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Journal of Pharmaceutical and Sciences.

jps
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Published by Universitas Tjut Nyak Dhien

ISSN : - EISSN : 26563088 DOI : https://doi.org/10.36490/journal-jps.com

Core Subject : Health, Science, Agriculture, Engineering,

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 555 Documents

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Studi Aktivitas Antibakteri Ekstrak Etanol Daun Stroberi (Fragaria x ananassa (Weston) Rozier) Terhadap Bakteri Propionibacterium acnes Mandike Ginting; Pricella Ginting; Sinta Apriliana Sari
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Background; Strawberry leaves (Fragaria x ananassa (Westo) Rozier) contain tannin, flavonoids; secondary metabolites which have antibacterial properties, whereby the flavonoids can disrupt the function of the bacterial cell wall, while the tannins can inhibit microbial extracellular enzymes. Method; Experimental research with the maceration method using 70% ethanol. The ethanol extract of strawberry leaves (Fragaria x ananassa (Weston) Rozier) was used in this study, and it was tested for the simple characteristic test, the phytochemical screening test, and the antibacterial activity test using the disc diffusion method with sample concentrations of 10%, 12%, and 14%. Results; The results obtained from the simplicial characteristic test showed that the simplicial met the requirements for the water content test, water-soluble essence test, ethanol-soluble extract content test, total ash content test, and acid-soluble ash content test. The phytochemical screening showed that strawberry leaves contained alkaloids, flavonoids, tannins, and saponins. The antibacterial activity test showed that the ethanol extract of strawberry leaves (Fragaria x ananassa (Weston) Rozier) had an inhibitory effect on the growth of Propionibacterium acnes bacteria with an extract concentration of 10%, 12%, and 14% showing a diameter of inhibition zone of 17.3 mm respectively, 17.78 mm and 19.08 mm. Conclusion; The results of the research on the optimal concentration of the ethanol extract of Strawberry leaves (Fragaria x ananassa (Weston) Rozier) against Propionibacterium acnes bacteria at a concentration of 14% resulted in a diameter of 19.08 mm inhibition zone, this antibacterial activity is in a strong category.

Formulasi Sediaan Lipstik Menggunakan Pewarna Alami Kopigmentasi Biji Kesumba Keling (Bixa orellana L.) Dengan Angkak Merah Sebagai Pewarna Salman Salman; Muhammad Iskandar; Sudewi Sudewi; Meutia Indriana
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Background; appearance is the most common thing to pay attention to, especially among women. Cosmetics are preparations that can improve appearance, one of which is lipstick. Lipstick has the main components, namely wax, oil and dye. One of the natural dyes that can be used as cosmetic dyes are annatto (Bixa orellana L.) and red yeast rice seeds. However, the use of natural dyes in cosmetics has an unstable color. The purpose of this study was to stabilize the dye from annatto (Bixa orellana L.) with red yeast rice seeds using the copigmentation method. Methods; in this study, a maceration process was carried out to obtain extracts from annatto (Bixa orellana L.) and red yeast rice seeds with a ratio of 1:10 (w/v). Then mixed with the thick extract of annatto (Bixa orellana L.) with red yeast rice as a coloring agent, formulated in a ratio of 1:1, 1:2, 2:1 and 2:2. Then the physical quality test of the lipstick preparation was carried out which included homogeneity test, melting point test, lipstick strength test, stability test, smear test, and irritation test. Result; the results showed that the Annatto (Bixa orellana L.) with red yeast rice in the form of copigmentation can be formulated into lipstick preparations with poor homogeneity results. All lipstick preparations meet the requirements of the melting point test, strength test, stability test, smear test, irritation test. The formula with a ratio of 1:2 (F2) is the most preferred preparation by volunteers because it has a good color, smell and texture.

Review Artikel : Pelaksanaan Telefarmasi Pada Pelayanan Kefarmasian Di Farmasi Komunitas Firda Riska Rahayu; Iqbal Sujida Ramadhan; Rini Hendriani
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

During the 21st of century, the use of information technology and telecommunications is proliferating, including in the healthcare sector. One of the health services is telepharmacy. Telepharmacy is a relatively new concept, so research is needed to optimize the application of telepharmaceuticals. Based on that, this article explains the implementation of telepharmacy in various countries and the advantages and limitations of telepharmacy. The methods were carried out by searching electronically through Google scholar, Pubmed, ScienceDirect, and NCBI. A total of 24 journals and three regulations fulfilled the inclusion criteria. This review shows that telepharmacy has been carried out in many countries, such as in Asia, Europe, America and Africa. The form of implementation is different by each country, for example, through a platform, video conferencing, chat messenger and telephone. In addition, to the advantages, several challenges involve cooperation between patients, the government and private sectors, as well as academic institutions, which is essential for achieving appropriate results and effectively improving health services.

