cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Irena Sutanto
Contact Email
smjournal@uhamka.ac.id
Phone
+6281290749109
Journal Mail Official
editorsmj@uhamka.ac.id
Editorial Address
Fakultas Kedokteran, Universitas Muhammadiyah Prof. DR. HAMKA, Jl. Raden Fatah No.01, RT.002/RW.006, Parung Serab, Kec. Ciledug, Kota Tangerang, Banten 13460
Location
Kota adm. jakarta timur,
Dki jakarta
INDONESIA
Sanus Medical Journal
Published by Universitas Muhammadiyah Prof. Dr. Hamka
ISSN : -     EISSN : 2745868     DOI : https://doi.org/10.22236/sanus
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Sanus Medical Journal is a peer-reviewed medical and health journal published periodically every six months. Sanus Medical Journal publishes descriptive, analytical, and experimental studies, reviews, systematic reviews, case reports, letters, and editorials in the fields of Medicine, Health, Medical and Health Education, and Islamic Medicine. The scope of Sanus Medical Journal goes beyond the boundaries of discussions in the fields of clinical medicine and health in general, by providing new insights into etiologies, determinants, distribution, management and prevention of diseases in individuals and communities. Sanus Medical Journal attempts to meet the demands of rapid developments in information and medical and health research by committing to reduce the range of online publications to around six weeks after the submission of a manuscript. Articles will be published online in advance, and the printed version included in the next scheduled edition. Sanus Medical Journal will continue to strive to improve its scientific reputation by publishing quality articles reviewed by experts who are highly competent in their respective fields. Sanus Medical Journal greatly appreciates the contributions of authors from related disciplines. Manuscripts can be sent via email to: smjournal@uhamka.ac.id or via the website https://journal.uhamka.ac.id/index.php/smj.
Arjuna Subject : Kedokteran - Farmakologi (Medis)
Articles 89 Documents
 1   2   3   4   5 
Gambaran Quantitative Electroencephalography (QEEG) Anak Laki-laki Penderita Attention-Deficit Disorder (ADD) Gea Pandhita S; Sri Sutarni
Sanus Medical Journal Vol. 2 No. 1 (2021): Vol. 2 No. 1 (2021): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v1i1.6610

