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Journal of Medicine and Health
Published by Universitas Kristen Maranatha
ISSN : -     EISSN : 24425257     DOI : 10.28932/jmh
Core Subject : Health,
Medicine & Pharmacology Public Health
Journal of Medicine and Health (JMH) focuses on contributing towards science and research development that can be accessed by researchers and academic practitioners. Journal of Medicine and Health (JMH) is an open access journal, published biannually on every February and August. JMH receives original research articles, case report, and review articles related to biomedical sciences, clinical medicine, public health sciences, nutritional sciences, and medical herbs sciences. Articles should be written in good English or Indonesian language. All articles will be processed through peer review process.
Arjuna Subject : Kedokteran - Patologi dan Kedokteran Kesehatan
Articles 228 Documents
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The New Perspective of Exercise as a Breast Cancer Therapy Alvin Wiharja
Journal of Medicine and Health Vol 1 No 3 (2016)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v1i3.524

Abstract

The prevalence of cancer increases each year, from 4.7‰ in 2007 to 5 ‰ in 2013. InWest Java, the prevalence of cancer is quite high at 1.0 ‰. Obesity becomes a risk factor forcancer. Exercise is aimed to solve the obesity problem, prevent and improve the cancer patientcondition, as well as improve the quality of life of cancer patients. Exercise plays a role in thetreatment of cancer patients. The potential benefits obtained during and after exercise areincrements of strength, speed, muscle mass, physical functions, range of motions, immunefunctions, the average completeness of chemotherapy, improved body shape, moods andconfidence. For patients diagnosed with breast cancer, exercise acts as a therapeutic to preventthe disease and its etiology factors (hormonal theory, the theory of immunity and inflammationtheory). Applying the proper exercise (frequency, intensity, type and time) in cancer patientswould improve the physical performance which is impaired due to cancer. Exercise canimprove levels of fitness, muscle strength, quality of life and fatigue in patients with cancersurvivors. Diagnosis and management of cancer can decrease the system performance organsand it would be upgrade by good exercise.Keywords: breast cancer,exercise
Prevention and Treatment of Early Childhood Caries (ECC) Jeffrey .
Journal of Medicine and Health Vol 1 No 3 (2016)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v1i3.525

Abstract

Early Childhood Caries (ECC) is a chronic disease that can be prevented. It commonlyaffects children involving in one or more decayed (with lesions or not) teeth, missing teeth (dueto caries), or teeth with fillings in children aged under 71 months. The disease is sometimesoverlooked, but this condition usually affects the general health of children. Early detection ofEarly Childhood Caries (ECC) can prevent problems which are harmful to children. Therefore,the ECC must be prevented and for teeth that have had dental caries they should be givenproper treatment so as not to worsen and affect the quality of life in children. Prevention of thisdisease is a significant component in any health program to prepare for the optimal basis forthe oral health of children. This condition will become a serious health problem if not handledproperly, and it is a major health problem for health providers throughout the world.Primarypreventive must be initiated since a woman getting pregnant.Keywords: Early Childhood Caries (ECC), prevention, treatment
Peer Reviewers of JMH Volume 1 Number 3 February 2016 Editorial Editorial Team
Journal of Medicine and Health Vol 1 No 3 (2016)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v1i3.526

Abstract

We would like to thank our peer reviewers for the precious contributions in providing clinical,scientific, and methodological expertise for JMH Volume 1 Number 3. We appreciate everythoughtful review of submitted manuscripts and for making important contributions to improve thescientific quality of articles published in JMH. We listed the names in alphabetical order.Dr.dr.Agung Budi,Sp.BSdr. Amaylia Oehadian,Sp.PD-KHOMProf. Dr. Ambrosius Purba, dr.,MS.,AIFOdr.Cherry Azaria, M.Kesdr.Decky Gunawan,M.Kesdr. Djaja Rusmana, M.Si.dr Dono Pranoto, SpB., M.Kesdr. Frecillia Regina,Sp.A.,IBCLCDr. dr. Hana Ratnawati, M.Kes., PA(K)Ingrid S. Surono, PhDProf.dr. Jeanne A. Pawitan, MS, PhDdr. Justin Ginting, Sp.Raddr. Laella Kinghua Liana,Sp.PA,M.Kesdrg. Linda Sari Sembiring, Sp.KGADr. dr. Meilinah Hidayat, M.KesProf. Dr. dr. M. Nurhalim Shahibdrg. Ruslin,Sp.BM.,M.KesProf. Dr. dr. Susy Tjahjani, M.KesProf. dr. Wahyuni Lukita Atmadja, PhD.dr. Yenni Limyati, Sp.KFR.,M.Kes
The Effect of Jati Belanda Leaves (Guazuma ulmifolia Lamk.) Ethanol Extract on Microscopic Features of Atherosclerotic Animal Model’s Aorta Ryan J. Permana; Cherry Azaria; Rosnaeni Rosnaeni
Journal of Medicine and Health Vol 1 No 4 (2016)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v1i4.527

