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Journal of Pharmaceutical and Sciences.
Published by Universitas Tjut Nyak Dhien
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490/journal-jps.com
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 654 Documents
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Pelayanan Farmasi untuk Daerah Tertinggal, Terdepan, dan Terluar (3T) Terkait Program Penyakit HIV Berdasarkan Integrasi Model Pemberi Layanan yang Terdiferensiasi (PLD): Sebuah Tinjauan Sistematis Renaldi, Fransiskus Samuel; Pangeran, Khrisna
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1331

Abstract

Background: Differentiated Service Delivery (DSD) has been proposed to improve HIV treatment continuity in remote areas; however, its success depends on the integration of systemic supports. Objective: This review synthesizes evidence on the effectiveness of community-based DSD models and the determinants of their success in underdeveloped, frontier, and outermost (3T) areas, particularly concerning supply chain resilience, quality assurance, and aligned governance and financing. Methods: A systematic review with narrative synthesis was conducted following PRISMA guidelines. Literature searches were performed in PubMed, Scopus, Web of Science, and grey literature repositories (2010–2025). Out of 1,520 records, 32 studies met the inclusion criteria. Results: Community-based DSD models (ART groups, MMD) were effective in improving adherence, retention, and reducing visit burden. This success was strongly determined by: (1) ARV supply chain stability (minimal stock-out days, synchronization with MMD schedules); (2) quality assurance in storage–distribution (temperature control, FEFO); and (3) aligned governance and financing (pharmacist roles, community health worker incentives, last-mile funding). Qualitative findings identified service proximity, confidentiality, and logistical reliability as key facilitators. Conclusion: DSD is a systemic intervention whose effectiveness hinges on multidimensional readiness. Strengthening HIV pharmaceutical services in 3T areas requires an integrated approach that simultaneously builds supply resilience, service quality, and adaptive governance. This review proposes operational indicators and a phased implementation roadmap for contextual adaptation.
Formulasi dan Uji Efektivitas Ekstrak Bayam Duri (Amaranthus spinosus L.) Sebagai Krim Antibakteri Terhadap Bakteri Cutibkterium acnes dan Staphylococcus aureus Daulay, Anna miroh; Rasyidah, Rasyidah
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1332

Abstract

Acne vulgaris is a common skin problem in adolescents that often causes stress, anxiety, and decreased self confidence. Spiny Amaranth (Amaranthus spinosus L.) has antibacterial potential, but its effectiveness against Cutibacterium acnes has not been fully explored. This study aims to develop a cream formulation of Spiny Amaranth leaf ethanol extract and test its antibacterial effectiveness against Cutibacterium acnes and Staphylococcus aureus. The research method includes extraction of Spiny Amaranth leaves, cream preparation, and antibacterial activity test using the disc diffusion method. The results showed that the antibacterial cream of Spiny Amaranth leaf extract has good effectiveness against the growth of Cutibacterium acnes and Staphylococcus aureus, with an increasing inhibition zone along with the increase in extract concentration, namely 18.5 mm at 25% concentration and 27.9 mm at 50% concentration for Cutibacterium acnes, and 16.0 mm at 25% concentration and 23.3 mm at 50% concentration for Staphylococcus aureus. The characteristics of the cream that are suitable for the skin and the stable emulsion type make this cream ideal for skin application. The results of this study indicate that the antibacterial cream of Spiny Amaranth leaf extract can be used as an effective alternative natural antibacterial treatment.
Analisis Kontaminasi DNA Babi (Sus scrofa domesticus) Pada Produk Olahan Bakso Sapi Dan Ayam di Tuntungan, Sumatera Utara Sandika , Febri; Idami, Zahratul; Idris, Muhammad
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1374

