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FAKULTAS FARMASI UNIVERSETAS JENDERAL ACHMAD YANI Jl. Terusan Jenderal Sudirman PO BOX 148, Cimahi, Jawa Barat, 40531, Indonesia
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Kartika : Jurnal Ilmiah Farmasi
Published by Universitas Jenderal Achmad Yani
ISSN : 23546565     EISSN : 25023438     DOI : https://doi.org/10.26874/kjif.v6i1.135
Core Subject : Health, Science, Social,
Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Social Sciences
Kartika: Jurnal Ilmiah Farmasi (KJIF) merupakan media publikasi ilmiah dalam bidang kefarmasian yang diterbitkan oleh Fakultas Farmasi Universitas Jenderal Achmad Yani, bekerjasama dengan Ikatan Apoteker Indonesia (PD IAI Jawa Barat). Ruang lingkup artikel yang diterbitkan adalah: Farmasetika, Kimia Farmasi, Kimia Analisa, Farmasi Fisika, Farmakognosi dan Etnobotani, Natural Produk, Farmakologi dan Toksikologi, Praktik Kefarmasian dan Farmasi Rumah Sakit, Farmakogenomik, Farmakoekonomi, Studi Kasus dan Uji Klinis.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 125 Documents
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FICI VALUE OF AQUILARIA MALACCENSIS LEAVES EXTRACT AND AMOXICILLIN AGAINST PROTEUS MIRABILIS AND PSEUDOMONAS AERUGINOSA nobelia elok valentine; Pratiwi Apridamayanti; Rafika Sari
Kartika : Jurnal Ilmiah Farmasi Vol 6 No 2 (2018)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v6i2.157

Abstract

Abstract Infection is a common disease caused by microbes. The use of antimicrobial drugs such as Amoxicillin is most widely used in Indonesia, but has develop resistance. The resistance of Amoxicillin can be overcome by combining it with Karas leaves (Aquilaria malaccensis Lam.) which has an antibacterial activity. This research was conducted to know the value of Fractional Inhibitory Concentration Index (FICI) from the combination of ethanolic Karas leaves extract (A.malaccensis Lam.) with amoxicillin in Gram-negative bacteria test, that is, Proteus mirabilis and Pseudomonas aeruginosa. This research was used disc diffusion method by Kirby Bauer. Minimum Inhibitory Concentration (MIC) result of ethanolic karas leaves extract (A.malaccensis Lam.)  in P.mirabilis and P.aeruginosa was 0.5mg/ml. MIC’s result of amoxicillin in P. mirabilis and P.aeruginosa sequentially were 0.0039 and 0.0625 mg/ml. Then, evaluation of MIC value from combination of ethanolic karas leaves extract and amoxicillin (1/4 x MIC, 1/2 x MIC, 1 x MIC, 2 x MIC and 4 x MIC) showed that the combination of ethanolic karas leaves extract with amoxicillin has characteristics of FICI value on each bacteria, P. aeruginosa: 0.5 (synergistic) and P.mirabilis: 8 (antagonist) Keyword: antibacteria, Aquilaria malaccensis, amoxicillin, FICI
Minimum Inhibitory Concentration Determination of Bambusa vulgaris Leaves Extract Against Skin and Digestive Diseases Bacteria Kelly Zhiang; Rafika Sari; Pratiwi Apridamayanti
Kartika : Jurnal Ilmiah Farmasi Vol 7 No 1 (2019)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v7i1.158