Abstract

Background. The Diagnostic and Statistical Manual of Mental Disorders (DSM) grouping the types of ADD is based on the clinical symptoms of neurobehavioral disorders, regardless of the possible underlying etiology. This means that the same ADD type group may have a different etiology of functional brain disorders. Meanwhile, QEEG has been known to describe the possible etiology that underlies an ADD event. This study aims to identify differences in QEEG features in the same ADD type group. Methods. Subjects consisted of 40 boys with ADD. QEEG was recorded from 21 sites, and Fourier transformed to provide estimates for relative power in the delta, theta, alpha, and beta bands in the frontotemporal and central regions. These data were converted to Z-scores based on the normal value data; afterward, they were subjected to cluster analysis. Independent sample t-tests were used to determine how the total ADD group and the ADD cluster subgroups differed from the normal value. Results. The total ADD group had increased relative delta (Z-score-frontotemporal region = 3,26 ± 1,59; Z-score-central region = 4,04 ± 1,71), decreased relative alpha (Z-score-frontotemporal region = -2,78 ± 1,29; Z-score-central region = -2,86 ± 1,36), decreased relative beta (Z-score-frontotemporal region = -5,33 ± 1,61; Z-score-central region = -6,19 ± 1,86), increased rasio teta/alpha (Z-score-frontotemporal region = 2,806 ± 1,41; Z-score-central region = 2,59 ± 1,26), and increased rasio teta/beta (Z-score-frontotemporal region = 4,36 ± 1,69; Z-score-central region = 4,94 ± 1,46). Two distinct QEEG clusters subgroups were found. The first cluster was characterized by increased central relative delta (Z-score-central region = 3,02 ± 1,17), decreased relative beta (Z-score-frontotemporal region = -4,29 ± 0,73; Z-score-central region = -5,06 ± 1,19) and increased rasio teta/beta (Z-score-frontotemporal region = 3,83 ± 1,91; Z-score-central region = 4,94 ± 1,96). The second cluster was characterized by increased relative delta (Z-score-frontotemporal region = 4,71 ± 1,02; Z-score-central region = 5,72 ± 0,98), decreased relative alpha (Z-score-frontotemporal region = -3,92 ± 1,12; Z-score-central region = -4,24 ± 0,69), decreased relative beta (Z-score-frontotemporal region = -7,08 ± 1,06; Z-score-central region = -8,09 ± 0,99), increased rasio teta/alpha (Z-score-frontotemporal region = 3,08 ± 1,04; Z-score-central region = 2,86 ± 1,02), and increased rasio teta/beta (Z-score-frontotemporal region = 5,23 ± 1,16; Z-score-central region = 5,71 ± 1,35) Conclusions. These results indicate that boys with ADD do not constitute a homogenous group in QEEG profile terms. Two distinct QEEG clusters were found. The first cluster was typified by a cortically hypoaroused, while the second cluster was typified by a maturational-lag in central nervous system development. This difference in possible etiology may have implications for studies of the utility of QEEG in the diagnosis of ADD and the differences in therapeutic response between the two groups.
PULMONARY EMBOLISM WITH ANTIPHOSPHOLIPID SYNDROME: A CASE REPORT Sidhi Laksono Purwowiyoto; Ferel M; Yeria R; Reynaldo Halomoan; Kurniawan
Sanus Medical Journal Vol. 2 No. 2 (2021): Vol. 2 No. 2 (2021): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v2i2.7256

Abstract

Antiphospolypid sí­ndrome (APS) is a systemic autoimmune condition that is related to vascular thrombosis. Patients with APS are at risk for developing pulmonary embolism (PE) events. In this case, we present a 68 years old female with complaints of sudden onset of persistent shortness of breath for two days. No past medical history was identified. Physical and diagnostic examination revealed the presence of PE and antiphospolipid antibodies. Diagnosis of PE and APS were made. Patients then received initial anticoagulant using enoxaparin subcutaneously. Initial anticoagulants in patients with APS and PE should be administered. However, it is important to choose the right anticoagulant. DOAC is contraindicated due to the increased risk of thromboembolic events.
Gambaran Hematologi pada Defisiensi Vitamin B12 Irena Ujianti
Sanus Medical Journal Vol. 2 No. 2 (2021): Vol. 2 No. 2 (2021): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v2i2.7327

Abstract

Background and Aims. Anemia is a condition when the number of red blood cells or hemoglobin is lower than the normal number. The main cause of anemia is a lack of factors for the formation and maturation of red blood cells. Vitamin B12 plays a role in the synthesis and maturation of red blood cells, a lack of this vitamin will cause the formation and maturation of red blood cells to be disrupted. Method. This was an experimental animal study with twelve rats with frederer's family. The rat was fed a Vitamin B12 Deficient Diet for 16 weeks as the treatment group and standard diet as the control group. Vitamin B12 in the liver was analyzed in rats for 16 weeks. Hemoglobin and MCV were analyzed in plasma for 16 weeks. Results are expressed as means of control, and test animals were established by ANOVA using SPSS 20.0 software Results. In the present study, we found that liver vitamin B12 level was decreased in treatments groups compares to the positive control group at sixteen weeks (p<0.01). Hemoglobin was decreased in the treatment group compare positive control group at sixteen weeks (p<0.001). Mean Corpuscular Volume (MCV) was increased in the treatment group's compare positive control group at sixteen weeks (p<0.01) Conclusions. Our findings demonstrate that vitamin B12 deficiency decreased hemoglobin and increased MCV.
Difficulties Differentiating Between Basal Cell Carcinoma and Trichoepithelioma: A Case Report Zahra Nurusshofa; irena ujianti
Sanus Medical Journal Vol. 2 No. 2 (2021): Vol. 2 No. 2 (2021): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v2i2.7371

