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Fakultas Farmasi UMI, Kampus II UMI, Jl. Urip Sumoharjo No.225, Panaikang, Panakkukang, Kota, Makassar,, Panaikang, Kec. Panakkukang, Macassar, Sulawesi Selatan 90231
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MPSJ
Published by Universitas Muslim Indonesia
ISSN : -     EISSN : 29870887     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Makassar Pharmaceutical Science Journal merupakan salah satu jurnal yang dikelola oleh Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Maret 2023. Makassar Pharmaceutical Science Journal merupakan jurnal ilmiah yang terbit secara on-line dan menerbitkan artikel atau karya ilmiah hasil penelitian dalam bidang farmasi sains.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 100 Documents
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PROFIL PENYIMPANAN OBAT DI INSTALASI FARMASI RSUD ANDI DJEMMA MASAMBA, KABUPATEN LUWU UTARA achyar, lukman; Aztriana, Aztriana; Ririn, Ririn
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 3 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i3.88

Abstract

Pharmaceutical services, such as management including drug storage, must be considered because the treatment of various types of drugs or preparations is not the same. Drug storage is highly essential stage to maintain the quality of medicines, that drug storage must ensure the quality and safety of drugs in accordance with pharmaceutical requirements. The purpose of this study was to determine the profile of drug storage at Pharmaceutical Installation of Andi Djemma Masamba Hospital, North Luwu Regency and its compliance with applicable regulations in Indonesia. This research conducted qualitative and quantitative methods. The informants in this study consisted of the Head of Pharmaceutical Installation, Accompanying Pharmacist, and Head of Pharmacy Installation Warehouse of Andi Djemma Masamba Hospital, North Luwu Regency. The data were collected from observation, in-depth interviews, and data analysis. Presentation of conformity regarding facilities and infrastructure was found 100%. Next, the presentation of the storage place of narcotics, psychotropic substances and precursors was classified 100%. However, the presentation of drug storage methods was 88.8% which confirmed drugs were not arranged based on therapy class. The percentage of high alert drug storage methods of 80% was identified not to use the tall man lettering method. at last, presentation of 100% stock card recording has been performed on every drug mutation process.
UJI AKTIVITAS ANTIBAKTERI FUNGI ENDOFIT PADA DAUN SENGGANI (Melastoma malabathricum L.) ASAL LAMPARA MONCONGLOE TERHADAP BAKTERI PENYEBAB INFEKSI SALURAN PENCERNAAN Hamdani, Nina; Kosman, Rachmat; Rusli, Rusli
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 3 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i3.91

Abstract

Senggani leaf (Melastoma malabathricum L.) is a plant that has antibacterial activity. The purpose of this study was to determine the isolate of the endophytic fungus senggani leaves (Melastoma malabathricum L.) which has antibacterial activity against digestive tract bacteria using the TLC-Bioautography method. The results of this study showed two isolates of senggani leaf endophytic fungi (Melastoma malabathricum L.). IFDS 6 obtained spots with Rf value = 0.58 for Eschericia coli bacteria, Rf value 0.67 for Vibrio cholerae, Salmonella typhi and Shigella dysentriae bacteria. Meanwhile, IFDS 8 obtained spots with an Rf value 0.78 on the bacteria Eschericia coli, Vibrio cholerae, Salmonella typhi, and Shigella dysentriae
Identifikasi Gugus Fungsi Limbah Minyak Trafo yang Digunakan sebagai Minyak Obat Luka Menggunakan FTIR Hidayanti, Nurul; Rahmawati, Rahmawati; Maryam, St.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.92

Abstract

Communities living close to PLN empirically use waste transformer oil as a medicine for wounds such as cuts or cuts and burns such as being exposed to oil or hot cooking utensils. Transformer oil has the main function as an insulating medium and as a coolant. This study aims to determine the chemical components contained in transformer oil waste by using FTIR. The results of research on transformer oil waste using the FTIR method showed that there were carboxyl functional groups, amide groups, aromatic rings, nitro groups and alkyl groups.
Aktivitas Antibakteri Fraksinasi Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius) Terhadap Bakteri Escherichia coli Menggunakan Metode KLT-Bioautografi Latif, Safira Kartika Handayani; Naid, Tadjuddin; Fitriana, Fitriana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 3 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i3.93

