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Jember Medical Journal (JMJ)
Published by Universitas Jember
ISSN : -     EISSN : 29630428     DOI : 10.19184
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
ember Medical Journal (JMJ) publishes peer-reviewed original articles, case reports and literature review in basic medical research, clinical research, and applied medical science. This journal is published twice (May and November) by Faculty of Medicine Universitas Jember. Articles are original research that needs to be disseminated and written in English or Indonesia. All submitted manuscripts will go through the double-blind peer review and editorial review before being granted with acceptance for publication. Jember Medical Journal was issued for the first time in 2022. JMJ recieved the ISSN 2963-0428 for online version in 2022.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 32 Documents
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Perbandingan Regulasi dan Kondisi Faktual Penggunaan Pestisida di Asia Tenggara Jauhani, Muhammad Afiful; Latiefah Noer Widiastuti; Muhammad Naufal Hibatullah; Samuel Hendrik Marpaung
Jember Medical Journal Vol. 3 No. 2 (2024): .
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jembermedicaljournal.v3i2.1200

Abstract

Indonesia merupakan negara agraris dengan 40,6 juta penduduknya bekerja pada sektor pertanian. Akan tetapi, saat ini pemerintah Indonesia masih mengimpor produk pertanian dari negara lain, khususnya di Asia Tenggara, untuk memenuhi kebutuhan konsumsi dalam negeri. Kegiatan pertanian di berbagai negara umumnya menggunakan pestisida sebagai pengendali hama sehingga produk pertanian sangat mungkin terpapar pestisida yang menyebabkan gangguan kesehatan. Dalam rangka pengendalian dampak gangguan kesehatan akibat pestisida, diperlukan kebijakan pemerintah. Namun, kebijakan yang ada saat ini belum sepenuhnya dilaksanakan sehingga perlu diketahui kondisi faktual mengenai penggunaan pestisida. Penelitian ini bertujuan untuk menganalisis peraturan dan kondisi faktual mengenai penggunaan pestisida pada negara-negara di Asia Tenggara. Metode penelitian menggunakan tinjauan literatur menggunakan PICO dan kriteria inklusi yang telah ditentukan. Hasil penelitian menunjukkan bahwa negara-negara di Asia Tenggara telah memiliki regulasi yang mengatur tentang pestisida, meskipun masih terdapat beberapa negara yang belum mengatur perihal pestisida secara menyeluruh, Misalnya Singapura belum mencntumkan aspek pengujian, pembuatan, iklan, dan pemusnahan; Brunei Darussalam belum mencantumkan aspek pengujian, iklam, dan pencabutan izin.. Faktanya, masih banyak permasalahan terkait kepatuhan dan penerapan aturan mengenai penggunaan pestisida yang berdampak pada keamanan pangan pada negara-negara di Asia Tenggara. Peran pemerintah untuk mengendalikan dampak negatif yang diakibatkan pestisida masih perlu untuk dioptimalkan, melalui monitoring dan evaluasi ketat terhadap penggunaan pestisida dan pengawasan terhadap keamanan produk pangan hasil pertanian.
Potensi Terapeutik Ekstrak Daun Clitoria ternatea (Kembang Telang): Aktivitas Farmakologi, Profil Fitokimia, dan Keamanan Marpaung, Abdullah Muzi
Jurnal Agroteknologi Vol. 19 No. 2 (2025)
Publisher : Fakultas Teknologi Pertanian Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jagt.v19i2.60012

