cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Salman
Contact Email
salman.kimia@gmail.com
Phone
+6285277011177
Journal Mail Official
admin@journal-jps.com
Editorial Address
Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123
Location
Kota medan,
Sumatera utara
INDONESIA
Journal of Pharmaceutical and Sciences.
Published by Universitas Tjut Nyak Dhien
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490/journal-jps.com
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 698 Documents
 64   65   66   67   68 
Pelayanan Farmasi untuk Daerah Tertinggal, Terdepan, dan Terluar (3T) Terkait Program Penyakit HIV Berdasarkan Integrasi Model Pemberi Layanan yang Terdiferensiasi (PLD): Sebuah Tinjauan Sistematis Renaldi, Fransiskus Samuel; Pangeran, Khrisna
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1331

Abstract

Background: Differentiated Service Delivery (DSD) has been proposed to improve HIV treatment continuity in remote areas; however, its success depends on the integration of systemic supports. Objective: This review synthesizes evidence on the effectiveness of community-based DSD models and the determinants of their success in underdeveloped, frontier, and outermost (3T) areas, particularly concerning supply chain resilience, quality assurance, and aligned governance and financing. Methods: A systematic review with narrative synthesis was conducted following PRISMA guidelines. Literature searches were performed in PubMed, Scopus, Web of Science, and grey literature repositories (2010–2025). Out of 1,520 records, 32 studies met the inclusion criteria. Results: Community-based DSD models (ART groups, MMD) were effective in improving adherence, retention, and reducing visit burden. This success was strongly determined by: (1) ARV supply chain stability (minimal stock-out days, synchronization with MMD schedules); (2) quality assurance in storage–distribution (temperature control, FEFO); and (3) aligned governance and financing (pharmacist roles, community health worker incentives, last-mile funding). Qualitative findings identified service proximity, confidentiality, and logistical reliability as key facilitators. Conclusion: DSD is a systemic intervention whose effectiveness hinges on multidimensional readiness. Strengthening HIV pharmaceutical services in 3T areas requires an integrated approach that simultaneously builds supply resilience, service quality, and adaptive governance. This review proposes operational indicators and a phased implementation roadmap for contextual adaptation.
Formulasi dan Uji Efektivitas Ekstrak Bayam Duri (Amaranthus spinosus L.) Sebagai Krim Antibakteri Terhadap Bakteri Cutibkterium acnes dan Staphylococcus aureus Daulay, Anna miroh; Rasyidah, Rasyidah
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1332

Abstract

Acne vulgaris is a common skin problem in adolescents that often causes stress, anxiety, and decreased self confidence. Spiny Amaranth (Amaranthus spinosus L.) has antibacterial potential, but its effectiveness against Cutibacterium acnes has not been fully explored. This study aims to develop a cream formulation of Spiny Amaranth leaf ethanol extract and test its antibacterial effectiveness against Cutibacterium acnes and Staphylococcus aureus. The research method includes extraction of Spiny Amaranth leaves, cream preparation, and antibacterial activity test using the disc diffusion method. The results showed that the antibacterial cream of Spiny Amaranth leaf extract has good effectiveness against the growth of Cutibacterium acnes and Staphylococcus aureus, with an increasing inhibition zone along with the increase in extract concentration, namely 18.5 mm at 25% concentration and 27.9 mm at 50% concentration for Cutibacterium acnes, and 16.0 mm at 25% concentration and 23.3 mm at 50% concentration for Staphylococcus aureus. The characteristics of the cream that are suitable for the skin and the stable emulsion type make this cream ideal for skin application. The results of this study indicate that the antibacterial cream of Spiny Amaranth leaf extract can be used as an effective alternative natural antibacterial treatment.
Analisis Kontaminasi DNA Babi (Sus scrofa domesticus) Pada Produk Olahan Bakso Sapi Dan Ayam di Tuntungan, Sumatera Utara Sandika , Febri; Idami, Zahratul; Idris, Muhammad
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1374

