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Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran
Published by Lembaga Pengembangan Kinerja Dosen
ISSN : 29649668     EISSN : 29649676     DOI : 10.55606
Core Subject : Health,
Dentistry Health Professions Public Health
akademisi dan praktisi serta mahasiswa kesehatan yang ingin mendapatkan artikel dalam Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 391 Documents
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Comparative Effectiveness and Safety of Lemborexant Versus Benzodiazepines in Patients with Insomnia: A Systematic Review and Meta-Analysis Kartini Hasballah; Fifin Oktaviani; Heldi Candra; Wilda Fasim Hasibuan
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 3 (2026): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i3.6976

Abstract

Chronic insomnia is a common sleep disorder that erodes quality of life, cognitive performance, and day-to-day safety. Benzodiazepines remain a mainstay of pharmacological treatment, yet their safety profile is a persistent concern, especially among older adults. Lemborexant, a newer dual orexin receptor antagonist, offers a distinct mechanism and a claim of improved safety. This review set out to weigh the two agents against each other on effectiveness and safety, focusing on daytime somnolence, fall risk, and cognitive impairment. A systematic review and meta-analysis was performed in line with the PRISMA 2020 guideline. Five databases (PubMed/MEDLINE, Scopus, EMBASE, the Cochrane Library, and ScienceDirect) were searched up to April 2026. Randomised controlled trials and comparative observational studies contrasting lemborexant with benzodiazepines or placebo in adults with insomnia were eligible. Risk of bias was appraised with the Cochrane RoB 2.0 tool and the Newcastle-Ottawa Scale. From 747 records, 18 studies entered the qualitative synthesis and 12 the quantitative analysis (n = 49,907 participants). Compared with benzodiazepines, lemborexant produced less daytime somnolence (SMD = -0.34; 95% CI: -0.52 to -0.16; p < 0.001), a lower risk of falls (log OR = -0.51; 95% CI: -0.72 to -0.30; p < 0.001), and less cognitive impairment (SMD = -0.18; 95% CI: -0.34 to -0.02; p = 0.028). Between-study heterogeneity was moderate (I² = 38-51%). Lemborexant shows a more favourable safety profile than benzodiazepines for daytime somnolence, falls, and cognition, particularly in older adults. The findings support considering lemborexant as a first-line pharmacological option for chronic insomnia when non-pharmacological therapy is unavailable or inadequate.
Efektivitas Proprioceptive Neuromuscular Facilitation (PNF) dalam Meningkatkan Keseimbangan Dinamis pada Anak Atlet Sepak Bola Penyandang Down Syndrome Cici Resti Pangestuti; Deasy Virka Sari; Swanny Trikadjanti Widyaatmaja
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 3 (2026): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i3.6988

Abstract

Down Syndrome is a condition caused by a change in genes that leads to problems with movement skills, weak muscles, difficulty with coordination, and trouble keeping balance while moving. This condition can make it harder for a child to take part in sports, especially soccer, which needs good balance and posture control. Proprioceptive Neuromuscular Facilitation, or PNF, is a type of physical therapy that helps improve control of muscles and balance by using sensory stimulation from within the body. The goal of this study is to show how PNF can help improve dynamic balance in child soccer players who have Down Syndrome. The study used the Proprioceptive Neuromuscular Facilitation (PNF) method. The study included 40 participants who were chosen through purposive sampling according to specific rules for who could and could not take part. During the study, PNF exercises were provided once a week as the intervention. The Y Balance Test was used to measure dynamic balance both before and after the intervention. Data analysis was done using a Paired Sample t-test both by looking at each variable alone and comparing pairs of variables, after making sure the data followed a normal distribution as checked by the Shapiro-Wilk test. Results: The average dynamic balance score went up from 72.497 before the test to 83.662 after the test. The statistical analysis results showed a big difference between the situation before and after the intervention, with a significance value of p.
Hubungan Pengetahuan dan Sikap Wanita Usia Subur tentang Kondisi Layak Hamil Lellyawaty Lellyawaty; Merlin Karinda
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 3 (2026): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i3.7005