Abstract

Infections that are commonly happened in developing countries such as Indonesia are skin infection that caused by Staphylococcus aureus and Staphylococcus epidermidis, and digestive infection that caused by Bacillus subtilis and Bacillus cereus. The ethanol extract of Bambusa vulgaris leaves contained metabolite compounds that potential to have antibacterial activity. This study aimed to determine MIC (Minimum Inhibitory Concentration) value of ethanol extract of Bambusa vulgaris leaves against those four bacteria. The research was conducted by Kirby-Bauer disc diffusion method using ethanol extract of Bambusa vulgaris leaves with concentration variations of 80 mg/mL, 40 mg/mL, 20 mg/mL, 10 mg/mL, 5 mg/mL, 2.5 mg/mL, and 1.25 mg/mL. The results showed that ethanol extract of Bambusa vulgaris leaves can inhibit the growth of all four bacteria with MIC value against Staphylococcus aureus and Bacillus subtilis is 20 mg/mL, with inhibition zone diameter of 7,33 ± 0,416 mm and 6,32 ± 0,057 mm respectively. While the MIC value against Staphylococcus epidermidis and Bacillus cereus is 10 mg/mL, with inhibitory zone diameter obtained respectively 7,33 ± 0,416 mm and 6,07 ± 0,029 mm. The conclusion of this research was that ethanol extract of Bambusa vulgaris leaves had inhibition zone with MIC value 20 mg/mL against Staphylococcus aureus and Bacillus subtilis, and 10 mg/mL against Staphylococcus epidermidis and Bacillus cereus.Keywords: Ethanol extract of Bambusa vulgaris leaves, antibacterial, disc diffusion, MIC (Minimum Inhibitory Concentration)
Pemanfaatan Lendir Bekicot Afrika (Achatina fulica) sebagai Obat Luka Bakar Berbasis Nanoemulsi Hanidya Fidela Ulayya; Yuniar Ayu Limantini Suwele; Erika Indah Junior; Nisia Anindita Rinjani; Syarifat izat; Suprapto Suprapto
Kartika : Jurnal Ilmiah Farmasi Vol 6 No 2 (2018)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v6i2.159

Abstract

Abstrak Indonesia merupakan negara tropis yang ditemukan banyak spesies bekicot, salah satunya adalah Achatina fulica (siput tanah). Keberadaan A. fulica kurang dimanfaatkan dan lendirnya dapat dimanfaatkan untuk  mempercepat pengeringan dan penutupan luka. Penelitian sebelumnya menunjukkan bahwa lendir bekicot mengandung acharan sulfat yaitu glycosaminoglycan yang pada fase proliferasi akan membentuk komplek yang berperan penting pada penyembuhan luka. Penelitian ini dilakukan untuk mengetahui cara mengolah mucus Achatina fulica menjadi sediaan nanoemulsi sebagai obat luka bakar dan menguji efek menyembuhkan luka bakar. Sediaan nanoemulsi dari mucus A. fulica adalah sistem w/o (air dalam minyak) dengan fase air adalah gliserol, fase minyak adalah kitosan, dan emulgator adalah Tween 80 dan Span 80. Hasil evaluasi sediaan nanopartikel yang mengandung lender A. fulica menunjukkan distribusi partikel yang baik dan nilai Dispersion Medium Viscosity (Distribusi partikel) didapati hasil sebesar 0,9 mPa.s. Hal ini menunjukkan sediaan nanoemulsi yang diperoleh menunjukkan stabilitas yang baik. Kata kunci:   nanoemulsi, Achatina fulica, luka bakar Utilitazion of  African snail mucus (Achatina fulica) as nanoemulsion for wound burn  Abstract Indonesia is a tropical country that is found in many snail species, one of which is Achatina fulica (land snail). The existence of A. fulica is underutilized and the mucus can be used to speed up drying and wound closure. Previous research shows that snail mucus contains acharan sulfate, namely glycosaminoglycan, which in the proliferation phase will form a complex that plays an important role in wound healing. This study was conducted to find out how to process Achatina fulica mucus into nanoemulsion as a burn medicine and test the effect of curing burns. Nanoemulsion from mucus A. fulica is a system of w/o (water in oil) with water phase is glycerol, oil phase is chitosan, and emulgator is Tween 80 and Span 80. The evaluation of nanoparticles containing lender A. fulica shows particle distribution which is good and the value of Medium Viscosity Dispersion (Particle distribution) is found to be 0.9 mPa.s. This shows that the nanoemulsion obtained showed good stability. Keywords: nanoemulsion, Achatina fulica, burns
Kajian penggunaan obat misoprostol sebagai off-label pada pelaksanaan persalinan di Klinik Utama Al-Islam Bandung Ani Anggriani; Ida Lisni; Wildan Muttaqien
Kartika : Jurnal Ilmiah Farmasi Vol 7 No 2 (2019)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v7i2.161

