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Jurnal Natural
Published by Universitas Syiah Kuala
ISSN : 14118513     EISSN : 25414062     DOI : https://doi.org/10.24815/jn
Core Subject : Science, Agriculture,
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Energy Immunology & microbiology Neuroscience Physics
Jurnal Natural (JN) aims to publish original research results and reviews on sciences and mathematics. Jurnal Natural (JN) encompasses a broad range of research topics in chemistry, pharmacy, biology, physics, mathematics, statistics, informatic and electronic.
Arjuna Subject : Matematika - Matematika (Lain-Lain)
Articles 7 Documents
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Search results for , issue "Volume 24 Number 3, October 2024" : 7 Documents clear
Vegetation composition and carbon stocks in West Batang Toru Forest Block, North Sumatra PASARIBU, NURSAHARA; RANGKUTI, LATIFAH HANNUM; SIREGAR, JULIUS PAOLO
Jurnal Natural Volume 24 Number 3, October 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v24i3.30908

Abstract

West Batang Toru Forest Block, North Tapanuli Regency, North Sumatra Province is a forest that contains numerous species of tree stands and is estimated to be able to store a considerable high carbon from the atmosphere. The aim of this study was to determine the composition of vegetation and the potential for carbon stored in the forest region. This research was conducted from September 2021 to March 2022 using a purposive sampling method. Vegetation data were analyzed using the Diversity Index (H'), Uniformity Index (E) using the Shannon-Wiener equation. The carbon stock of each stand per species was estimated using the Ketterings allometric equation. The study documented a total of 64 families, belonging to 297 species with a total of 2,399 individuals. The percentage of composition of all growth rates ranged from 31%-59%. The Importance Value Index (IVI) of all growth rates ranged between 14.3 to 71.7%. The highest diversity index and evenness index at the tree level were 4.71 and 0.85. The stored carbon is 373.227 tons C/ha in West Batang Toru Forest Block, highlighting the forest region as an important green carbon sink.
Study of mathematical models of type 2 diabetes mellitus and its complications MAGHFIRAH, AFIATUN; GANI, BASRI A.; RAMLI, MARWAN; IKHWAN, MUHAMMAD
Jurnal Natural Volume 24 Number 3, October 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v24i3.33482

Abstract

The rapid increase in type 2 diabetes mellitus (DM) cases in Indonesia, driven by hereditary factors and unhealthy lifestyles, poses significant health challenges. This study develops a compartmental model to analyze the progression of type 2 DM and the onset of complications, classifying individuals into susceptible, patients without complications, patients with complications, and those disabled due to complications. The model examines the influence of two key factors on the recovery from complications: habitual factors, including medication adherence, physical activity, dietary habits, smoking history, and environmental factors, such as stress levels, environmental support, patient trust, and compliance. The results indicate that habitual factors have a more substantial impact on mitigating complications compared to environmental factors, suggesting that lifestyle interventions are crucial in improving patient outcomes. The model also shows that an increase in behavioral interactions leading to disease progression results in instability, emphasizing the need for early and consistent behavioral interventions. This research offers valuable insights for healthcare providers and policymakers. By identifying the most influential factors in managing complications, the model can guide the development of targeted interventions that prioritize habitual changes, such as medication adherence and physical activity. Public health strategies can be tailored to emphasize the importance of these habitual factors, potentially reducing the burden of type 2 DM complications. Overall, this study highlights the critical role of personalized, behavior-focused interventions in the management and prevention of complications in patients with type 2 DM, offering a practical framework for improving patient care.
Genetic diversity of local sweet potato cultivars (Ipomoea batatas [L.] Lam.) from Bulungan, North Kalimantan based on morphological characters OKTAVIANINGSIH, LINDA; FITRIANI, FITRIANI; HENDRA, MEDI; ARIF, MUHAMMAD FAUZI
Jurnal Natural Volume 24 Number 3, October 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v24i3.40568

Abstract

Indonesia is one of the centers of sweet potato diversity worldwide. Sweet potatoes have the potential to be developed for food consumption. This research aims to determine the diversity of sweet potato cultivars, their morphological characteristics, and the relationships between local sweet potato cultivars in Bulungan Regency, North Kalimantan. The local sweet potato cultivars were selected using purposive sampling with the exploration method. The morphological characterization of the samples is based on IBPGR (International Board for Plant Genetic Resources) standards. Cluster analysis was conducted to identify the relationships using MVSP software version 3.1. The research identified 27 local sweet potato cultivars in Bulungan Regency. Morphological characterization revealed 41 characters that can differentiate each local sweet potato cultivar. The most influential characteristics include leaf shape, flower surface texture, the position of the stigma, flower surface color, back petal color, center shape and the number of lobes, primary leaf vein color, lobe type, main leaf bone color, stem internode length, and plant type. A flower shape that had not been discovered before, a pentagonal shape with curves, was identified. Cluster analysis divided the cultivars into two major groups with a coefficient range of 0.593 to 0.888 (59.3 to 88.8%). Cluster A consisted of one member, LK-7 (purple sweet potato), while Cluster B consisted of several subgroups with 26 local cultivars. The people of Bulungan Regency use these local cultivars for food, animal feed, and medicinal purposes.
Green tea (Camellia sinensis L.) potential to liver of hyperuricemia rats (Rattus norvegicus) fed with high purine diet NUGRAHENI, PUTRANTY WIDHA; MAHDI, CHANIF; RAHMAWATI, FITRIA; ANALITA, RIZKI NUR
Jurnal Natural Volume 24 Number 3, October 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v24i3.29599

