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Contact Name
Dita Arccinirmala
Contact Email
dorotea.arccinirmala@kalbe.co.id
Phone
+6281905203065
Journal Mail Official
CDK@kalbe.co.id
Editorial Address
Redaksi CDK Gedung Kalbe, gedung 2 lantai 2 Jl. Letjen Suprapto Kav. 4. Cempaka Putih - Jakarta 10510
Location
Unknown,
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INDONESIA
Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Articles 1,276 Documents
Penanganan Lesi pada Ramp Lesi Meniskus Umum: Perbaikan atau Pengobatan Konservatif: Tinjauan Pustaka Davidson, Alhoi Lesley; Giarso, Peter
Cermin Dunia Kedokteran Vol 52 No 12 (2025): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i12.1644

Abstract

Ramp lesions are the most frequent intra-articular injuries associated with anterior cruciate ligament (ACL) ruptures and are often missed during diagnosis. They occur at the meniscocapsular junction of the posterior horn of the medial meniscus and may compromise knee stability. Magnetic resonance imaging (MRI) can identify ramp lesions but has limited sensitivity; therefore, arthroscopy remains the diagnostic gold standard. Treatment options include conservative management for stable tears and surgical repair for unstable or type IV–V lesions. Recent studies show no significant difference in long-term knee stability between repaired and unrepaired lesions; however, repaired lesions demonstrate faster functional recovery. Repair is particularly advised for patients in their productive years, especially athletes or individuals with high physical-activity demands requiring optimal knee stability. Appropriate radiologic evaluation combined with structured postoperative rehabilitation improves clinical outcomes and reduces recurrence. This review summarizes current evidence on the epidemiology, diagnosis, classification, and management strategies for ramp lesions commonly found in association with ACL-related meniscal injuries.
Penyintas Bayi Prematur Berat Badan Lahir Amat Sangat Rendah (BBLASR) di RSUD Tipe C: Laporan Kasus: Laporan Kasus Putri, Dessy Natasha Ade; Naur, Oktaviani Mulianiarti
Cermin Dunia Kedokteran Vol 52 No 12 (2025): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i12.1687

Abstract

Introduction: Low birth weight is defined by the World Health Organization as a birth weight of less than 2,500 grams, while extremely low birth weight is defined as a birth weight of less than 1,000 grams. Babies with low birth weight are 20 times more likely to experience complications and death compared to babies with normal birth weight. Case: A female infant, gestational age 28–29 weeks, birth weight 800 g, born spontaneously to a G3P1A1 mother with a history of premature rupture of membrane < 18 hours, urinary tract infection, and threatened preterm delivery. The infant cried immediately after birth, AS 7/9, and at 10 minutes appeared to be short of breath with a threat of respiratory distress. CPAP was administered, thermoregulation was performed, and intravenous antibiotics were given. Parenteral nutrition was given starting at 80 mL/kgBW/day and increased gradually. Breast milk was given on the second day starting at 20 mL/kgBW/day every 3 hours via OGT, increased by 10–20 mL/day according to tolerance. Complications during treatment included recurrent temperature instability, brown-colored vomit, and abdominal distension. The infant’s weight dropped to 700 g, and anemia (Hb = 10.6) developed. At 30 days of age, Kangaroo mother care, oral care, and physiotherapy were provided and taught to the parents. At 12 months of corrected age, the infant weighed 7.8 kg and was developing according to age milestones. Discussion: Early feeding plays a crucial role in the care of premature infants because it supports growth and gastrointestinal maturation. Enteral nutrition is better than total parenteral nutrition because it helps prevent problems from IV use, infections, side effects of total parenteral nutrition, and not eating. Conclusion: Prematurity is the leading cause of morbidity and mortality in neonates and children under 5 years of age. Proper management and good nutrition will support optimal growth, improve neurological outcomes, and reduce the incidence of sepsis and the possibility of retinopathy.
Penentuan Kuantitas Kehilangan Darah pada Kasus Perdarahan Obstetri: Tinjauan Pustaka Winata, I Gde Sastra; ., Leonardo; Candijaya, Gita Sirini; Muliawan, Erlin Purnama; Pratama, I Gede Bayu Adi; Pramana, Bagus Andika
Cermin Dunia Kedokteran Vol 52 No 12 (2025): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i12.1692