Abstract

Abstrak Misoprostol sebagai off-label sering digunakan dalam tindakan persalinan baik untuk induksi persalinan maupun untuk pencegahan perdarahan pasca persalinan. Perdarahan pasca persalinan merupakan peyebab terbanyak pada kasus kematian akibat persalinan. Penelitian ini bertujuan untuk mengidentifikasi ketepatan penggunaan obat misoprostol sebagai off-label berdasarkan kriteria penggunaan medis dan ketepatan dosis yang diberikan kepada pasien. Penelitian ini merupakan penelitian observasional data rekam medis pasien yang dilakukan secara retrospektif di Klinik Utama Al-Islam Bandung. Penelitian dilakukan terhadap 87 data rekam medik pasien selama periode bulan Januari-Desember 2016. Hasil menunjukkan bahwa 100% penggunaan misoprostol sebagai off-label sesuai dengan kriteria penggunaan medis dan tepat dosis. Terdapat 64% dari total pasien yang diberikan misoprostol dengan total dosis sebesar 800 μg. Kata kunci: Misoprostol, Off-Label, Persalinan  Abstract As off-label misoprostol is the most used in labor either for labor induction or for prevention of postpartum hemorrhage. Postnatal bleeding is the most common cause of death due to childbirth. The purpose of this research is to identify the accuracy of misoprostol used as off-label based on the criteria of medication and the dose accuration for the patient. An observational retrospective research on medical record data of patients at Al-Islam Main Clinic Bandung. During 2016 had 87 patient's data from January to December was obtained. The results showed that 100% of misoprostol is used as off-label following the criteria of medication and dose accuration. Therefore 64% of total patients had given misoprostol for 800 μg each. Keywords: Labor, Misoprostol, Off-Label
Efek ekstrak daun sirih (Piper betle L.) pada pengobatan scabies hewan ternak kambing kacang (Capra hircus) Nur Sriani Rezki; Abdul Wahid Jamaluddin; Muhammad Fadhlullah Mursalim
Kartika : Jurnal Ilmiah Farmasi Vol 7 No 1 (2019)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v7i1.170

Abstract

Salah satu penyakit infeksi parasit yang sering dijumpai mengganggu ternak kambing adalah scabies disebabkan oleh Sarcoptes scabiei. Penelitian ini bertujuan untuk menguji efek ekstrak daun sirih (Piper betle L.) pada kambing kacang (Capra hircus) yang terinfeksi scabies. Hewan uji dikelompokkan menjadi 5 perlakuan, yaitu kontrol positif, kontrol negatif, ekstrak daun sirih  10, 20 dan 30%. Parameter yang diamati adalah adanya alopecia, penebalan dan keropeng pada permukaan luka. Hasil pengamatan menunjukkan ekstrak daun sirih 10, 20 dan 30% memberikan aktivitas yang baik terhadap penyembuhan scabies pada kambing kacang, dimana efek terbaik diberikan oleh ekstrak daun sirih 30%. Kata Kunci:  ekstrak daun sirih, kambing Kacang, scabies Effects of betel leaf extract (Piper betle L.) on the treatment of scabies for sheep goats (Capra hircus) Abstract One of the parasitic infectious diseases that are often found to interfere with goat livestock is scabies caused by Sarcoptes scabiei. This study aimed to examine the effect of betel leaf extract (Piper betle L.) on scabies-infected goat (Capra hircus) goats. Test animals were grouped into 5 treatments, namely positive control, negative control, betel leaf extract 10, 20 and 30%. The parameters observed were the presence of alopecia, thickening and scab on the wound surface. Observation results showed that betel leaf extracts of 10, 20 and 30% gave a good activity to cure scabies in goat nuts, where the best effect was given by 30% betel leaf extract. Keywords: extract betel leaf, Indonesian native Kacang goat, scabies
SURVEY TENTANG KEMAMPUAN BEKERJA SAMA APOTEKER DI BALI Desak Ketut Ernawati; Ketut Agus Adrianta
Kartika : Jurnal Ilmiah Farmasi Vol 7 No 1 (2019)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v7i1.171