Abstract

Background: Meatballs are a popular processed meat product in Indonesia. High consumption of meatballs is accompanied by increasing public concern, especially among Muslims, regarding the halal aspect of the product. The potential contamination of pork DNA (Sus scrofa domesticus) in beef and chicken meatballs is a critical issue, whether due to unintentional cross-contamination or adulteration. Tuntungan area, North Sumatra, with its diverse demographic and trading characteristics, is an important location to assess the level of contamination. Objective: This study aimed to detect the presence of pork DNA (Sus scrofa domesticus) contamination in processed beef and chicken meatball products traded in the Tuntungan area, North Sumatra. Methods: Four meatball samples (three chicken meatballs and one beef meatball) were collected from street vendors and meatball stalls at different locations. DNA detection was performed molecularly using the Real-Time Polymerase Chain Reaction (qPCR) method with the *Genechecker UF-300* instrument. The procedure began with sample preparation, DNA extraction using the Genolution tool, master mix preparation, and analysis using the PCR Gen Checker chip. Result validation was based on the Cycle threshold (Ct) value in the target channel (FAM for pork DNA) and the internal control channel (ROX). Results: The analysis results of all four samples showed a FAM Ct value of 0 (not detected), indicating no amplification of specific pork target DNA. Meanwhile, the ROX Ct value (internal control) in all samples was detected in the range of 19.41–20.50, proving that the DNA extraction and amplification process ran optimally without inhibition. The positive control showed valid amplification signals, and the negative control showed no contamination. Conclusion: Based on the molecular detection results, it can be concluded that all tested beef and chicken meatball samples from the Tuntungan area were not contaminated with pork DNA (Sus scrofa domesticus). This finding indicates that traders in the area have applied good processing practices and separated raw materials, so the meatballs sold meet the halal aspect in terms of ingredient authenticity.
Determinan Kepatuhan Pasien Tuberkulosis Paru Dalam Menjalani Pengobatan di UPT. Puskesmas Simalingkar Tahun 2024 Barus , Nanda Isabel; Manurung, Kesaktian; Hutajulu , Johansen; Wandra , Toni; Girsang , Vierto Irennius
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1386

Abstract

Background: Pulmonary tuberculosis (TB) is a chronic infectious disease that remains a major global and national public health problem, with Indonesia ranking second among countries with the highest TB burden worldwide. Non-adherence to treatment is one of the main barriers to successful TB control, as it may lead to treatment failure, drug resistance, and increased morbidity and mortality. At the Simalingkar Community Health Center (UPT Puskesmas Simalingkar), the specific factors determining treatment adherence among pulmonary TB patients have not been extensively studied. Objective: This study aimed to analyze the determinants of treatment adherence among pulmonary tuberculosis patients at the Simalingkar Community Health Center in 2024. Methods: This study employed an analytical cross-sectional design. The study population consisted of all pulmonary TB patients undergoing treatment at the Simalingkar Community Health Center, with a total sample of 90 respondents selected using a total sampling technique. Data were collected through questionnaires and medical records, and analyzed using univariate, bivariate (Chi-square test), and multivariate (logistic regression) analyses, with a significance level of p < 0.05. Results: A total of 77.8% of patients were adherent to treatment. Bivariate analysis showed significant associations between education (p < 0.001), employment status (p = 0.004), knowledge (p = 0.006), and health care services (p = 0.011) with treatment adherence. Age, sex, and family support were not significantly associated with adherence. Multivariate analysis indicated that the most dominant factor associated with treatment adherence was educational level (OR = 9.004; 95% CI: 2.58–31.49), followed by employment status (OR = 5.59; 95% CI: 1.48–21.12), and health care service support (OR = 3.99; 95% CI: 1.09–14.56). Conclusion: The significant determinants of treatment adherence among pulmonary TB patients at the Simalingkar Community Health Center were educational level, employment status, and health care service support, with education being the most dominant factor. It is recommended that TB control programs place greater emphasis on interventions aimed at improving health literacy, socio-economic support, and the quality and accessibility of health care services to enhance treatment adherence.
Formulasi Granul Effervescent Mengandung Ekstrak Daun Cyclea barbata Miers: Evaluasi Fisik (Sebelum dan Sesudah Rekonstitusi) Endriyatno, Nur Cholis; Oktavian , Rangga
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.893

Abstract

Cyclea barbata Miers leaf extract contains flavonoid compounds that have anti-inflammatory activity. This study aims to determine the effect of variations in citric acid and sodium bicarbonate concentrations on the physical properties of effervescent granules before (organoleptic, flow time, angle of repose, water content, and compressibility index test) and after (organoleptic, dissolve time, foam height, pH, and hedonic) reconstitution. Effervescent granules were formulated using the wet granulation method using varying concentrations of citric acid: sodium bicarbonate, respectively, it is FI (17%: 30%), FII (20%: 27%) and FIII (23%: 24%). Based on the results of the evaluation test of the physical properties of effervescent granules, FI and FII are appropriate for the requirements of each test, while FIII did not appropriate the requirements in the flow time, angle of repose, foam height and pH tests. This study concludes that FI (17%:30%) demonstrated the most optimal physical properties, meeting all evaluation parameters and receiving the highest hedonic score.
Uji Kualitas dan Identifikasi Sabun Padat Komersial Berbasis Lemak Hewan Menggunakan FTIR Pradini, Ni Komang Virginia; Salamah, Nina; Guntarti , Any; Nurkhasanah , Nurkhasanah
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1077

