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Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Published by Universitas Muhammadiyah Surakarta
ISSN : 24773328     EISSN : 28077245     DOI : -
Core Subject : Health, Science, Education, Social, Engineering,
Computer Science & IT Engineering Medicine & Pharmacology Social Sciences Other
The International Summit on Science, Technology and Humanity (ISETH) is organised by Universitas Muhammadiyah Surakarta. This summit aims to provide a platform for researchers and academics to share their research findings with others and meet lecturers and researchers from other institutions and to strengthen the collaboration and networking amongst the participants.
Arjuna Subject : Umum - Umum
Articles 342 Documents
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Search results for , issue "2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)" : 342 Documents clear
Effectiveness of Chemopreventive and Life Style as Breast Cancer Prevention: a Literature Review Min, Diya; Alfajri, Asri; Nurul, Fika; Mugi, Virjinia; Husna, Zahira; Pradani, Ninda
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5504

Abstract

Background: Breast cancer is the most common cancer in women worldwide, including Indonesia. Breast cancer patients have an inherited genetic predisposition, including mutations in genes such as BRCA1 and BRCA2. Breast cancer prevention can be done through various ways, such as healthy lifestyle changes, early screening, and chemopreventive. Purpose : This study aims to assess various breast cancer prevention strategies, both through chemopreventive and lifestyle modification to determine the effectiveness of each treatment. Methods: This study used the PRISMA-ScR method (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews). Article searches were in the form of English articles relevant to the research theme with data for the last 5 years (2020-2024) and types of articles Randomized controlled trial, case control, and prospective cohort studies through PubMed, Science direct, and SpringerLink. Results: This study shows that chemopreventive, particularly low-dose tamoxifen, and lifestyle modification are promising approaches in preventing breast cancer. Low-dose tamoxifen was shown to be effective in lowering breast cancer risk with milder side effects and improved patient compliance. In addition, lifestyle modifications such as healthy diet and physical activity also play an important role in breast cancer prevention. Conclusion: The combination of chemopreventive and lifestyle modification can be a comprehensive strategy to reduce the risk of breast cancer.
Social Media Marketing Activity in Healthcare Services: A Systematic Literature Review Badri, Dwi Septiadi
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5505

Abstract

Purpose: This research is aimed at exploring the role of social media as a strategic capability and how this influences marketing performance in healthcare services. Methodology: Through a systematic literature review approach, this research will explore and synthesize the latest relevant literature, forming a strong knowledge base regarding the concept of social media use for marketing in healthcare services. Results: Descriptive analysis based on the Scopus database reveals research trends using keywords (social AND media AND marketing AND healthcare) reached its peak in 2024 with the United States dominating the area of research. Several new viewpoints emerged, including engagement, brand equity, consumer behavior, and other elements. Applications: This research found and filled existing knowledge gaps, especially in the aspect of social media marketing by healthcare services and its impact on consumers and to provide a basis for further research.
The Relationship between Mean Arterial Pressure and Obesity with Sleep Quality Arum, Dyah Ayu Sekar; Setiawan, Iwan; Fithriyah, Saidatul; Basuki, Sri Wahyu
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5506

Abstract

Purpose: This study is to identify the relationship between mean arterial pressure and obesity with sleep quality. Methodology: This study is an analytical observational study with a cross-sectional approach. Sampling method was simple random sampling and the sample selected was 171 respondents. Data was collected from medical record data of POSKESTREN SMA Boarding School Surakarta and Pittsburgh Sleep Quality Index (PSQI) questionnaire. Results: Fisher test analysis result showed no significant relationship between mean arterial pressure and sleep quality (p=0.116). Chi-square test analysis showed significant relationship between obesity and sleep quality (p=0.0015). Applications/Originality/Value: This study showed the information of relationship between mean arterial pressure, obesity, and sleep quality. This study found that there was no significant relationship between mean arterial pressure and sleep quality. A significant relationship between obesity and sleep quality was found.
The Effect of Radiotherapy on Skin Reactions in Nasopharynx Cancer Patient Putri, Elsya Nur Fadhilla; Prakoeswa, Flora Ramona Sigit; Pramuningtyas, Ratih
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5507