Abstract

Background. Basal cell carcinoma (BCC) is the most common type of malignant skin tumor with basal cell differentiation. Trichoepithelioma (TE), however, is a rare benign skin tumor with follicular differentiation. Both types of tumor have commonalities in terms of clinical and histopathological features. Some cases, in fact, require ancillary studies to distinguish between the two. Confusing the two tumors may result in different future outcomes for the patient, due to their vastly different prognoses and treatments. This case report outlines two different cases, and discusses how to distinguish between the two types of tumor without the use of an ancillary study.Method. We examined the cases of one patient with basal cell carcinoma and one patient with trichoepithelioma, comparing their clinical manifestations and characteristic histological features.Results. Trichoepithelioma and BCC share several overlapping histopathological features. Trichoepithelioma and BCC share several overlapping histopathological features. The TE in this case report also exhibited a nodular pattern, connection to the epidermis, stromal cleft, and prominent nuclear palisading, which are more commonly found in BCC. However, scanty mitotic activity, the presence of non-atypia cells, and symmetry of the lesion, are favor TE.Conclusion. Differentiation between BCC and TE is only possible using cytomorphological assessment with a high-power field of view.
PENATALAKSANAAN KOMPREHENSIF LANSIA DENGAN PENURUNAN FUNGSI KOGNITIF DAN DEMENSIA Gea Pandhita S; Purwita W Laksmi; Erlina Marfianti
Sanus Medical Journal Vol. 2 No. 2 (2021): Vol. 2 No. 2 (2021): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v2i2.7430

Abstract

Pasien Geriatri mempunyai karakteristik yang khusus, berbeda dengan karakteristik pasien pada golongan usia yang lain. Pasien geriatri antara lain ditandai dengan karakteristik memiliki multi-morbiditas atau multi-penyakit, kapasitas fisiologis yang menurun, manifestasi klinis penyakit yang tidak khas, status fungsional menurun, dan malnutrisi. Kondisi ini akan menimbulkan masalah kesehatan spesifik yang lazim ditemui pada pasien geriatri, yaitu: Frailty, Sarkopenia, Delirium, Jatuh, Gangguan Tidur, Dizziness, Syncope, Ulkus Dekubitus, Inkontinensia, dan Elder mistreatment. Beberapa masalah kesehatan yang sering dialami oleh pasien geriatri adalah Instability, Immobility, Infection, Incontinence, Intellectual impairment (Mild/Vascular Cognitive Impairment, Dementia), Impairment of hearing & vision, Impaction (konstipasi), Isolation (depresi), Inanition (malnutrisi), Impecunity (kemiskinan), Iatrogenic, Insomnia, Immune deficiency, dan Impotence. Berbagai syndrome geriatri ini saling berinteraksi secara kompleks. Oleh karena itu perlu pendekatan khusus dalam penilaian dan penatalaksanaan kasus geriatri,. Pendekatan ini sering dikenal sebagai Comprehensive Geriatric Assessment (CGA).
Kejadian Delirium pada Pasien Penderita Covid-19 dan Kemungkinan Perburukannya menjadi Gejala Demensia Gea Pandhita S; Abdul Gofir
Sanus Medical Journal Vol. 2 No. 2 (2021): Vol. 2 No. 2 (2021): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v2i2.7452

