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Jurnal Ilmiah Sains
Published by Universitas Sam Ratulangi
ISSN : 14123770     EISSN : 25409840     DOI : https://doi.org/10.35799/jis.v22i2.40961
Core Subject : Science, Education, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Mathematics Physics
Jurnal Ilmiah Sains (Journal of Scientific Sciences) is the Journals Published by Faculty of Mathematics and Natural Sciences, Sam Ratulangi University. Jurnal Ilmiah Sains Published Twice a Year, i.e April and October. Jurnal Ilmiah Sains  welcomes full research articles in the area of Mathematics and Natural Sciences from the following subject areas: Mathematics Statistics Computer Science Physics Chemistry Biology
Arjuna Subject : Umum - Umum
Articles 345 Documents
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Efektivitas Penambahan Moving Bed Biofilm Reactor (MBBR) Terhadap Kualitas Air Limbah di Instalasi Pengolahan Air Limbah Pondok Pesantren Mahasiswa Universitas Islam Lamongan Gading Wilda Aniriani; Marsha Savira Agatha Putri; Trisnawati Nengseh
JURNAL ILMIAH SAINS Volume 22 Nomor 1, April 2022
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (505.828 KB) | DOI: 10.35799/jis.v22i1.35562

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh penambahan MBBR terhadap kualitas air limbah domestik Instalasi Pengolahan Air Limbah (IPAL) komunal di Pondok Pesantren Mahasiswa Universitas Islam Lamongan (Ponpesma Unisla). Sejak dibangunnya IPAL komunal belum pernah dilakukan pengujian kualitas air hasil olahan IPAL. Air hasil olahan IPAL tersebut dialirkan lansung pada irigasi pertanian, sehingga kualitas air limbah harus memenuhi standar baku mutu PermenLHK No.P68 Tahun 2016 agar aman dibuang pada lingkungan. Diharapkan penambahan MBBR dapat menurunkan kadar polutan yang ada pada air limbah sehingga aman ketika dibuang pada lingkungan. Data yang dihasilkan pada penelitian ini dideskripsikan menggunakan metode deskriptif analitik dan eksperimental dengan mendesain alat reaktor uji untuk MBBR bekerja untuk menurunkan kadar polutan yang ada pada air hasil olahan  IPAL Pondok Pesantren Mahasiswa Universitas Islam Lamongan. Hasil yang diperoleh dalam pengujian parameter fisika, kimia dan biologi, MBBR dapat menurunkan kadar TSS, COD, BOD dan amonia berturut-turut sebesar 73.57%, 35.50%, 61.75% dan 29.10%. Sedangkan parameter yang mengalami kenaikan yaitu parameter pH kemudian minyak dan lemak sebesar 10.44%, 19.14%. Indeks MPN pada pengujian total coliform berjumlah 8/100 mL. Penelitian ini menyimpulkan bahwa MBBR hanya dapat menurunkan kadar TSS, COD, BOD dan amonia. persentase penurunan yang paling tinggi terdapat pada parameter BOD dan yang paling rendah amonia.Kata kunci: Instalasi pengolahan air limbah; moving bed biofilm reactor; kualitas airThe Addition Efectivity of MBBR on Wastewater Treatment Plant Water Quality Islamic Boarding School Students of Lamongan UniversityABSTRACTThis study aims to determine the effect of the addition of MBBR on the quality of communal Wastewater Treatment Plant (WWTP) domestic wastewater at the Lamongan Islamic Student Islamic Boarding School, the treated water from the WWTP is channeled directly to agricultural irrigation, so that the quality of wastewater must meet the quality standards of the Minister of Environment and Forestry Regulation No. P68 of 2016 in order to be safely disposed of. on the environment.   is expected that the addition of MBBR can reduce the levels of pollutants in wastewater so that it is safe when disposed of in the environment. The data generated in this study were described using descriptive analytical and experimental methods by designing a test reactor. The results obtained in physical, chemical and biological tests based on the parameters tested by MBBR can reduce the levels of TSS, COD, BOD, Ammonia by 73.57%, 35.50%, 61.75%, 29.10%. While the parameters that have increased are the pH parameters then oil and fat by 10.44%, 19.14%. MPN index in total coliform testing is 8/100 mL. MBBR can only reduce levels of TSS, COD, BOD and ammonia.Keywords: Moving bed biofilm reactor; wastewater treatment plant; water quality
Efektivitas Biolarvasida Serai Wangi (Cymbopogon nardus) Dengan Daun Cengkeh (Syzygium aromaticum L.) Terhadap Larva Aedes aegypti Christina L Salaki; Herlina Wungouw; Henny V Makal
JURNAL ILMIAH SAINS Volume 21 Nomor 2, Oktober 2021
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (495.811 KB) | DOI: 10.35799/jis.v21i2.35616

