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Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Health Professions
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 1,276 Documents
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Efektivitas Vaksin Influenza terhadap Risiko Komplikasi Pneumonia pada Anak: Analisis Subagio, Devina; Subagio, Devani
Cermin Dunia Kedokteran Vol 52 No 6 (2025): Kesehatan Jiwa
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i6.1691

Abstract

Influenza is an acute respiratory infection (ARI) caused by the influenza virus. World Health Organization (WHO) states that influenza virus infection causes 99% deaths in children under 5 years of age in developing countries. Transmission between individuals is fast because the influenza virus is transmitted through droplets. Symptoms of influenza disease vary; most are mild and self-limiting, but in some cases, it can cause severe complications and have an impact on mortality. Pneumonia is one of the most common complications of influenza, especially in the pediatric population. Influenza vaccination is an effective option for preventing infection and its complications. Several studies have shown that influenza vaccination can reduce influenza cases and the incidence of influenza-related pneumonia hospitalizations.
Penggunaan Vitamin D3 Oral Dosis Tinggi Kristiningrum, Esther
Cermin Dunia Kedokteran Vol 49 No 10 (2022): Oftalmologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v49i10.1718

Abstract

Vitamin D is a fat-soluble vitamin with an important role in various skeletal and non-skeletal physiological functions. Vitamin D deficiency has been found in many countries including Indonesia, and has been associated with an increased risk of various diseases. Vitamin D supplementation or even high-dose vitamin D therapy is often necessary to maintain or to achieve optimal vitamin D status, especially if rapid correction is required and/or as adjunctive therapy for other diseases. Various clinical trials have shown that high-dose oral vitamin D3 therapy is effective and relatively safe for vitamin D deficiency patients.
Flebotomi Pada Penyakit Jantung Bawaan Dewasa Sianotik Nugraha, Ngurah Agung Reza Satria; Susila, I Ketut
Cermin Dunia Kedokteran Vol 52 No 11 (2025): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i11.1211

Abstract

Adult congenital heart disease is a cardiovascular condition that necessitates a comprehensive approach to medical and surgical intervention. In this condition, cyanosis results from a right-to-left shunt, which subsequently causes secondary erythrocytosis and hyperviscosity. Dehydration and iron deficiency can exacerbate the symptoms of hyperviscosity. One proposed strategy for reducingviscosity is phlebotomy. Phlebotomy procedures should be conducted with adequate fluid replacement to prevent acute stroke. While phlebotomy can reduce red blood cell mass and serum viscosity, it should be performed judiciously and not repeatedly to avoid stroke complications. Repeated phlebotomy without appropriate indications may lead to chronic iron deficiency and microcytic erythrocytes, which paradoxically increase the risk of cerebrovascular complications. Indications for therapeutic phlebotomy include moderate to severe hyperviscosity symptoms with hematocrit levels of at least 65% in the absence of dehydration or iron deficiency.The benefits of phlebotomy should only be considered when appropriate indications are met to achieve improved patient outcomes.
Terapi Hiperbarik Oksigen sebagai Tata Laksana Tuli Mendadak: Tinjauan Pustaka Widjaja, Gabriela
Cermin Dunia Kedokteran Vol 52 No 11 (2025): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i11.1312

Abstract

Sudden deafness or sudden sensorineural hearing loss is sensorineural deafness which is an ENT emergency because it can become permanent if not treated immediately. Sudden deafness is characterized by a sensorineural hearing loss of at least 30 dB within less than 72 hours. Most causes of sudden deafness are unknown (idiopathic) so treatment is empirical. The principles of managing sudden deafness are early detection, early diagnosis, and early treatment. The main treatment for sudden deafness is oral steroids, intratympanic, or a combination of both. Hyperbaric oxygen therapy (HBOT) has become a promising adjuvant therapy, working by increasing oxygenation in the perilymph and ischemic cochlear tissue. Several studies have shown that combining HBOT with steroids provides superior results compared to steroid monotherapy, especially in cases of severe deafness and if started within two weeks of symptom onset. Further research is still needed to confirm the effectiveness of hyperbaric oxygen therapy as a treatment for sudden deafness.
Sebuah Laporan Kasus Anemia Hemolitik Autoimun dengan Trombosis Vena Dalam pada Gadis 16 Tahun - Apakah Lupus Eritematosus Sistemik? Laporan Kasus Buchori, Muhammad; Joalsen Mangaratua, Ivan; Corona, Fidel; Sanjaya, Kevin; Mulyani, Laily
Cermin Dunia Kedokteran Vol 52 No 11 (2025): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i11.1371