Abstract

Clitoria ternatea (butterfly pea) leaves constitute a unique phytochemical system within the species, rich in non-anthocyanin compounds that exhibit diverse pharmacological activities. While the flower has been extensively studied for its anthocyanin pigments, the leaf demonstrates broader and more sustained bioactivity due to its abundance of flavonoids, phenolic acids, triterpenoids, alkaloids, and cyclotides. This review critically examines the phytochemical composition, pharmacological mechanisms, and safety profile of C. ternatea leaves based on contemporary experimental and analytical evidence. Quantitative analyses reveal that leaf extracts possess higher total phenolic and flavonoid contents than other plant parts, correlating with strong antioxidant and antidiabetic capacities. Major bioactives such as taraxerol, vasicine-type alkaloids, and the cystine-knot cyclotide Cter M contribute synergistically to antioxidant defense, anti-inflammatory modulation, and glucose regulation. Experimental findings also indicate analgesic, antimicrobial, and neuroprotective activities mediated through inhibition of COX-2, α-glucosidase, and acetylcholinesterase, along with enhancement of Nrf2-dependent antioxidant pathways. Toxicological studies suggest a wide safety margin, with oral LD₅₀ values exceeding 2000 mg/kg and no significant histopathological alterations in vital organs. The absence of major adverse effects supports the short-term safety of leaf extracts, although data on chronic and reproductive toxicity remain insufficient. Overall, available evidence identifies C. ternatea leaves as a promising source of multifunctional bioactive compounds with considerable potential for future development in phytopharmaceutical and nutraceutical applications.Keywords: health benefits, medicinal plants, pharmacological activities, phytochemical composition
Performance of Microhydro Power Plant in Tlocor Village, Banyuwangi, East Java for Households and Post-Harvest Processing Rahmanto, Dedy Eko; Wibowo, Michael Joko; Faizin, Nur; Fahriannur, Ahmad; Aurelya , Azza Auliya Rahma
Jurnal Agroteknologi Vol. 19 No. 2 (2025)
Publisher : Fakultas Teknologi Pertanian Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jagt.v19i2.60014

Abstract

Microhydro power plants utilize the kinetic energy of water to spin a turbine and the turbine rotation is used to spin a generator so that it can produce electricity. One example of a microhydro power plant is the Tlocor microhydro located in Tlocor village, Banyuwangi, East Jawa, Indonesia. Tlocor microhydro uses a crossflow turbine and 8 kw synchronous generator. Tlocor microhydro needs to be investigated to determine its performance and development potential. The research was carried out by observing water discharge using a current meter and observing electrical parameters using a power logger and testing voltage drop. The river water discharge is 0.36 m3/s and the turbine used is 0.21 m3/s. The normal daily electrical voltage for Tlocor microhydro is 217.37 volts with a voltage drop at the farthest consumer of 0.68 volts. The resulting electrical frequency is an average of 49.9 Hz. The normal daily electrical power produced by Tlocor microhydro reaches 2605.5 watts. The micro-hydro electrical power produced still has the potential to be increased if the water flow entering the turbine is increased. This can be done if the need for electrical power increases or is used for economic empowerment of communities using Tlocor microhydro.Keywords: electrical, generator, microhydro, water discharge
Karakteristik Fisikokimia dan Antioksidan Minuman Herbal Bunga Telang pada Berbagai Proporsi Daun Rambusa dan Beluntas Widyawati, Paini Sri; Epriliati, Indah; Purwanto, Agus; Simanjuntak, Melvin Emil
Jurnal Agroteknologi Vol. 19 No. 2 (2025)
Publisher : Fakultas Teknologi Pertanian Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jagt.v19i2.60016

Abstract

Pluchea herbal drink has less attractive color and sensory characteristics so that it needs the addition of other herbal ingredients to improve it, especially butterfly pea flowers. Using of butterfly pea flowers at 60% w/w proportion can increase panelist acceptance, but its antioxidant activity is reduced. Therefore, it is necessary to combine pluchea leaves with stinking passion flower leaves to increase its antioxidant activity. The stinking passion flower is a herbal plant that has the potential as an antioxidant because it contains flavonoids, alkaloids, steroids, triterpenoids, saponins, and tannins. The purpose of this study was to determine the physicochemical and antioxidant characteristics of butterfly pea herbal drink in various proportions of stinking passion flower-pluchea leaves. The results showed that increasing the proportion of stinking passion flower leaves did not change the intensity and blue color of the butterfly pea herbal drink, but the turbidity level decreased along with the increase in pH value and the decrease in total acid value. The addition of stinking passion flower leaves up to a proportion of 70% w/w was able to increase the total phenol content (TPC) and antioxidant activity (DPPH free radical scavenging activity and iron ion reducing power/ FRAP), but the total flavonoid content/TFC decreased along with the increase in the proportion of stinking passion flower leaves. The combination of stinking passion flower-pluchea leaves up to a proportion of 70:30 % w/w is the right proportion to increase the total phenol content and antioxidant activity of the butterfly pea flower herbal drink.Keywords: antioxidant, butterfly pea flower, herbal drink, pluchea leaf, stinking passion flower leaf
Kapasitas dan Stabilitas Senyawa Antibakteri Ekstrak Kulit Kayu Akway (Drimys piperita) terhadap Pertumbuhan Escherichia coli Patogenik Roreng, Mathelda Kurniaty; Cepeda, Gino Nemesio
Jurnal Agroteknologi Vol. 19 No. 2 (2025)
Publisher : Fakultas Teknologi Pertanian Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jagt.v19i2.60029