Abstract

Penelitian ini menguji efektivitas kombinasi biolarvasida minyak atsiri serai wangi (Cymbopogon nardus) dengan daun cengkeh (Syzygium aromaticum l.) Terhadap larva nyamuk Ae. aegypti. Penelitian ini bertujuan untuk: (a) menganalisis pengaruh pemberian kombinasi biolarvasida minyak atsiri serai wangi dan daun cengkeh terhadap perkembangan larva Ae. aegypti, (b) menganalisis uji daya bunuh kombinasi biolarvasida serai wangi (sw) dan daun cengkeh (dc) terhadap larva Ae. aegypti, (c) menganalisis uji patogenisitas dari kombinasi biolarvasida serai wangi dan daun cengkeh terhadap larva Ae. aegypti. Uji kombinasi biolarvasida ini dilakukan terhadap larva nyamuk Ae. aegypti instar III  dengan perlakuan variasi kombinasi konsentrasi “SW 2% (P)”, “ SW 0,75% ” + “DC1,25% (P1)”, “SW 1%” + “DC 1% (P2)”, “SW 1,25 %” + “DC 0,75% (P3)” , “DC 2% (P4)”. dan Kontrol air (P-). Themepos (P+). Parameter yang diamati meliputi gejala, persentase mortalitas dan waktu kematian.  Mortalitas larva diamati pada jam ke-6,12,18,24  setelah aplikasi. Perbedaan proporsi mortalitas antar tingkat konsentrasi dengan control diuji dengan metode chi-kuadrat sedangkan lT50 dengan analisis probit.  Hasil penelitian menunjukkan masing-masing kombinasi bahan uji (P,P1,P2,P3 dan P4) tidak memiliki perbedaan pengaruh yang sginifikan sebagai biolarvasida dengan taraf signifikansi sebesar 0,05.. Kesimpulan hasil penelitian ini bahwa kelima konsentrasi bahan uji tersebut tidak memberikan perbedaan pengaruh yang signifikan sebagai biolarvasida. Hal ini menunjukkan bahwa minyak atsiri serai wangi dan daun cengkeh baik diaplikasi secara tunggal maupun dikombinasi memiliki efektifitas larvasida yang sama dengan temephos dalam membunuh larva nyamuk Ae. aegypti. Waktu kematian (LT50)  ekstrak serai wangi 12,72 jam, daun cengkeh 6,71 jam dan kombinasi 6,38 jam.Kata kunci: Biolarvasida; efektifitas; konsentrasi; patogenisitas The Effectiveness of Biolarvacide Essential Oil of Vitronella (Cymbopogon nardus) with Clove Leaves (Syzygium aromaticum.L.) on Ae. aegypti Mosquito Larvae ABSTRACTThis study tested the effectiveness of the biolarvicide combination of citronella essential oil (cymbopogon nardus) and clove leaf (syzygium aromaticum L.) against the larvae of Ae. aegypti. This study aims to: (a) analyze the effect of giving a combination of biolarvicides of citronella essential oil and clove leaves on the development of Ae. aegypti, (b) analyzing the killing power of the combination of citronella (sw) and clove leaf (dc) biolarvicides against Ae. aegypti, (c) analyzing the pathogenicity test of the combination of citronella and clove leaf biolarvicides against the larvae of Ae. Agypti. This biolarvicide combination test was carried out on the larvae of Ae. aegypti instar iii with treatment variations in the concentration combination “SW 2% (P)”, “SW 0.75%” + “DC1.25% (P1)”, “SW 1%” + “DC 1% (P2)”, “SW 1.25%” + “DC 0.75% (P3)” , “DC 2% (P4)”. and Water control (P-). Themepos (P+). Parameters observed included symptoms of mortality percentage and time of death. Larval mortality was observed at 6, 12, 18, 24 hours after application. The difference in the proportion of mortality between concentration levels and control was tested by the chi-square method while the lt50 method was tested by probit analysis. The results showed that each combination of test materials did not have a significant difference in effect as a biolarvicide with a significance level of 0.05. The conclusion of this study was that the five concentrations of the test material did not give a significant difference in effect as a biolarvicide. This indicates that the essential oils of citronella and clove leaves, either applied singly or in combination, have the same larvicidal effectiveness as temephos in killing the larvae of Ae. aegypti. Time of death (lt50) citronella extract 12.72 hours, clove leaf 6.71 hours and the combination 6.38 hours.Keywords: Biolarvicides; effectiveness; concentration; pathogenicity
Aktivitas Antihipertensi Ekstrak dan Fraksi-Fraksi Daun Avokad (Persea americana Mill) pada Tikus Jantan dengan Parameter Sistolik dan Diastolik Novi Elisa; Aloysius Barry Anggoro; Erwin Indriyanti
JURNAL ILMIAH SAINS Volume 21 Nomor 2, Oktober 2021
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4747.163 KB) | DOI: 10.35799/jis.v21i2.35625