Abstract

Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disease with various clinical manifestations. Multiorgan involvement is associated with a worse prognosis. SLE in pediatrics is rare, with an estimated incidence of 0.3–0.9 per 100,000 children. Case: A 16-year-old Asian girl was admitted with pain, swelling, and a bluish discoloration with blisters on the right leg for 6 days. She had a history of facial rash, hair loss, and oral ulcer. Doppler ultrasound showed deep vein thrombosis in the right lower extremity with acute thrombosis, with visible soft-material intraluminal thrombus. Coombs test was 4+ positive. Elevated total bilirubin 2.2 mg/dL, indirect bilirubin 0.9 mg/dL, and elevated reticulocyte 5.2%. ANA test result is borderline 0.8, and anti-DS DNA negative. CT angiography showed proximal total occlusion of the right dorsalis pedis artery, DVT along the external iliac vein, femoral vein, and popliteal vein to the proximal 1/3 of the right posterior tibial vein. Diagnosis of an autoimmune disease leading to autoimmune hemolytic anemia and deep vein thrombosis was suspected. Her condition improved after corticosteroids and anticoagulant treatment. Conclusion: A 16-year-old girl was diagnosed with autoimmune hemolytic anemia, deep vein thrombosis, and suspected systemic lupus erythematosus. Early recognition of unusual manifestations of SLE is important.
Hubungan Obesitas terhadap Mortalitas Pasien Gagal Jantung : Hasil Penelitian Dewi, Annisa Oktrivia; Laariya, Tira Alfiani; Arliono, Tri Yunanto
Cermin Dunia Kedokteran Vol 52 No 11 (2025): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i11.1524

Abstract

Introduction: Obesity is a condition of excessive accumulation of body fat. Obesity has a greater risk of death from cardiovascular diseases. Heart failure is a clinical syndrome caused by structural and functional defects of the myocardium that result in impaired ventricular filling or blood ejection. This study was conducted to determine the relationship between obesity and mortality in heart failure patients at a teaching hospital in Yogyakarta. Methods: A cross-sectional quantitative study with an observational analytical research design from the secondary data from medical records of heart failure patients in January 2018–March 2024. Data was analyzed using Fisher’s exact test. Results: A total of 108 patients met the inclusion and exclusion criteria. Data analysis showed a p-value = 0.216 (>0.05). In this study, 61.1% of heart failure patients were male. The results showed that the mortality rate was higher in obese patients (11.1%) compared to non-obese patients (5.55%). Conclusion: There was no relationship between obesity and mortality among heart failure patients.
Beberapa Faktor yang Terjadi pada Gangguan Gizi pada Anak di Puskesmas Maubesi, Nusa Tenggara Timur: Studi Kohort Retrospektif: Hasil Penelitian Saudale, Yunri Steviani
Cermin Dunia Kedokteran Vol 52 No 11 (2025): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i11.1568

Abstract

Introduction: In Indonesia, the incidence of nutritional disorders (malnutrition) in children aged 0–59 months in 2023 reached 8.5%. Methods: A retrospective cohort study was conducted on 48 children in the Maubesi Health Center working area, East Nusa Tenggara, in January–June 2024 to assess the relationship between gender, birth weight and length, number of siblings, place of birth, exclusive breastfeeding, immunization status, medical history, food variation, mother’s age and education, mother’soccupation, mother’s weight before pregnancy, mother’s Hb levels during pregnancy, mother’s history of hypertension and diabetes, and antenatal care (ANC) visits with the incidence of malnutrition and severe malnutrition. Data were obtained from the Integrated SIGIZI application, and children’s nutritional status was measured using the WHO (2006) weight-for-height chart. Results: Theanalysis used Fisher’s exact test and Spearman’s rank correlation test. A significant relationship was found between the number of ANC visits and the incidence of both malnutrition and severe malnutrition (p = 0.001), which showed a weak negative correlation: r(44) = -0.139, p = 0.357. Conclusion: In this study, a negative correlation was obtained between the number of ANC visits andthe incidence of undernutrition and severe malnutrition.
Penyakit Bulosa Autoimun pada Lanjut Usia: Tinjauan Pustaka Putra, Gilang Widratama; Saraswati, Putu Dyah Ayu
Cermin Dunia Kedokteran Vol 52 No 11 (2025): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i11.1572

