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Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Health Professions
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 1,276 Documents
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Asparaginase untuk Terapi Leukemia Limfoblastik Akut pada Anak: Analisis Lawrenti, Hastarita
Cermin Dunia Kedokteran Vol 52 No 3 (2025): Oftalmologi dan Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i3.1379

Abstract

Acute lymphoblastic leukemia (ALL) is the most frequently diagnosed childhood malignancy. The five-year survival rate in high-income countries is higher than in low-income countries. Asparaginase remains the cornerstone of treatment in childhood ALL. There are several types of asparaginase available worldwide, including native E. coli asparaginase, pegasparaginase, Erwinia asparaginase, calaspargase pegol, and recombinant Erwinia asparaginase. Hypersensitivity reactions are the main complication related to asparaginase. The other concern is the development of anti-asparaginase antibodies which results in silent inactivation with no therapy benefit. Therapeutic drug monitoring is required in pediatric patients with ALL undergoing asparaginase therapy.
Gangguan Sistem Penglihatan pada Pasien Pre-eklampsia/Eklampsia: Tinjauan Pustaka Ekaputri, Maria Vania Tri
Cermin Dunia Kedokteran Vol 52 No 3 (2025): Oftalmologi dan Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i3.1383

Abstract

Pre-eclampsia and eclampsia are constrictive vasculopathy diseases which may involve retina, retinal blood vessels, and brain cortex, causing mild to severe visual complications and even blindness. These problems can be prevented with regular early detection or comprehensive examination. Appropriate and fast treatment can reduce the risk of more severe damage and even permanent disability.
Menjembatani Kesenjangan dalam Manajemen Dislipidemia di Indonesia Melalui Strategi ACS Europath: Analisis Antonius, Richard; Muzakkir, Akhtar Fajar
Cermin Dunia Kedokteran Vol 52 No 4 (2025): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i4.1384

Abstract

Dyslipidemia is a significant global public health concern, particularly in Indonesia. Current dyslipidemia guidelines stated the management should be done with a combination of lifestyle and pharmacological interventions. Treatment with lipid lowering agents should be initiated early for better prognostic benefit. ACS Europath IV project emphasizes the importance of early intensification of lipid-lowering therapy to reduce the risk of recurrent cardiovascular events and improve patient outcomes. This literature review the current state of dyslipidemia management in Indonesia and discussing the potential role of ACS Europath strategies in improving patient outcomes.
Penyelamatan Tungkai dengan Prosedur Darrach dan Teknik Tulang Tunggal pada Tumor Sel Raksasa pada Ulna (Campanacci Tipe 3): Laporan Kasus Saputra, Rhyan Darma; Sadewa, Daffa; Dzikri, Dykall; Budiyanto, Sandya Naufal; Aji, Febriagi Bayu
Cermin Dunia Kedokteran Vol 52 No 5 (2025): Kardiologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i5.1394

Abstract

Introduction: Giant cell tumor of bone (GCTB) is a rare, benign but locally aggressive tumor that uncommonly afects distal ulna. Case: This case is a 30-year-old female with worsening pain, swelling, and limited wrist motion. Imaging studies revealed cortical destruction and soft tissue infltration characteristic of an aggressive GCTB. Campanacci type 3 GCTB of the distal ulna was diagnosed and managed through limb salvage surgery using a combination of Darrach procedure and single bone technique.This combined approach aims to achieve tumor clearance while preserving limb function. Post-operative management included soft tissue closure using an abdominal fap. Conclusion: The case highlights the challenges in managing aggressive GCTBs of the distal ulna and demonstrates a viable limb salvage strategy. Long-term follow-up is recommended to evaluate functional outcomes and to monitor for recurrence, because tumor’s aggressive nature.
Surveillance dan Penyebaran Penyakit Tangan, Kaki, dan Mulut (HFMD): Tinjauan Pustaka Adrian, Reza
Cermin Dunia Kedokteran Vol 51 No 10 (2024): Infeksi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i10.1434

Abstract

Hand, foot, and mouth disease (HFMD) is a common viral illness primarily affecting children. HFMD is caused by various types of coxsackievirus and enterovirus; the main causes are coxsackievirus A16 and enterovirus A71. This article discusses HFMD surveillance and its spread in several countries, including China, Singapore, and Indonesia, aiming to understand the surveillance processes and HFMD distribution to formulate effective prevention and management strategies.
Tinjauan Imunologi pada Fenomena Non-Responder terhadap Vaksinasi Hepatitis B: Analisis Arjana, Adika Zhulhi; Devita, Ninda
Cermin Dunia Kedokteran Vol 52 No 4 (2025): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i4.1437