Abstract

Penyakit kardiovaskuler yang terjadi di Indonesia berawal dari penyakit menular kemudian beralih menjadi tidak menular, salah satunya hipertensi. Tujuan dari penelitian ini untuk mengetahui skrining fitokimia dan hasil uji KLT ekstrak dan fraksi-farksi daun avokad pada tikus jantan yang dibuat model hipertensi dengan induksi NaCl dan prednison.  Pengujian ini dilakukan selama 28 hari menggunakan alat Blood Presure Analizer Tail Caff dengan kelompok perlakuan kontrol normal, positif, negatif, ekstrak dosis 75mg/kgbb, 150mg/kgbb, 250mg/kgbb dan fraksi air, etil asetat, n-heksana masing-masing kelompok berisi 5 ekor tikus. Pengukuran tekanan darah dilakukan pada T0 (belum diberi perlakuan), T1, T2, T3 (induksi NaCl dan Prednison), T4 (diberikan dosis ekstrak dan dosis fraksi). Hasil uji skrinning fitokimia positif flavonoid dan uji KLT dimana nilai Rf yang dihasilkan setelah percobaan KLT dengan metode penyinaran UV 254, ekstrak daun alpukat dengan menggunakan baku kuersetin yang dihasilkan Rf 0,75, fraksi air 0,82, n-heksana 0,93, etil asetat 0,82 dari hasil tersebut dapat dibuktikan terjadi penurunan aktivitas tekanan darah. Hasil persentasi penurunan ekstrak dan fraksi-fraksi daun alpukat menunjukkan dosis efektif ekstrak 250mg/kgbb yaitu 5,87/10,96% sig > 0,05 berbeda makna dengan kelompok negatif dan fraksi etil asetat 5.71/14.53%. sig > 0,05 berbeda makna dengan kelompok negatif.Kata kunci: Antihipertensi; daun avokad; diastolik; sistolik; tikus Anti-Hypertension Activity of Avocado (Persea americana Mill) Leaves Extracts and Fractions in Male Rats with Systolic and Diastolic ParametersABSTRACTOne of cardiovascular diseases that occur in Indonesia that start from infectious diseases and then turn into non-infectious diseases is hypertension. This study aimed to determine the phytochemical screening and TLC test results of avocado leaves extract and fractions in hypertension-modeled male rats through induction of NaCl and prednisone. This test was done in 28 days used Blood Pressure Analyzer Tail Caff with normal, positive, negative control treatment groups, extract doses of 75mg/kgbb, 150mg/kgbb, 250mg/kgbb and water, ethyl acetate, n-hexane fractions for each group. Each group contains 5 rats. Blood pressure measurement was done at T0 (untreated), T1, T2, T3 (induction of NaCl and Prednisone), T4 (given extract dose and fraction dose). The results of phytochemical screening test were positive for flavonoids and the TLC test, where the Rf value produced for avocado leaves extract after TLC test with UV 254 irradiation method, using quercetin standard produced was 0.75, water fraction was 0.82, n-hexane was 0.93, ethyl acetate was 0.82. These results then proved with decrease in blood pressure activity. The results of decreases in percentage of avocado leaves extract and fractions showed that the effective dose of extract 250mg/kgBW was 5.87/10,96% sig > 0.05, which was significantly different from negative group and ethyl acetate fraction was 5.71/14.53%. sig > 0.05 significantly different with negative group.Keywords: Antihypertensive; avocado leaves; diastolic; rat; systolic
Tingkat Kebisingan dan Perambatan Suara Akibat Bunyi Luar Pada Gereja Masehi Injili Minahasa (GMIM) Kampus Unsrat dan GMIM Bethesda Manado Sangkertadi Sangkertadi; Ronald Manganguwi
JURNAL ILMIAH SAINS Volume 21 Nomor 2, Oktober 2021
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1395.788 KB) | DOI: 10.35799/jis.v21i2.35630

