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INDONESIA
Jurnal Sains Farmasi dan Kesehatan
Published by CV ITTC Indonesia
ISSN : -     EISSN : 30249368     DOI : 10.47233/jfkes
Core Subject : Health, Science,
Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary
Jurnal Sains Farmasi dan Kesehatan (JFKES) E-ISSN : 3024-9368 is an open access journal which is a media of research publication and review article on all aspects of pharmaceutical science that is innovative, creative, original and based on scientific. Articles published in this journal include Pharmaceutical Technology, Pharmacology, Pharmaceutical Chemistry, Traditional Medicine, Food and beverages, and the field of public health
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 157 Documents
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Kemajuan Sistem Penghantaran Obat Sublingual: Formulasi, Karakteristik, Farmakokinetik, dan Aplikasi Klinis Shelsabila Dhea Liffany; Ba’dhiva Yusviar Novia; Nafrila Raheny Sulistyowati; Elisyah Alya Azarina; Silvi Indi Ningsih; Dewi Rahmawati
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4922

Abstract

Sublingual drug delivery systems have attracted significant attention in modern pharmaceutical technology due to their ability to provide rapid therapeutic effects and bypass first-pass metabolism in the liver. This review article aims to synthesize the relevance of several recent studies on the development of sublingual tablets, including formulation aspects, physicochemical properties, pharmacokinetic parameters, and clinical safety evaluation. Based on literature analysis of various original articles, sublingual tablets have proven to be highly effective for the management of acute conditions such as severe pain (using Sufentanil), angina pectoris (using Nitroglycerin), and motion sickness (using Promethazine HCl), as well as optimal for nutritional supplementation (Cyanocobalamin) and allergy immunotherapy in pediatric populations. The integration of modern excipient technologies, including the use of superdisintegrants and mucoadhesive polymers, plays a crucial role in determining the dissolution profile, systemic bioavailability, and patient comfort. Overall, this article provides an integrative view on how optimization of direct-freezing sublingual formulations contributes to safe and efficient clinical therapeutic success.
Hubungan Dukungan dan Koping Keluarga Dengan Tingkat Kekambuhan Pada Pasien Skizofrenia di Wilayah Kerja Puskesmas Lubuk Buaya Padang tahun 2025 Riza Anatul Fausia; Edo Gusdiansyah; Amelia Susanti
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4926

Abstract

The prevalence of schizophrenia affects approximately 24 million people, or 1 in 300 (0.32%) worldwide. The number of schizophrenia patients in Indonesia increased from 1.7% in 2013 to 7% in 2018. In 2023, West Sumatera ranked eighth in Indonesia with 39.1% of the population suffering from mental disorde. The purpose of this study was to determine the relationship between family support and coping with relapse rates in schizophrenia patients in the Lubuk Buaya Padang Community Health Center working area in 2025. This was an analytical study with a cross-sectional design. The study was conducted from March to August 2025. Data collection was conducted over a 10-day period, from June 11 to 21, 2025. The population of all families with schizophrenia in the Lubuk Buaya Padang Community Health Center working area was 234, with a sample size of 70 individuals. The sampling technique was proportional random sampling. The study used a questionnaire and interviews. Data were analyzed univariately and bivariately using the Chi-Square statistical test. The results showed that less than half (48.6%) of schizophrenia patients had a high relapse rate. Less than half (47.1%) had a supportive family. Less than half (48.6%) of respondents reported family coping skills in schizophrenia patients. There was a relationship between family support and coping with the relapse rate of schizophrenia patients in the Lubuk Buaya Padang Community Health Center (p-value = 0.000). The conclusion is that there is a relationship between family support and family coping and relapse in schizophrenia patients. It is hoped that psychiatric nurses can provide education through leaflets to families about proper home care for mental patients to prevent schizophrenia relapse in family caregivers..
Hubungan Dukungan Keluarga Dengan Motivasi Pasien Hipertensi Dalam Memeriksakan Tekanan Darah Di Puskesmas Belimbing Padang Tahun 2025 Ayu Tania Putri
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4932