Abstract

Hepatitis B vaccine has been highly effective in preventing HBV infection. However, a subset of individuals fails to develop adequate protective antibodies after complete vaccination series (anti-HBs ≥ 10 mIU/mL), termed as non-responders. Non-responder phenomenon is influenced by a complex interplay of genetic, immunological, and environmental factors. This narrative review aims to delve into the immunological aspects of the non-responder phenomenon, exploring the factors influencing vaccine response, the immunological mechanisms involved, and potential approaches to managing and overcoming non-responders.
Efektifitas Citicoline dalam Meningkatkan Fungsi Kognitif: Analisis Dermawan, Bagus; Ardhini, Rahmi; Puspita Wati, Arinta
Cermin Dunia Kedokteran Vol 52 No 4 (2025): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i4.1458

Abstract

Latar belakang: Kejadian gangguan kognitif meningkat seiring dengan pertambahan usia ataupun karena gangguan organik otak. Citicoline diduga dapat memperbaiki fungsi kognitif. Tulisan ini meninjau efektivitas citicoline dalam meningkatkan fungsi kognitif. Metode: Pencarian sistematis pada 3 database, yaitu PubMed, Scopus, dan EBSCO, sesuai kriteria inklusi dan eksklusi. Artikel yang terpilih ditelaah kritis dan dianalisis lebih lanjut. Hasil: Dalam analisis terakhir, didapatkan 2 artikel untuk telaah kritis. Satu studi populasi sehat menunjukkan perbaikan fungsi kognitif terutama pada domain memori setelah pemberian citicoline 500 mg/hari selama 3 bulan, 1 studi lain pada populasi pasca-stroke iskemik menunjukkan perbaikan fungsi kognitif terutama pada domain atensi, eksekutif. dan orientasi temporal setelah pemberian citicoline 1.000 mg/hari selama 12 bulan. Simpulan: Pemberian citicoline dapat memperbaiki fungsi kognitif, baik pada populasi sehat maupun populasi pasca-stroke iskemik.
Keamanan Kranberi dalam Pencegahan Infeksi Saluran Kemih: Analisis Judian, Terence
Cermin Dunia Kedokteran Vol 52 No 3 (2025): Oftalmologi dan Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i3.1477

Abstract

Urinary tract infection is a common disease with high recurrence. UTI is usually treated with antibiotics, however high bacteria resistance towards first-line antibiotic treatment is becoming a health issue. Cranberries have been shown to prevent the adhesion of bacteria to host cell, hence preventing UTI. This systematic review aimed to determine the effectivity and safety of cranberry for prevention of urinary tract infection. Systematic Review was done with search engine from Google Scholar, PubMed, and ScienceDirect, starting with forming clinical question using PICO framework. Studies included was selected based on inclusion and exclusion criteria. The outcomes extracted from each study are the effectiveness and safety of cranberries in UTI prevention. Eight studies were reviewed, seven studies concluded that cranberries can significantlyprevent UTI, while 1 study found that the result was not significant. Three studies reported minimal adverse effect in a small percentage of patients. Cranberries can reduce the incidence of recurrent UTI with minimal adverse effect. PACs (proanthocyanidins) in cranberries can prevent bacteria adhesion, therefore preventing colonization of the bacteria in the urinary tract. Further research on dose and duration are required.
Upaya Pencegahan Hand, Foot, and Mouth Disease Berat Melalui Vaksinasi Enterovirus 71: Analisis Aditya, Thomas
Cermin Dunia Kedokteran Vol 51 No 10 (2024): Infeksi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i10.1492

Abstract

Indonesian Ministry of Health detected an increasing trend in suspected hand, foot, and mouth disease (HFMD) in all provinces in Indonesia in 2024. Enterovirus 71 (EV71) is the main cause of severe HFMD and death. There has been no specific therapy for EV71. EV71 vaccine has been developed and approved by regulatory agencies in various countries (China, Thailand, and Indonesia) for the prevention of HFMD due to EV71. Multi-center phase IV study showed a good safety profile with an AEFI of 1,079%. Most AEFIs are grades 1 and 2.
Tolvaptan untuk Hiponatremia Euvolemik dan Hipervolemik: Tinjauan Narasi Judian, Terence; Alexsander, Samuel
Cermin Dunia Kedokteran Vol 51 No 12 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i12.1498

Abstract

Hyponatremia is an electrolyte imbalance disorder commonly found in clinical practice. Hyponatremia is associated with significant mortality and morbidity. Tolvaptan is an orally administered V2 receptor antagonist drug capable of aquaresis without excreting electrolytes, thus increasing plasma sodium concentration. Results from clinical trials showed tolvaptan to be a relatively safe and effective treatment in euvolemia and hypervolemia hyponatremia.

Page 124 of 128 | Total Record : 1276

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