is no relationship between gender, occupation, frequency of application use and telepharmaceutical knowledge.
Profil Pelayanan Informasi Obat pada Pelayanan Swamedikasi Obat Allopurinol di Apotek Kabupaten Bekasi Putri, Clarisya Pramirusanti; Wulandari, Ainun; Siregar, Tahoma
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 1 (2024)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.35167

Abstract

Tenaga kefarmasian merupakan tenaga kesehatan yang memberikan pelayanan kefarmasian kepada masyarakat, salah satunya Pelayanan Informasi Obat khususnya dalam memberikan pelayanan pengobatan mandiri. Peran apoteker di apotek dapat dikatakan belum maksimal, baik dalam penggalian informasi maupun teknis pelayanan informasi obat. Penelitian ini bertujuan untuk mengetahui layanan informasi obat pada layanan pengobatan mandiri allopurinol di apotek di Kabupaten Bekasi. Jenis penelitian ini menggunakan penelitian deskriptif. Penelitian ini dilakukan secara observasional dengan menggunakan metode simulasi pasien, yaitu simulasi pasien yang telah dilatih. Pemilihan sampel apotek menggunakan metode Probability Sampling dan Cluster Random Sampling dengan jumlah apotek yang ada di Kabupaten Bekasi sebanyak 76 buah yang terbagi dalam 21 kecamatan. Subyek penelitian dalam penelitian ini adalah petugas di bagian apotek yaitu apoteker, asisten apoteker, dan petugas non apotek. Instrumen penelitian yang digunakan adalah checklist yang berisi kriteria informasi yang harus disediakan oleh tenaga farmasi dalam pelayanan informasi obat sesuai Peraturan Menteri Kesehatan Republik Indonesia Nomor 73 Tahun 2016 tentang Standar Pelayanan Kefarmasian di Apotek. Hasil penelitian menunjukkan bahwa penggalian informasi dari pasien dikategorikan buruk dengan nilai 0,16% (≤70%), pemberian informasi obat allopurinol dikategorikan buruk dengan nilai 14,11% (≤70%), sehingga kualitas pelayanan kesehatan baik. pelayanan informasi obat yang dilakukan oleh apoteker (7,57%), oleh asisten apoteker (7,18%), dan oleh petugas non apotek (6,56%), dimana ketiganya termasuk dalam kategori buruk (≤70%). Dari penelitian ini disimpulkan bahwa peran petugas apotek dalam memberikan pelayanan informasi obat allopurinol masih rendah dan perlu ditingkatkan.
Measuring Compliance Therapy in Type 2 Diabetes Mellitus Patients using Proportion of Days Covered (PDC) Method and Its Effect on Clinical Outcomes Anwar, Irvan -; Sabarudin, Sabarudin; Malina, Rachma; Widaningsih, Ayu Dewi; Wijaya, Aurelia Arbaleta; Nurawaliah, Lilis
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 1 (2024)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.37761

Abstract

Diabetes Mellitus (DM) is a chronic disease that occurs when blood glucose levels rise beyond normal limits because the body is unable to produce or use insulin effectively. Therapeutic adherence is one of the causes of normal blood glucose levels and the success of patient therapy. Measurement of therapeutic adherence of dm type 2 patients needs to be carried out to monitor the success of their therapy. This study aims to determine the adherence of antidiabetic therapy using the Proportion of Days Covered (PDC) method and its effect on the clinical outcomes of type 2 DM patients at Sulawesi Tenggara. The research method used is observational research with a descriptive design approach. The sample of this study was 186 people obtained using the Slovin formula. Patients are said to be adherence if their PDC value ≥ 80% and are said to be non-adherence if their PDC value < 80%. The data were analyzed using the chi square test. The results showed that patients adhering to treatment amounted to 130 people (69.9%), while patients who did not comply with treatment amounted to 56 people (30,1%) and there was a significant influence between adherence to antidiabetic therapy on the success of therapy  (clinical outcome) with p value = 0.000 in type 2 DM patients at Sulawesi Tenggara. It was be concluded that most of the patients in this study were adherent to the treatment and there was a significant influence between the adherence of antidiabetic therapy to the success of the therapy (clinical outcomes)
Study of Consumer Satisfaction Levels with E-Pharmacy Services Using the Customer Satisfaction Index (CSI) and Importance Performance Analysis (IPA) Mustafidah, Mabrurotul; Shavira, Rurynta Ferly; Adhamira, Rania; Kinanti, Annisa Putri; Citraningsih, Kinanti
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 1 (2024)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.37922

