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JIFI (Jurnal Ilmiah Farmasi Imelda)
Published by Universitas Imelda Medan
ISSN : 26553147     EISSN : 25977164     DOI : https://doi.org/10.52943/jifarmasi.v5i1.623
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
JIFI (Imelda Pharmacy Scientific Journal) Imelda Imelda College of Health Sciences (STIKes) which is now Imelda University Medan received related articles: 1. Clinical Community Of Pharmacy 2. Pharmaceutical Technology 3. Pharmacy Management 4. Herbal medicines and Chemistry 5. Biology & Pharmacology JIFI (Jurnal Scientific Pharmacy Imelda) also accepts all writings with various disciplines on the condition that the core points remain in the path and scope of pharmaceutical science.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 119 Documents
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UJI AKTIVITAS ANTI BAKTERI EKSTRAK ETANOL 96% DAUN TEH-TEHAN (Acalypha siamensis) PADA BAKTERI Escherichia coli DENGAN MENGGUNAKAN METODE CAKRAM Dina Maya Syari; Patriza, Zahra Sukma
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 6 No. 1 (2022): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v6i1.1120

Abstract

Teh-tehan (Acalypha siamensis) is a plant that has many branches including a bush with a height of 1-2 m. Escherichia coli bacteria can be found in the human intestine, most of these bacteria are harmless, but some can cause serious poisoning in humans such as diarrhea. The purpose of this study was to determine the antibacterial activity of the ethanol extract of tea-tea leaves (Acalypha siamensis) against Escherichia coli bacteria using the disc method. This research is descriptive by using the ratio of the extract concentration of 20%, 30%, 50%, and 80% with a positive control of chloramphenicol and a negative control of aquadest. he results showed that the concentration of ethanol extract had antibacterial activity. Escherichia coli bacteria gave the highest inhibition zone at a concentration of 80% with an inhibition zone diameter of 12.8 mm while the control chloramphenicol was 28.5 mm. Based on the ANOVA data analysis test that there is a significant difference in antibacterial inhibition.
EVALUASI FORMULASI PRODUK NUTRASETIKAL “POWDER DRINK” DARI EKSTRAK BUAH JERUK KUKU HARIMAU (Citrus medica L.) DAN UJI AKTIVITAS ANTIOKSIDANNYA DENGAN MENGGUNAKAN METODE DPPH (2,2-DIFENIL-1PIKRILHIDRAZIL) Gultom, Roby; Amalia, Amalia
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 6 No. 2 (2023): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v6i2.1254

Abstract

Nutraceutical of powder drink products has been made from the fresh extracts of Tiger Nail’s fruits (Citrus Medica L). This research is a laboratory experimental. Fresh extracts were divided into FI (10%), FII (20%) and FIII (40%). The formulations were compounds of extracts, sucroses (sugars) and waters. Organoleptic’s test results were color is white, orange’s aroma, sweet taste and smooth textures. Hedonic’s test showed the color and aroma test of FII showed the panelists more like it (80% and 70%). The texture test of FIII showed the panelists like it very much (70%) and the taste test of FIII showed the panelists were very like it (60%). The pH values were ranged from 6-7. The fastest dissolving time test showed from FI (8 seconds). The highest viscosity test was showed by FIII (0.89 poise). The determination of vitamin C levels using UV-Vis Spectrophotometry showed FIII the highest levels of vitamin C (0.828%). But all antioxidants activity had low activity. FI has the highest IC50 value (51429005 ppm). Anova test value showed 0,005<0.05 that means the antioxidant activitywere significantly different. Tukey test showed the comparison of antioxidant properties between the formulations groups showed a significance value of 0.008 < 0.05.
ANALISIS RASIONALITAS TERAPI PADA PASIEN TUKAK PEPTIK DI INSTALASI RAWAT INAP RS X KOTA SAMARINDA Irham Bakhtiar, Muh.; Mukti, Chera Ananda
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 6 No. 2 (2023): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v6i2.1267