Abstract

Peningkatan kasus penyakit bulosa pada lanjut usia terkait berbagai faktor. Penuaan menyebabkan penurunan struktur dan integritas kulit, sehingga lebih rentan terhadap penyakit bulosa. Penyakit ini terjadi karena proses penuaan menyebabkan disregulasi system imun yang meningkatkan risiko kondisi autoimun. Penyakit bulosa yang sering terjadi pada lanjut usia biasanya adalah pemfigoid bulosa (kondisi autoimun bulosa) dan pemfigus vulgaris (penyakit kulit yang menyebabkan lepuhan) yang berhubungan dengan morbiditas dan mortalitas yang signifikan. Pemfigoid bulosa ditandai dengan bula subepidermal tegang, sedangkan pemphigus vulgaris ditandai dengan bula suprabasal kendur yang mudah pecah. Pemeriksaan histopatologi dan imunofluoresensi langsung merupakan baku emas diagnosis. Tata laksana penyakit bulosa autoimun pada lansia umumnya sama dengan penyakit bulosa pada umumnya, seperti corticosteroid dan agen imunosupresif. Namun, perlu diberikan tata laksana yang tepat dan efektif serta diberikan perhatian lebih lanjut terhadap risiko polifarmasi dan efek samping obat yang dapat memberikan masalah baru pada pasien lansia, termasuk peningkatan risiko infeksi, steoporosis, dan komplikasi metabolik.
Vaksinasi sebagai Upaya Pencegahan Foodborne Disease pada Anak : Analisis Lubis, Pika Novriani
Cermin Dunia Kedokteran Vol 52 No 11 (2025): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i11.1610

Abstract

Foodborne disease is one of the disease burdens because it can lead to disability and mortality, particularly in children. Hepatitis A and typhoid are the primary causes of foodborne diseases in developing countries. Although the majority will recover, children with hepatitis A can be a source of transmission. Meanwhile, in addition to endemicity in Indonesia, antibiotic resistance to typhoid infections is rising. Vaccination is considered an economic measure to suppress the incidence and transmission of disease, as well as prevent outbreaks. To achieve the effectiveness and efficiency of vaccination, it is essential for the general practitioner to have a comprehensive understanding of the preparations, methods of use, storage, precautions, contraindications, and potential adverse effects of the vaccine. In addition, increased public awareness of the importance of vaccination and the implementation of good food hygiene are factors that support the success of foodborne disease prevention. Public education efforts through health facilities and schools need to be strengthened to expand childhood immunization coverage. Thus, it is hoped that the incidence of hepatitis A and typhoid can be significantly reduced, in line with national and global health program targets to reduce morbidity and mortality rates from vaccine-preventable diseases. 
Gambaran Radiologis Artritis Inflamatori Nathania, Liem Marcella; Ligin, Erina Damayanti
Cermin Dunia Kedokteran Vol 52 No 11 (2025): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i11.1625

Abstract

Arthritis is a common disease that often causes activity limitations. The diagnosis of inflammatory arthritis requires conventional radiography as the primary modality. Assessment of alignment (A), bone (B), cartilage loss (C), demineralization (D), erosion (E), and soft tissue swelling (S) on radiographs is necessary to differentiate the three most common inflammatory arthritides: rheumatoidarthritis, gouty arthritis, and psoriatic arthritis (PsA). Each type of arthritis has characteristic radiological features that are important for diagnosis. Rheumatoid arthritis is characterized by marginal erosion in bare areas, periarticular osteopenia, and uniform joint space narrowing with bilateral symmetrical distribution. Gouty arthritis shows punched-out erosion with overhanging edges, tophi deposits, and normal bone mineralization. Psoriatic arthritis has characteristic marginal erosions accompanied by new bone formation, pencilin- cup deformities, and dactylitis. Understanding the differences in the radiological features of these three diseases is important for establishing an accurate diagnosis and determining appropriate therapy. The combination of radiographic examination with clinical and laboratory data is expected to improve diagnostic accuracy and reduce disease progression.

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