Abstract

Penelitian ini bertujuan untuk mengetahui kontribusi dinding dan arsitektur ruang serta jarak gedung ke jalan terhadap reduksi bising dari luar kedalam bangunan, dan distribusi bunyi yang terjadi. Studi kasus pada 2 gereja yaitu gereja GMIM Kampus Unsrat dan gereja GMIM Bethesda Ranotana di Kota Manado. Sebuah sumber bunyi di letakkan di luar ruang dekat pagar pada jarak 12 m terhadap gedung, dengan kuat bunyi konstan namun bervariasi antara 60 sampai dengan 100 dB dengan tahapan setiap 10 dB. Kuat bunyi dihitung dan diukur pada setiap jarak 2 m diruang luar dan dalam Gereja. Pengukuran menggunakan alat sound level meter. Perhitungan menggunakan teori akustik ruang dan software I_Simpa. Hasilnya menunjukkan bahwa konfigurasi arsitektur selubung dan ruang bangunan kedua gereja tersebut dalam keadaan kosong hanya mampu mereduksi bising sebesar 2.2 dan 3.7 dB, dengan jendela terbuka. Dengan sumber suara 100 dB di ruang luar, hasil pengukuran di ruang dalam pada kedua gereja mencapai 69.3 dB(A) dan 56.4 dB(A). Rentang bunyi tersebut masih tergolong bising dan belum memenuhi syarat kenyamanan bunyi untuk jenis bangunan ibadah menurut SNI. Visualisasi distribusi bunyi dengan menggunakan software I_Simpa, menunjukkan peran bukaan pintu dan jendela yang menyebabkan kebocoran bunyi kedalam ruangan.Kata kunci: Akustika;  bising; dinding; gereja Noise Level and Sound Propagation Due to Outside Sound at GMIM Church Unsrat Campus and GMIM Bethesda Manado ABSTRACTThis research aims to determine the contribution of walls and architectural interior, and the distance of the building to the road to the reduction of noise from outside into the building as well as the distribution of sound that occurs. Case studies on 2 churches: the GMIM Church of Unsrat Campus and the GMIM Bethesda Ranotana Church, both in Manado City. A sound source was placed outside the room near the fence at 12 m from the building. The sound source was constant but varied from 60 to 100 dB with steps every 10 dB. Sound reception was calculated and measured every 2 m distance at outside and inside. Measurements were carried out using sound level meter. Calculations by acoustic theory and I_Simpa software. The results show that the churches when room is empty, had only able to reduce the noise by 2.2 and 3.7 dB, with opened windows. When a 100 dB sound source was applied, the measurement results in the indoor of the two buildings reached 69.3 dB(A) and 56.4 dB(A). Graphical visualizations of sound distribution by using I_Simpa software, showed the role of door and opened window that cause sound leakage into the room.Keywords: Acoustic; church; noise; wall
Antibacterial Activity Testing on APMS (p-Methoxy Cinnamic Acid) Against Escherichia coli Bacteria Ahmad Fuad Masduqi; Erwin Indriyanti; Rahmawati Salsa Dinurrosifa
JURNAL ILMIAH SAINS Volume 21 Nomor 2, Oktober 2021
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (650.184 KB) | DOI: 10.35799/jis.v21i2.35684