Abstract

Postpartum hemorrhage is a leading cause of maternal death worldwide and remains a serious health concern, particularly in developing countries such as Indonesia. Accurate estimation of blood loss is essential for early detection of emergencies and for implementing rapid and appropriate interventions for patients. This review discusses several methods used to determine the amountof blood loss in obstetric cases, including visual estimation, quantitative measurement, and laboratory evaluation. The visual method is easily applied in primary health facilities but frequently underestimates blood loss due to lighting, fluid mixtures, and the experience of health providers. Quantitative methods, such as weighing blood-soaked materials or collecting blood in calibrated containers, are considered more objective and accurate. Laboratory assessment through hemoglobin concentration, hematocrit levels, and spectrophotometric analysis provides confirmation of clinical estimates. Combining quantitative and laboratory approaches can improve diagnostic accuracy, expedite clinical management, and ultimately reduce maternal morbidity and mortality associated with obstetric hemorrhage.
Lama Rawat Kurang dari Empat Jam di Instalasi Gawat Darurat sebagai Indikator Mutu Pelayanan dan Penerapannya di Indonesia: Tinjauan Pustaka Sulistio, Septo; Gani, Ascobat
Cermin Dunia Kedokteran Vol 52 No 12 (2025): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i12.1917

Abstract

The emergency department (ED) operates 24 hours in a day, 7 days, in a a week, to provide emergency medical care, but with the growing number of visits, delays in patient assessment and treatment can impact care quality. A common performance indicator used to measure ED efficiency is the length of stay (LOS) of less than four hours, reflecting both service quality and patient flow management. This target has been widely implemented in a few countries, such as the United Kingdom and Australia to enhance ED operations. In Indonesia, a similar target has been set for national referral hospitals, aiming for 90% compliance. However, initial evaluations show that only a small fraction of hospitals meet this target, raising concerns about its feasibility. Despite these challenges, the four-hour LOS remains a relevant quality indicator in EDs. Achieving this goal requires collaborative efforts from allhealthcare stakeholders to improve ED efficiency and patient care. This literature review explores the feasibility and challenges of this target in all parts of Indonesia.
Efektivitas Efepoetin Alfa dalam Mengatasi Anemia yang Disebabkan oleh Kemoterapi pada Pasien Kanker Payudara: Serangkaian Kasus: Laporan Kasus Abidin, Zainal; Fatimah, Anova
Cermin Dunia Kedokteran Vol 52 No 12 (2025): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i12.1973

Abstract

Introduction: Anemia is a common complication among cancer patients and substantially reduces quality of life (QOL) through symptoms such as fatigue and cognitive impairment. This case evaluates the use of efepoetin alfa to treat chemotherapy‑induced anemia (CIA) in late‑stage breast cancer patients in Indonesia. Case: Six Asian women aged 43–59 years with stage III breast cancer receiving docetaxel‑doxorubicin chemotherapy developed moderate anemia (mean baseline hemoglobin [Hb] 9.5 g/dL). Patients received subcutaneous efepoetin alfa (generally 0.3 mg/0.3 mL once); Hb was reassessed at an average of 8 days after the last injection. Discussion: Post‑treatment mean Hb rose to 12.1 g/dL (mean ΔHb ≈ 2.6 g/dL). No serious adverse events were observed during the short follow‑up. Conclusion: In this case, efepoetin alfa was associated with rapid increases in Hb and improved patient‑reported outcomes; however, a confirmatory larger study, standardized dosing and monitoring, and longer follow‑up are required to define efficacy and long‑term safety.
Potensi Ekstrak Akar Manis (Glycyrrhiza glabra L.) untuk Pengobatan Hiperpigmentasi: Tinjauan Pustaka Sianturi, Ester Yulyana; Primayanti, I Dewa Ayu Inten Dwi
Cermin Dunia Kedokteran Vol 52 No 12 (2025): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i12.2043

Abstract

Hyperpigmentation is a dermatological condition characterized by increased melanin production which is the pigment responsible for skin color. Melanin is synthesized by melanocytes through an enzymatic pathway regulated by the enzyme tyrosinase. This process can be triggered by various factors such as ultraviolet (UV) radiation, hormonal changes, skin inflammation, aging, and the use of certain medications. One therapeutic approach is the use of natural ingredients, including herbal plant extracts. Glycyrrhiza glabra L., commonly known as licorice root, has long been used in both traditional and modern medicine due to its active compounds such as glabridin, which possesses antioxidant and tyrosinase-inhibiting properties. This review aims to evaluate the potential of licorice root extract as a natural depigmenting agent in the treatment of hyperpigmentation. A literature review was conductedusing databases PubMed, Google Scholar, NCBI, and ResearchGate. The findings indicate that glabridin selectively inhibits tyrosinase activity without causing skin irritation and also exhibits anti-inflammatory and photoprotective effects. Licorice root extract showspromise as a safe and effective natural therapeutic option for managing hyperpigmentation.

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