cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Elmiawati Latifah
Contact Email
elmiawatilatifah@ummgl.ac.id
Phone
+6281392212213
Journal Mail Official
journal.psp@ummgl.ac.id
Editorial Address
Universitas Muhammadiyah Magelang, Jl. Mayjen Bambang Soegeng, Glagak, Sumberrejo, Kec. Mertoyudan, Magelang, Jawa Tengah 56172, Indonesia
Location
Kab. magelang,
Jawa tengah
INDONESIA
Jurnal Farmasi Sains dan Praktis
Published by Universitas Muhammadiyah Magelang
ISSN : 25499068     EISSN : 25794558     DOI : -
Core Subject : Health, Science,
Immunology & microbiology Medicine & Pharmacology Public Health
Jurnal Farmasi Sains dan Praktis aims to serve the updated scientific knowledge for international researchers in pharmaceutical sciences. Jurnal Farmasi Sains dan Praktis (JFSP) publishes review article, original article, as well as short communication in the all scopes of Pharmaceutical Science such as Pharmaceutics, Biopharmaceutics, Drug Delivery System, Physical Pharmacy, Pharmaceutical Technology, Pharmaceutical Microbiology and Biotechnology, Pharmacology and Toxicology, Pharmacokinetics, Pharmaceutical Chemistry, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Marketing, Alternative Medicines, Pharmaceutical Management, Pharmacoeconomic, Pharmacoepidemiology, Social Pharmacy, Pharmacy Policies.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 4 Documents
 1 
Search results for , issue "Vol 11 No 3 (September-December 2025)" : 4 Documents clear
PHYSICOCHEMICAL CHARACTERISTICS AND PHARMACOLOGICAL ACTIVITY OF SACHA INCHI SEED OIL (Plukenetia volubilis L.): A LITERATURE REVIEW Saputri, Ulan Mulyani; Irnawati, Irnawati; Sahidin, Sahidin; Arba, Muhammad; Fristiohady, Adryan
Jurnal Farmasi Sains dan Praktis Vol 11 No 3 (September-December 2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v11i3.12719

Abstract

Sacha inchi (Plukenetia volubilis L.) of the family Euphorbiaceae is native to Peruvian in the Amazon forest. SaIn seeds are known to contain a significant fatty acid such as linolenic acid (Omega-3), linoleic acid (Omega-6), and oleic acid (Omega-9). Several studies have shown the benefits of Sacha inchi (SaIn) for various pharmacological activities based on its compound content. The aim of this review article is to provide information about pharmacological activities and describe the physicochemical characteristics of SaIn seed oil. The method used to make this article review is a literature study gathered from national and international journals published in the last ten years through Google Scholar, NCBI-Pubmed, and Crossref with search keys in the form "Plukenetia volubilis L.", "Sacha inchi", "pharmacological activity of Sacha inchi", "physicochemical characteristics of Sacha inchi". Based on the literature review, it was found that the physicochemical characteristics of SaIn seed oil with the observed parameters of peroxide value, iodine number, saponification number and acid number showed different values depending on the extraction method used. SaIn has pharmacological activities as antioxidant, anticancer, antidiabetic, antiobesity, anticonvulsant, anti-aging, antihyperlipidemia, antibacterial and potential for alzheimer therapy.
EVALUATION OF PROPHYLACTIC ANTIBIOTIC USE IN SURGICAL PATIENTS USING THE GYSSENS METHOD AT A PRIVATE HOSPITAL IN YOGYAKARTA Arviani, Septania Dini; Faridah, Imaniar Noor; Amsriza, Fadli Robbi
Jurnal Farmasi Sains dan Praktis Vol 11 No 3 (September-December 2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v11i3.12994

Abstract

Prophylactic antibiotics are used before, during, and up to 24 hours after surgery, and can be administered to patients 30-60 minutes before surgery, must adhere to the principle of “Right Antibiotics”. This study aims to assess the application of prophylactic antibiotics in surgical patients in a private hospital in Yogyakarta to promote rational antibiotic use. This study is quantitative and non-experimental. Data were collected prospectively over a period of 30 days from August 4 to September 4, 2024. The study sample consisted of all surgical patients who received prophylactic antibiotics. Prophylactic antibiotic data were analyzed using the Gyssens method. Out of the data collected, 110 patients received preventive antibiotics, and 97 of these patients met the inclusion criteria. Patient characteristics predominantly included a 46% incidence of cesarean sections. Prophylaxis employed three antibiotics, viz. ceftriaxone in 78 patients (79.38%), cefazolin in 19 patients (19.59%), and cefotaxime in 1 patient (1.03%). The assessment utilizing the Gyssens approach revealed that 31 patients were classified into category V (no indication), 49 patients into category IVA (more effective antibiotics available), and one patient into category I (not suitable during prophylaxis). Sixteen patients in category 0 were included in the reasonable antibiotic regimen. This study states that most antibiotics are not in accordance with the Guidelines for Antibiotic Use established by the Ministry of Health of the Republic of Indonesia in 2021.
DEVELOPMENT OF LABRASOL®-BASED SNEDDS FOR ENHANCED DELIVERY OF COMBINATION PROPOLIS, SEA CUCUMBER, AND CENTELLA ASIATICAEXTRACTS Fitriani, Hannie; Syukri, Yandi; Taher, Muhammad
Jurnal Farmasi Sains dan Praktis Vol 11 No 3 (September-December 2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v11i3.14470

