cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Dita Arccinirmala
Contact Email
dorotea.arccinirmala@kalbe.co.id
Phone
+6281905203065
Journal Mail Official
CDK@kalbe.co.id
Editorial Address
Redaksi CDK Gedung Kalbe, gedung 2 lantai 2 Jl. Letjen Suprapto Kav. 4. Cempaka Putih - Jakarta 10510
Location
Unknown,
Unknown
INDONESIA
Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Health Professions
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 1,312 Documents
 121   122   123   124   125 
Konsentrasi Fenolik Total dan Aktivitas Antioksidan dari Ekstrak Metanol Daun Kari (Murraya koenigii L.): Hasil Penelitian Tanuhariono, Ardhita Felicia; Limanan, David; Ferdinal, Frans; Yulianti, Eny
Cermin Dunia Kedokteran Vol 52 No 5 (2025): Kardiologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i5.1333

Abstract

Introduction: Curry leaves (Murraya koenigii L.) are plants that naturally grow in the Indian subcontinent, except at the peak of the Himalayan mountains, which in their development have spread widely to various corners of the world. Traditionally, curry leaves have been used by people as medicine. However, it is now known that this plant contains carbazole alkaloid compounds and polyphenols that have antioxidant activity. This is very useful for controlling free radical levels in the human body so that they remain within reasonable limits. This is very useful for controlling the levels of free radicals in the human body to stay within reasonable limits. Free radicals are produced by normal cell metabolism which has recently been associated with the pathophysiology of various diseases. Methods: This in vitro research was to determine phenolic content and antioxidant potential in methanol extract of curry leaves. Total phenolic content testing used the Folin-Ciocalteu method and expressed by Gallic Acid Equivalent (GAE). Total antioxidant capacity testing used the DPPH method and Trolox as a comparison solution. Results: The total antioxidant capacity is expressed in the form of IC50. The total phenolic content of curry leaf methanol extract was 4007.78 μg/mL or equivalent to 133.59 mg GAE/g DW and the total antioxidant capacity of curry leaf methanol extract was 37.418 μg/mL. Conclusion: The total phenolic content of curry leaf methanol extract is high (>5 mg GAE/g). Correspondingly, the total antioxidant capacity of curry leaf methanol extract is also classified as very strong (<150 µg/mL).
Efek Anti-hiperkolesterolemik Ekstrak Etanol Daun Cnidosculus aconitifolius terhadap Pembentukan Lesi Aterosklerosis Arteri Koroner pada Tikus Wistar Jantan yang Diberi Diet Aterogenik (Rattus norvegicus): Hasil Penelitian Saraswati, Ni Ketut Rake Putri; Iswari, Ida Sri; Sumadi, I Wayan Juli
Cermin Dunia Kedokteran Vol 52 No 5 (2025): Kardiologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i5.1336

Abstract

Introduction: Foods high in cholesterol increase the production of free radicals and inflammation, and may also trigger the formation of atherosclerotic lesions. Cnidosculus aconitifolius or tree spinach leaves were known to have antioxidant and anti-inflammatory activities. This study was to determine the effect of Cnidosculus aconitifolius on blood cholesterol level and coronary artery atherosclerotic lesions formation using a rat model. Methods: A randomized post-test-only control group of 30 male Wistar rats (Rattus norvegicus), aged 2-3 months, randomly divided into 3 groups: standard control was given regular food; negative control was given an atherogenic diet; and the treatment group was given an atherogenic diet + Cnidosculus aconitifolius leaf ethanol extracts. The treatment lasted 44 days. Data was analyzed with OneWay ANOVA and Kruskal-Wallis test. Results: The total cholesterol and LDL levels were significantly lower in the treatment group compared to the control group (p<0.001). A decrease of atherosclerotic lesion scores in the treatment group compared to the control (p=0.010) was also observed. Conclusion: Cnidosculus aconitifolius leaf ethanol extracts have an anti-hypercholesterolemic effect, hence the potential to prevent the formation of atherosclerotic lesions in the coronary arteries of hypercholesterolemic Wistar rats.
Gagal Jantung akibat Kardiomiopati Alkoholik pada Pria Muda: Laporan Kasus Darmawan, Rizky
Cermin Dunia Kedokteran Vol 52 No 2 (2025): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i2.1341