Abstract

Background: Women of reproductive age (WRA), aged 15–49 years, require adequate physical preparation and knowledge before pregnancy. Pregnancy eligibility includes physical and mental health, good nutritional status, and the absence of conditions that may adversely affect pregnancy and the fetus. Objective: To determine the relationship between knowledge and attitudes among WRA and pregnancy eligibility. Methods: This quantitative study used a cross-sectional design involving 41 WRA in the Banjarmasin Indah Public Health Center working area who attended Tunjung Biru Integrated Health Post. Respondents were selected through purposive sampling, and data were collected using a questionnaire. Results: Among respondents who were not eligible for pregnancy, 36.6% had positive attitudes and 39.1% had good knowledge. Among those eligible for pregnancy, 31.7% had positive attitudes and 34.0% had good knowledge. As more than 20% of cells had an expected count below five, Fisher’s exact test was used. A p-value > 0.05 indicated no significant relationship between knowledge or attitudes and pregnancy eligibility. Conclusion: Good knowledge and positive attitudes do not necessarily determine pregnancy eligibility, which may also be influenced by age, nutritional status, anemia, parity, birth spacing, and comorbidities. Integrated preconception education and screening are therefore needed to support healthy pregnancy preparation.
Aktivitas Imunomodulator Kulit Buah Durian (Durio zibethinus Murr) Varietas Rajagaluh Terhadap Fagositosis Sel Makrofag Pada Staphylococcus aureus ATCC 25913 di Mencit Balb/C (Mus musculus) Fahrisha Viratika Rusmanda; Amanah Amanah; Dadan Ramadhan A
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 4 (2026): Oktober: Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i4.7008

Abstract

Staphylococcus aureus is a major cause of nosocomial infections. Natural imunomodulatory agents are needed to strengthen immune responses. The Rajagaluh variety of durian peel contains flavonoids, saponins, tannins, triterpenoids, and alkaloids, which are potential imunomodulators. To analyze the imunomodulatory activity of durian peel extract on macrophage phagocytosis in S. aureus-infected Balb/C mice and determine the most effective dose. This experimental study used a post-test only control group design involving 30 male Balb/C mice divided into six groups (negative control, positive control, normal control, and three treatment groups receiving 200, 400, and 800 mg/kgBW of extract). The extract was administered orally, followed by S. aureus induction. Peritoneal fluid was collected to assess macrophage phagocytic activity. A significant increase in macrophage phagocytosis was observed in the 800 mg/kgBW treatment group, comparable to the standard immunostimulant Phyllanthus. Rajagaluh durian fruit leather has flavonoids, saponins, and tannins that play an active role. Durian fruit peel extract of the Rajagaluh variety demonstrates imunomodulatory activity by enhancing macrophage phagocytosis against Staphylococcus aureus. The most effective dose was 800 mg/kg BB.
Hubungan Indeks Massa Tubuh dengan Kadar Kalsium dalam Serum Darah pada Pasien Osteoartritis Genu di Posyandu Larasati, Dukuh Kupang, Surabaya Cantika Nuzulia Rahmayanti; Ayly Soekanto; Handy Arief; I Made Subhawa Harsa
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 4 (2026): Oktober: Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i4.7009

Abstract

Osteoarthritis genu is a degenerative joint disease influenced by mechanical and metabolic factors. A high body mass index (BMI) increases intra-articular loading, whereas serum calcium reflects mineral homeostasis related to bone health. To analyze the association between BMI and serum calcium levels among patients with osteoarthritis genu at Larasati Posyandu, Dukuh Kupang, Surabaya. This analytic observational study used a cross-sectional design and was conducted in January 2026 among 30 female respondents aged 35-75 years who were diagnosed with osteoarthritis genu and selected through purposive sampling. BMI was calculated from measured body weight and height, while serum calcium was measured using spectrophotometry. The Shapiro-Wilk normality test was followed by Pearson correlation analysis. Most respondents were aged 46-57 years (53.3%). The most frequent BMI categories were overweight and obesity, each comprising 10 respondents (33.3%). All respondents had normal serum calcium levels (8.5-10.5 mg/dL). Pearson analysis showed a weak, non-significant negative correlation between BMI and serum calcium (r = -0.250; p = 0.183). There was no significant association between BMI and serum calcium levels among patients with osteoarthritis genu. BMI monitoring remains important as a mechanical risk indicator, whereas a single serum calcium measurement should not be used as a standalone marker of osteoarthritis genu.
Ocular Syphilis: Diagnostic Challenges and Current Management Strategies Luh Putu Indah Wahyuningtyas; I Dewa Agung Gede Agastya Janardhana
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 4 (2026): Oktober: Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i4.7015