Abstract

Background: Meatballs are a popular processed meat product in Indonesia. High consumption of meatballs is accompanied by increasing public concern, especially among Muslims, regarding the halal aspect of the product. The potential contamination of pork DNA (Sus scrofa domesticus) in beef and chicken meatballs is a critical issue, whether due to unintentional cross-contamination or adulteration. Tuntungan area, North Sumatra, with its diverse demographic and trading characteristics, is an important location to assess the level of contamination. Objective: This study aimed to detect the presence of pork DNA (Sus scrofa domesticus) contamination in processed beef and chicken meatball products traded in the Tuntungan area, North Sumatra. Methods: Four meatball samples (three chicken meatballs and one beef meatball) were collected from street vendors and meatball stalls at different locations. DNA detection was performed molecularly using the Real-Time Polymerase Chain Reaction (qPCR) method with the *Genechecker UF-300* instrument. The procedure began with sample preparation, DNA extraction using the Genolution tool, master mix preparation, and analysis using the PCR Gen Checker chip. Result validation was based on the Cycle threshold (Ct) value in the target channel (FAM for pork DNA) and the internal control channel (ROX). Results: The analysis results of all four samples showed a FAM Ct value of 0 (not detected), indicating no amplification of specific pork target DNA. Meanwhile, the ROX Ct value (internal control) in all samples was detected in the range of 19.41–20.50, proving that the DNA extraction and amplification process ran optimally without inhibition. The positive control showed valid amplification signals, and the negative control showed no contamination. Conclusion: Based on the molecular detection results, it can be concluded that all tested beef and chicken meatball samples from the Tuntungan area were not contaminated with pork DNA (Sus scrofa domesticus). This finding indicates that traders in the area have applied good processing practices and separated raw materials, so the meatballs sold meet the halal aspect in terms of ingredient authenticity.
Determinan Kepatuhan Pasien Tuberkulosis Paru Dalam Menjalani Pengobatan di UPT. Puskesmas Simalingkar Tahun 2024 Barus , Nanda Isabel; Manurung, Kesaktian; Hutajulu , Johansen; Wandra , Toni; Girsang , Vierto Irennius
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1386

Abstract

Background: Pulmonary tuberculosis (TB) is a chronic infectious disease that remains a major global and national public health problem, with Indonesia ranking second among countries with the highest TB burden worldwide. Non-adherence to treatment is one of the main barriers to successful TB control, as it may lead to treatment failure, drug resistance, and increased morbidity and mortality. At the Simalingkar Community Health Center (UPT Puskesmas Simalingkar), the specific factors determining treatment adherence among pulmonary TB patients have not been extensively studied. Objective: This study aimed to analyze the determinants of treatment adherence among pulmonary tuberculosis patients at the Simalingkar Community Health Center in 2024. Methods: This study employed an analytical cross-sectional design. The study population consisted of all pulmonary TB patients undergoing treatment at the Simalingkar Community Health Center, with a total sample of 90 respondents selected using a total sampling technique. Data were collected through questionnaires and medical records, and analyzed using univariate, bivariate (Chi-square test), and multivariate (logistic regression) analyses, with a significance level of p < 0.05. Results: A total of 77.8% of patients were adherent to treatment. Bivariate analysis showed significant associations between education (p < 0.001), employment status (p = 0.004), knowledge (p = 0.006), and health care services (p = 0.011) with treatment adherence. Age, sex, and family support were not significantly associated with adherence. Multivariate analysis indicated that the most dominant factor associated with treatment adherence was educational level (OR = 9.004; 95% CI: 2.58–31.49), followed by employment status (OR = 5.59; 95% CI: 1.48–21.12), and health care service support (OR = 3.99; 95% CI: 1.09–14.56). Conclusion: The significant determinants of treatment adherence among pulmonary TB patients at the Simalingkar Community Health Center were educational level, employment status, and health care service support, with education being the most dominant factor. It is recommended that TB control programs place greater emphasis on interventions aimed at improving health literacy, socio-economic support, and the quality and accessibility of health care services to enhance treatment adherence.

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