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INDONESIA
Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Health Professions
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 1,288 Documents
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Analisis Bibliometrik Pemanfaatan Layanan Telemedicine dalam Bidang Obstetri dan Ginekologi: Meta-Analisis Fatma, Widi; Mahardika Herlambang, Penggalih; Budiyanti, Rani Tiyas
Cermin Dunia Kedokteran Vol 53 No 01 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i01.1735

Abstract

Introduction: Telemedicine in health services has various advantages, such as cost flexibility and time efficiency. This research aims to map research related to the application of telemedicine in obstetrics and gynecology. Methods: This study is a quantitative, descriptiveanalytical research using bibliometric analysis of articles published in the Scopus database from 2014 to 2024. Results: We obtained 36 articles on the application of telemedicine in obstetrics and gynecology, with a fluctuating number each year. The country with the most affiliated researchers was the United States, with 19 publications. Most articles were research articles (80.6%) and published in medical journals (67.3%). Conclusion: Based on the study’s results, 4 countries have conducted collaborative research, and 3 keyword mapping clusters relate to the application of telemedicine in obstetrics and gynecology. Cross-sector and cross-border collaboration is necessary, especially in ethical and legal aspects that enable the implementation of cross-border or cross-continental telemedicine. Further research and literature review are needed to assess further the procedures, benefits, and barriers to implementing telemedicine services in obstetrics and gynecology.
Dampak Rokok terhadap Ekspresi Matrix Metalloproteinase-9 (MMP-9) dan Hubungannya dengan Penyakit Paru Obstruktif Kronik: Tinjauan Sistematik Nugraha Putra, Oki; Anabella, Rantie Queenza; In’ami, Istiara Nafida; Nur Hasibullah Ma, Akbar Yuniar; Purwanto, Ryo Wahyu
Cermin Dunia Kedokteran Vol 53 No 01 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i01.1788

Abstract

Introduction: Cigarette smoke can induce the expression of matrix metalloproteinase-9 (MMP-9) and is associated with COPD. This review aims to assess the impact of cigarette smoke on MMP-9 expression and its association with COPD. Methods: This study is a scoping review using articles analyzing the impact of cigarette smoke on MMP-9 levels in COPD patients from the PubMed and Google Scholar databases. A total of 11 articles that met the inclusion criteria were used in this review, of which 6 studies used serum or plasma, 1 study used bronchoalveolar lavage (BAL), and 4 studies used sputum samples to measure MMP-9 levels. Results: Overall, MMP-9 levels were found to be significantly greater in COPD patients who smoked compared to non-smoking COPD patients and healthy individuals. MMP-9 levels increased with increasing severity of COPD. MMP-9 levels correlated with the smoking index. Conclusion: More cigarette consumption will further increase MMP-9 levels. Smoking increases MMP-9 expression and is associated with COPD.
Gagal Napas Akut Tipe II pada Pasien Penyakit Paru Obstruktif Kronik (PPOK) Eksaserbasi Akut yang Diterapi dengan High Flow Nasal Cannula (HFNC): Laporan Kasus: Laporan Kasus Rahardjo, Abdi Malik; Mukhlis, Mokhammad
Cermin Dunia Kedokteran Vol 53 No 01 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i01.1805