Abstract

Peptic ulcer is one of the most common gastrointestinal diseases and affects almost 10% of the world's population. Ideally peptic ulcer treatment should be highly effective, free of significant side effects, easy to comply with, and cost effective. This study aims to determine the treatment profile of peptic ulcer patients at the inpatient installation of RS X Kota Samarinda and to determine the rationality of treatment for ulcer patients at the inpatient installation of RS X Kota Samarinda. The research was conducted using a retrospective method. Data collection in this study used a purposive sampling technique in accordance with the inclusion and exclusion criteria and obtained 37 samples of medical record data. Based on the results of the study, it was found that the results of the treatment profile in peptic ulcer patients, the most widely used type of therapy was a combination of PPI (proton pump inhibitor) + cytoprotective (mucosal protector) of 54.1% and a combination of PPI (proton pump inhibitor) + antibiotics + cytoprotective of 54.1%. 10.8%. The most widely used drugs were omeprazole (37.9%), sucralfate (27.5%), lansoprazole (6.9%), amoxicillin (6.9%), clarithromycin (6.7%), pantoprazole (5, 7%), ranitidine (5.6%), rebamipide (2.2%), and metronidazole (1.1%). Rationality in peptic ulcer patients on the use of antibiotics with the Gyssens method obtained category 0 in 5 patients (83.3%) and category IVA in 1 patient (16.7%). Rationality in peptic ulcer patients on the use of gastric acid controlling drugs was found to be 97.3% correct indication, 62.2% correct dose, 100% correct duration.
ANALISIS DRPs STATIN DAN ESTIMASI RISIKO ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD) PASIEN DIABETES MELITUS TIPE 2 RAWAT JALAN DI RS “X” SAMARINDA Irham Bakhtiar, Muh.; Novy Yudhistirawati; Hamzah, Hasyrul
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 6 No. 2 (2023): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v6i2.1268

Abstract

Atherosclerotic Cardiovascular Disease (ASCVD) is the main cause of death in patients with diabetes mellitus with a cardiovascular risk that will increase 2-4 times higher than non-diabetic patients. The statin group is a class of drugs recommended by ACC/AHA 2018 in reducing cardiovascular risk in patients with type 2 diabetes mellitus. This study aims to analyze Drug Related Problems (DRPs) of statin drugs in patients with type 2 diabetes mellitus and calculate the estimated risk for the next 10 years. The research was conducted using a non-experimental descriptive analytic method. Data collection was carried out retrospectively through a population of 194 type 2 diabetes mellitus patients at "X" Samarinda Hospital for the period January-September 2022, 11 patient medical record data were obtained through the Total Sampling technique whose sampling complied with the inclusion and exclusion criteria. The results showed that the most commonly prescribed statins were simvastatin 20 mg in 9 patients (82%), and atorvastatin 20 mg in 2 patients (18%). The results of the DRPs analysis showed that there were 4 cases of DRPs consisting of 1 case of underdose (25%), and 3 cases of drugs not being indicated for the existing medical profile (75%). The total risk level of ASCVD based on the calculation of the ASCVD calculator found that 3 patients (27%) had low risk, 4 patients (36%) medium risk, and 4 patients (36%) high risk.
UJI EFEKTIVITAS ANTIBAKTERI SEDIAAN SABUN PADAT TRANSPARAN EKSTRAK ETANOL DAUN CABE RAWIT (Capsicum Frutescens L.) TERHADAP BAKTERI Propionibacterium acne Auliafendri, Novycha; Rila , Etrika Cindy
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 6 No. 2 (2023): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v6i2.1273