Review: Penggunaan Off-Label Obat Golongan Antagonis Reseptor Histamin 2 Indah Sari; Ellin Febrina
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Histamine 2 (H2) receptor antagonist drugs have been widely used for a wide range of indications, including for use as off-label drugs. Even though it can potentially increase the risk of adverse drug reactions, under certain conditions, using off-label drugs is the only option for medical personnel. This review aims to provide an overview of the widespread off-label use of H2 receptor antagonists, including ranitidine, cimetidine, famotidine, and nizatidine. The results of this review are expected to be used as evaluation material by the government, drug manufacturers, and health practitioners. The method used in this review is a study of literature obtained through several services, such as PubMed®, ScienceDirect®, and Google Scholar. The results of this review show that using off-label H2 receptor antagonist drugs is a curative and preventive effort to overcome several diseases, namely off-label in the categories of patient age, dosage, and indications.

Artikel Review: Pengaruh pH pada Pertumbuhan Bakteri Sesuai Syarat Mutu Obat Tradisional di Indonesia Ivanny O. Y. Sinaga; Dwie Astrini; Raden B. Indradi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Traditional medicine comes from safe ingredients, namely, parts of plants. Based on BPOM No. 32 of 2019, several bacteria are required for the quality of traditional medicines in Indonesia, including Escherichia coli, Clostridia, Salmonella, and Shigella. An optimal pH medium is also needed in the microbial contamination test to produce optimal bacterial growth data. The method used is library search using electronic databases such as Google Scholar and Pubmed with the keywords "Effect of pH on bacterial growth" and other keywords related to microbes and types of bacterial contamination. The inclusion criteria were the sources published in the last ten years, either in English or Indonesian, with exclusion criteria being any sources published that did not discuss the effect of pH on bacterial growth. A total of 24 articles were found, with the final result being 11 articles reviewed. It was found that a difference in pH of at least 0.5 can significantly affect the growth of bacteria.

Artikel Review : Perencanaan Pola Pengambilan Sampel Produk Antara pada Validasi Proses Ayu Nursiti Fatimah; Muchtaridi Muchtaridi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

The pharmaceutical industry must be able to ensure certainty in the production process through validation throughout the production process. Therefore, it is necessary to carry out process validation to ensure that every parameter and procedure used in each intermediate product production process obtains results that meet the requirements and specifications required. A sample is one of the guidelines in conducting process validation, so it is necessary to plan to determine the collection location based on risk and scientific reasons. This review aims to provide information on the tools used during the sampling process and the number of sample points taken on solid, semi-solid, and non-sterile liquid drug product preparations. Hopefully, this review can be a consideration for the pharmaceutical industry in planning sampling for the intermediate product during process validation. The method used is a library search from databases available online from ScienceDirect and standards from authoritative institutions. The results obtained in this review are tools that can be used in sampling patterns for solid preparations, namely thief samplers, simple bag-sampling spears, and scoop and for liquid and semi-solid non-sterile preparations, dip tubes and weighted containers. In the sampling pattern during the mixing process of the solid, there are 10 locations of sampling. While in the sampling pattern during the process of mixing liquid and semi-solid non-sterile, there are 9 locations of sampling. With this validity, it can represent the consistency of product quality.

Evaluasi Sistem Penyimpanan Obat Berdasarkan Standar Pelayanan Kefarmasian Pada Salah Satu Apotek Di Kota Bandung Sagita DwiDara; Asti Yunia Rindarwati; Raisa N Fadillah; Yoppi Iskandar
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Storage is an act of storing and securing medicines in a protected place. Drug quality is essential to be maintained through storage. An improper storage system can cause drug ineffectiveness. The research objective was to evaluate the drug storage system at the Bandung Pharmacy. The research method used is descriptive observation, and the evaluation is carried out by observing the activities in the pharmacy. The results showed that the drug storage system in one of the pharmacies in the city of Bandung complies with the Regulation of the Minister of Health of the Republic of Indonesia No. 73 of 2016 concerning Pharmaceutical Service Standards at Pharmacies, which is 80%, where this value is included in the "Good" storage criteria.