Abstract

The incidence of hypertension in the carambola Health Center in 2024 is 8000 cases. The incidence of hypertension in Puskesmas Belimbing in the last three months as many as 761 cases with hypertension patients at the age of 25-59 years as many as 200 people. Many people with hypertension currently do not control blood pressure to health facilities, because there is no support from the family in responding to the patient's need to run an examination. The purpose of this study was to determine the relationship of family support with the motivation of hypertensive patients in checking blood pressure in Puskesmas Belimbing Padang. This type of research is descriptive analytic with cross sectional study. This research was conducted at Puskesmas Belimbing Padang. Research time is in January to August 2025. Data collection was carried out in August 2025. The population in this study were all hypertensive patients in Puskesmas Belimbing Padang in the last three months as many as 200 people with a sample of 67 people. Sampling technique is accidental sampling. Data analysis using statistical analysis of Chi-Square test results. The results showed that 53.7% of respondents had poor motivation and 55.2% of respondents had poor family support. There is a relationship between family support and the motivation of hypertensive patients in checking blood pressure at the Belimbing Padang Health Center in 2025 with a p-value= 0.000. There is a significant relationship between family support with the motivation of hypertensive patients in checking blood pressure. Through the leadership of Puskesmas Belimbing, the results of this study are expected to be used as input for health workers in preventing complications of hypertension through counseling on motivation to check blood pressure in hypertensive patients.
Hubungan Pola Asuh Orang Tua Dengan Kejadian Speech Delay Pada Anak Prasekolah Usia 3-6 Tahun Di Wilayah Kerja Puskesmas Dadok Tunggul Hitam Kota Padang Sisila Kencana; Sari Indah Kesuma; Rischa Hamdanesti
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4940

Abstract

Speech delay in preschool children is a developmental problem that can hinder communication, social interaction, and academic readiness in the future. The prevalence of speech delay is reported to be relatively high both globally and in Indonesia, with various risk factors such as genetics, nutritional status, excessive use of gadgets, and parenting style. This study aimed to determine the relationship between parenting styles and the incidence of speech delay among preschool children aged 3–6 years in the working area of Dadok Tunggul Hitam Health Center, Padang City. This study employed a quantitative method with a cross-sectional design. The population consisted of 69 children, and a sample of 41 children was selected using purposive sampling according to the inclusion criteria. The independent variable was parenting style, while the dependent variable was the incidence of speech delay. Data were collected using a parenting style questionnaire and a language development assessment based on a modified Denver II test. Data analysis was carried out using univariate and bivariate approaches with the Chi-Square test. The results showed that the authoritarian parenting style was most commonly applied (48.8%), The incidence of speech delay was found in 53.7% of children. The Chi-Square test obtained a p-value of 0.000 (p < 0.05), indicating a significant relationship between parenting style and the incidence of speech delay. The democratic parenting style was proven to better support language development compared to authoritarian and permissive styles. In conclusion, appropriate parenting, particularly the democratic style that emphasizes communication and stimulation, plays an important role in preventing speech delay. It is recommended that parents increase verbal interaction, limit gadget use, and actively provide early language stimulation.
Pengaruh Brain Gym Terhadap Perubahan Nilai Fungsi Kognitif Pada Lansia Demensia Di Panti Sosial Tresna Werdha Sabai Nan Aluih Sicincin Padang Pariaman 2025 Suci Rahayu; Eri Wahyudi; Helmanis Suci
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4941