Abstract

Background: Solid soap is produced by saponification of fatty acids with strong bases, and its quality is influenced by the type of fat used. Objective: This study aims to evaluate the physical and chemical quality of solid soap made from beef tallow and lard and to identify compound profiles using Fourier Transform Infrared Spectroscopy (FTIR). Method: The methods include dry-rendering fat extraction, solid soap formulation, and soap quality tests (organoleptic properties, pH, moisture content, and foam height). FTIR analysis was conducted to compare the absorption spectra of each soap. Results: The results showed that soaps derived from both fat sources met all quality requirements specified in the Indonesian National Standard (SNI). FTIR analysis revealed generally similar spectral patterns; the lard solid soap exhibited a characteristic absorption band at approximately 3009 cm⁻¹, corresponding to =C-H stretching vibrations of unsaturated fatty acids. In contrast, this band was not detected in the solid soap made from beef tallow. In addition, the CH₂ rocking vibration around 720 cm⁻¹ was more pronounced in the beef tallow solid soap, indicating a higher proportion of long-chain saturated fatty acids. Conclusion: FTIR effectively identifies fat types and can be used in raw material authentication, especially in product halalness.
Potensi Interaksi Obat Pasien Penyakit Saraf di Rumah Sakit X Kabupaten Pidie Aceh: studi deskriptif kuantitatif Lubis, Salmah Handayani; Hasanah, Fenny; Siahaan, Desy Natalia; Intan, Cut
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1100

Abstract

Background: Drug interactions can increase the risk of side effects and reduce the success of therapy, especially in neurological patients who often receive polypharmacy. Objective: This study aims to determine the effect of administering a combination of drugs as a trigger for potential drug interactions based on their classification (minor, moderate, major) in patients with neurological diseases. Methods: This study is a retrospective quantitative descriptive study with a cross-sectional design. The sample consisted of outpatient neurological patients who received more than two drugs that met the inclusion criteria. Potential drug interactions were analyzed using the https://www.drugs.com/drug_interactions.html. Results: The highest category of drug interactions was moderate (n= 52; 75%) with the following drug combinations: (amlodipine and bisoprolol); (Simvastatin + Miconazole); (Simvastatin + Omeprazole); (Hydrochlorothiazide + Codeine); (Codeine + Amitriptyline). In addition, a major drug interaction category (n=28; 25%) was found in the administration of drug combinations (simvastatin and amlodipine) causing liver damage; (Alprazolam + Codeine); (Diazepam + Codeine); (Codeine + Gabapentin) each of these three drug interactions can cause CNS depression, (Furosemide + Gentamicin) causes additive nephrotoxicity and ototoxicity. Conclusion: Moderate-category interactions were the most common (amlodipine and bisoprolol). These drug interactions included pharmacodynamic interactions, and the combination of these drugs could cause clinical risks (hypotension, bradycardia). These findings indicate the need for pharmacists to perform clinical pharmacy services related to prescription review and drug therapy monitoring for patients receiving more than two drugs, as well as providing information to patients on the appropriate timing and dosage of their medications to avoid moderate and major drug interactions in neurological patients in hospitals.
Analisis Kadar Alkaloid Ekstrak Dan Fraksi Biji Trembesi (Samanea saman Merr.) Berdasarkan Kepolaran Pelarut Menggunakan Spektrofotometri UV-Vis Qolbi, Raihan Ahista; Al Azzahra, Yunita
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1101

Abstract

Samanea saman (Merr.) seeds are plant parts that have not been extensively studied, despite their potential as a source of bioactive compounds, particularly alkaloids. Alkaloid compounds are known to possess various pharmacological activities, such as antimicrobial, anticancer, and analgesic effects, making them promising candidates for the development of natural medicines. This study aimed to analyze the alkaloid content in the extract and fractions of S. saman seeds using solvents with different polarity levels,namely n-hexane (non-polar), ethyl acetate (semi-polar), and distilled water (polar). Extraction was carried out using the Ultrasound Assisted Extraction (UAE) method, while quantitative analysis of alkaloid content was performed using UV-Vis spectrophotometry with caffeine as the standard solution. Qualitative testing showed that the ethyl acetate and aqueous fractions were positive for alkaloids. Quantitative analysis of the extract revealed that S. saman seed extract contained alkaloids at a concentration of 142.59 mgCE/g extract. Further analysis of the fractions indicated that the ethyl acetate fraction had the highest alkaloid content 77.34 mgCE/g fraction, compared to the aqueous fraction 24.65 mgCE/g fraction and the n-hexane fraction 45.7 mgCE/g fraction. These findings suggest that semi-polar solvents are the most effective for extracting alkaloid compounds from S. saman seeds, thereby highlighting their potential for further development as raw materials for phytopharmaceuticals or natural-based herbal preparations.
Analisis Metanil Yellow Pada Minuman Sinom Di Surabaya Menggunakan Metode Spektrofotometri UV-Vis Pramushinta , IAK; Fitriyati , Irenia Ida; Ambawarwati , Nadya
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1131