Abstract

Abstrak Tenaga kesehatan diharapkan mampu bekerja sama dengan profesi lain pada pelayanan kesehatan sehingga kurangnya kemampuan bekerja sama dapat menghambat pelayanan kesehatan yang efektif. Penelitian ini dilakukan untuk mengetahui pemahaman apoteker dalam bekerja sama dengan profesi lain. Penelitian merupakan penelitian potong selintang dengan menggunakan survey kolaborasi yang terdiri dari 13 pernyataan tentang pemahaman kemampuan bekerja sama yang diberikan skala dari tidak ada sampai sangat baik (1-5). Faktor yang diteliti adalah pengetahuan dan ketrampilan bekerja sama. Survey menggali hal-hal yang dibutuhkan oleh apoteker dalam bekerja sama dengan profesi kesehatan lain dan hambatan apoteker dalam bekerja sama dengan profesi lain. Survey diberikan kepada seluruh apoteker yang menghadiri Konferensi Daerah di Bali pada pertengahan Tahun 2018. Data dianalisa dengan menggunakan SPSS versi 22. Total responden yang mengikuti survey adalah 274, 52,8% responden bekerja di apotek, 24,7% bekerja di dan 5% bekerja di klinik. Analisis Anova menunjukkan terdapat perbedaan bermakna dalam pengetahuan (p=0,001) dan ketrampilan dalam bekerja sama (p=0,03) berdasarkan tempat bekerja. Hasil kualitatif diperoleh hasil bahwa hal yang dianggap penting oleh apoteker dalam berkolaborasi antara lain kemampuan berkomunikasi, adanya wadah untuk berkomunikasi serta pemahaman tentang peranan tugas dan tanggungjawab profesi lain sehingga kurangnya hal l tersebut merupakan faktor penghambat kemampuan bekerja sama dengan profesi lain. Disarankan dimasa depan diperlukan kegiatan yang dapat meningkatkan kemampuan bekerja sama antar profesi kesehatan.   Kata kunci: Apoteker, ketrampilan, pengetahuan bekerja sama A survey of collaborative competencies amongst pharmacist in Bali  Abstract Healthcare professional are expected to be able to work together with other professions in the health service. So that the lack of ability to work together can hamper effective health services. This research was conducted to determine the understanding of pharmacists in collaboration with other professions. The research is a cross-sectional study using a collaborative survey consisting of 13 statements about understanding the ability to work together given a scale from none to very good (1-5). The factors studied are the knowledge and skills to work together. The survey explores the things needed by pharmacists in working with other health professions and the obstacles of pharmacists in working with other professions. The survey was given to all pharmacists who attended the Regional Conference in Bali in mid-2018. Data were analysed using SPSS version 22. Total respondents who took the survey were 274, 52.8% of respondents worked in pharmacies, 24.7% worked in and 5% work in the clinic. Anova analysis showed that there were significant differences in knowledge (p = 0.001) and skills in working together (p = 0.03) based on the place of work. Qualitative results obtained result that what is considered important by pharmacists in collaboration include the ability to communicate, the existence of a place to communicate and an understanding of the role of duties and responsibilities of other professions so that this lack of l is an obstacle to the ability to cooperate with other professions. It is suggested that in the future activities are needed that can improve the ability to work together between healthcare professional. Keywords: Knowledge in collaboration; skills in collaboration; pharmacist
UJI AKTIVITAS ANTIOKSIDAN DAN ANTIKANKER EKSTRAK BATANG MURBEI (MORUS ALBA L.) TERHADAP SEL KANKER WIDR SECARA IN VITRO Asril Burhan; Andi Nur Aisyah; Akbar Awaluddin; Zulham Zulham; Burhanuddin Taebe; Abdul Gafur
Kartika : Jurnal Ilmiah Farmasi Vol 7 No 1 (2019)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v7i1.173

