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INDONESIA
Eduvest - Journal of Universal Studies
Published by Green Publisher Indonesia
ISSN : 27753735     EISSN : 27753727     DOI : 10.36418
Core Subject : Health, Science, Social, Engineering,
Aerospace Engineering Computer Science & IT Health Professions Neuroscience Social Sciences
Eduvest - Journal of Universal Studies is a double blind peer-reviewed academic journal and open access to multidiciplinary fields. The journal is published monthly by Green Publisher Indonesia. Eduvest - Journal of Universal Studies provides a means for sustained discussion of relevant issues that fall within the focus and scopes of the journal which can be examined empirically. This journal publishes research articles multidisciplinary sciences, which includes: Humanities and social sciences, contemporary political science, Educational sciences, religious sciences and philosophy, economics, Engineering sciences, Health sciences, medical sciences, design arts sciences and media. Published articles are from critical and comprehensive research, studies or scientific studies on important and current issues or reviews of scientific books.
Arjuna Subject : Bisnis, Menejemen, dan Akutansi (semua kategori) - Bisnis, Menejemen, dan Akutansi (Lain-Lain)
Articles 2,617 Documents
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Challenges of Monitoring Blood Levels of Bedaquiline in Drug-Resistant Tuberculosis: A Narrative Review Isra, Nur; Sari, Santi Purna; Harahap, Yahdiana; Handayani, Raden Rara Diah
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.50267

Abstract

Bedaquiline, a second-line drug for drug-resistant tuberculosis (MDR-TB), is one of the latest generation drugs in the treatment of tuberculosis (TB). However, the challenge in determining the optimal dose and individual pharmacokinetic variability requires the implementation of Therapeutic Drug Monitoring (TDM). This article aims to evaluate the challenges of TDM bedaquiline through a narrative review of the current literature. Relevant articles were identified through computerized searches on PubMed and Google Scholar using a combination of keywords related to bedaquiline, pharmacokinetics, and TDM. Limited clinical data indicate a lack of standard exposure targets and reliable efficacy thresholds. Pharmacokinetic variability is influenced by factors such as age, weight, gender, genetics, comorbidities, and serum albumin. Technical challenges include the need for precise analytical methods and the accessibility of technology in clinical practice. The use of TDM for bedaquiline offers the potential to improve the efficacy of MDR-TB treatment, but more research is needed to address pharmacokinetic variability and develop standardized guidelines.
Profile of Drug-Resistant Tuberculosis Patients at Rumah Sakit Universitas Indonesia Depok Period October 2024 Dumiarsih, Suci Rizki; Sari, Santi Purna; Andrajati, Retnosari; Handayani, Diah
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.50269

Abstract

Indonesia has been one of the three countries in Asia that contributes to the highest case of Tuberculosis (TB) in the world. Tuberculosis itself counted as the top ten cause of death globally. Two of the challenges in controlling TB cases are the occurrence of drug-resistance strain and patients’ adherence. Drug-resistant TB has to be treated with the second line drugs of TB with higher risk of adverse events. Linezolid as one of the suggested drugs by WHO in the treatment may increase patients’ risk of cytopenia events. This study was conducted to represent the profile of drug-resistant TB obtained from Rumah Sakit Universitas Indonesia (RSUI) Depok period October 2024. Design of this study is a quantitative-descriptive where the data of patients obtained from the patients’ medical records in the period of October 2024. The findings of this study showed the total number of drug-resistant TB was 104 with 3 cases of HIV and 70 patients having Linezolid in their regimen. Most of the patients are male with mean of age 41.3 years. New cases and RR/MDR TB level are dominated while on the other hand there’s 9 cases of After Failure and 4 others are After Loss to Follow-up. Median values obtained for patients’ leukocytes, hemoglobin, and platelets are 7818.0, 11.9, 279.5 respectively.
Overview of Antibiotic Prescribing Based on Aware Category at Fatmawati Hospital in the Period of May 2024 - November 2024 N, Panggabean Sylvia; Retnosari, Retnosari; Subhan, Subhan; Latuperissa, Debby
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.50291