Abstract

Fragrant pandan leaves (Pandanus amaryllifolius) have antibacterial abilities, which have secondary metabolites of alkaloids, flavonoids, tannins and saponins. The purpose of this study was to determine the antibacterial activity of extract fractionation from pandan leaves (Pandanus amaryllifolius) against Escherichia coli bacteria. This study used fragrant pandan leaf simplicia (Pandanus amaryllifolius) and extracted using the maceration method with 96% ethanol solvent and evaporated with a rotavapor, after which it was fractionated with ethyl acetate solvent and evaporated again using a rotavapor. The ethyl acetate fraction of fragrant pandan leaves (Pandanus amaryllifolius) was subjected to a screening test with a concentration of 2% against Escherichia coli bacteria, and a TLC-Bioautography test was carried out followed by identification of the chemical components. The result of the 2% concentration screening test on the ethyl acetate fraction of fragrant pandan leaves (Pandanus amaryllifolius) showed activity against Escherichia coli bacteria. TLC-Bioautography test result showed activity on Escherichia coli bacteria with Rf values of 0,94 and 0,65. The result of chemical identification of the ethyl acetate fraction of fragrant pandan leaves (Pandanus amaryllifolius) were positive for containing chemical compounds of flavonoids and tannins which can be used as antibacterials.
Profil Peresepan Obat Diabetes Melitus di RSUD Prof. Dr. H. M. Anwar Makkatutu Kab.Bantaeng Periode Agustus – Oktober 2022 hayat, Nur; Herman, Hendra; Zulkarnain, Iskandar
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 3 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i3.94

Abstract

Diabetes mellitus (DM) is a progressive chronic disease characterized by the body's inability to metabolize carbohydrates, fats and proteins, causing hyperglycemia (high blood sugar). At Prof. Hospital Dr. H. M. Anwar Makkatutu Diabetes Mellitus is a disease that has the highest prevalence based on previous observations. The purpose of this study is to obtain data on prescribing profiles through administration screening, pharmaceutical screening and clinical screening on diabetes mellitus drugs given to patients at Prof. Hospital. Dr. H. M. Anwar Makkatutu, Bantaeng Regency for the period August-October 2022. The research method used is descriptive. The population used was all diabetes mellitus prescriptions (255 recipes) during the study period. Administrative screening showed that 100% of prescriptions did not include height. Pharmaceutical screening yielded 100% of prescriptions did not include instructions for using the drug. Clinical screening found potential drug interactions in 69 cases. Of the 69 cases of interaction that occurred, 89.86% were moderate. The conclusion of this study is the profile of diabetes mellitus drug prescribing in patients at Prof. Hospital. Dr. H. M. Anwar Makkatutu, Bantaeng Regency, has not met the standards of pharmaceutical services in hospitals.
PENETAPAN KADAR FLVONOID EKSTRAK ETANOL BIJI ALPUKAT (Persea americana Mill.) DENGAN MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-Vis RISMA, WA ODE; Abidin, Zainal; Rahmawati, Rahmawati
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 3 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i3.96

Abstract

Avocado (Persea americana Mill.) is a plant that can thrive in tropical areas such as Indonesia. The use of avocado (Persea americana Mill.) as a medicinal plant has been widely used. People usually use avocado seeds as traditional medicine. Avocado seeds (Persea americana Mill.) are plants that contain flavonoid compounds. This study aims to determine the levels of flavonoids in the ethanol extract of avocado (Persea americana Mill.) seeds using the UV-Vis spectrophotometry method. This research was conducted experimentally with qualitative and quantitative methods using UV-Vis spectrophotometry. The results showed that the average flavonoid content of the ethanol extract of avocado seeds was 46.953 mgQE/g extract.
PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK ETANOL DAUN TANAMAN JONGI (Dillenia serrata) MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-VIS Ananda, Savitri; Pratama, Mamat; Baits, Muzakkir
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 3 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i3.101