Abstract

Nasopharyngeal cancer is a squamous cell carcinoma with a high frequency in East and Southeast Asia. Radiotherapy is the main treatment method often used in the management of nasopharyngeal cancer. Although effective in destroying cancer cells, radiotherapy often causes significant skin reactions, including radiation dermatitis, which can appear as erythema, desquamation, and even ulceration. These reactions can affect the sufferers' quality of life and interfere with the continuity of therapy. This study aims to explore factors that affect the intensity of radiation dermatitis, including location of radiotherapy and concurrent chemotherapy. In addition, radiation dermatitis management strategies, such as the use of moisturizers, topical steroid therapy, and sun protection, are packaged to accelerate the healing process and reduce symptoms. Assessment criteria such as CTCAE and RTOG are used to assess The intensity of dermal responses. It is expected that a thorough understanding of the causes and management of radiation dermatitis would improve the prognosis for patients with nasopharyngeal cancer and increase the effectiveness of therapy. More research is needed to develop more effective preventative and therapeutic measures for radiation-induced dermatitis.
Reduction of Interleukin-6 after PRP-Exosomes Treatment in A Mouse Model of Androgenetic Alopecia Ellistasari, Endra Yustin; Widhiati, Suci; Julianto, Indah; Rosmarwati, Ervina; Monica, Pristia Widya; Yasmin, Aulia
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5508

Abstract

Purpose: This study aim to determine the role of platelet-rich plasma (PRP) exosomes as anti-inflammatory (IL-6) in a mouse model of androgenetic alopecia. Methodology: There are four group of androgenetic alopecia mice model with no treatment group (control group, K1), group treated with PRP-exosomes (K2), group treated with 5% topical minoxidil (K3) and the last group treated with combination of PRP-exosomes and 5% topical minoxidil (K4). All of the group was evaluated clinically and immunohistochemical examination of IL-6 was performed on the 32nd day. Results: Better hair growth results were obtained in the treatment group compared to the control group. In clinical evaluation, K4 had the best results, followed by K2 and K3. The expression of IL-6 is highest in the K1, followed by K4, K2 and K3 and statistically significant. Applications/Originality/Value: PRP-exosomes can enhance hair growth in androgenetic alopecia mice model. IL-6 expression in the control group is significantly higher than in the treatment group.
Effectiveness of Ethanol Extract of Aegle Marmelos Fruit Flesh on Hela Cell Apoptosis Wulandari, Ervita Sri; Yunitama, Alifa Agil Dhillu; Futana, Ninda Pradani; Izzati, Shaula Nur; Wahyuni, Sri; Kurniawati, Yuwandira
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5509

Abstract

Background: Maja plant (Aegle marmelos) or plant commonly known as mojo, is one of the plants that contains many secondary metabolites, one of which is flavonoids. Flavonoids can be used to induce apoptosis mechanisms in cancer cells, so that specific apoptosis mechanisms in cancer cells become more effective and toxicity to normal cells is minimized. Aim: This study aims to evaluate the effectiveness of ethanol extract of maja fruit flesh (Aegle marmelos) in inducing apoptosis of HeLa cells in cervical cancer. Methodology: The method used includes ethanol extraction from maja fruit flesh and treatment of HeLa cells with various concentrations of the extract. Identification of compound content in Aegle marmelos was carried out by phytochemical tests. Apoptosis measurements were carried out using the MTT Assay method and flow cytometry analysis. Results: The results showed that 96% ethanol extract of Aegle marmelos contained secondary metabolites in the form of alkaloids, saponins, tannins, and flavonoids. The IC50 value of the MTT Assay results of maja fruit flesh extract was 7,573 µg/mL, with an apoptosis percentage of 17.6% and had an effect on inhibiting the growth of HeLa cells in the S phase as measured using the flow cytometry method. Value: The flavonoid content in 96% ethanol extract of maja fruit flesh (Aegle marmelos) has an apoptotic effect on HeLa cells. This is evidenced by the IC50 value index of 7,573 µg/mL, an apoptosis percentage of 17.6%, and the presence of inhibition in the S phase in the cell cycle.
Correlation of Platelet Count, PDW, and MPV with Length of Stay in Children with Dengue Infection Faqihudin, Fadli Rizal; Puspitasari, Metana; Jatmitko, Safari Wahtu; Dewi, Listiana Masyita
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5510

Abstract

Purpose: The research aim to determine and analyze the correlation between platelet count, platelet distribution width, mean platelet volume and length of stay in children dengue virus patients. Methodology: This research used correlative observational study employed a cross-sectional design and included 48 children patients with dengue virus infection treated at PKU Muhammadiyah Sampangan Hospital, Surakarta. Platelet count, PDW, MPV, and LoS data were obtained from medical records. Statistical analysis to evaluate the correlation between these variables. Results: Results The study found platelet count (r = 0.28, p = 0.849), PDW (r = -0.110, p = 0.456), or MPV (r = 0.105, p = 0.477) no significant correlation with the length of stay. The result suggest that these platelet count, PDW, MPV are not acurate predictors of LoS in children dengue patients. Applications/Originality/Value: The platelet count, PDW, MPV are not reliable predictors the length of stay in children with dengue virus infection. This finding suggests for future studies, emphazie the need for a comprehensive clinical assessment rather than relying solely on platelet parameters when managing children dengue patients to predictors the length of stay in children with dengue virus infection and inform doctors in monitoring the course of dengue infection so that it is expected to reduce the incidence dengue infection in children.
Correlation of Mean Corpuscular Hemoglobin, Mean Corpuscular Hemoglobin Concentration and Platelet to Hemoglobin Ratio with the Degree of Dengue Virus Infection in Pediatric Patients Alim, Fika Nurul; Jatmiko, Safari Wahyu; Puspitasari, Metana
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5511