Abstract

Cayenne pepper leaves (Capsicum frutescens L.) can traditionally be used as an alternative treatment for acne from natural ingredients. This study aims to determine the effectiveness and concentration of the transparent solid soap formulation ethanol extract of cayenne pepper (Capsicum frustescens L.) leaves in inhibiting the growth of acne-causing bacteria (Propionibacterium acne). The method used in this research is experimental. Making cayenne pepper leaf extract (Capsicum Frutescens L.) by maceration method using 96% ethanol then making a transparent solid soap formulation and testing the effectiveness of antibacterial using disc paper diffusion method against Propionibacterium acnes bacteria by measuring the diameter of the inhibition zone for bacterial growth so that it can known Minimum Inhibitory Concentration (MIC). The concentration of Cayenne pepper leaf extract and the transparent solid soap formula used were (FI) 1%; (FII) 2%; (FIII) 3% and blanks (K+) Ranee soap and (K-) extractless soap. Evaluation of the physical quality of transparent solid soap preparations includes: organoleptic test, pH test, foam power test. From the test results, the average transparent solid soap preparation with a concentration of 1% produced an inhibition zone of 10.7 mm, a concentration of 2% produced an inhibition zone of 11.8 mm, and a concentration of 3% produced an inhibition zone of 12.6 mm. Minimum Inhibitory concentration (MIC) which produced the best ethanol extract of cayenne pepper (Capsicum frutescens L.) leaves was found at a concentration of 1% with a Width of Inhibitory Power (LDH) of 10.7 mm. The One Way Anova test obtained a significance value of 0.000 <0.05, so the results were significant, so there were significant differences between treatments. This means that the use of cayenne pepper leaf extract (Capsicum frutescens L.) has an effect on the growth of Propionibacterium acnes bacteria.
PENGETAHUAN IBU TENTANG PEMBERIAN PARACETAMOL PASCA IMUNISASI DASAR DI UNIT BALAI KESEHATAN IBU DAN ANAK (BKIA) RUMAH SAKIT UMUM IMELDA PEKERJA INDONESIA MEDAN Samgryce Siagian, Hartika
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 6 No. 2 (2023): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v6i2.1279

Abstract

Immunizations must be given to children from birth so that their bodies are protected from dangerous diseases. Complete basic immunizations that have fever side effects are DPT and measles immunizations, while BCG, polio and hepatitis B immunizations cause pain around the injection and redness. Antipyretics are used to treat high fever and seizures due to fever after immunization. This study aims to determine the level of experince of mothers about giving paracetamol after basic immunization to children at the mother and child health clinic (MCH) RSU Imelda Pekerja Indonesia Medan. The sample used in this study was 30 people. This research is a quantitative descriptive study with a time series approach. The results of this study indicate that the characteristics of the mother's greatest level of work are housewives (66.7%) and the highest level of education of mothers is high school (53.3%). The mother's level of experince about giving paracetamol after immunization showed that the mother had a good level of experince (70%). In addition, the type of immunization that was given the most to children was BCG immunization (40%), where the age of the most immunized children was 2 months (20%). In addition, each child who was given paracetamol after BCG immunization was 4 children (13.3%). The average age of mothers who bring their children immunized is 24-26 years old (16.7%).
UJI AKTIVITAS SEDIAAN SALEP DARI EKSTRAK ETANOL KULIT BUAH PISANG BARANGAN (Musa Acuminata colla) TERHADAP BAKTERI PENYEBAB INFEKSI LUKA (Staphylococus aureus) Samosir, Sri Rezeki; Immanuel, Adhe Christie
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 6 No. 2 (2023): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v6i2.1280

Abstract

Skin Fruit Banana goods (Musa acuminate Colla) can used as ingredient blocker bacteria. Research this aim for knowing activity antibacterial preparation ointment from extract skin fruit banana goods (Musa acuminate colla) against Staphylococcus aureus. Method Study this conducted Experimental, extract obtained with use method maceration with solvent 96% followed after that the extract was concentrated with rotary evaporator. Ethanol obtained tested Phytochemicals. The results of screenings showed that all of the extracts from skin fruit banana contained flavonoid, alkaloid, steroid, terpenoid and tannin, then made preparation ointment using Vaseline Album base, Adeps Lanae, Paraffin Liquid, Setyl Alcohol and preparation ointment Extract Skin Fruit Banana goods have Concentration 4%, 6%, 8%. Results this show that skin fruit banana goods (Musa acuminate Colla) can formulated as preparation Ointment and Fulfill requirements test quality preparation ointment among them Test Organoleptic, Test Homogeneity, Ph Test, Test Power spread. The results ofthe antibacterial activity test were analyzed using a sumuran method show that formulation preparation ointment extract skin fruit banana goods (Musa acuminate cola ) with concentration 4%, 6%, 8%. Not could hinder growth bacteria and power block. Concluded that the more increase concentration extract, so power a given block the more big to get zone good inhibit _ in growth bacteria (Staphylococcus aureus).
ANALISIS PERILAKU PENYIMPANAN DAN PEMBUANGAN OBAT MASYARAKAT RW 18 KELURAHAN DUREN JAYA BEKASI Azis, Muhammad Fikry; Rohenti, Iin Ruliana; Maratun Shoaliha
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 7 No. 1 (2023): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v7i1.1287