Review Artikel: Memperbaiki Permeabilitas Obat Bcs Kelas II, III Dan IV Dengan Metode Ko-Amorf Vicania Raisa Rahman; Arif Budiman
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Drugs in the co-amorphous form are combinations of amorphous drugs with co-formers that have good solubility and stability so that dissolution becomes better and influences the therapeutic effect of drugs better, too the first time a co-amorphous formulation was made to overcome the low solubility of BCS class II. However, the current study found that co-amorphous formulations could improve solubility and the permeability of BCS class III and IV drugs. Co-amorphous production methods include cryo-milling, melting and quench cooling, solvent evaporation, and spray drying. This article review was conducted to gather information about BCS class II, III, and IV drugs made in co-amorphous forms to improve the physicochemical properties of drugs, such as solubility, permeability, and stability. Articles were collected from 20 research journals published over the last ten years. The co-amorphous drug testing of 10 drugs showed higher solubility and permeability than in crystal form

Kajian Farmasi Klinis Penggunaan Obat Batuk “X” Dengan Kandungan Bromheksin HCl Untuk Pengencer Dahak Pada Anak Lisna Nur Imani; Keri Lestari; Wida Mulyaningsih
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Cough is a physiological reflex that occurs to protect the lungs from mechanical trauma or a natural defense process to maintain the respiratory tract by preventing the ingress of foreign bodies in the respiratory tract. Children are particularly susceptible to a wide variety of diseases such as acute respiratory infections. There are 3 types of cough medicines sold freely in Indonesia, namely for coughing up phlegm, dry cough and allergic cough, where the drug content in each type of cough medicine is different. Cough medicine X is a sputum-thinning cough medicine containing bromhexine HCl that works to dilute sputum in the respiratory tract. This article contains clinical pharmaceutical studies related to cough medicine X with the active substance bromhexine HCl. Based on the results of clinical pharmaceutical studies, cough x medicine can be used as a treatment for cough phlegm in children.

Faktor Yang Memengaruhi Perilaku Perawat Dalam Pemilahan Limbah Medis Di Ruang Rawat Inap Rumah Sakit Umum Sundari Medan Dyna Safitri Rakhelmi Rangkuti; Andini Mentari Tarigan; Tiwi Amelia
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Background; Sundari Hospital Medan generates 762kg of medical waste yearly, with the inpatient room producing the most. Nurses segregate medical waste, both infectious and non-infectious, in violation of the provisions; this is thought to be due to factors such as knowledge, years of service, attitudes, the availability of facilities, and the use of less stringent sanctions. Purpose; The study examined the factors influencing nurses' behavior when sorting medical waste. Method; This research employed a descriptive method with a cross-sectional approach. The population was 52 inpatient nurses; all were taken as study samples. A questionnaire was used to collect data. The data was analyzed using univariate, bivariate, and multivariate analysis and the chi-square test. Result; The results showed that knowledge of values (0.03<0.05), years of service (0.043<0.05), attitudes (0.035<0.05), availability of facilities (0.025<0.05), availability of information (0.032< 0.05), policy (0.018 <0.05), has an effect on behavior in sorting medical waste because it is smaller than 0.05. Educational factors (0.249 <0.05) have no effect. The most influential variable is the policy with the value of Sig. 0.018. Conclusion; This study concluded that knowledge, years of service, attitudes, availability of facilities, information, and policies influence nurses' conduct when sorting medical waste. However, education has little effect. The policy was the most influential variable. The hospital should make and implement punishments for nurses who do not sort medical waste according to protocol; the hospital should arrange continual training/socialization, analyzes every month, and increase the number of medical waste sorting facilities.

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Salman

Contact Email salman.kimia@gmail.com

Phone +6285277011177

Journal Mail Official admin@journal-jps.com

Editorial Address Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location Kota medan, Sumatera utara INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Salman

Contact Email
salman.kimia@gmail.com

Phone
+6285277011177

Journal Mail Official
admin@journal-jps.com

Editorial Address
Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location
Kota medan,

Sumatera utara

INDONESIA