Abstract

This study aims to determine whether the compound APMS (p-methoxy cinnamic acid) has the antibacterial activity of Escherichia coli and to determine the effective concentration of the compound APMS (p-methoxy cinnamic acid) in inhibiting the growth of Escherichia coli bacteria. This research begins with the synthesis of APMS obtained through the knoevenagel condensation reaction with the sonochemical method. The synthesized compounds were tested organoleptically and their melting points were measured. The structure of the results was elucidated using FT-IR and GC-MS, then tested the antibacterial activity of APMS compounds against Escherichia coli. Data analysis with SPSS, 99% confidence level (p<0.01) and continued with ANOVA test. The compound synthesized by APMS is in the form of fine crystals with a glossy white color, has a characteristic odor, and produces a % yield of 92.71%. The level of p-methoxy cinnamic acid (APMS) produced from this study was 95% using the GC-MS Instrument. APMS compounds have antibacterial activity against Escherichia coli. The average inhibition zone formed at a concentration of 5%; 10%; and 15% respectively are 0.695 cm; 0.727 cm; and 0.855 cm The optimal concentration of this study was at a concentration of 15% which gave the greatest inhibitionKeywords: Antibacterial; Escherichia coli; p-Methoxy cinnamic acidUji Aktivitas Antibakteri Senyawa APMS (Asam p_Metoksi Sinamat) Terhadap Bakteri Escherichia coli  ABSTRAKPenelitian ini bertujuan untuk mengetahui apakah senyawa APMS (Asam p-metoksisinamat) memiliki aktivitas antibakteri Escherichia coli dan mengetahui konsentrasi efektif dari senyawa APMS (Asam p-metoksisinamat) dalam menghambat pertumbuhan bakteri Escherichia coli. Penelitian ini diawali dengan sintesis APMS ini didapatkan melalui reaksi kondensasi knoevenagel dengan metode sonokimia. Senyawa hasil sintesis diuji organoleptis dan diukur titik leburnya. Struktur hasil dielusidasi menggunakan  FT-IR dan GC-MS, kemudian uji aktivitas antibakteri senyawa APMS terhadap Escherichia coli. Analisis data dengan SPSS, tingkat kepercayaan 99% (p<0,01) dan dilanjutkan uji ANOVA. Senyawa hasil sintesis APMS berupa kristal halus berwarna putih mengkilap, memiliki bau khas, dan menghasilkan % yield sebesar 92,71%. Kadar Asam Para Metoksisinamat (APMS) yang dihasilkan dari penelitian ini sebesar 95% menggunakan Instrumen GC-MS. Senyawa APMS memiliki aktivitas antibakteri terhadap Escherichia coli. Rataan zona hambat yang terbentuk pada konsentrasi 5%; 10%; dan 15% secara berturut adalah 0,695 cm; 0,727 cm; dan 0,855 cm Konsentrasi yang optimal dari penelitian ini adalah pada konsentrasi 15% yang memberikan daya hambat yang paling besar.Kata kunci:  Antibakteri; Asam p-metoksi sinamat; Escherichia coli
Kepadatan Populasi Cacing Tanah pada Perkebunan Kelapa Sawit di Desa Salang Tungir Kecamatan Namorambe Jhon Kevin Purba; Rama R Sitinjak; Nur Ariyani Agustina; Julaili Irni
JURNAL ILMIAH SAINS Volume 22 Nomor 1, April 2022
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (682.319 KB) | DOI: 10.35799/jis.v22i1.35703