Abstract

The therapeutic efficacy of natural extracts such as propolis, sea cucumber or gamat (Stichopus hermanii), and pegagan (Centella asiatica) is supported by their anti-inflammatory, antioxidant, and regenerative properties. However, their pharmaceutical application is limited due to poor solubility and low bioavailability. This study aimed to develop and characterize a Self-Nanoemulsifying Drug Delivery System (SNEDDS) using Labrasol to enhance the delivery and stability of a combination of these three extracts, that exhibit synergistic effects as tissue regeneration, antimicrobial, anti-inflammatory, and antioxidant properties. SNEDDS formulations were prepared by a high energy method with Labrasol, Tween 80, and propylene glycol. The formulations were evaluated for droplet size, polydispersity index (PDI), zeta potential, and thermodynamic stability test. The optimized SNEDDS exhibited nano-sized droplets (151.13 nm ± 17.26) with low PDI (0.39 ± 0.01) and zeta potential (-50.30 ± 1.04) within the stable range, indicating a uniform, physically stable nanoemulsion, and passed the thermodynamic stability test. In conclusion, the optimized SNEDDS formulation demonstrated nano-sized droplets with low PDI and stable zeta potential, indicating good physical stability.
ANTIBIOFILM ACTIVITY OF FIVE NATIVE PLANTS OF KALIMANTAN ISLAND AGAINST Staphylococcus aureus Wibowo, Joko Priyanto; Wahid, Abdul Rahman; Paramitha, Dewi Setya; Wewengkang, Restu Dara; Nurrahmah, Medina
Jurnal Farmasi Sains dan Praktis Vol 11 No 3 (September-December 2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v11i3.12917

Abstract

Infections caused by Staphylococcus aureus are an increasing concern in the healthcare sector, particularly due to the rise of antibiotic-resistant strains. Natural products provide a promising alternative source for discovering new antibacterial and antibiofilm agents. This study aimed to evaluate the antibiofilm activity of five plant species natives to Kalimantan Island against S. aureus. Plant materials were extracted using the ultrasound-assisted extraction (UAE) method with 70% ethanol at 40 kHz and temperature of 30 °C for 30 minutes. Phytochemical screening was performed using standard qualitative tests to detect major secondary metabolite groups, including alkaloids, flavonoids, tannins, saponins, and terpenoids. The antibiofilm assay was carried out using a spectrophotometric microplate method, where biofilm formation was quantified in the presence of plant extracts (500 ppm) compared to negative control (solvent). Data were analyzed statistically using ANOVA (p < 0.05) followed by post-hoc tests to determine significant differences among samples. Among the tested extracts, the gelinggang extract exhibited the strongest antibiofilm effect, inhibiting biofilm formation by 84.39 ± 7.21 %, followed by sangkareho (70.63 ± 7.29 %), kratom (66.54 ± 6.11 %) and matoa (58.36 ± 5.91 %). While, limpasu showed the weakest antibiofilm activity (18.22 ± 1.21 %) in this study. The observed activity may be attributed to the presence of phenolic and flavonoid compounds known to disrupt quorum sensing and biofilm matrix synthesis. These findings highlight the potential of Kalimantan’s native plants, particularly gelinggang, as promising sources of natural antibiofilm agents for combating antibiotic-resistant S. aureus infections.

Page 1 of 1 | Total Record : 4

 1 

Filter by Year

2025 2025


Reset
Filter By Issues
All Issue Vol 11 No 3 (September-December 2025) Vol 11 No 2 (May-August 2025) Vol 11 No 1 (January-April 2025) Vol 10 No 3 (September-December 2024) Vol 10 No 2 (May-August 2024) Vol 10 No 1 (January-April 2024) Vol 9 No 3 (September-December 2023) Vol 9 No 2 (May-August 2023) Vol 9 No 1 (January-April 2023) Vol 8 No 3 (September-December 2022) Vol 8 No 2 (May-August 2022) Vol 8 No 1 (January-April 2022) Vol 7 No 3 (2021): Supplementary Issue (The 4th National Pharmacy Conference 2021 Universitas Halu O Vol 7 No 2 (2021) Vol 7 No 1 (2021) Vol 6 No 2 (2020) Vol 6 No 1 (2020) Vol 5 No 2 (2019) Vol 5 No 1 (2019) Vol 4 No 2 (2018) Vol 4 No 1 (2018) Vol 3 No 2 (2017) Vol 3 No 1 (2017) Vol 2 No 1 (2016) Vol 1 No 2 (2016) Vol 1 No 1 (2015) More Issue