Abstract

Drimys piperita known with local name of akway by Sougb tribe communities lived in district of Anggi, regency of Pegunungan Arfak, Province of West Papua. The. Plant was used as tradisional medicines for treating malaria and enhancing vitality. The objectives of research were to know the group of compounds composed of akway bark ethanolic extracts, potency of akway extracts as an antibacterial agent on inhibiting growth of pathogenic Escherichia coli and stability of antibacterial compounds of extract on heating of 100ºC for 0−20 minutes. Qualitative assays of compounds composed extract were done on compound class of terpenoids, alkaloids, saponins, flavonoids, tannins dan steroids. Antibacterial capacity and stability assays were done by using agar well diffusion method. The results indicated that ethanolic extracts of akway content compound class of terpenoids, alkaloids, saponins, flavonoids, and tannins. Ethanolic extracts of akway could inhibit growth of pathogenic Escherichi coli ATCC 43894 and ATCC10798 on minimum inhibiting concentration of 1.05% and 1.26% respectively. The antibacterial properties of akway extract was stable on heating of 100ºC for 0−20 minutes. Ethanolic extracts of akway bark was potential as source of natural antibacterial agent for inhibiting growth of pathogenic E. coli.Keywords: antibacterial capacity, Drimys piperita, extracts, stability
Peningkatan Mutu Fungsional Kombucha dengan Penambahan Kunyit sebagai Sumber Antioksidan dan Pewarna Alami Fauzi, Mukhammad; Azmiyah, Mafazatul; Bakri, Abi
Jurnal Agroteknologi Vol. 19 No. 2 (2025)
Publisher : Fakultas Teknologi Pertanian Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jagt.v19i2.60055