Abstract

Penelitian ini bertujuan untuk menganalisis kepadatan populasi cacing tanah di perkebunan kelapa sawit dengan perbedaannya pada strata umur kelapa sawit di Desa Salang Tungir Kecamatan Namorambe.Metode yang digunakan adalah metode survey dengan teknik pengambilan sampel cacing tanah secara hand sorting pada stasiun I (TBM) dan stasiun II (TM). Analisis data untuk kepadatan hingga indeks nilai penting cacing tanah digunakan rumus tertentu, dan untuk  perbedaan kepadatan digunakan uji T. Hasil penelitian menunjukkan bahwa cacing tanah di perkebunan kelapa sawit TBM terdapat 3 jenis: Pontoscolex corethrurus, Pheretina sp., dan Lumbricus. Kepadatan relatif dan indeks nilai penting yang tertinggi ditemukan pada Pheretina sp. yaitu 36,09% dan 69,42%. Sedangkan pada TMterdapat 4 jenis: Pontoscolex corethrurus, Pheretina sp., Lumbricus, dan Microscolex. Kepadatan relatif dan indeks nilai pentingnya ditemukan pada Pontoscolex corethrurus yaitu secara berurut 30,56% dan 55,63%. Nilai kepadatan cacing tanah ditemukan lebih tinggi pada perkebunan kelapa sawit yang berumur 4 tahun.Kata kunci: Cacing tanah; Elaeis quineensis Jacq; kepadatan Earthworm Population Density in Oil Palm Plantation inSalang Tungir Village, Namorambe District ABSTRACTThis study aims to analyze the population density of earthworms in oil palm plantations with the differences in the age strata of oil palm in Salang Tungir Village, Namorambe District. The method used is survey method with earthworm sampling technique by hand sorting at station I (TBM) and station II (TM). Analysis of data for density to index of significance of earthworms used a certain formula, and for differences in density used the T test. The results showed that there are 3 types of earthworms in TBM oil palm plantations: Pontoscolex corethrurus, Pheretina sp., and Lumbricus. The highest relative density and significant value index were found in Pheretina sp, namely 36.09% and 69.42%, respectively. While in TM there are 4 types: Pontoscolex corethrurus, Pheretina sp., Lumbricus, and Microscolex. The relative density and significance index found in Pontoscolex corethrurus were 30.56% and 55.63%, respectively. Earthworm density values were found to be higher in oil palm plantations aged 4 years.Keywords: Earthworm; Elaeis quineensis Jacq; density
Senyawa Katekin (Flavonoid) dari Kulit Batang Chisocheton balancae C.DC (Meliaceae) Dewa G Katja; Sisilia A Mantiri; Max R.J Runtuwene; Unang Supratman; Erina Hilmayanti
JURNAL ILMIAH SAINS Volume 21 Nomor 2, Oktober 2021
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (633.297 KB) | DOI: 10.35799/jis.v21i2.35777

Abstract

Senyawa katekin (flavonoid) dengan rumus molekul C15H14O6  telah diisolasi dari kulit batang chisocheton balancae C.DC (Meliacea). Penelitian ini bertujuan untuk mendapatkan senyawa katekin (flavonoid). Sampel dimaserasi dengan metanol dan dipartisi dengan pelarut etil asetat. Hasil partisi etil asetat dipisahkan dengan teknik kromatografi dan dihasilkan isolat murni berupa kristal berwarna putih (5,5 mg) dengan titik leleh 175-1770C dengan serapan maksimum pada panjang gelombang 280,30 nm. Struktur kimia senyawa katekin  diidentifikasi dari  data-data spektroskopi meliputi 1H-NMR, 13C-NMR dan DEPT 1350, serta perbandingan dengan data spektroskopi yang diperoleh dari literatur. Hasilnya menunjukkan bahwa kulit batang Chisocheton balancae C.DC (Meliaceae) merupakan senyawa katekin (flavonoid).Kata kunci: Chisocheton balancae C.DC; katekin ; meliaceae Catechin Compound (Flavonoid) from Chisocheton balancae C.DC (Meliaceae) BarkABSTRACTA catechin compound (flavonoid) with the molecular formula C15H14O6 has been isolated from  Chisocheton balancae C.DC (Meliacee) bark. This study aims to determine the chemical structure of catechins (flavonoids).  The sample is macerated with methanol and partitioned with ehtyl acetate as solvent. The results of the partitioning of ethyl acetate were separated by chromatographic techniques and pure isolates were produced in the form of white crystals (as much as 5,5 mg) with a melting point of 175-1770C and maximum absorption at a wavelength of 280,30 nm. The chemical structure of catechin compound was identified on the basis of spectroscopic data including 1H-NMR, 13C-NMR and DEFT 1350 as well as comparison with spectroscopic data obtained from the literature. The results shows that the bark of  Chisocheton balancae C.DC (Meliaceae) contained catechin compound.Keywords: Catechin; meliaceae; Chisocheton balancae C.DC
Analisis Clustering K-Medoids Berdasarkan Indikator Kemiskinan di Jawa Timur Tahun 2020 Febiyanti Alfiah; Almadayani Almadayani; Danial Al Farizi; Edy Widodo
JURNAL ILMIAH SAINS Volume 22 Nomor 1, April 2022
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1.77 KB) | DOI: 10.35799/jis.v22i1.35911