Abstract

WHO issued AWaRe guidelines to optimize the use of antibiotics to prevent resistance. This guideline is also used in Indonesia, including hospitals. Fatmawati is one of the government hospitals in DKI Jakarta that has the most patient visits. To describe the prescribing of antibiotics in hospitals. Fatmawati based on the AwaRe category. The design of this study uses a qualitative description with a total sampling method and then analyzed using Microsoft Excel. The most prescribing of antibiotics at Fatmawati Hospital as many as 86,833 were in the watch (61.5%), access (30.7%) and last reserve (7.8%) categories. The most prescribed antibiotics in the access group are metronidazole (25.655%), ampicillin (20.835%), gentamicin (12.273%) with the most prescribed dosage forms being tablets (35.064%), sterile powder (30.123%), infusion (22.154%). In the watch group, the most prescribed are ceftriaxone (26.887%), cefixime (22.363%), levoflosacin (17.492%) with the most prescribed dosage forms being sterile powder (47.992%), capsules (21.463%), infusions (14.232%). In the reserve group, the most prescribed are meropenem (62.405%), cefepime (8.705%), ampiscillin/sulbactam (7.919%) with the most prescribed dosage forms being sterile powder (90.93%), tablets (5.695%), and infusions (4.197%). The results showed that the most antibiotic prescriptions were in the watch group compared to the access category. These findings show that it is necessary to re-evaluate PPAB at the hospital. Fatmawati
Evaluation of Open Defecation Free (ODF) Policy in Pangandaran Regency in 2024 Anisah, Anisah; Aji, Budi; Diyaning Intiasari, Arih
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.50800

Abstract

Proper sanitation is a crucial factor in creating a healthy environment and supporting the achievement of the Sustainable Development Goals (SDGs), particularly the Open Defecation Free (ODF) target (Bappenas, 2023). Pangandaran Regency achieved 100% ODF status in 2023, but monitoring one year later revealed that Harumandala and Kertajaya Villages experienced setbacks, with some residents returning to open defecation practices. This study employs a qualitative approach with a case study method, involving ten competent informants. The findings indicate that although sanitarians have received STBM training, the implementation of triggering activities is hindered by a lack of human resources, limited funding from ADD and BOK, and inadequate understanding of STBM guidelines among informants. Additionally, transportation facilities are privately owned, and STBM planning is conducted annually, but no specific STBM organization has been established at Cigugur Health Center. Socialization efforts are carried out through triggering activities and counseling, with both direct and indirect supervision by relevant stakeholders. The main obstacle in maintaining ODF status is limited funding, which hinders the sustainability of the program. Therefore, a strong collective commitment and improved funding strategies are essential to ensure that Harumandala and Kertajaya Villages can regain and sustain their ODF status.
The Influence of Business Diversification, Investment Decision and Good Corporate Governance on Firm Performance (An Empirical Study on Companies in The Industrial Sector in ASEAN from 2019 to 2022) Atmaja, Muhammad Zain Satria; Utami , Wiwik
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.50898

Abstract

This study aims to analyze and test the impact of Business Diversification, Investment Decisions, and Good Corporate Governance on Company Performance. Company performance is measured using Return on Assets (ROA), while the independent variables include Business Line, Asset Growth, and Institutional Ownership, with Company Size as a control variable. The research population consists of industrial sector companies listed on the Indonesia Stock Exchange, Singapore, Malaysia, Thailand, and the Philippines during the period of 2019-2022. The sample size was calculated using the Slovin formula, resulting in 95 companies, with 19 companies selected from each country (quota random sampling), totaling 380 data points for analysis. Data analysis was conducted using multiple linear regression with the aid of Eviews 12 statistical software. The results show that Business Diversification, Investment Decisions, and Institutional Ownership have a positive and significant impact on Return on Assets. Analysis for each ASEAN country concluded that business diversification does not have a significant effect in Indonesia, investment decisions do not have a significant effect in Malaysia, and Institutional Ownership does not have a significant effect in Thailand.
Analysis of The Advantages of Microsoft Teams as A Corporate Communication Tool in Supporting Employee Performance Melati, Ria
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.50900

Abstract

This study aims to evaluate the advantages of Microsoft Teams' features as a corporate communication tool that supports employee performance. The research methodology includes literature analysis and a Systematic Literature Review (SLR). Through SLR, this study collects, reviews, synthesizes, and summarizes various relevant studies on the topic. The research process begins with searching for related articles using the Publish or Perish application, which accesses the Scopus database with the keyword "Microsoft Teams Application as a Corporate Communication Tool in Supporting Employee Performance," limited to articles published between 2020 and 2024. The findings indicate that Microsoft Teams offers several key advantages in workplace communication and collaboration, such as comprehensive integration with third-party applications, flexibility and scalability, complete communication features, and high security and compliance standards. The use of Microsoft Teams has been proven to increase employee productivity by up to 20%, enhance employee engagement, and facilitate remote meetings, online training, and cross-department collaboration.
Analysis of Regional and Income Disparities in Nganjuk Regency: A Study Based on the Williamson Index and Gini Index Berliyan, Berliyan; Aldy Purnomo, Rochmat; Cahyono, Yeni; Santoso, Slamet; Abas, Sayid
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.50901