Abstract

“Jati Belanda” leaves (Guazuma ulmifolia Lamk.) possesses antidyslipidemia effect and in this study we assessed the effect of "Jati Belanda” leaves ethanol extract in delaying the progression of atherosclerosis in aorta of the rats.Thirty atherosclerosis animal models were divided into six groups, which are three variant dose of “Jati Belanda” leaves (EEDJB 1-2-3), standard control (SC), negative control (NC) and Comparative control/ CC (simvastatin). The parameters measured were the wall thickness and lumen diameter (both in mm), and the amount of foam cells. The result for Kruskal Wallis test showed highly significant differences (p=0.00) of wall thickness Dose2 (0.056 mm) and Dose3 (0.056 mm) compared to NC (0.075 mm) and non-significant compared to CC (0.055 mm). ANOVA result for lumen diameter, p=0.773.  ANOVA result for foam cells amount, p=0.000, Duncan test showed significantly different between EEDJB and NC group.It is concluded that “Jati Belanda” leaves ethanol extract reduced aortic wall thickness and the amount of foam cells, but did not increase lumen diameter on the athersclerotic aorta, and had an equal therapeutic effect compared to simvastatin in delaying the progression of atherosclerosis. Keywords: atherosclerosis, Jati Belanda, wall thickness, lumen diameter, foam cell
The Effect of Ethanol Extract from Mangosteen Pericarps towards Parasitemia in Plasmodium berghei-Inoculated Mice Debora R. Marito; Susy Tjahjani; Khie Khiong
Journal of Medicine and Health Vol 1 No 4 (2016)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v1i4.528

Abstract

Mangosteen pericarps contains fenolic antioxidant, such as xanthone that acts as free radical scavenging substances and preventing heme polymerization. In this research we evaluated the effect of ethanolic extract of mangosteen pericarps on the parasitemia in Plasmodium berghei-inoculated mice and compared its antimalarial activity with artemisinin monotherapy in reducing the parasitemia in Plasmodium berghei-inoculated mice. Deutschland Denken Yoken (DDY)  mice were randomly divided into 5 groups and inoculated by Plasmodium berghei and given 0.1 mL aquadest (KN), 0.1 mg of artemisinin (KP), 2.5 mg (E1), 0.5 mg (E2) and 0,1 mg (E3) of ethanolic extract from mangosteen pericarps in 0.1 mL aquadest in 3 days. The parasitemia was observed on one day before the treatment, namely on the first day and on the day after the last treatment. We found a highly significant decrease highly significant decrease of the parasitemia in each treatment group compared to the Negative Control group (p < 0.01), and the decrease of parasitemia level in E1 group is similar to the artemisinin monotherapy group (p < 0.05).  Keywords: ethanol extract of mangosteen pericarps, artemisinin, Plasmodium berghei, malaria
The Preventive Effect of Fig Leaves’s (Ficus carica L.) towards Colon Histopathological Feature and IL-6 Serum Level on Ulcerative Colitis Induced Mice Hartini Tiono
Journal of Medicine and Health Vol 1 No 4 (2016)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v1i4.529

Abstract

Ulcerative colitis is a chronic inflammatory disease mainly affects sigmoid colon and rectum. The inflammation process will activate NF-κB and leads to proinflamatory cytokine release such as Interleukin-6 (IL-6). Fig leaves contain a high level of flavonoid which can prevent NF-κB activation, and further inhibits IL-6 secretion. This research aims to see the preventive effect of methanolic extract of fig leaves towards colon histopathological feature and IL-6 serum level on ulcerative colitis induced mice. Balb/C male mice were randomly assigned into 5 groups (n=5). The treatment groups were dextran suphate sodium (DSS) control group (group I), methanolic extract of Fig leaves dose 28 mg/ day control group (group II), and methanolic extract of Fig leaves dose 7 mg/ day (group III), 14 mg/ day (group IV), and 28 mg/ day (group V) for 14 days, which at the 8th till 14th day were given DSS to induce colitis. The results showed that both of colon mucosal damage and IL-6 serum level of group I were significantly different from other groups (p=0,029). In  conclusion, the methanolic extract of Fig leaves can improve colon mucous damage and decrease IL-6 serum level on ulcerative colitis-induced mice. Keywords: ulcerative colitis, fig leaves, colon mucousal damage, interleukin-6
Subchronic Treatment of Combination Extract Detam 1 Soybean and Jati Belanda Leaves has No Toxic Effect on Function, Weight, and Histopathological of Wistar Rat Kidney Meilinah Hidayat; Sijani Prahastuti; Vibiola Chikita; Dewi Safitri; Siti F. Rahmawati; Andreanus A. Soemardji
Journal of Medicine and Health Vol 1 No 4 (2016)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v1i4.530