Abstract

Ocular syphilis is an important and potentially sight-threatening manifestation of T. pallidum infection, capable of occurring at any stage of the disease. Known as “The Great Imitator,” it presents with highly variable and non-specific clinical features that frequently resemble autoimmune or other infectious ocular conditions, leading to delayed diagnosis and potential mismanagement. The pathophysiology involves early hematogenous dissemination, endothelial injury, and immune-mediated inflammation, often overlapping with mechanisms seen in neurosyphilis. Ocular involvement may affect virtually all eye structures, with uveitis being the most common presentation, alongside manifestations such as retinitis, vasculitis, optic neuritis, and interstitial keratitis. Diagnosis is made through an increased index of clinical suspicion, based on the results of treponemal and nontreponemal tests. Imaging studies like optical coherence tomography and fluorescein angiography help assess the condition but are not definitive. Management follows neurosyphilis treatment protocols, with intravenous penicillin as the cornerstone of therapy and adjunctive corticosteroids or immunosuppressive agents in selected cases. Given the global resurgence of syphilis and increasing reports of ocular involvement, early recognition and prompt treatment are essential to prevent irreversible visual impairment.
Hubungan Skor CURB-65 dengan Lama Rawat Inap pada Pneumonia Komunitas Dewasa Dengan Terapi Levofloksasin di Rumah Sakit Daerah Gunung Jati Cirebon Marvela Fayza Nafiatha; Adetya Rahma Dinni; Emallia Fitriani
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 4 (2026): Oktober: Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i4.7017

Abstract

Adult community-acquired pneumonia (CAP) contributes substantially to hospital admissions, especially among elderly and comorbid patients. Indonesia's PDPI guideline reports CAP incidence rising from 6 to 34 per 1,000 population between ages 18-39 and >75 years, with inpatient mortality of 5-20%. Levofloxacin is widely used empirically for its broad spectrum and rapid clinical improvement, yet local data on hospital stay and therapy duration remain limited. To describe hospital stay and levofloxacin duration by sex, age, CURB-65 score, and comorbidities, and their correlation among adult CAP patients at Gunung Jati Regional Hospital, Cirebon, 2025. Retrospective descriptive study using medical records, total sampling, and Spearman's correlation test. Of 55 patients, most were male (58.2%; consistent with Fésüs et al., 57.7%) and aged 45–64 years (47.3%). Leading comorbidities were cardiovascular disease (20.0%) and diabetes mellitus (14.5%). CURB-65 scores were mostly low-moderate (41.8% and 40.0%). Hospital stay and intravenous therapy were both most commonly 3–5 days (56.4% and 98.2%). CURB-65 correlated significantly but weakly with length of stay (r=0.290; p=0.032). Patients were predominantly middle-aged to older males with mild-to-moderate severity, hospitalized 3-5 days, and higher CURB-65 scores were linked to longer stays.
Pengaruh Edukasi Visual melalui Media Flipchart terhadap Tingkat Pengetahuan dan Minat Pemakaian KB Implan pada Wanita Usia Subur di Wilayah Kerja Puskesmas Purwokerto Timur II Yulia Nurseli; Ikhwah Mu’minah; Ima Syamrotul Muflihah; Isnaeni Rofiqooh
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 4 (2026): Oktober: Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i4.7042