Abstract

Abstrak Murbei merupakan salah satu obat yang penting didalam pengobatan tradisional Cina. Murbei mengandung berbagai macam senyawa diantaranya fenol dan flavanoid yang umunya berfungsi sebagai antioksidan alami dan juga memiliki fungsi antikanker. Penelitian ini bertujuan untuk mengetahui kadar fenolik, aktivitas antioksidan dan antikanker ekstrak batang murbei (Morus alba L.). Pembuatan ekstrak dilakukan dengan cara maserasi menggunakan pelarut etanol. Penetapan kadar fenolik menggunakan reagen Folin-Ciocalteu, pengujian aktivitas antioksidan menggunakan metode ABTS dan pengujian aktivitas antikanker menggunakan metode MTT terhadap sel kanker WIDR dan sel vero. Hasil pengujian menunjukkan kadar total fenolik ekstrak batang murbei sebesar 35,9%. Nilai aktivitas antioksidan ekstrak batang murbei adalah  83,18 µg/mL. Aktivitas antikanker pada sel WIDR menunjukkan nilai IC50 71,24 µg/ml dan pada sel vero memiliki nilai IC50 154,241 µg/ml. Dapat disimpulkan bahwa ekstrak etanol batang murbei (Morus alba L.) memilki aktivitas antioksidan yang kuat dan berpotensi sebagai antikanker alami yang bekerja selektif terhadap sel kanker. Kata kunci : Murbei (Morus alba L.), batang, IC50, antioksidan, antikanker Antioxydant and anticancer effect of murberry (Morus alba L.) stem extract in vitro Abstract Mulberry is one of the important medicines in traditional Chinese medicine. Mulberry contains a variety of compounds including phenols and flavonoids which generally function as natural antioxidants and also have anticancer functions. This study aims to determine phenolic levels, antioxidant activity and anticancer of mulberry stem extract (Morus alba L.). Extracts were made by maceration using ethanol as a solvent. Determination of phenolic levels using the Folin-Ciocalteu reagent, testing of antioxidant activity using the ABTS method and testing of anticancer activity using the MTT method against WIDR cancer cells and vero cells. The test results showed total phenolic levels of mulberry stem extract amounted to 35.9%. The antioxidant activity value of mulberry stem extract was 83.18 µg / mL. Anticancer activity in WIDR cells showed IC50 values 71.24 µg / ml and vero cells had IC50 values 154.224 µg / ml. It can be concluded that the ethanol extract of mulberry stem (Morus alba L.) has a strong antioxidant activity and has the potential as a natural anticancer that works selectively against cancer cells. Keywords: Mulberry (Morus alba L.), stem extract, IC50, antioxidant, anticancer
Aktivitas antihiperurisemia teh asam daun tin (Ficus carica) terhadap tikus putih (Rattus norvegicus) Sierra Aprilia Junaidah Az-Zahro; Siti Humaira Umami; Uswatun Hasanah; Ernanin Dyah Wijayanti
Kartika : Jurnal Ilmiah Farmasi Vol 7 No 1 (2019)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v7i1.176