Abstract

The combination of Detam 1 soybean and Jati Belanda leaves proved to have effect of weight loss. Since it will become longterm using, toxicity effectvresearch is needed.  This study was conducted to determine the effect of subchronic combination of ethanol extract of soybean Detam 1 (EEDS) and Jati belanda (EEJB) on kidney function, with parameters: urea and creatinine, macroscopic and histopathological of kidney. This study were conducted on 120 Wistar rats (60 males, 60 females), 90 days (treatment group) and 120 days (satellite group). Rats were divided into six treatment groups. Test results of urea and creatinine levels of all treatment groups was lower than control group (p <0.05). The treatment turned out to have a good effect on kidney function. Kidney weight of all groups showed no significant difference with the control group (p> 0.05). Histopathological score interpretation’s result of low dose group male and female kidney rats were not disturbed. In conclusion, the combination of EEDS and EEJB  have a good effect on kidney function, did  not lead to changes in organ weight and at low doses did not cause disturbance of  renal histopathology. Key words: combination of soybean jati Belanda, subchronic treatment, kidney function, kidney’s  weight, kidney’s histopathology
Prevalence and Characteristics of Liver Cancer Patients in Immanuel Hospital Bandung within January 2013 until December 2014 Period Achmad R. Permadi; Hana Ratnawati; Teresa L. Wargasetia
Journal of Medicine and Health Vol 1 No 4 (2016)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v1i4.531

Abstract

Liver cancer is the fifth most common cancer in Indonesia. This research is to find out the prevalence and characteristics of liver cancer patients in Immanuel Hospital Bandung within the January 2013 until December 2014 period based on age, gender, clinical symptoms and predilections. This study was a descriptive verificative research with data retrieval of patients medical records that have been diagnosed with liver cancer that were hospitalized in Immanuel Hospital Bandung within January 2013 until December 2014 period. The study showed that the liver cancer patient prevalence in Immanuel Hospital Bandung within the period of January 2013 until December 2014 was 46 people. Characteristics of liver cancer patients in Immanuel Hospital Bandung within January 2013 until December 2014 period showed that the most liver cancer patients were male, compare with female with ratio 4:1, the most common age group of 56-65 years old, the most common clinical symptoms were abdominal pain with or without reffered pain to the right scapular bone and the most common predilection was right lobe of the liver. Key words: liver cancer, patients' characteristics, prevalence 
Height Estimation Based on Foot Length and Breadth in Children, Teenager, and Adult in Bandung City, Indonesia Sani Tanzilah; Noorman Herryadi; Andri A. Rusman
Journal of Medicine and Health Vol 1 No 4 (2016)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v1i4.532

Abstract

Stature estimation is important for forensic identification, particularly in dismembered body. The equation used to estimate the height of a population is not necessarily applicable to other populations (population spesific). This study was conducted to generate the linear regression equation for stature estimation based on foot length and foot breadth on the population in the city of Bandung.  This cross-sectional study is conducted to 908 people, consisting of three age groups (children, adolescents, adults), in the city of Bandung. Sampling was done by multistage sampling. The stature was measured using a stadiometer SECA 213, right foot length (RFL), right foot breadth ( RFB), left foot length (LFL), and left foot breadth (LFB) were measured using sliding calipers. Data were analyzed with SPSS version 21.0 for Windows. There is correlation between height with the RFL, RFB, LFL, and LFB. In contrast to the group of teenagers and adults, there is no boys-girls difference between height, RFL, RFB, LFL, and LFB. 21 regression equation for stature estimation based on the foot size. Stature estimation can be done using the linear regression equation based on the foot length and foot breadth, according to population, gender, and age of the subject being examined. Key words: height estimation, foot length, foot breadth
The Probiotic Effect towards Aspirin-induced Gastric Ulcer Healing Process as Measured by Mucous Thickness, Reepithelization, Gastric Glands Formation, and Angiogenesis in Animal Model Teresa Lucretia; Achadiyani Achadiyani; Sadeli Masria
Journal of Medicine and Health Vol 1 No 4 (2016)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v1i4.533

Abstract

Gastric Ulcer is a common side effect of Non-Steroid Anti Inflammatory Drugs (NSAIDs) use such as Aspirin. Probiotic has many benefits especially for the alimentary system, but the effect on gastric ulcer have yet to be explored. In this research we aimed to find the probiotic effect on histological structure changes during aspirin induced gastric ulcer healing process in animal model. This was simple random sampling animal experimental laboratory, that divided Wistar Rats into two main groups. Both groups were induced with Aspirin (300mg/Kg BW) per oral, once daily for three consecutive days,and subsequently the test group were given probiotic suspension (cfu >108/gr) per oral, once daily, for 14 days. Each subgroups were sacrified serially at day 0, 3, 7, 14. The gaster were collected and processed for histology examination. Better histological structures were shown in the test group at day 14. MANOVA result showed probiotic's effect in enhancing histological structure changes during gastric ulcer healing process. Better histological structure changes were observed in mucus thickness; reepitelization, gastric glands formation, and angiogenesis process of the test group. As a conclusion, probiotic enhanced mucus thickness, reepitelization, glands remodelling, and angiogenesis in Aspirin induced gastric ulcer healing process in animal model. Key words: probiotic, gastric ulcer, histological structure, aspirin, healing process

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