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Sanus Medical Journal
Published by Universitas Muhammadiyah Prof. Dr. Hamka
ISSN : -     EISSN : 2745868     DOI : https://doi.org/10.22236/sanus
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Sanus Medical Journal is a peer-reviewed medical and health journal published periodically every six months. Sanus Medical Journal publishes descriptive, analytical, and experimental studies, reviews, systematic reviews, case reports, letters, and editorials in the fields of Medicine, Health, Medical and Health Education, and Islamic Medicine. The scope of Sanus Medical Journal goes beyond the boundaries of discussions in the fields of clinical medicine and health in general, by providing new insights into etiologies, determinants, distribution, management and prevention of diseases in individuals and communities. Sanus Medical Journal attempts to meet the demands of rapid developments in information and medical and health research by committing to reduce the range of online publications to around six weeks after the submission of a manuscript. Articles will be published online in advance, and the printed version included in the next scheduled edition. Sanus Medical Journal will continue to strive to improve its scientific reputation by publishing quality articles reviewed by experts who are highly competent in their respective fields. Sanus Medical Journal greatly appreciates the contributions of authors from related disciplines. Manuscripts can be sent via email to: smjournal@uhamka.ac.id or via the website https://journal.uhamka.ac.id/index.php/smj.
Arjuna Subject : Kedokteran - Farmakologi (Medis)
Articles 89 Documents
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Hubungan Aktivitas Fisik Sedenter dengan Siklus Menstruasi Mahasiswi Fakultas Kedokteran UHAMKA Anisa Nabila Hanifah Hanifah; Wawang Setiawan Sukarya
Sanus Medical Journal Vol. 5 No. 2 (2023): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v5i2.14487

Abstract

High intensity physical activity affects Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) while low physical activity that leads to less body movement affects oxidative energy reserves. This study aims to determine the relationship between sedentary physical activity and the menstrual cycle of students of the Faculty of Medicine, Universitas Muhammadiyah Prof. Dr. HAMKA (UHAMKA). The research design was an observational analytic survey with a cross sectional approach. The sample size was determined by the Slovin formula, which was 92 subjects. The results showed that most of the female students (95.65%) with sedentary physical activity, and female students with abnormal menstrual cycle disorders (polymenorrhea) were 31.52% oligomenorrhea 11.96%, hypomenorrhea 64.13%, while hypermenorrhea was only 3.27%. There is no significant relationship between the level of sedentary physical activity with menstrual cycle disorders.
Examining Oxygen Saturation and Peak Volume Correlation in Respiratory Disorders: A Study at PCM/PCA Ciledug Rizni Fitriana; Irena Ujianti; Teguh Haryo Sasongko; Takashi Yashiro
Sanus Medical Journal Vol. 5 No. 2 (2023): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v5i2.14488

Abstract

This cross-sectional study sought to determine the correlation between oxygen saturation and peak flow meter readings, taking into account hemoglobin levels. Participants aged 55 years and over were examined using direct measurement methods, with hemoglobin measured via the strip test method, and oxygen saturation and peak flow meter values assessed using a pulse oximeter and peak flow meter, respectively. Analysis of the collected data from 12 subjects, averaged 63 years old, revealed a significant correlation between oxygen saturation (average 96.6%) and peak flow volume (average 223.3 mL/mnt) (r=0.727, p=0.007). The findings suggest that this relationship is more potent in individuals with respiratory disorders or under certain environmental risk factors. Nonetheless, in healthier contexts, the correlation may be weaker or absent, emphasizing the need for further research to enhance the management of respiratory and lung disorders
Hubungan Antara Faktor Risiko Hendaya Kognitif Ringan Pada Pasien Lanjut Usia Di Jakarta Timur Erlina Erlina Pudyastuti; Zamrina Adilafatma
Sanus Medical Journal Vol. 5 No. 2 (2023): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v5i2.14489

Abstract

The research objectives in detail are to determine the risk factors for mild cognitive impairment in the elderly and understanding the factors that affect the majority of mild cognitive impairment in the elderly. This research is an observational case-control study and the research method used is multi-variant data analysis and epidemiological information. The results between methods describe the effect of hypertension and physical activity have big influence on mild cognitive. Conclusion The factors that most influence mild cognitive impairment are hypertension and physical activity
Hubungan Ibu Pekerja dengan Perkembangan Anak Balita Usia 3-59 Bulan di Wilayah Kerja Posyandu 1 Banyu Biru Mauk dengan Menggunakan Kuesioner Praskrining Perkembangan (KPSP) Dewi Novita Sari; Salsabil Salsabil Nadiyyah; Leli Hesti Indriyati
Sanus Medical Journal Vol. 5 No. 2 (2023): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v5i2.14491