Abstract

 Keberadaan pandemi COVID-19 di Indonesia, mengakibatkan kemiskinan di Indonesia semakin tinggi terutama di Jawa Timur yang menjadi satu diantara provinsi lain dengan kasus COVID-19 tinggi di Indonesia. Tujuan penelitian ini yaitu mengetahui pengelompokan kabupaten/kota di Jawa Timur yang mempunyai kesamaan karakteristik berdasarkan indikator kemiskinan tahun 2020. Penelitian ini menggunakan data yang didapatkan dari Badan Pusat Statistik. Metode yang digunakan ialah metode k-medoids clustering yang merupakan metode partisi clustering guna pengelompokan n objek ke dalam k cluster. Berdasarkan hasil penelitian, diperoleh pengelompokan karakteristik masing-masing cluster yang dibentuk berdasarkan nilai indikator kemiskinan di Jawa Timur tahun 2020 sebanyak 2 cluster. Dimana 30 kabupaten/kota pada cluster 1 dan dan 8 kabupaten/kota pada cluster 2. Cluster 1 memiliki karakteristik Persentase Rumah Tangga yang Mempunyai Sanitasi Layak, Angka Harapan Hidup, dan Persentase Angka Melek Huruf Umur 15-55 Th tinggi. Sedangkan cluster 2 memiliki karakteristik Persentase Rumah Tangga Miskin Penerima Raskin, Persentase Penduduk Miskin, dan Persentase Pengeluaran Perkapita untuk Makanan dengan Status Miskin tinggi. Kata kunci: Clustering; Jawa Timur; K-medoids; kemiskinan  K-Medoids Clustering Analysis Based on Poverty Indicators in East Java in 2020 ABSTRACTThe existence of the pandemic COVID-19 in Indonesia has resulted in higher poverty in Indonesia, especially in East Java, which is one of the other provinces with high cases in Indonesia. The purpose of this study is to find out the grouping of regencies/cities in East Java that have similar characteristics based on the poverty indicators in 2020. This study uses data obtained from the Badan Pusat Statistik. The method used is k-medoids clustering method which is a clustering partition method for grouping n objects into k clusters. Based on the results of the study, it was found that the grouping of the characteristics of each cluster formed based on the value of the poverty indicator in East Java in 2020 was 2 clusters. Where 30 regencies/cities in cluster 1 and and 8 regencies/cities in cluster 2. Cluster 1 has the characteristics of the percentage of households that have proper sanitation, life expectancy, and a high percentage of literacy rates aged 15-55 years. While cluster 2 has the characteristics of the percentage of poor households receiving Raskin, the percentage of poor people, and the percentage of per capita expenditure on food with high poor status.Keywords: Clustering; East Java; K-Medoids; poverty
Efek Hepatoprotektor Ekstrak Etanol Batang Bajakah Tampala (Spatholobus Littoralis Hassk) pada Tikus yang Diinduksi Isoniazid Dhimas Adhityasmara; Dewi Ramonah
JURNAL ILMIAH SAINS Volume 22 Nomor 1, April 2022
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (676.449 KB) | DOI: 10.35799/jis.v22i1.36293

Abstract

Tujuan penelitian ini yaitu untuk mengetahui pengaruh pemberian dan dosis efektif ekstrak etanol batang bajakah terhadap penurunan SGOT & SGPT tikus putih jantan galur Wistar yang diinduksi isoniazid. Penelitian ini merupakan jenis penelitian eksperimental, dengan obyek penelitian penurunan kadar SGPT & SGOT setelah diberikan senyawa uji selama 14 hari. Dosis sediaan ekstrak etanol batang bajakah yang digunakan adalah dosis 200, 300 dan 400 mg/kgBB. Kontrol positif  digunakan   silymarin   dosis   5 mg/200gBB.  Sebagai  penginduksi  digunakan isoniazid  dosis 350 mg/KgBB  yang diberikan 14 hari sebelum perlakuan senyawa uji. Kelompok  normal  tanpa  diberi  perlakuan  untuk  mengetahui  pengaruh  lingkungan  terhadap hewan uji. Hasil penelitian menunjukan ekstrak etanol batang bajakah tampala memiliki efek hepatoprotektor pada tikus jantan yang dinduksi isoniazid 350mg/kgBB selama 14 hari. Dosis efektif ekstrak etanol batang bajakah sebagai hepatoprotektor adalah 200 mg/kgBB.Kata kunci: Bajakah tampala; hepatoprotektor; isoniazidHepatoprotector Effects of Bajakah Tampala Stem Ethanol Extract (Spatholobus Littoralis Hassk) on Isoniazid Induced RatsABSTRACTThe purpose of this study was to determine the effect of administration and effective dose of ethanol extract of bajakah stems on the reduction of SGOT & SGPT of isoniazid-induced male white rats of Wistar strain. This research is an experimental type of research, with the object of research decreasing levels of SGPT & SGOT after being given the test compound for 14 days. The dosages of the ethanol extract of the bajakah stem used were doses of 200, 300 and 400 mg/kgBW. The positive control used silymarin at a dose of 5 mg/200gBW. As an inducer, isoniazid at a dose of 350 mg/KgBW was used 14 days before the treatment of the test compound. The normal group without treatment was to determine the effect of the environment on the test animals. The results showed that the ethanol extract of Bajakah tampala rods had a hepatoprotective effect on male rats induced by isoniazid 350mg/kgBW for 14 days. The effective dose of ethanol extract of bajakah stem as a hepatoprotector was 200 mg/kgBW.Keywords: Bajakah tampala; hepatoprotector; isoniazid
Indeks Pencemaran Lingkungan Sungai Wangi, Desa Beujeng, Kecamatan Beji, Kabupaten Pasuruan, Jawa Timur Moh. Awaludin Adam; Ach Khumaidi; Ramli Ramli; Yenny Risjani; Agoes Soegianto
JURNAL ILMIAH SAINS Volume 22 Nomor 1, April 2022
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (753.99 KB) | DOI: 10.35799/jis.v22i1.36791