Abstract

Purpose: This study aimed to evaluate the correlation between MCH, MCHC, and PHR with the severity of DVI in pediatric patients. Methodology: A cross-sectional observational study was conducted on 47 pediatric DVI patients at PKU Muhammadiyah Sampangan Hospital, Surakarta. Medical records from January to May 2024 were analyzed. Data were statistically evaluated using Spearman’s test to determine the correlation between variables. Results: Among 47 patients, 57.45% had dengue without warning signs, while 42.55% had dengue with warning signs, with no cases of severe dengue. There was no significant correlation between MCH (p=0.383, r=0.130), MCHC (p=0.457, r=-0.111), or PHR (p=0.064, r=-0.273) and the severity of DVI. Applications/Originality/Value: This study examines the roles of MCH, MCHC, and PHR in pediatric dengue virus infection, finding no significant correlation with disease severity. It provides a basis for future research on alternative hematological markers to enhance clinical assessment. This research introduces PHR as a novel parameter in dengue studies, providing a unique perspective on its potential relevance to disease pathophysiology.
Oculi Sinistra Anterior Uveitis in A 35 Years-Old Man Ramadhanti, Halika Irza; Nugrahani, Ida
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5512

Abstract

Purpose: This case study aims to describe the clinical presentation, diagnosis, and management of a 35-year-old male patient with Oculi Sinistra Anterior Uveitis. It highlights the importance of early intervention in preventing complications, particularly vision impairment. Methodology: The study is based on a case report of a patient presenting with acute unilateral anterior uveitis at the Eye Polyclinic of Karanganyar Hospital. The diagnosis was established through a detailed clinical history, ophthalmologic examination, and symptom analysis. The patient was treated with a combination of topical corticosteroids and antibacterial eye drops, along with oral corticosteroids, to reduce inflammation and prevent infection. Results: The patient presented with symptoms of unilateral eye pain, redness, tearing, and blurred vision. The ophthalmologic examination revealed hyperemic conjunctiva, a cloudy anterior chamber, and a slightly delayed light reflex. Treatment with topical and oral corticosteroids successfully reduced inflammation and improved symptoms. The patient's prognosis was favorable, with expectations of full visual recovery if treatment adherence was maintained. Applications: This case emphasizes the significance of early diagnosis and appropriate treatment of anterior uveitis to prevent severe complications such as glaucoma and cataracts. It also provides insights into the clinical presentation and management strategies that can be applied in similar cases, particularly in regions where epidemiological data on uveitis are limited.
The Relationship between Lifestyle Intervention and Remission of Type 2 Diabetes Mellitus: A Literature Review Wahyuningtyas, Hibha Mahesti; Triastuti, N. Juni; Aribah, Khansa; Arum, Dyah Ayu Sekar; Aulia, Mutia Arsya; Anggrahini, Witrishya
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5513

Abstract

Background: Type 2 diabetes mellitus is a complex and long-term metabolic illness characterized by hyperglycemia, which is brought on by both insulin resistance and decreased insulin production. Type 2 diabetes mellitus may occur for a variety of reasons, including genetics, high amounts of free fatty acids, and beta-cell malfunction. Weight loss, remission, and an improved quality of life were all outcomes of lifestyle treatment for type 2 diabetes mellitus, which centered on regular physical exercise and nutritious diet. Aim: This study aims to investigate the impact of lifestyle changes on the remission of type 2 diabetes mellitus. Method: This article uses a literature review methodology, with a search of international literature through PubMed, Science Direct, and Google Scholar databases with inclusion and exclusion criteria applied. This review follows the PRISMA chart. Results: To examine the existing literature and put the construction of the research procedure in context, preliminary reviews were searched in the PubMed, Google Scholar, database, as well as ScienceDirect. Five writers have spent time since the database's creation exploring the correlation between lifestyle factors and type 2 diabetes episodes or remissions. Efforts to control food consumption, exercise, and cellular app use Lifestyle interventions, such as programs that provide mentorship, may influence the incidence and remission of type 2 diabetes mellitus. Conclusion: There have been promising results in the treatment and even remission of type 2 diabetes mellitus using lifestyle intervention such as diet intake control program, physical activity, monitoring by smartphone application, and mentor support.

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