Abstract

E-pharmacy is one of the efforts to improve pharmaceutical services to make them easier and more efficient. Customer Satisfaction Index (CSI) is a scale that can describe consumer satisfaction with a product or service. Customer satisfaction with e-pharmacy services can be assessed by the value of customer expectations for service quality and the reality of the service performance received. This study aims to examine the level of consumer satisfaction, expectations, and priorities for attribute improvement in the dimensions of e-pharmacy services so that service providers can evaluate and improve their services. Furthermore, the analytical method in this study uses an analysis of the results of the gap based on the Service Quality (Servqual), Customer Satisfaction Index (CSI), and Importance Performance Analysis (IPA). The results of this study indicate that attributes' performance on the dimensions of e-pharmacy services is not satisfactory. Customer satisfaction in e-pharmacy service is 86.11% or in the 'very satisfied' category. Meanwhile, the service attribute prioritized for service providers is to improve the guarantee that the drugs given are in good condition (by showing the drug's expiration date).
Hubungan Antara Tingkat Pengetahuan dan Kepatuhan Penggunaan Obat pada Pasien Tuberkulosis di Salah Satu Puskesmas di Jakarta Pusat Maifitrianti, Maifitrianti; Wiyati, Tuti; Apriliyanti, Netha Apriliyanti
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 1 (2024)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.38174

Abstract

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. Non-compliance with TB treatment can lead to low cure rates, high mortality rates and increased risk of recurrence. Knowledge is very important for TB patients in order to sensitize patients to be compliant in carrying out treatment. This study aims to determine the relationship between knowledge level and adherence to taking medication in TB patients at the Kemayoran District Health Center for the period July - September 2023. This study used a cross sectional method with purposive sampling technique. Respondents of this study amounted to 108 patients, 105 patients met the inclusion criteria and 3 patients met the exclusion criteria. The level of knowledge was assessed using the knowledge questionnaire and the level of compliance was assessed using the Medication Adherence Rating Scale (MARS-5) questionnaire. The relationship between knowledge and adherence was analyzed using the Spearman Rho test. The results showed that most patients had good knowledge as many as 81 patients (77.1%) and patients were compliant in taking medication as many as 75 patients (71.4%). The results of bivariate analysis showed that the level of knowledge had a significant relationship with adherence to taking medication (p<0.05) with a strong correlation value (r 0.660) and positive direction.
Identifikasi DRPs Pasien Gagal Jantung di rawat Inap RSJPD Harapan Kita Tahun 2023 Islam, Zainul; Sari, Desy Puspita
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 1 (2024)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.38486