Abstract

AbstrakTin (Ficus carica) merupakan tanaman yang memiliki aktivitas antioksidan sehingga dapat digunakan sebagai alternatif pengobatan penyakit degeneratif salah satunya yaitu hiperurisemia. Aktivitas antioksidan tersebut dapat ditingkatkan melalui proses fermentasi. Hasil dari proses fermentasi tersebut berupa teh asam. Tujuan penelitian ini adalah untuk mengetahui aktivitas antihiperurisemia teh asam daun tin pada tikus putih (Rattus norvegicus). Pengujian dilakukan terhadap 5 kelompok kontrol negatif (Pakan tinggi purin 10,8 ml/kgBB), kontrol positif (Allopurinol 9 ml/kgBB), teh asam daun tin dosis 20, 25 dan 30 ml/kgBB. Pemberian sediaan uji setiap hari selama 8 hari. Pengukuran kadar asam urat dengan menggunakan metode fotometrik enzimatis. Pengambilan sampel darah melalui vena jantung pada hari ke 22. Hasil pengukuran kadar asam urat dengan pemberian teh asam daun tin dengan dosis 30 ml/kgBB menunjukkan kadar asam urat paling rendah dibandingkan dengan kontrol positif. Dapat disimpulkan bahwa teh asam daun tin dengan dosis 30 mL/kgBB memiliki aktivitas antihiperurisemia terhadap hewan uji. Kata Kunci: antihiperurisemia, fermentasi kombucha, teh asam daun tin.Antihyperuricemic activity of fig (Ficus carica) sour tea on male rat (Rattus norvegicus) AbstractFig (Ficus carica) are known to have antioxidant activity, thus it can be used as an alternative treatment of degenerative diseases, such as hyperuricemia. The antioxidant activity of Fig can be increased by the fermentation process. The result of the fermentation process is sour tea. This study aimed to investigate the antihyperuricemic activity of Fig (Ficus carica) sour tea on male rat (Rattus norvegicus). This research was a True experiment study with the design of Post Test Control Group. Research samples were divided into 5 groups, in which there were 3 rat in each group. Group 1 was the positive control (Allopurinol 1,8 ml/200grBW), and Group II was the negative control (High purin diet 2,16 ml/grBW). In addition, the Group III, IV, and V were the experimental group with different dose of sour tea of Fig; 4ml/200grBW/day, 5ml/200grBW/day, and 6ml/200grBW/day for 8 days. Identification of uric acid levels was performed using enzymatic photometric method. Meanwhile, the serum samples were taken from the heart vein on the 22nd day of experiment. The results the best dose of sour tea of Fig in lowering the level of uric acid in male rat (Rattus norvegicus) was 6 ml/200grBW/day (3,87 mg/dl) compared to the positive controls which had the average level of 4,2 mg/dl. In addition, the result of One Way ANOVA demonstrated the significant difference in the probability value of 0,05. Therefore, it can be concluded that sour tea of Fig (Ficus carica) can effectively lower the uric acid level of male (Rattus norvegicus). Keywords: antihyperuricemic, kombucha fermentation, sour tea of Fig leaves.
Studi etnomedicine pengobatan luka terbuka dan sakit kulit pada beberapa etnis di Provinsi Kalimantan Timur Rohmat Mujahid; Slamet Wahyono; Wahyu Joko Priyambodo; Dyah Subositi
Kartika : Jurnal Ilmiah Farmasi Vol 7 No 1 (2019)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v7i1.178