Abstract

Background: Alcoholic cardiomyopathy (ACM) is cardiomyopathy caused by consuming large amounts of alcohol. Diagnosis is determined based on alcohol consumption’s history, clinical, and supporting data. Case: Male, 29 years old, came with shortness of breath especially when walking, lying down, and waking-up at night. The patient has been consuming 4 bottles of “Flores wine”/day for the past 14 years. Physical examination showed BP 124/93, pulse 101 x/min, RR 24 x/min, left apex and parasternal area systolic murmur, basal rhonchi, and edema of both feet. Electrocardiography showed RAD, RAE, LBBB, and LVH. Chest x-ray showed cardiomegaly and minimal pleural effusion. Laboratory examination showed SGOT 986.2 U/L, SGPT 448.3 U/L, and electrolyte imbalance. TTE results showed global hypokinetics, all cardiac chambers dilatation, reduced LV systolic function (EF 21.6%), severe TR, and moderate-severe MR. Angiography results showed no stenosis in all coronary arteries. MRI result is similar to TTE without late gadolinium enhancement (LGE). Therapy given according to guided-directed medical therapies (GDMT). Conclusion: ACM is cardiomyopathy with highly variable objective findings. In-depth history regarding alcohol consumption is crucial and other possible causes must be excluded.
Peran Suplementasi Vitamin D dalam Pencegahan Eksaserbasi Asma - Laporan Kasus Berbasis Bukti: Analisis Sagitania, Devina
Cermin Dunia Kedokteran Vol 52 No 1 (2025): Obstetri & Ginekologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i1.1344

Abstract

Background: Asthma is a chronic inflammatory condition affecting the airways, marked by tissue changes and heightened bronchial sensitivity. Vitamin D, as an immunomodulator, may affect the inflammatory responses of the airways. Recent studies suggest that vitamin D supplementation has resulted in fewer exacerbations of asthma and improved lung function in both individuals with asthma and smokers. Other studies revealed a reduction of asthma exacerbations in corticosteroid-treated patients. This study sought to investigate whether vitamin D supplementation can decrease the frequency of asthma exacerbations. Methods: Literature research was done on three databases: PubMed, Cochrane Library, and ScienceDirect, related to the clinical question. Articles were chosen according to specific inclusion and exclusion criteria. All articles were critically appraised using the Oxford Center for Evidence-Based Medicine worksheet. Results: Three meta-analysis articles were critically appraised. The result is vitamin D supplementation can lower the incidence of asthma exacerbation, despite varying doses of vitamin D. Conclusion: Vitamin D supplementation was associated with a decrease in asthma exacerbations, despite varying doses of vitamin D. Vitamin D supplementation to corticosteroids can be considered potentially cost-effective and safe to prevent asthma exacerbations. Future studies should analyze the effect of vitamin D supplementation in long-term asthma therapy using the same dose.
Nefritis Lupus: Klasifikasi dan Tata Laksana Terkini: Tinjauan Pustaka Irianto; Sunjaya, Willy; Koswara, Jonathan
Cermin Dunia Kedokteran Vol 52 No 5 (2025): Kardiologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i5.1346

Abstract

Lupus nephritis (LN) is one of the most common complications in systemic lupus erythematosus. If not detected quickly, LN will often cause reduced kidney function in five years necessitating kidney replacement. Diagnosis and classification of LN are made with a kidney biopsy. The drug of choice is based on the histopathology classification and needs to be tailored case by case. If complete remission is not achieved or if it relapses, the causes need to be investigated. More nephron cells can be saved in earlier therapy to prevent end stage kidney disease complications.
Diagnosis dan Tata Laksana Oftalmia Neonatorum: Tinjauan Pustaka Suki, Ria Marsela
Cermin Dunia Kedokteran Vol 52 No 3 (2025): Oftalmologi dan Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i3.1362

Abstract

Ophthalmia neonatorum or neonatal conjunctivitis is an acute conjunctivitis in newborns under the age of 1 month. The causes are grouped into aseptic and septic types. Diagnosis is made by clinical symptoms and signs as well as laboratory examination. Appropriate treatment based on etiology can prevent permanent eye damage. Without optimal treatment, complications such as corneal ulceration, perforation, and even blindness may occur.
Manfaat Klinis Insulin Glargine U300 - Insulin Basal Generasi Kedua: Analisis Miftah, Nanang
Cermin Dunia Kedokteran Vol 51 No 11 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i11.1363