Abstract

Penelitian ini melihat hubungan antara ibu pekerja dengan perkembangan balita usia 3-59 bulan dengan menggunakan Kuesioner Praskrining Perkembangan (KPSP) yang dilakukan pada bulan Januari 2022 sampai April 2022 di Posyandu 1 Banyu Biru Mauk. Penelitian ini dilakukan menggunakan desain analitik observasional dengan pendekatan cross sectional. Responden pada penelitian ini sebanyak 48 orang ibu yang terdiri atas ibu rumah tangga dan ibu pekerja. Hasil penelitian didapatkan sebanyak tiga dari 48 balita (6%), mengalami perkembangan terlambat. Berdasarkan hasil penelitian tidak didapatkan hubungan antara ibu pekerja dengan keterlambatan perkembangan pada anak balita (p=1,000). Dari penelitian ini disarankan penelitian selanjutnya dengan jumlah sampel yang lebih banyak dan menambahkan beberapa faktor yang mempengaruhi perkembangan
Hubungan Faktor Risiko Eksternal terhadap Kejadian Otitis Media Akut pada Balita di RS Aminah Ciledug Nanda Nanda Emira Putri; Roito Elmina Gogo Harahap; Ismaili Fasha; Lailana Purvis
Sanus Medical Journal Vol. 5 No. 2 (2023): Sanus Medical Journal
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v5i2.14493

Abstract

This study examined the correlation of external risk factors to the incidence of AOM in toddlers and preschoolers. This research used an observational analytic design with a cross-sectional approach and data processing uses univariate, bivariate and multivariate analysis. Of the 61 research subjects, the majority of toddlers with AOM were 1-3 years old, 32 children (52.5%), 33 children (54.1%) were female, 37 children (60.7%) had perforation stage. 52 children (85.2%) received exclusive breastfeeding. The results showed that the four variables, including breastfeeding duration, use of pacifiers, PCV vaccinations, and history of ARI (Acute Respiratory Infection), correlated to incidences of acute otitis media. PCV vaccination and history of ARI are the most influencing variables with p-values of 0.024 and 0.006. There is a relationship between external risk factors and the incidence of AOM in toddlers, where the most influential variables are the administration of the PCV vaccine and a history of upper respiratory infection. The researcher of this study suggests at least three doses of PCV vaccination for children at the ages 2, 4, and 6 months, alongside the protection from triggers of ARI to prevent the occurrence of AOM.
Ikan Zebra (Danio rerio) sebagai Binatang Model pada Penelitian Biomedis dan Cara Pemeliharaannya Khotimah, Husnul; M. Muljohadi Al
Sanus Medical Journal Vol. 1 No. 1 (2020)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v1i1.5301

Abstract

Biomedical research requires suitable model organisms to be able to understand the pathogenesis of disease at the cellular and molecular level and the suitability of systems for the development and testing of new therapies. The choice of model organisms for biomedical research depends very much on the research objectives. Basically, the selection of model organisms is based on several aspects, namely: biological, technical and historical aspects. The general criteria for selecting model organisms are: small size, fast reproduction time, low and easy maintenance, easy experimental techniques, complete basic information. The development of research using animal models further leads to the level of genetic functional conservation in the basic processes of cell biology between mammals and invertebrates such as fruit flies (Drosophila melanogaster) and nematode worms (Caenorhabditis elegans). However, there are significant limitations between mammals and invertebrates, among others due to differences in organ systems and their development, so now widely used zebra fish (Danio rerio) as model organisms that bridge between invertebrates and vertebrates. In addition to these reasons there are several other scientific reasons that make zebra fish a superior organism model for biomedical research, namely: having a high homology with humans (75%), transparent embryos, high levels of fecundity, fast embryogenesis, relatively fast life span , procurement and maintenance is relatively inexpensive, complete basic information and genetic information (whole genome sequencing), has a cardiovascular system, nerves, immune system and digestive system similar to mammals, sensitive to environmental changes so that many bio-indicators are used for toxicity testing and testing and development drug.
Comparing Clock Test for Cognitive Screening: Quantitative Analysis of Five Scoring Methods – What Is Optimal? Gea Pandhita; Bambang Sutrisna; Samekto Wibowo
Sanus Medical Journal Vol. 1 No. 1 (2020)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v1i1.5302