Abstract

Delirium merupakan suatu sindrom neurobehavioral (perubahan perilaku terkait gangguan neurologis) yang disebabkan oleh gangguan sementara aktivitas neuron (sel saraf otak) sebagai akibat sekunder dari gangguan sistemik. Prevalensi delirium pada pasien yang dirawat inap di rumah sakit cukup tinggi. Kejadian delirium lebih tinggi pada pasien dengan kasus kritis dan pada pasien penderita Covid-19. Kejadian delirium pada pasien dengan kasus kritis yang dirawat di rumah sakit adalah sekitar 31,8%. Angka kejadian ini meningkat menjadi sekitar 55% pada penderita Covid-19. Beberapa penelitian menunjukkan bahwa terdapat mekanisme patofisiologi delirium pada pasien penderita Covid-19 yang serupa dengan kejadian delirium pada pasien non-Covid-19. Bukti epidemiologi menunjukkan keterkaitan kejadian delirium pada pasien non-Covid-19 dengan kejadian demensia beberapa periode waktu setelahnya (Probabilitas sekitar 30%). Bukti radiologis dan patologi anatomi juga menunjukkan adanya proses patologis di otak akibat Covid-19 yang dapat mengakibatkan gangguan saraf otak ireversibel dan berkontribusi pada penurunan kognitif jangka panjang. Hal-hal tersebut menunjukkan kemungkinan besar dapat terjadi keterkaitan antara kejadian delirium yang dialami pasien penderita Covid-19 dengan kejadian demensia di masa mendatang.
Strategi Pemasaran pada Sistem Layanan Kesehatan Sidhi Laksono Purwowiyoto; Cattleya Ananda Vilda; Dionisius Indri Priyobodo; Ivana Raisa Cicilia
Sanus Medical Journal Vol. 4 No. 2 (2022): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v4i2.8062

Abstract

Health marketing is interdisciplinary because it uses certain concepts, methods, and techniques for classical and social marketing. The specialty of health marketing is that there are services and markets but no money equivalent.  Healthcare marketing differs mainly by the nature of the demand for health services. The beneficiary may not be the target of a marketing campaign, and the physician decides what, where, when, and how much to provide for a particular service. To understand the impact of marketing strategies on healthcare quality, it is essential to understand today's medical consumers who prefer to seek medical information online. They also have many health services, healthcare providers, and reviews from patients who contact providers.
A Rare Case of Metaplastic Breast Carcinoma with Squamous Differentiation in Young Female: A Case Report Rohana Agustina
Sanus Medical Journal Vol. 3 No. 1 (2022): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v3i1.8090

Abstract

Background. Metaplastic breast carcinoma is a very rare breast cancer, only about 0.2"‘1% of all invasive breast carcinomas. The prognosis of these cancer is poor and aggressive, reported to have lower response rates to conventional adjuvant chemotherapy and a worse clinical outcome after chemotherapy than other forms triple"‘negative breast carcinomas. Histopathologically, metaplastic breast carcinoma has distinct patterns with different outcomes. Among the types of metaplastic carcinoma, squamous cell, high grade spindle cell and high grade adenosquamous carcinoma are associated with the worst prognosis. We report one case of metaplastic breast carcinoma with squamous differentiation in young patient. Methods. We examined the breast tumor tissue of a female patient, evaluated the macroscopic and microscopic features and asked the patient about the clinical course of the disease. Inform consent was obtained from the patient for publication of this case report and accompanying images. Results. We reported a young female patient with final diagnosis of pathology Mixed Infiltrating Duct Carcinoma of No Special Type Grade 3 and Metaplastic Breast Carcinoma with Squamous Differentiation (30%) that has invaded fat tissue with Ductal Carcinoma Insitu of High Nuclear Grade 3 with basis of the operation is still positive for the tumor mass. Patients lost follow"‘up and did not continue therapy. Conclusion. Morphology of metaplastic breast carcinoma are important factors influencing patient outcome. Early diagnosis and wide local excision of the squamous"‘type metaplastic breast carcinoma mass can make a better prognosis.
Laporan Kasus Karsinoma Sel Skuamosa yang Berkembang dari Papiloma Tipe Inverted Sinonasal pada Pekerja Pabrik Cermin Fety Riani; Ita Marlita Sari
Sanus Medical Journal Vol. 3 No. 1 (2022): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v3i1.8103