Abstract

Identifikasi Drug Related Problems (DRPs) pada pengobatan sangat penting dalam rangka mengurangi angka morbiditas, mortalitas dan biaya pengobatan. Hal ini akan sangat membantu dalam meningkatkan efektivitas terapi obat terutama pada penyakit yang sifatnya kronis dan membutuhkan pengobatan jangka panjang, salah satunya adalah penyakit gagal jantung. Penelitian ini untuk mendapatkan gambaran jumlah kejadian DRPs pada pasien gagal jantung di rawat inap RSJPD Harapan Kita Maret – Mei 2023. Penelitian deskriptif noneksperimental dengan pengambilan data prospektif dari rekam medik pasien. Sampel sebanyak 81 pasien yang memenuhi kriteria inklusi. Data dianalisis menggunakan PCNE V9.1 tahun 2020. Pasien yang mengalami DRPs sebanyak 72 pasien (88,9%) dan yang tidak mengalami DRPs sebanyak 9 pasien (11,1%). Gambaran DRPs setiap kategori yang terjadi meliputi 7 pasien (8,05%) kejadian obat yang merugikan terjadi, 70 pasien (80,46%) interaksi obat, 9 pasien (10,34%) tidak ada pemberian terapi meskipun ada indikasi yang jelas dan 1 pasien (1,15%) regimen dosis tidak cukup sering. Kejadian DRPs terbanyak terjadi pada interaksi obat dengan angka kejadian moderate sebanyak 60,55%, minor sebanyak 23,59% dan major sebanyak 14,06%. Dengan melihat gambaran tersebut diharapkan dapat meningkatkan monitoring terhadap pasien untuk meminimalisir angka kejadian DRPs.
Efektivitas Ekstrak Daun Pepaya (Carica papaya L.) sebagai Wound Healing Menggunakan Ikan Zebra Danio rerio Hamilton, 1822 Yang Diinduksi Hiperglikemia sebagai Model Aini, Falihah Nur; Elfita, Lina; Fitriana, Narti
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 1 (2024)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.38957

Abstract

Papaya leaves are known to have antidiabetic and wound-healing activities because they contain flavonoids, alkaloids, tannins, and saponins. Tests of the activity of papaya leaf extract in mouse models have been widely conducted. In this study, the wound healing activity of papaya leaves was carried out using zebrafish as a model, because of their ability to regenerate and 70% similarity to human glucose metabolism. This study aimed to analyze the potential of zebrafish as a model for healing diabetic wounds using 96% ethanol extract from papaya leaves. Zebrafish were divided into six groups, namely normal control, negative control, positive, and papaya leaf extract 125, 187.5, and 250 ppm. The parameters observed were a decrease in blood sugar levels, regeneration of the zebrafish caudal fin, and survival rate of the fish. The results showed that there was an effect of administering papaya leaf extract at doses of 125, 187.5, and 250 ppm respectively to reduce blood sugar levels by an average of 42.67; 44.33; and 72 mg/dL, an increase in fin length of 1; 1.3; 1 mm, and survival rate with a percentage of 91%, 91%, 64%. It was concluded that zebrafish could be used as a test model for diabetic wound healing. Apart from that, the use of 96% ethanol extract from papaya leaves affects the healing of diabetic wounds. Of the 3 doses given with 96% ethanol extract of papaya leaves, the best dose for healing diabetic wounds was 187.5 ppm.
Optimization Parameters of Natural Deep Eutectic Solvent Based on Choline Chloride and Fructose for Extraction of Polyphenol from Jotang (Spilanthes acmella) Stem Putri, Fajar Amelia Rachmawati; Maimulyanti, Askal; Nurhidayati, Isna; Mellisani, Bella; Widarsih, R. Wiwi; Puspita, Fitria; Prihadi, Anton Restu
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 1 (2024)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.39583

Abstract

Natural deep eutectic solvents (NADES) have become popular as an environmentally benign alternative to conventional solvents for extracting natural compounds. In this current research, choline chloride was employed as a hydrogen bond acceptor (HBA) and was mixed with fructose which had the role of a hydrogen bond donor (HBD) to construct NADES. This extracting agent was deployed to separate the polyphenolic compounds from the stem of Jotang (Spilanthes acmella) under prime conditions. The extracted polyphenol was subsequently calculated based on the Folin-Ciocalteu method using gallic acid as the standard solution by UV-Vis spectrophotometer at 760 nm. Corresponding to the research outcomes, the most gainful states of extraction were achieved at a sample weight-to-NADES volume ratio of 1:50, a period of extracting process of 60 min, water content of 20%, and a stirring speed of 80 rpm. The optimized parameters were conceived as the most gainful because they exhibited the most prominent level of polyphenol were described as follows: ratio of sample weight-to-NADES volume and extraction time showed polyphenol content of 25.13 mg GAE/g each, while the others, stirring speed and water content revealed the polyphenol concentration of 25.75 mg GAE/g respectively.

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