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INDONESIA
JOURNAL OF Mother and Child Health Concerns
Published by Indonesian Public Health-Observer Information Forum
ISSN : 27984095     EISSN : 27984192     DOI : 10.56922
Core Subject : Health,
Health Professions Nursing Public Health
Berisi kumpulan karya ilmiah dari peneliti diberbagai perguruan tinggi di Indonesia, khususnya di bidang kesehatan ibu dan anak yang berdasarkan kepada kebutuhan pasien secara total meliputi: kebutuhan fisik, emosi, sosial, ekonomi dan spiritual. Adapun penelitiannya mencakup 4 aspek pokok, yakni: promotif, preventif, kuratif, dan rehabilitatif. Terbit 2 kali dalam satu tahun bulan Juni dan Desember
Arjuna Subject : Keperawatan - Maternity and Midwifery
Articles 242 Documents
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Shifting the paradigm to letrozole as first-line ovulation induction in pcos: a review of efficacy and safety Janu, Juwana; Haryani, Reny
THE JOURNAL OF Mother and Child Health  Concerns Vol. 5 No. 1 (2026): April Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Persatuan Perawat Nasional Indonesia (PPNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/mchc.v5i1.3084

Abstract

Background: Polycystic ovary syndrome (PCOS) is a primary cause of anovulatory infertility. While clomiphene citrate (CC) has been the traditional treatment, letrozole (LE) has emerged as a superior alternative with better clinical outcomes. Purpose: to evaluate the clinical efficacy, safety, and biological mechanisms of LE compared with CC in ovulation induction for PCOS patients. Method: A comprehensive literature search was conducted on PubMed and Google Scholar for studies published between 2021 and 2026. Seven high-quality articles, including randomized controlled trials (RCTs) and meta-analyses, were selected for synthesis. Results: The synthesis of the literature indicates that LE significantly increases the live birth rate by 54% (RR 1.54) and improves ongoing pregnancy rates compared with CC. LE is more efficient, showing a shorter time to ovulation (17.2 vs 24.1 days) and higher success in obese patients (BMI > 30). Mechanistically, LE superiorly enhances endometrial receptivity by significantly increasing Integrin αvβ3 and VEGF expression, as well as the Endometrial Flow Index (FI). Furthermore, LE demonstrates a superior safety profile with a 58% lower risk of multiple pregnancies and minimal incidence of ovarian hyperstimulation syndrome (OHSS). Conclusion: Letrozole is more effective and safer than CC, primarily due to its beneficial impact on the endometrial microenvironment. LE could be implemented as the universal first-line treatment for infertility in women with PCOS. Suggestion: For clinicians, LE can be considered as the universal first-line therapy for ovulation induction in patients with PCOS, replacing CC. From a health service policy perspective, standard protocols in fertility clinics need to be updated to integrate LE use in order to improve pregnancy success and reduce long-term costs due to complications of multiple pregnancy
Effectiveness of oxytocin massage on breast milk production in postpartum mothers Lina, Anastasia; Pramulya, Asmaurina; Kalista, Efrosina Ludovika; Astuti, Agnes Dwiana Widi; Sera, Anjelina; Firmatary, Odilya
THE JOURNAL OF Mother and Child Health  Concerns Vol. 5 No. 1 (2026): April Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Persatuan Perawat Nasional Indonesia (PPNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/mchc.v5i1.3118

Abstract

Background: The postpartum period is a crucial period in a mother's life after childbirth, as it involves significant physical and emotional recovery. One of the main causes of postpartum morbidity is breastfeeding problems due to low milk production. Based on the 2023 Indonesian Health Profile from the Ministry of Health, only around 65.5% of mothers successfully breastfeed exclusively for the first six months. Breastfeeding is considered the best method to provide necessary nutrition, which has benefits not only for the mother's health but also for the optimal growth and development of the child. Oxytocin massage therapy is a massage that aims to stimulate the hormone oxytocin. This technique is effective in increasing milk production and release, providing relaxation, reducing stress, and increasing the bond between mother and baby. Purpose: To identify breast milk production in postpartum mothers using oxytocin massage. Method: This experimental study used a post-test control group design. The population was 36 postpartum mothers within 3 hours of delivery. Through purposive sampling, 24 postpartum mothers were selected as respondents, divided into 12 in the intervention group and 12 in the control group. The measurement instrument used was an observation questionnaire on breast milk production, which measured the newborn's urine volume over a 24-hour period (normally 6-8 times a day). A urine volume of 30-50 mg was categorized as good and a urine volume of less than 29 mg was ≥ inadequate. The intervention consisted of oxytocin massage given to postpartum mothers 3 hours postpartum, every morning and evening, for 3 days. Data were analyzed using the Wilcoxon test to determine the effect of oxytocin massage on breast milk production. Results: The average age of respondents was 27.63 years with a standard deviation of ±4.29 years with the majority of respondents being in the 26-30 years age range of 45.8%. Most of the respondents' education level was junior high school, namely 41.7%, and the majority of respondents had a job status as a housewife, namely 62.5%. Based on the Wilcoxon test, pValue=0.02 was obtained, where for the intervention group, those classified as less were 16.7% and those in the good category were 83.3%. While for the control group, those classified as less were 66.7% and those in the good category were 33.3%. Conclusion: Oxytocin massage intervention has an effect on increasing breast milk production in postpartum mothers. Oxytocin massage has been proven effective in increasing breast milk production and shows a significant difference in breast milk volume after oxytocin massage, where breast milk production increases to a greater or smoother flow, thereby ensuring adequate breast milk supply for the baby. Suggestion: It is recommended that health facilities or community cadres educate the public regarding the understanding and benefits of oxytocin massage. This increased public knowledge will contribute to the implementation of early nutritional adequacy programs for toddlers as an effort to prevent stunting.

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