Abstract

This study addresses the issue of identifying regional disparity analysis, specifically to provide an overview of the level of development disparity in Nganjuk Regency in relation to welfare levels. By examining the income disparity of the population across regions, we can gain insights into the performance success of the economic development in Nganjuk Regency. This can serve as a foundation for future regional economic development planning. The research method employs descriptive analysis using secondary data from the Central Bureau of Statistics (BPS) of Nganjuk Regency, East Java Province, and Indonesia. The calculations of inter-regional income inequality through the Williamson Index and inter-household income inequality through the Gini Index both conclude that there is a rising trend of income inequality in Nganjuk Regency from 2022 to 2023. This increase in income inequality may be attributed to the economic slowdown in 2023, which impacts both regions and income groups, thus exacerbating disparities between regions and among individuals/households.
A Review on Mannich Base Derivatives Some of Natural Compounds: Antimicrobial Activities Siburian, Eva; Hayun, Hayun; Suryadi, Herman
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.50917

Abstract

This review explores the synthesis and antimicrobial potential of Mannich base derivatives derived from various natural compounds. The Mannich reaction, a versatile method in organic synthesis, enables structural modification of bioactive compounds to enhance their pharmacological properties, particularly antimicrobial activities. This study systematically reviews recent literature on the design, synthesis, and biological evaluation of these derivatives against bacterial and fungal pathogens. The findings demonstrate that Mannich base derivatives exhibit improved efficacy through multiple mechanisms of action, such as inhibition of cell wall synthesis, protein synthesis, and membrane disruption. The review highlights the relevance of Mannich-based structural optimization as a promising strategy in the development of novel antimicrobial agents.
Implementation of Flashcards in Increasing Arabic Vocabulary For Junior High School Grade 3 Students for Arabic Speaking Skills Novel, Novel; Murtadho, Nurul; Huda, Ibnul Samsul
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.50923

Abstract

This research is motivated by the learning situation in As-Sunnah Junior High School grade 3, which does not use interesting media in learning Arabic, so some students feel bored because of the monotony of learning. The purpose of this research is to design and develop Arabic vocabulary cards taken from the book Durus Al-Lughah Al-Arabiya Lighoiri Natiqin Biha and to find out the opinions of teachers and students about the feasibility of these Arabic vocabulary cards to be used in learning Arabic. The benefit of this research is that students learn vocabulary easily through the media of this vocabulary card for Arabic speaking proficiency. This study uses the R&D method with the ADDIE model (analysis, design, development, implementation, and evaluation). The results of this study obtained an average of 95% validation feasibility from design experts, 68% validation from material experts, 77.9% questionnaire scores obtained from 25 students and 80% of Arabic teachers, and the average result of the percentage of feasibility is 80.23%. So from the average feasibility score of 80.23%, it can be concluded that the Arabic flashcard is based on the book Durus Al-Lughah Al-Arabiya Lighoiri Natiqin Biha volume 2, chapters 16 to 31, which is taken from a conversation lesson written by Dr. Fii. Abdurrahim is interesting or good to be implemented in the 3rd grade of junior high school.
Determination of Total Flavonoid Levels of Bajakah Wood Extract (Spatholobus Littoralis Hassk) on Various Ethanol Concentrations and Antibacterial Activity Test of Staphylococcus Aureus Rahmasari, Siti; Ridwanto, Ridwanto; daulay, Anny sartika; Nst, Haris Munandar
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.50927

Abstract

The bajakah plant is one of the biological plants used in traditional medicine. Bajakah is also a medicinal herbal plant that can be used in all its parts. This plant can be found in the depths of Kalimantan Province, but it has not spread to other regions. There has been no effort to cultivate bajakah because of the lack of understanding of the local population about the use of this plant. This research includes the stages of processing plant materials, making ethanol extracts, characterization examinations, phytochemical screening, and determining total flavonoid levels of ethanol extract of Bajakah wood using the visible spectrophotometry method and antibacterial activity. Bajakah wood extract was made by maceration method using ethanol concentrations of 96%, 70%, and 50%, and the extract obtained was concentrated with a rotary evaporator, then the total flavonoid level was determined using the visible spectrophotometry method and antibacterial activity tests were carried out against Staphylococcus aureus As a positive control using chloramphenicol and negative control using dimethyl sulfoxide. The results were obtained by determining the maximum wavelength of quercetin and operating time, measuring the quercetin calibration curve, and calculating the total flavonoid level using the visible spectrophotometry method. The results obtained in the determination of total flavonoid levels in Bajakah wood ethanol extract at a concentration of 96% were 349.888 ± 4.5022 mg QE/g, at a 70% concentration of 307.137 ± 6.7626 mg QE/g and a 50% concentration of 6.15173 ± 2.9148 mg QE/g.

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