Abstract

Implant contraception is an effective long-term method; however, its utilization coverage at Purwokerto Timur II Public Health Center remains low, accounting for only 8% in 2024. This low acceptance is attributed to a lack of knowledge and interest among women of reproductive age (WRA). Flipchart-based media are considered effective for delivering information innovatively by combining visual and verbal elements, making materials easier to understand and remember. This study aimed to determine the effect of visual education through flipchart media on the level of knowledge and interest in implant contraceptive use among WRA in the working area of Purwokerto Timur II Public Health Center. This study employed a quasi-experimental design with a control group pretest-posttest. A total of 66 respondents were selected using purposive sampling. The independent variable was the flipchart media, while the dependent variables were the knowledge level and interest among WRA. Data were collected using valid and reliable questionnaires and analyzed using the Wilcoxon Signed-Rank Test (α < 0.05). The results showed an increase in knowledge and interest after the intervention. The majority of WRA initially had a moderate knowledge level (75.8%), which increased to a good level (93.9%), while moderate interest (51.5%) increased to high interest (84.8%). The statistical analysis yielded a p-value of 0.000. In conclusion, visual education through flipchart media has a significant effect on the level of knowledge and interest in implant contraceptive use among women of reproductive age in the Purwokerto Timur II Public Health Center area.
Gambaran Karakteristik Pasien Hordeolum Berdasarkan Usia, Jenis Kelamin, dan Lokasi Anatomis di RSUD Waled Tahun 2024-2025 Fildzah Ayudya Ellyzar; Widi Astuti; Boyke Sisprihattono
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 4 (2026): Oktober: Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i4.7048

Abstract

Hordeolum is an acute infection of the eyelid glands characterized by pain, hyperemia, and localized edema. A preliminary survey at Waled Regional General Hospital in 2024–2025 identified 146 patients with hordeolum. Aim: To describe the characteristics of patients with hordeolum based on age, sex, and location. Methods: This study used a descriptive observational design with a retrospective approach. Secondary data were obtained from the medical records of patients with hordeolum at the Eye Clinic of Waled Regional General Hospital from January 2024 to December 2025. Samples were selected based on the inclusion and exclusion criteria, resulting in 58 patients. Data were analyzed univariately and presented as frequency distributions and percentages. Results: Most patients with hordeolum were adults aged 18–59 years, accounting for 67.2% of the total sample. Based on sex, female patients were more common than male patients, accounting for 58.6% and 41.4%, respectively. Based on anatomical location, hordeolum was most frequently found in the upper eyelid at 62.1%, followed by the lower eyelid at 32.8%, while involvement of both eyelids was found in 5.2% of patients. Conclusion: The characteristics of patients with hordeolum at Waled Regional General Hospital during 2024–2025 were predominantly adults, female, and most commonly affected in the upper eyelid. These findings are expected to provide baseline data for evaluating eye health services, supporting promotive and preventive efforts through eyelid hygiene education, and serving as a reference for further studies on the risk factors and characteristics of hordeolum.
Hubungan Riwayat Merokok dan Indeks Massa Tubuh terhadap Kejadian Alopesia Androgenetik pada Pria di Kampung Melayu Tahun 2026 Sudarsono Sudarsono; Kasih Purwati; Fazira Ayumi
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 4 (2026): Oktober: Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i4.7053

Abstract

. Androgenetic alopecia (AGA) is a common form of hair loss in men that can be influenced by lifestyle and metabolic factors. Smoking and increased body mass index (BMI) are suspected to be associated with the occurrence of AGA, yet research findings regarding this relationship remain inconsistent. This study aimed to determine the association between smoking history, BMI, and the occurrence of AGA among adult men in Kampung Melayu. This was an analytical observational study with a cross-sectional design involving 96 men aged 30–50 years, selected using multistage cluster random sampling. AGA was assessed using the Hamilton-Norwood Scale, while smoking history was obtained via questionnaire, and BMI was calculated based on weight and height measurements. Data analysis employed Fisher's Exact Test for smoking history and the Chi-Square test for BMI, with α = 0.05. A total of 79 respondents (82.3%) had AGA, 79 respondents (82.3%) had a history of smoking, and 66 respondents (68.8%) fell into the overweight to obesity class II BMI categories. No association was found between smoking history and AGA (p = 0.493), whereas a significant association was found between BMI and AGA (p = 0.001)

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