Abstract

Storage and disposal of drugs is an activity to manage medicines at home. This has become a worldwide concern, because in everyday behavior it is found that storage and disposal are still carried out inappropriately. The lack of community willingness to do this creates problems that will arise in the future. This study aims to determine the behavior of storing and disposing of drugs in RW 18 Duren Jaya Village, East Bekasi. Methods: This study used an analytical survey research method, namely a cross sectional survey. Sampling was carried out in a non-random way, namely purposive sampling technique with inclusion criteria aged 17-55 years and had been storing and disposing of drugs. 95 respondents participated in this study. The results showed that 52 respondents (55%) had unused or expired drugs. Among them have received information about how to dispose of drugs as much as 63%. In addition, almost all respondents received information about drug storage as much as 75%. In the analysis of the level of drug storage behavior, it was found that 92 respondents (96.8%) behaved well and the analysis of the level of drug disposal behavior found that 62 respondents (65.3%) behaved fairly. The conclusion shows that drug storage has been carried out properly while disposal behavior is still lacking, so further socialization is needed regarding good household pharmaceutical waste management.
ANALISIS KADAR PARASETAMOL GENERIK DIBANDINGKAN BERMEREK DAGANG Mariyani; Patala, Recky; Awilia, Nurkhaliza
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 7 No. 1 (2023): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v7i1.1483

Abstract

Paracetamol is a substance that can reduce the fever (antipyretic) and relieve the pain (analgesic). Analysis of the levels of generic and branded paracetamol tablets was carried out to determine whether the levels of the active substance in the preparations met the requirements or not by using the High Performance Liquid Chromatography method. The paracetamol quantitative test obtained the results of the levels in sample A = 94.306%, sample B = 99.986%, sample C = 95.296% and sample D = 94.904%. These results indicate that the level of the active substance paracetamol in each sample still meets the requirements of the Indonesian Pharmacopoeia Edition IV, namely not less than 90% and not more than 110%. Statistical analysis using the t-student test, the results of t-count < t-table (0.026 < 2.35) at a significant level of 5%, with the conclusion that there is no significant difference between generic paracetamol and branded paracetamol were analyzed using High Performance Liquid ChromatographyIV, namely not less than 90% and not more than 110%. Statistical analysis using the t-student test, the results of t-count < t-table (0.026 < 2.35) at a significant level of 5%, with the conclusion that there is no significant difference between generic paracetamol and branded paracetamol were analyzed using High Performance Liquid Chromatography.
POLA PENGGUNAAN OBAT ANTIDIABETES PADA PASIEN RAWAT INAP RSUD ANUTAPURA PALU Budiawan, Erick; Gloria, Yovanka Lista; Wulandari, Ayu
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 7 No. 1 (2023): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v7i1.1484

Abstract

This study aims to determine the pattern of antidiabetic treatment and the accuracy of the use of antidiabetic drugs based on indications, drugs, patients, and doses of use at Anutapura Hospital Palu. This study is a descriptive research method using a cross-sectional method with retrospective data collection based on medical record data for type 2 Diabetes mellitus patients in 2021. Sampling was carried out using a minimized sampling technique with medical record data of 30 patients based on inclusion criteria. The results of this study are patients with Type 2 Diabetes Mellitus, which are female, as many as 16 patients (54%), in the age range of 48-60 years as many as 14 patients (46%), the most widely used oral antidiabetic drug group is Biguanid group (Metformin) as many as 18 patients (70%), the type of insulin drug that was most widely used was Novorapid as many as 13 patients (61.91%), and adjunctive drugs with the highest use of therapy, namely Amlodipine as many as 14 patients with a percentage (7, 4%). Antidiabetic treatment is based on the right indication (100%), right drug (50%), right patient (93%) and right dose (100%).

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