Abstract

Background. Sinonasal inverted (PI) papilloma is a benign tumor of the mucosal epithelium of the nasal cavity and paranasal sinuses with an endophytic growth pattern. PI is more common in men in the fifth and sixth decades of life. These tumors have local aggressive behavior, high recurrence rates, and can undergo malignant transformation. Squamous cell carcinoma (SCC) is the most common malignancy developed from sinonasal PI. SSC developed from PI (KSS/PI) is related to exposure in the work environment. Methods. We report a sinonasal SCC/PI case by describing the clinical manifestations, radiological features, and histopathological features of a young male patient who was a non"‘smoker mirror"‘making factory worker. Results. Clinical manifestations of pain, epistaxis, and proptosis in patients suggest malignancy. Computed Tomography (CT) results showed lesions of the nasal cavity and paranasal sinuses with bone destruction and expansion of the mass to the intracranial point of the aggressive behavior of the tumor. Microscopic histopathological examination revealed endophytic squamous epithelial growth characteristic of an inverted papilloma accompanied by cell atypia, invasive components, connective tissue desmoplasia, and keratin pearls, suggesting a well"‘differentiated keratinized squamous cell carcinoma that developed from the sinonasal inverted papilloma. Exposure to dust in the work environment is related to malignancy in this patient. Conclusion. Support of clinical and radiological data, adequate sampling, and identification of malignancy morphology routinely on histopathological examination is critical to avoid misdiagnosis of sinonasal SCC/PI. A complete history directed at extracting risk factors can add value in establishing a diagnosis.
Karakteristik Mutasi EGFR pada Pasien Kanker Paru Jenis Adenokarsinoma yang Diterapi dengan Tyrosien Kinase Inhibitor (TKI) di Rumah Sakit Paru Dr. H.A Rotinsulu Bandung Desi Puspita; Vitri Dwi Astuti; Rina; Edi Sampurno
Sanus Medical Journal Vol. 3 No. 1 (2022): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v3i1.8431

Abstract

This descriptive study describes the proportion of Epidermal Growth Factor Receptor (EGFR) mutations in lung cancer Adenocarcinoma patients at Rumah Sakit Paru (RS Paru) Dr. H. A Rotinsulu Bandung in the range of 2018 to 2020. EGFR mutations were examined using RGQ thera screen technology Real"‘Time Polymerase Chain Reaction from FFPE or cytology smear. There are 44 data point mutations after examining the EGFR mutation. 59% cases were 40"‘60 years old group dan 52 % were female. It was found that in this group 86% patient with single mutation and 16% had doube mutations. EGFR mutations occurred in Exon 21 L858R in 13 cases (30 %), Exon 21 L861Q in 1 case (2%), Exon 19del in 24 cases (55%), double mutation Exon 19 and Exon 20 T790M type in 2 cases (4%), double mutation Exon 19del and Exon 21 in 4 cases (9%).

Page 2 of 9 | Total Record : 89

 1   2   3   4   5 

Filter by Year

2020 2025


Reset
Filter By Issues
All Issue Vol. 7 No. 1 (2025) Vol. 6 No. 2 (2024) Vol. 6 No. 1 (2024) Vol. 5 No. 2 (2023): Sanus Medical Journal Vol. 5 No. 2 (2023) Vol. 5 No. 1 (2023): Sanus Medical Journal Vol. 5 No. 1 (2023) Vol. 4 No. 2 (2022) Vol. 4 No. 2 (2022): Sanus Medical Journal Vol. 4 No. 1 (2022) Vol. 3 No. 1 (2022): Sanus Medical Journal Vol. 2 No. 2 (2021): Vol. 2 No. 2 (2021): Sanus Medical Journal Vol. 2 No. 1 (2021): Vol. 2 No. 1 (2021): Sanus Medical Journal Vol. 2 No. 2 (2021) Vol. 2 No. 1 (2021) Vol. 1 No. 1 (2020): Sanus Medical Journal Vol. 1 No. 1 (2020) More Issue