Abstract

Untreated diabetes can lead to complications and increase the risk of death. Many patients with type 2 diabetes will require injectable medication within 5-10 years after diagnosis, following the failure of two or three oral antidiabetic therapies. Adding basal insulin can be well tolerated, more effective with lower risks of hypoglycemia and weight gain compared to other insulin regimens, but it carries a risk of hypoglycemia. Insulin glargine U300, with its special formulation, reduces the risk of hypoglycemia in diabetic patients.
Kadar Fibrinogen Plasma sebagai Faktor Prognostik Karsinoma Hepatoseluler: Analisis Sidik, Abdul Jafar; Ridayanto, Wandy
Cermin Dunia Kedokteran Vol 52 No 2 (2025): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i2.1367

Abstract

Introduction: This article aims to determine the role of plasma fibrinogen level as a prognostic factor for hepatocellular carcinoma patients. Method: A structured literature review will be conducted through PubMed, Google Scholar, and ScienceDirect, according to the selected clinical questions. Literature selection was based on inclusion and exclusion criteria. The three selected literature were then critically appraised using criteria that included validity, importance, and applicability. Discussion: The three kinds of literature in this article all state that high plasma fibrinogen levels correlate with poor overall survival in hepatocellular carcinoma patients. Conclusion: Plasma fibrinogen levels may act as a prognostic factor for overall survival in hepatocellular carcinoma patients.
Sindrom Down: Skrining, Diagnosis, dan Konsekuensi Kesehatan: Tinjauan Pustaka Zevanya, Evita
Cermin Dunia Kedokteran Vol 52 No 2 (2025): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i2.1368

Abstract

Down syndrome is congenital or genetic abnormality with extra chromosome 21 causing various clinical manifestations and health problem. Down syndrome ranked first as the most common cause of birth defect in Indonesia. Chromosomal abnormality cause Down syndrome children have a higher risk and more common health problems. Down syndrome can burden family or caregiver physically, socially, financially, and emotionally. Proper screening and diagnosis criteria need to be done to establish the diagnosis.
Pengaruh Jumlah Kunjungan, Lama Tinggal (LOS), dan Kepadatan IGD terhadap Mortalitas di IGD RS Tersier Kota Malang: Hasil Penelitian Johan, Willy; Andriani, Rian; Mulyani, Kahar
Cermin Dunia Kedokteran Vol 51 No 11 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i11.1378

Abstract

Introduction: Emergency department (ED) mortality is a critical issue that has a major impact on individuals, society, and the entire health system and is one of the indicators of emergency department service performance. This research aims to provide input to hospital management regarding the impact of non-medical factors (number of visits, length of stay/LOS, and ED crowding) on patient mortality, related to improvement policy-making in ED patient services. Method: A retrospective study on 130 ED shifts from medical record data during 2022-2023. The independent variables were the number of visits, LOS, ED crowding measured by CEDOCS, and ED mortality as the dependent variable. Results: There were deaths in 38 out of 130 shifts in the ED, with a total mortality of 1.6%. Statistical tests showed a significant effect between crowding and ED mortality (p = 0.01), a non-significant effect between visits and ED mortality (p = 0.76), and a non-significant effect between LOS and ED mortality (p = 0.62). The results of the regression analysis were able to explain the data (p = 0.91; Hosmer-Lameshow test). The area under the curve (AUC) for prognosis in hospital treatment is 0.641 with a 95% confidence interval of 0.539-0.744 (medium category). Conclusion: The significant effect between crowding and patient mortality in the ED indicates that strategic management must be carried out to reduce ED crowding.