Abstract

Turmeric is a rhizome known to contain high levels of curcumin. It’s primarily processed into traditional beverages such as herbal medicine (jamu) ready to drink or its instant powder. Turmeric can be used to make a contemporary fermented beverage, i.e. kombucha. This study aims to determine the effect of adding turmeric and fermentation time in improving the quality of antioxidant properties and natural color as well as the physical, chemical, and sensory properties of turmeric kombucha. Unpeeled turmeric was washed and sliced, and then kombucha was made with concentrations of 4%, 6%, and 8% turmeric (w/v) in 500 mL of a 10% sugar solution. This mixture was boiled for 10 minutes, then filtered and cooled to 29–30°C. Then, 10% SCOBY starter was added and fermented for 6, 8, 10, and 12 days. Parameters such as antioxidant activity lightness, yellowness, total solids, pH, total titratable acid, and organoleptic properties were measured. Parameters such as antioxidant activity, lightness, yellowness, total solids, pH, total titratable acid, and organoleptic properties were measured. The percentage of turmeric and fermentation time significantly affected the quality of antioxidant activity against DPPH, color brightness value, yellowness value, pH, total titratable acid, and, as well as panelists' preference for the organoleptic properties of turmeric kombucha. Effectively, turmeric kombucha drink made from 6% turmeric and fermented for 8 days was characterized by antioxidant activity of 71.27%, brightness of 67.67, total soluble solids of 12.19%, pH 3.52, total titratable acid of 0.41%, and overall preference value of 5.63 (like). In the future, turmeric kombucha can be consumed as a functional kombucha-based beverage. Keywords: antioxidant activity, curcumin, turmeric, kombucha, sensory
Correlation of Social Adjustment with Depression, Anxiety, and Stress in First-Year Medical Students Kusumastuti, Inke; Khazimi Husein, Asagiri; Cholis, Abrori
Jember Medical Journal Vol. 5 No. 1 (2026)
Publisher : Fakultas Kedokteran, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Transisi kehidupan, antara lain dalam bentuk menjadi mahasiswa baru, secara alami melibatkan proses penyesuaian dalam kehidupan individu. Mahasiswa baru yang harus beradaptasi dengan lingkungan baru berisiko mengalami depresi, stres, atau cemas yang relatif tinggi, Pada fakultas kedokteran, prevalensi stres psikologis lebih tinggi dibanding mahasiswa non fakultas kedokteran di populasi umum. Karenanya, penelitian analitik korelasional ini dilakukan untuk mengetahui hubungan penyesuaian sosial dengan depresi, cemas, dan stres pada mahasiswa kedokteran Universitas Jember tahun pertama. Kuesioner Depression, Anxiety, and Stress Scale 42 item (DASS-42) digunakan untukmenilai derajat depresi, cemas, dan stres, sementara Social Readjustment Rating Scale (SRRS) Holmes dan Rahe digunakan untuk menilai penyesuaian sosial. Pengisian kuesioner dilakukan secara daring melalui google form. Sebanyak 120 peserta dengan rerata usia 19 tahun dan didominasi perempuan (75,8%) mengisi kuesioner. Pasca analisis, tidak didapatkan hubungan signifikan antara penyesuaian sosial dengan depresi, cemas, dan stres pada responden, sehingga perlu dipertimbangkan untuk melakukan penelitian terhadap faktor-faktor lain yang dapat terkait.
The Correlation Between Coconut-Based Food Consumption and Blood Pressure Status of Patients at Sumbersari Health Center in Jember Prasetyo, Aris; Muhammad, Maulana Sava
Jember Medical Journal Vol. 5 No. 1 (2026)
Publisher : Fakultas Kedokteran, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hypertension is a major risk factor for cardiovascular disease worldwide. Dietary components, including coconut-based foods widely consumed in Indonesia, contain bioactive compounds such as potassium, lauric acid, and flavonoids that may influence blood pressure regulation through antioxidant, anti- inflammatory, and vasodilatory mechanisms. However, clinical evidence at the primary healthcare level remains limited. Objective: This study aimed to determine the relationship between coconut-based foodconsumption and blood pressure status among patients at Sumbersari Primary Health Center, Jember. This observational analytic study utilized a cross-sectional design involving 69 respondents selected via consecutive sampling. Dietary intake was assessed using a Food Frequency Questionnaire (FFQ), and blood pressure was measured directly using a digital sphygmomanometer. Data were analyzed using the Pearson Chi-Square test (α = 0.05). Results: The majority of respondents were young adults with a normal Body Mass Index (BMI) and healthy lifestyle patterns. The bivariate analysis revealed no statistically significant relationship between the total consumption of coconut-based food and blood pressure status p = 0.571. Nevertheless, a descriptive analysis indicated a positive clinical trend, wherein the proportion of hypertension was lower in the moderate and high consumption groups comparedto the low consumption group. This lack of statistical significance is likely attributed to the respondents' optimal health profile, as well as food matrix factors, including high-temperature processing that degrades bioactive compounds and concurrent high sodium intake. Coconut-based food consumption was not significantly associated with blood pressure status in this population. However, the descriptive analysis indicated a positive clinical trend, wherein the proportion of hypertension was lower in the moderate and high consumption groups suggesting potential biological relevance that warrants further investigation in larger and more diverse populations.