Abstract

Banyaknya limbah cair yang terbuang ke aliran Sungai Wangi memberikan potensi pencemaran. Pencemaran berasal dari limbah pabrik yang sudah berlangsung sejak tahun 2015. Tujuan dari penelitian yaitu untuk melakukan analisis kualitas lingkungan Sungai Wangi dan menentukan indeks pencemarannya. Metode penelitian dilakukan dengan metode survey dan Pengambilan sampel air sungai dilakukan di sekitar aliran sungai Wangi, Desa Beujeng, Kecamatan Beji, Kabupaten Pasuruan. Pengambilan sampel dilakukan pada 3 (tiga) area yaitu area industri, area pemukimam dan area pertanian. Penelitian dilakukan pada bulan Juni 2020 sampai dengan bulan Juli 2021. Hasil penelelitian menunjukkan adanya kontaminasi logam berat pada Sungai Wangi yang mengandung Pb, Cd dan Hg.  Kadar Pb, Cd dan Hg pada perairan rata-rata sebesar 0,031 ppm, 0,019 dan 0,009 ppm. Nilai tersebut sudah melampaui standar baku mutu PP 22/2021 kelas 3 yang diperbolehkan untuk aliran sungai. Sedangkan beberapa data parameter kualitas air lainnya dianalisis dengan menggunakan metode pollution index (PI). Metode ini digunakan untuk menentukan indeks pencemaran. Jumlah indeks pencemaran rata-rata (PIrata-rata)  pada Sungai Wangi secara umum (area industri, pemukiman dan pertanian) adalah = 5,503. Indeks pencemaran ini menunjukkan kondisi Sungai Wangi termasuk pada klasifikasi “cemar sedang”.Kata kunci: Indeks pencemaran; logam berat; sungai wangiEnvironmental Pollution Index of the Wangi River, Beujeng Village, Beji District, Pasuruan Regency, East Java ABSTRACTThe amount of liquid waste that is wasted into the Wangi River stream provides the potential for pollution. Pollution comes from factory waste that has been going on since 2015. The purpose of this research is to analyze the environmental quality of the Wangi River and determine its pollution index. The research method was carried out by survey methods and river water sampling was carried out around the Wangi river flow, Beujeng Village, Beji District, Pasuruan Regency. Sampling was carried out in 3 (three) areas, namely industrial areas, residential areas and agricultural areas. The study was conducted from June 2020 to July 2021. The results showed heavy metal contamination in the Wangi River containing Pb, Cd and Hg. The average levels of Pb, Cd and Hg in the waters were 0.031 ppm, 0.019 and 0.009 ppm. This value has exceeded the PP 22/2021 class 3 quality standard which is allowed for river flow. Meanwhile, several other water quality parameter data were analyzed using the pollution index (PI) method. This method is used to determine the pollution index. The number of the average pollution index (PI average) on the Wangi River in general (industrial, residential and agricultural areas) is = 5.503. This pollution index shows the condition of the Wangi River is included in the "medium polluted" classification.Keywords: Heavy metals; pollution index; wangi river

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