Abstract

Jongi leaves (Dillernia serrata) is a type of medicinal plant which is used as an anti-inflammatory, antioxidant, antimicrobial, antitumor, anti-ulcer, immunoprevention, cancer chemoprevention, medicine for thrush, vomiting blood, fever, and wound medicine because it contains polyphenolic compounds, such as tannins and flavonoids. This study aims to determine the total flavonoid content of jongi leaves (Dillenia serrata) using the UV-VIS spectrophotometry method. This type of research is laboratory experimental using a spectrophotometer method based on the determination of extract levels and quarcetin standards. The stages of this research began with sample preparation, qualitative testing of flavonoid compounds, and ended with the determination of total flavonoid content of the sample and quarcetin standard. This study obtained results that positive jongi leaf extract contained flavonoids based on the results of identification using FeCl3 reagents and on the results of quantitative testing using UV-VIS spectrophotometry jongi fruit extract had a percentage of flavonoid content of 16.8633%.
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Gaharu (Aquilaria malaccensis) Dengan Menggunakan Metode KLT-Bioautografi Amri, Andhika Ulil
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 4 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i4.102

Abstract

The gaharu plant (Aquilaria malaccensis) has antibacterial properties. The chemical compounds contained in gaharu leaves are flavonoids, alkaloids, and tannins. This study aims to determine the antibacterial activity of the ethanol extract of gaharu (Aquilaria malaccensis) leaves. In this study, gaharu leaf simplicia was extracted using the maceration method with 96% ethanol solvent, after which a liquid extract was obtained and then evaporated using a rotary evaporator to obtain a thick extract. After obtaining the thick extract, a screening test was carried out with concentrations of 0.1 and 0.5% against 3 test bacteria namely Staphylococcus aureus, Pseudomonas aeruginosa, Propionibacterium acnes. Then proceed with TLC-Bioautography testing using chloroform: methanol (1: 4) eluent and then proceed with the identification of the components of the chemical compound. The results of the screening test showed that the ethanol extract of gaharu leaves (Aquilaria malaccensis) showed activity against 3 test bacteria at a concentration of 0.5%. The results of the TLC-Bioautography test showed that there was 1 spot produced with an Rf value of 0.65 against the bacteria Staphylococcus aureus, Pseudomonas aeruginosa, Propionibacterium acnes. The results of identification of the chemical components of the ethanol extract of gaharu leaves (Aquilaria malaccensis) gave positive results containing flavonoids, alkaloids, and tannins. Based on the activity of the ethanol extract of gaharu leaves (Aquilaria malaccensis) it has potential as an antibacterial.
Analisis Kandungan Rhodamin B Pada saus Tomat Yang Beredar DiKabupaten Wajo Kecamatan Belawa Menggunakan Metode Spektrofotometri UV-Vis Hudayanti, Andi Isti; Widiastuti, Harti; Suhaenah, Asriani
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.104

Abstract

Rhodamin B is a synthetic dye that is used as a dye for the textile industry which is dangerous. Rhodamin B is often misused as a food and cosmetic coloring agent, where Rhodamin B can cause irritation to the digestive tract, poisoning and can even cause cancer. This study aims to determine the presence or absence of Rhodamin B content in tomato sauce samples circulating in Wajo District, Belawa District. In this study used six samples marked with S1, S2, S3, S4, S5, and S6. Qualitative analysis used the TLC test and quantitatively for positive samples used the Uv-Vis spectrophotometry method. From the research results, it was found that S1, S2, S3, S4, S5 were negative for Rhodamin B while S6 was positive for Rhodamin B where the Rf value was 0.68, the color of the pink stain matched the Rhodamin B comparison.
PROFIL PENYIMPANAN OBAT DI INSTALASI FARMASI RUMAH SAKIT ANTAM POMALAA Febryanti, Nafa
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 4 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i4.105

Abstract

ABSTRACT Drug storage is oneof the stages of management in pharmaceutical dosage forms to maintain drug quality, as well as to reduce the risk of loss and damage. A bad storage system can result in drugs being damaged and ineffective in treatment. The suitability of drug storage has been regulated in pharmaceutical standards in hospitals. This study aims to get an overview of the profile of drug storage in the pharmacy installation of Antam Pomalaa Hospital, Kolaka regency. This research is a descriptive study by collecting data from interviews and observations in the drug storage room at the pharmacy instllation of antam pomalaa hospital, kolaka regency. the research result have been calculated and analyzed using percentage analysis which result in facilities and infrastructure obtaining a conformity percentage of 84,2%. Compilation of drug stock in the storage warehouse obtains a conformity percentage og 83.3% and in recording drug stock cards obtains a conformity percentage of 100%. The total percentage is included in the good category according to the applicable conformity standards.

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