Page 123 of 132 | Total Record : 1312

 121   122   123   124   125 

Filter by Year

2018 2026


Reset
Filter By Issues
All Issue Vol 53 No 03 (2026): Penyakit Dalam Vol 53 No 02 (2026): Kedokteran Umum Vol 53 No 01 (2026): Kedokteran Umum Vol 52 No 12 (2025): Kedokteran Umum Vol 52 No 11 (2025): Penyakit Dalam Vol 52 No 10 (2025): Kedokteran Umum Vol 52 No 9 (2025): Pediatri Vol 52 No 8 (2025): Penyakit Dalam Vol 52 No 7 (2025): Kedokteran Umum Vol 52 No 6 (2025): Kesehatan Jiwa Vol 52 No 5 (2025): Kardiologi Vol 52 No 4 (2025): Kedokteran Umum Vol 52 No 3 (2025): Oftalmologi dan Dermatologi Vol 52 No 2 (2025): Pediatri Vol 52 No 1 (2025): Obstetri & Ginekologi Vol 51 No 12 (2024): Kedokteran Umum Vol 51 No 11 (2024): Kedokteran Umum Vol 51 No 10 (2024): Infeksi Vol 51 No 9 (2024): Kedokteran Umum Vol 51 No 8 (2024): Penyakit Dalam Vol 51 No 7 (2024): Kedokteran Umum Vol 51 No 6 (2024): Cardiology Vol 51 No 5 (2024): Kedokteran Umum Vol 51 No 4 (2024): Oftalmologi Vol 51 No 3 (2024): Neurologi Vol 51 No 2 (2024): Dermatologi Vol 51 No 1 (2024): Kedokteran Umum Vol 50 No 12 (2023): Penyakit Dalam Vol 50 No 11 (2023): Pediatri Vol 50 No 10 (2023): Kedokteran Umum Vol 50 No 9 (2023): Penyakit Dalam Vol 50 No 8 (2023): Dermatiologi Vol 50 No 7 (2023): Kardiovaskular Vol 50 No 6 (2023): Edisi CME Vol 50 No 5 (2023): Kedokteran Umum Vol 50 No 4 (2023): Anak Vol 50 No 3 (2023): Kardiologi Vol 50 No 2 (2023): Penyakit Dalam Vol 50 No 1 (2023): Oftalmologi Vol 49 No 12 (2022): Dermatologi Vol 49 No 11 (2022): Neurologi Vol 49 No 10 (2022): Oftalmologi Vol 49 No 9 (2022): Neurologi Vol 49 No 8 (2022): Dermatologi Vol 49 No 7 (2022): Nutrisi - Vitamin D Vol 49 No 6 (2022): Nutrisi Vol 49 No 5 (2022): Neuro-Kardiovaskular Vol 49 No 4 (2022): Penyakit Dalam Vol 49 No 3 (2022): Neurologi Vol 49 No 2 (2022): Infeksi Vol 49 No 1 (2022): Bedah Vol 48 No 11 (2021): Penyakit Dalam - COVID-19 Vol 48 No 1 (2021): Infeksi COVID-19 Vol 48 No 10 (2021): Continuing Medical Education - Edisi 4 Vol 48 No 8 (2021): Continuing Medical Education - Edisi 3 Vol 48 No 5 (2021): Continuing Medical Education - Edisi 2 Vol 48 No 2 (2021): Continuing Medical Education - Edisi 1 Vol 48 No 12 (2021): Penyakit Dalam Vol 48 No 9 (2021): Neurologi Vol 48 No 7 (2021): Infeksi Vol 48 No 6 (2021): Kardiologi Vol 48 No 4 (2021): Dermatologi Vol 48 No 3 (2021): Obstetri - Ginekologi Vol 47 No 10 (2020): Dermatologi Vol 47 No 9 (2020): Infeksi Vol 47 No 8 (2020): Oftalmologi Vol 47 No 7 (2020): Neurologi Vol 47 No 6 (2020): Kardiologi & Pediatri Vol 47 No 5 (2020): Bedah Vol 47 No 4 (2020): Interna Vol 47 No 3 (2020): Dermatologi Vol 47 No 2 (2020): Infeksi Vol 47 No 1 (2020): Bedah Vol 46 No 7 (2019): Continuing Medical Education - 2 Vol 46 No 12 (2019): Kardiovakular Vol 46 No 11 (2019): Pediatri Vol 46 No 10 (2019): Farmakologi - Continuing Professional Development Vol 46 No 9 (2019): Neurologi Vol 46 No 8 (2019): Pediatri Vol 46 No 6 (2019): Endokrinologi Vol 46 No 5 (2019): Pediatri Vol 46 No 4 (2019): Dermatologi Vol 46 No 3 (2019): Nutrisi Vol 46 No 2 (2019): Interna Vol 46 No 1 (2019): Obstetri-Ginekologi Vol 45 No 12 (2018): Interna Vol 45 No 11 (2018): Neurologi Vol 45 No 10 (2018): Muskuloskeletal Vol 45 No 9 (2018): Infeksi Vol 45 No 8 (2018): Dermatologi Vol 45 No 7 (2018): Onkologi Vol 45 No 6 (2018): Interna Vol 45 No 5 (2018): Nutrisi Vol 45 No 4 (2018): Neurologi Vol 45 No 3 (2018): Muskuloskeletal Vol 45 No 2 (2018): Urologi Vol 45 No 1 (2018): Dermatologi More Issue