Abstract

The prevalence of dementia is estimated at 55 million people suffering from dementia in the world. Indonesia is estimated to have 1.2 million people. Dementia is common in the elderly. Elderly people with dementia have an impact on becoming more withdrawn and unable to control their behavior. Their moods often change and they like to walk around (wander). In the elderly, decreased brain and body abilities make the body susceptible to illness, dementia and frustration. The purpose of this study was to determine the effect of brain gym on changes in cognitive function scores in elderly with dementia at the Sabai Nan Aluih Sicincin Padang Pariaman Social Home. The method in this study was quantitative with a pre-experimental design, one group pretest-posttest approach. The study was conducted at the Sabai Nan Aluih Sicincin Padang Pariaman Social Home. The population of all elderly people with cognitive disorders at the Sabai Nan Aluih Sicincin Padang Pariaman Social Home was 40 people with a sample of 15 people. The sampling technique was purposive sampling. Data were collected using a questionnaire. Univariate and bivariate data analysis used the Paired Sample T-Test. The results of the study showed that the average cognitive function score before brain gym was 14.40. The average cognitive function score after brain gym was 25.47. There is an effect of brain gym on changes in cognitive function values ​​in elderly with dementia at the Tresna Werda Sabai Nan Aluih Sicincin Padang Pariaman Social Home in 2025 (p value = 0.000). The conclusion of this study is that there is an effect of Brain Gym on changes in cognitive function values ​​in elderly with dementia. It is hoped that through the leadership of the Tresna Werdha social home, Brain Gym can be made a routine activity for the elderly.
Artificial Intelligence (AI) Dalam Manajemen Farmasi dan Pelayanan Kefarmasian Zakkiya Sabilla; Zahratul Humaidah; Elsa Tectona Zulianti; Renata Setya Agustin; Rizka Tri Amanda Hidayat; Namira Salsabillah; Firlia Nur Afifah; Alvan Andika Permadani; Rachma Hanifah
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4942

Abstract

The development of Artificial Intelligence (AI) has significantly transformed pharmaceutical services by improving efficiency, accuracy, and decision-making quality. This journal review aims to analyze the development of AI implementation in pharmacy services, compare research methods, and identify its benefits, limitations, and future opportunities. The method used was a Narrative Literature Review of ten scientific articles published between 2023 and 2026, collected from databases such as Google Scholar, PubMed, ScienceDirect, SpringerLink, and IEEE Xplore. The review found that AI technologies, including Machine Learning, Artificial Neural Networks, Natural Language Processing, Blockchain, Cloud Computing, and Predictive Analytics, can improve the accuracy of drug demand forecasting, reduce medication errors, optimize inventory management, and support clinical pharmacy services. However, most studies still focus on model development or simulations, so real-world implementation in pharmacy practice remains limited. Overall, AI has strong potential to support the digital transformation of pharmacy services, although further validation and readiness of human resources are still needed.
Formulasi dan Uji Face Mist Anti Jerawat Ekstrak Kemangi dan Pepaya Elmi Sariani Hasibuan; Ulma Sintia; Ira Nova Siregar
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4955

Abstract

Acne vulgaris is a common skin disorder caused by several factors, one of which is infection by Propionibacterium acnes. The prolonged use of antibiotics may lead to bacterial resistance; therefore, safer natural-based alternatives are needed. Basil leaves (Ocimum basilicum L.) and papaya leaves (Carica papaya L.) contain secondary metabolites such as flavonoids, alkaloids, saponins, tannins, and essential oils that exhibit antibacterial activity. This study aimed to formulate a face mist containing a combination of basil leaf and papaya leaf extracts and to evaluate its physical quality and antibacterial activity against Propionibacterium acnes. This experimental study prepared four formulations: F0 (without extract), F1 (1 g basil leaf extract and 1 g papaya leaf extract), F2 (2 g and 2 g), and F3 (3 g and 3 g). The physical evaluations included organoleptic properties, pH, spray spreadability, and drying time. Antibacterial activity was determined using the agar diffusion method by measuring the diameter of the inhibition zone. The results showed that all formulations exhibited acceptable physical characteristics, with pH values ranging from 6.23 to 6.45, spray spreadability from 8.6 to 9.3 cm, and drying time from 3.19 to 5.14 minutes. Increasing the extract concentration tended to decrease spray spreadability and prolong the drying time. The antibacterial assay demonstrated that F3 exhibited the highest antibacterial activity with an average inhibition zone diameter of 12 mm (strong category), followed by F2 with 8 mm (moderate category) and F1 with 4 mm (weak category), while the positive control produced an inhibition zone of 15 mm. In conclusion, the combination of basil leaf and papaya leaf extracts can be successfully formulated into a face mist that meets the required physical quality standards and exhibits antibacterial activity against Propionibacterium acnes, with F3 identified as the optimum formulation.

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