Abstract

Uric acid is produced in tissues containing xanthine oxidases, like the small intestine and liver, as involved in the purine metabolism of adenine and guanine. High uric acid levels cause damage to cell membranes due to the lipid peroxidase chain reaction. Foods containing high purines will activate the xanthine oxidase (XOD), causing an increase in free radicals. Free radicals attack polyunsaturated fatty acids (PUFA) by forming lipid peroxides. PUFA molecules contain multiple double bonds, which make them susceptible to oxidation by reactive oxygen species (ROS), such as free radicals. PUFA will be broken into simple compounds such as pentane, ethane, and aldehydes, leading to malondialdehyde (MDA) formation. High MDA levels illustrate the process of cell membrane oxidation leading to cell membrane damage. Hyperuricemia is often treated using synthetic drugs such as allopurinol; however, it can cause side effects. Some people will choose medicinal plants with minimal side effects. Green tea (Camellia sinensis L.) contains many polyphenol antioxidants, especially flavonoids, which also have a strong antioxidant effect by exerting multiple mechanisms such as inhibiting several enzymes, including antiphospholipid peroxidase, free radical scavengers, metal bonds, and xanthine oxidase (XOD). Statistical analysis results proved that green tea with a dose of 600 mg/kg BW could decrease the level of MDA in the liver by 84.87% (p 0.01) and reduce the activity of XOD by 35.36% (p 0.01). Taken together, green tea can improve liver histopathology.
Multi-drug resistance-1 (MDR-1) gene expression in MCF-7 cells after treated with doxorubicin-deoxyelephantopin combination and prediction of inhibitory activity against Pgp receptors with in silico DANIEL, DANIEL; FRENGKI, FRENGKI; JALALUDDIN, MUHAMMAD; SARI, WAHYU EKA; ROSMAIDAR, ROSMAIDAR; HASRIATI, HASRIATI; ZAKIAH, NONI
Jurnal Natural Volume 24 Number 3, October 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v24i3.33237

Abstract

Doxorubicin chemotherapy has been a strong focus in breast cancer research. Side effects, toxicity and resistance have been extensively studied. One proposed solution to these issues that its combination with deoxyelephantopin. Deoxyelephantopin is known to be toxic in many cancer cells but safe in normal cells. IC50 of each compound were determined by using a MTT assay, and the MDR-1 gene mRNA expression were determined by using qPCR method, while the interaction of doxorubicin in combination with deoxyelephantonin on Pgp receptor were predicted by using an in silico approach. The IC50 of deoxyelephantopin was found to be 11.2 g/mL, while IC50 of doxorubicin was 448 nM IC50 values showed a deoxyelephantopin-doxorubicin combination was able to reduce MDR-1 expression by 19% compared to doxorubicin and IC50 values indicated that the combination formula reduced the expression by 15% over doxorubicin alone. The affinity of doxorubicin and deoxyelephantopin is -12.16 kcal/mol and -9.51 kcal/mol, respectively, while the affinity of doxorubicin after combine with deoxyelephantopin decreases from -12,16 kcal/mol to -11,25 kcal/mol due to the release of one Leu 221 hydrogen bond. The combination of doxorubicin with deoxyelephantopin is able to reduce expression and suppress the function of the Pgp protein.
Diversity of butterflies (Lepidoptera: Papilionoidea) in Universitas Samudra, Langsa SALWA, ZAKIYAH HANIFAH; SARI, HERLINA PUTRI ENDAH; PUTRI, KARTIKA APRILIA
Jurnal Natural Volume 24 Number 3, October 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v24i3.39359

Abstract

Butterflies are one of the animals that have an important role in human life which is currently recorded totaling around 19,022 species in the world and 1,900 species found in Indonesia. Research on butterflies in the campus area in Aceh has not been done too much, so there is a need for research on butterfly diversity in the campus area, especially in Langsa, Aceh. The purpose of this study was to record the species and to analyze ecological factor of butterflies at Universitas Samudra. Sampling was conducted for 5 times once a week from December 2023-January 2024 by purposive random sampling using sweeping techniques and exploring method in 5 observation locations. The results found 30 species from 5 families with a total of 413 individuals. The most common family is family Nymphalidae as many as 15 species (50%) and the most common species found was Appias olferna with a total of 56 individuals. The data found were analyzed for ecological assessment. The result showed the diversity index with H' value of 2.17-2.82 classified as a medium, an evenness index with E value of 0.87-0.94 classified as high, and a dominance index with D value of 0.07-0.19 classified as low.
On locating-chromatic number of helm graph H_m FOR 10m28 WELYYANTI, DES; SUTANTO, DASA; YULIANTI, LYRA
Jurnal Natural Volume 24 Number 3, October 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v24i3.33190

Abstract

Let G = (V,E) be a connected graph and c be a k-coloring of G. The color class S_i of G is a set of vertices given color i, for 1 i k. Let = {S_1,S_2,,S_k} be an ordered partition of V(G). The color code of a vertex v $in$ (element) V(G) is defined as the ordered k--tuplec_ (v)=(d(v,S_1),d(v,S_2),...,d(v,S_k)),where d(v,S_i) = min{d(v,x)| x $in$ (element) S_i} for 1 i k. If distinct vertices have distinct color codes, then c is called a locating-coloring of G. The locating-chromatic number _L (G) is the minimum number of colors in a locating-coloring of G. This paper discusses the locating-chromatic number of helm graph H_m for 10 m 28. Helm graph H_m is constructed by adding some leaves to the corresponding vertices of wheels W_m, for m 3.

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