Abstract

Abstrak Pemetaan penggunaan tumbuhan sebagai obat dan jamu di Kalimantan Timur telah dilakukan dalam bentuk riset tanaman obat dan jamu (RISTOJA) 2015. Eksplorasi dilakukan terhadap 5 etnis yaitu Bahau, Berau, Apokayan, Kutai dan Bentian. Data dikumpulkan dari 5 orang pengobat dan penyehat tradisional (hattra) pada masing-masing etnis yang dipilih secara purposive untuk memperoleh data terkait penggunaan tumbuhan dalam pengobatan. Sejumlah 520 ramuan dikelompokkan dalam 70 jenis keluhan/penyakit. Diperoleh 47 ramuan yang dapat digunakan untuk pengobatan luka terbuka dan sakit kulit, dengan 25 ramuan untuk pengobatan luka terbuka dan 22 ramuan utnuk pengobatan sakit kulit. Hasil identifikasi tumbuhan yang digunakan pada ramuan menunjukkan ada 27 tumbuhan yang digunakan pada ramuan luka terbuka dan 26 tumbuhan yang digunakan pada ramuan sakit kulit. Identifikasi tumbuhan menunjukkan adanya 39 jenis tumbuhan dimana 14 jenis diantaranya memiliki lebih dari 1.000 publikasi terkait penggunaan secara medis dan penggunaan sebagai anti bakteri dan hanya 7 jenis diantaranya yang memiliki publikasi kurang dari 100. Kata kunci : Riset Tanaman Obat dan Jamu, RISTOJA 2015, luka terbuka, sakit kulit, etnis Ethnomedicine studies on treatment of open wounds and skin aches in several ethnicities in the province of East Kalimantan Abstract Mapping the use of plants as medicine and herbal medicine in East Kalimantan has been carried out in the form of research on medicinal plants and herbs (RISTOJA) 2015. Exploration is carried out on 5 ethnic groups namely Bahau, Berau, Apokayan, Kutai and Bentian. Data were collected from 5 traditional healers (hattra) in each ethnic who were selected purposively to obtain data related to the use of plants in medicine. A total of 520 herbs are grouped into 70 types of complaints / diseases. Obtained 47 ingredients that can be used for the treatment of open wounds and skin ailments, with 25 herbs for the treatment of open wounds and 22 herbs for the treatment of skin ailments. The results of the identification of plants used in the concoction showed that there were 27 plants used in the open wound herb and 26 plants used in the skin ache mixture. Plant identification shows that there are 39 species of plants where 14 of them have more than 1,000 publications related to medical use and anti-bacterial use and only 7 of them have less than 100 publications. Keywords : Riset tumbuhan obat dan jamu, wounds, skin aches, ethnic
PENGGUNAAN OBAT KARDIOVASKULAR PADA PASIEN PENYAKIT JANTUNG KORONER DI RUANG RAWAT INAP SALAH SATU RUMAH SAKIT DI KOTA CIMAHI Septiani, Vina; Kartidjo, Pudjiastuti; Suherman, Linda Purnamawati
Kartika : Jurnal Ilmiah Farmasi Vol 9 No 1 (2024)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v9i1.186

Abstract

Telah dilakukan penelitian pola penggunaan obat kardiovaskular pada pasien penyakit jantung koroner (PJK) di ruang rawat inap salah satu rumah sakit di Kota Cimahi dengan menggunakan desain penelitian analisis deskriptif, yang dilakukan secara retrospektif. Tujuan penelitian ini untuk mengetahui obat-obatan yang digunakan pada pasien jantung koroner di rumah sakit tersebut. Sumber data penelitian adalah rekam medik pasien ruang rawat inap periode Oktober – Desember 2017. Hasil menunjukkan pasien kasus PJK sebanyak 42,04% berusia >60 tahun. Obat-obat dengan frekuensi penggunaan yang tinggi pasien PJK yaitu antithrombosis (ticagrelor 75,16%, fondaparinux 64,97%, dan asam asetil salisilat 29,30%), obat manajemen lipid (atorvastatin 70,06%), beta blocker (bisoprolol 70,70%), ditambah obat golongan diuretik (furosemid 72,61%) yang diberikan untuk penyakit penyerta. Studi ini menunjukkan bahwa penggunaan obat-obatan pada pasien sesuai dengan tatalaksana terapi PJK dari PERKI (Perhimpunan Dokter Spesialis Kardiovaskular Indonesia) Tahun 2018. Kata kunci:  Obat kardiovaskular, pjk, retrospektif.   Abstract The research about uses pattern of cardiovascular drugs for coronary artery disease patients at in-patient department one hospital in Cimahi City was done retrospectively use descriptive analysis design. The aim of this study was to determine the drugs used in coronary artery disease. Data source was medical record of patient who treated at in-patient department period October – December 2017. Result show that 42,04% CAD patients were over 60 years old. The most common drugs that administered to CAD patients were antithrombosis (ticagrelor 75,16%, fondaparinux 64,97%, and acetyl salicylic acid 29,30%), lipid management (atorvastatin 70,06%), beta blocker (bisoprolol 70,70%), and also diuretics (furosemid 72,61%) for co-morbidities. This study shows that the patient's medication use is in accordance with the CHD therapy management from PERKI (Indonesian Heart Association) in 2018. Keywords: Cardiovascular drugs, chd, retrospective.

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