Abstract

Objectives: The clock drawing test (CDT) is a widely used cognitive screening tool that has been well accepted. However, it is still questionable which scoring system is the best. We assessed the correlation of five common scoring methods of the CDT with Mini Mental State Examination (MMSE), and intercorrelations between each different scoring system. Methods: CDT scores of different scoring systems from participants from the geriatric club in Pondok Kopi Jakarta Islamic Hospital, were compared. The CDT was scored according to the methods of Rouleau, Babins, Mendez, Lin, and Shulman. Correlation coefficients between the five scoring methods of the CDT with MMSE were calculated, as well as the intercorrelations between each different scoring system. Results: The study sample consisted of 106 non-demented subjects, aged between 60 and 77 years. The five scoring methods of the CDT correlated significantly with MMSE, but correlation coefficients were moderate (r = 0.43 to r = 0.46). The highest was Lin's method (r = 0.46). Especially, correlation coefficients between the five scoring methods of the CDT with MMSE attention domain were higher (r = 0.42 to r = 0.52). The intercorrelations between each different scoring system were high (r = 0.87 to r = 0.99). The correlation coefficients between Rouleau's method with Mendez's method was the highest (r = 0.99). Conclusions: The correlation of five common scoring methods of the CDT with MMSE were moderate positive. The CDT scored according to the method of Lin was the highest. The intercorrelations between each different scoring system were high.
Deep Vein Thrombosis: How do I Manage in Daily Practice Sidhi Laksono
Sanus Medical Journal Vol. 1 No. 1 (2020)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v1i1.5352

Abstract

Deep vein thrombosis (DVT) is part of venous thromboembolism disease dan the incidence increases sharply with age. In European countries, DVT incidence is 70-140 cases/100,000 person-year. Patient with DVT, short-term mortality rates were 2-5% and more frequent in proximal than distal DVT. DVT is a common condition for complication such as post phlebitic syndrome, pulmonary embolism and death. An algorithm strategy combining pre-test probability, D-dimer testing and compressible Doppler ultrasound imaging can be applied for suspected lower extremity DVT. Patients with low pre-test probability and a negative D-dimer test result can be excluded from diagnosis of DVT without the need for Doppler ultrasound imaging. Primary treatment of DVT is anticoagulation therapy, intervention using thrombolysis and vena cava filters are for special conditions. The duration of anticoagulation therapy depends on the risk factors.
Peran Sel Punca dalam Pengobatan Regeneratif Silmi Mariya
Sanus Medical Journal Vol. 1 No. 1 (2020)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v1i1.5353

Abstract

Penggunaan sel punca merupakan hal yang sangat menguntungkan bagi ilmu pengetahuan, bagaimana organisme dapat berkembang dari satu sel dan bagaimana sel yang sehat dapat mengganti kerusakan sel pada mahluk hidup. Hal yang menjanjikan ini membuat para peneliti mengembangkan lebih jauh kemungkinan pengobatan menggunakan sel punca, untuk suatu penyakit yang dikenal dengan pengobatan regeneratif. Sel punca mempunyai dua karakteristik penting, yang membedakan mereka dari jenis sel lainnya.
Stem Cell Therapy for Ischemic Heart Disease: Clinical Use PURWOWIYOTO, Sidhi Laksono
Sanus Medical Journal Vol. 1 No. 1 (2020)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v1i1.5402

Abstract

Ischemic heart disease is still becoming a cause of morbidity and mortality in the world. Regenerative cellular or stem cell therapy is a new and emerging as an alternative option for this disease. There are several stem cell types that used in ischemic heart disease, most used stem cell for this treatment are bone marrow-derived stem cell and mesenchymal stem cell. The mechanism of action for stem cell therapy is depends on transdifferentiation and paracrine effect. It effects the release of cytokines, chemokines and growth factors that inhibits apoptosis and fibrosis, enhance contractility and activate regenerative mechanism. Factors associated with the efficacy of stem cell therapy are delivery route to target myocardium, number of stem cell infusion, injection timing, physical condition of patient and stem cell microenvironment.

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