Hubungan Lama Ketuban Pecah Dini pada Kehamilan Aterm dengan Kejadian Asfiksia Neonatorum di RSD dr. Soebandi Jember Isbach, Galuh; David Lahindah, Stephanus; Dita Diana , Parti; Elly Nurus , Sakinah; Dion, Krismashogi Dharmawan
Jember Medical Journal Vol. 5 No. 1 (2026)
Publisher : Fakultas Kedokteran, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Salah satu komplikasi paling sering terjadi pada bayi baru lahir adalah asfiksia neonatorum. Asfiksia neonatorum adalah kegagalan dalam menginisiasi dan mempertahankan pernapasan secara spontan sesaat setelah dilahirkan. Penelitian ini bertujuan untuk menganalisis hubungan antara ketuban pecah dini (KPD) pada kehamilan aterm dan kejadian asfiksia neonatorum pada bayi baru lahir di RSD dr. Soebandi Kabupaten Jember. Penelitian ini menggunakan jenis penelitian analitik observasional dengan pendekatan cross sectional. Sampel penelitian terdiri atas 72 sampel ibu dengan kehamilan aterm yang mengalami KPD di RSD dr. Soebandi Kabupaten Jember. Data dikumpulkan melalui rekam medis dan dianalisis menggunakan uji statistik Chi-Square untuk mengetahui hubungan antara variabel independen (KPD pada kehamilan aterm) dan variabel dependen (asfiksia neonatorum). Hasil analisis menunjukkan bahwa terdapat hubungan yang signifikan antara KPD pada kehamilan aterm dengan kejadian asfiksia neonatorum (p-value = 0,001). Ibu yang mengalami KPD > 12 jam mempunyai risiko sebesar 5,6 kali lebih tinggi dibandingkan dengan ibu yang mengalami lama KPD < 12 jam (OR = 5,6). Evaluasi yang cepat dan penanganan yang tepat waktu sangat penting untuk mengurangi risiko asfiksia neonatorum.
Pengaruh aktivitas fisik terhadap derajat keparahan osteoarthritis lutut berdasarkan klasifikasi kellgren–Lawrence Elsafrida, Artia Rizqi Wardhani; Muhamad , Hasan
Jember Medical Journal Vol. 5 No. 1 (2026)
Publisher : Fakultas Kedokteran, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Osteoartritis lutut merupakan salah satu penyakit degeneratif sendi yang paling sering dijumpai dan menjadi penyebab utama nyeri serta disabilitas pada usia dewasa hingga lanjut usia. Prevalensinya terus meningkat seiring bertambahnya usia harapan hidup dan perubahan gaya hidup masyarakat. Sendi lutut sebagai sendi penopang beban tubuh sangat rentan mengalami kerusakan struktural akibat tekanan mekanik yang berulang, terutama pada individu dengan aktivitas fisik berat. Tingkat keparahan osteoartritis lutut secara radiologis umumnya dinilai menggunakan klasifikasi Kellgren–Lawrence yang menjadi standar dalam praktik klinis dan penelitian. Namun, hubungan antara aktivitas fisik dan derajat keparahan osteoartritis lutut masih menunjukkan hasil yang bervariasi, khususnya pada populasi dengan karakteristik pekerjaan dan gaya hidup tertentu seperti masyarakat Kabupaten Jember. Penelitian ini bertujuan untuk mengetahui pengaruh aktivitas fisik terhadap derajat keparahan osteoartritis lutut berdasarkan klasifikasi Kellgren–Lawrence. Penelitian ini merupakan penelitian observasional analitik dengan desain potong lintang (cross-sectional), dilaksanakan di Poli Ortopedi Rumah Sakit Bina Sehat Jember pada periode Agustus hingga November 2025. Subjek penelitian adalahpasien yang terdiagnosis osteoartritis lutut secara klinis dan radiologis serta memenuhi kriteria inklusi dan eksklusi. Pengambilan sampel dilakukan dengan teknik total sampling. Data aktivitas fisik diperoleh melalui kuesioner Global Physical Activity Questionnaire (GPAQ), dan derajat keparahan osteoartritis berdasarkan klasifikasi Kellgren–Lawrence diperoleh dari rekam medis dan pemeriksaan radiografi lutut. Analisis data dilakukan menggunakan uji korelasi Spearman, serta multivariat menggunakan regresi logistik ordinal dengan pengendalian variabel usia dan jenis kelamin. Hasil penelitian menunjukkan bahwa aktivitas fisik memiliki hubungan bermakna dengan derajat keparahan osteoartritis lutut. Aktivitas fisik dengan intensitas tinggi cenderung berhubungan dengan derajat osteoartritis yang lebih berat. Analisis multivariat menunjukkan bahwa aktivitas fisik tetap berpengaruh signifikan terhadap derajat keparahan osteoartritis setelah dikontrol oleh usia dan jenis kelamin, dengan aktivitas fisik sebagai faktor yang memiliki pengaruh paling kuat. 

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