Abstract

Background: Metanil yellow in food is very dangerous to human health. This is because this dye contains heavy metal residues that have been proven to cause cancer. Indonesian Minister of Health Regulation No. 239/Menkes/Per/V/85 prohibits the use of metanil yellow as a food dye, but this dye is often found in various markets. Objective: This study analyzed metanil yellow in sinom drinks circulating in the city of Surabaya. Methods: The analysis of metanil yellow dye included method validation using UV-Vis spectrophotometry on five samples of sinom drinks. Research Results: Theresults of the metanil yellow analysis in sinom drinks showed linearity with a regression of y = 0.0191x – 0.1774, an r2 value of 0.9961, an LOD of 1.30833 ppm, and an LOQ value of 4.36108 ppm. The precision value was RSD 1.19%. Accuracy values with average % recovery of 94.26% (80%), 94.66% (100%), and 92.91% (120%). In the analysis of metanil yellow from 5 samples circulating in the southern part of Surabaya, code C 0.001854%, west code A 0.002475%, center code C 0.001725%, east code B 0.001249%, and north code A 0.002823%. Conclusion: The UV-Vis spectrophotometry method has been validated and meets the requirements for preliminary screening analysis of metanil yellow. Preliminary screening results of five samples of sinom drinks circulating in the city of Surabaya showed indications of metanil yellow in all samples with concentrations ranging from 12.41 to 28.28 ppm. Due to the limited specificity of the UV-Vis spectrophotometry method, this study needs to be confirmed with more specific techniques such as HPLC or TLC to ensure the identity of the metanil yellow compound.
Hubungan Karakteristik Pasien dengan Kepatuhan Minum Obat pada Pasien Hipertensi Berdasarkan Skala MMAS-8 Apriani, Aida; Sirait , Tri Susanti; Silitonga , Desni Rinanda; Zawita, Zawita
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1153

Abstract

Background: Hypertension is classified as a non-communicable disease with a relatively high prevalence and poses a significant risk of various complications if not properly managed or controlled. Medication adherence plays a crucial role in determining the success of antihypertensive therapy. Objective:This study aimed to analyze the level of medication adherence among hypertensive patients at Pidie Jaya General Hospital using the Morisky Medication Adherence Scale (MMAS-8) instrument. Methods:This research employed a descriptive-analytic design with a cross-sectional approach involving 98 hypertensive patients selected using the Slovin formula. Data were collected using the MMAS-8 questionnaire and analyzed using the Chi-square test with a significance level of p < 0.05. Results:The findings showed that medication adherence among respondents was categorized as adherent (26.5%), moderately adherent (58.2%), and non-adherent (15.3%). There were no significant associations between adherence and sex, age, education, occupation, duration of treatment, number of medications, or family support (p > 0.05). However, a significant relationship was found between medication adherence and the distance from the patient's residence to the healthcare facility (p = 0.001). Conclusion: Distance to treatment affects the level of compliance of hypertensive patients with medication. Therefore, strategies are needed to improve access to healthcare services, including optimizing clinical pharmacy services to monitor patient compliance.

Page 66 of 70 | Total Record : 698

 64   65   66   67   68 

Filter by Year

2018 2026


Reset
Filter By Issues
All Issue JPS Volume 9 Nomor 1 (2026) JPS Volume 8 Nomor 4 (2025) JPS Volume 8 Nomor 3 (2025) JPS Volume 8 Nomor 2 (2025) JPS Volume 8 Nomor 1 (2025) JPS Volume 7 Nomor 4 (2024) JPS Volume 7 Nomor 3 (2024) JPS Volume 7 Nomor 2 (2024) JPS Volume 7 Nomor 1 (2024) JPS Volume 6 Nomor 4 (2023) JPS Volume 6 Nomor 3 (2023) JPS Volume 6 Nomor 2 (2023) JPS Volume 6 Nomor 1 (2023) Suppl. 1, No. 1 (2023) JPS Volume 1 Nomor 1 (2018) More Issue