Abstract

Introduction: Acute respiratory failure is a condition seen in respiratory system failure to supply gas exchange, oxygenation, and elimination of carbon dioxide (CO2) processes that occurs in minutes or hours. Case: A 57-year-old male came to the emergency room with complaints of shortness of breath since 5 days ago, worsened during light activities. The patient also complained of worsening cough since 5 days ago, accompanied by thick yellowish-white phlegm. History of smoking 12 sticks/day since the age of 20 years and quit 5 years ago. Diagnosis was acute respiratory failure type II and the cause was chronic obstructive pulmonary disease (COPD) acute exacerbation. The management is high flow nasal cannula (HFNC) with FiO2 80%, because HFNC has an additional heating and humidification system that makes it more comfortable. Discussion: Alveolar hypoventilation and increased minute ventilation in COPD patients may carry a type II acute respiratory failure risk. Conclusion: Type II acute respiratory failure commonly occurs in patients with chronic respiratory diseases such as COPD. High flow nasal cannula (HFNC) oxygen therapy may be the best option.
Ketidakseimbangan Elektrolit yang Menyebabkan Fenotipe Brugada: Perpotongan Kompleks antara Hiperkalemia, Hiponatremia, dan Asidosis – Laporan Kasus: Laporan Kasus Imowanto, Yuddy; Abdullah, Taufiq; Wahyuni, Sri
Cermin Dunia Kedokteran Vol 53 No 01 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i01.1809

Abstract

Introduction: Brugada phenocopies (BrP), which are different from real congenital Brugada syndrome (BrS), are clinical entities with different etiology. BrP can manifest in a range of conditions, such as metabolic disturbances like hypokalemia, hyperkalemia, hypophosphatemia, hyponatremia, and acute toxicity. Case: Brugada phenocopy was observed in the ECG of a 68-year-old male, resolved following the correction of hyperkalemia, hyponatremia, and acidosis. The patient presented with septic shock and multiorgan dysfunction, which contributed to severe electrolyte imbalance and metabolic derangements. Despite initial stabilization and improvement in ECG findings after targeted correction, the patient ultimately developed progressive clinical deterioration. Discussion: Recognizing BrP helps identify reversible causes of the ECG changes, allowing for proper treatment and prevention of complications. This case highlights the importance of evaluating underlying metabolic and systemic conditions when encountering Brugada-like ECG patterns. Conclusion: Brugada phenocopy can occur in hyperkalemia and hyponatremia in an acidosis state. Clinicians should consider comprehensive clinical assessment, laboratory evaluation, and ECG monitoring to distinguish BrP from congenital BrS, especially in critically ill patients.
Sindrom Stevens-Johnson yang Disebabkan oleh Carbamazepine pada Pasien Epilepsi: Laporan Kasus: Laporan Kasus Harlim, Charity; Kelvin, Kelvin; Hartati, Agung Triana
Cermin Dunia Kedokteran Vol 53 No 01 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i01.1811

Abstract

Introduction: As a first-line antiepileptic drug for partial and tonic-clonic seizures, carbamazepine requires long-term use. This drug carries a risk of Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) reaction. Case: A 23-year-old woman with a history of seizures had reddish rashes on the face, neck, chest, back, and left and right upper extremities covering 10% of the body surface area (BSA) after taking carbamazepine 200 mg twice a day for her seizures. Discussion: The patient was given methylprednisolone 16 mg tablets twicea day, IV diphenhydramine twice a day, and other symptomatic drugs. After 9 days, the patient was discharged with phenytoin 100 mg tablets twice a day as a substitute for carbamazepine. Early treatment with high-dose systemic steroids provides benefits of rapid recovery,especially in SJS patients where skin damage is not too extensive and can be restored by the anti-inflammatory effects of steroids. The main treatment of SJS/TEN is early recognition and immediate discontinuation of the drug. Conclusion: Carbamazepine is often a risk factor forSJS, thus an alternative treatment is needed.
Seorang Wanita Berusia 27 Tahun dengan Tuberkulosis Genitourinari: Masalah Diagnosis di Daerah Pedesaan Indonesia - Laporan Kasus: Laporan Kasus Asali, Teresa; Setiady, Feddy; Putra, Agung Ambara; Salim, Harina
Cermin Dunia Kedokteran Vol 53 No 01 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i01.1883

Abstract

Introduction: Genitourinary tuberculosis (TB) is one of the most common forms of extrapulmonary TB, yet it is often misdiagnosed due to its nonspecific symptoms and very often mimic recurrent urinary tract infections. Case: A 27-year-old woman was referred to the hospital with complaints of frequent and painful urination for the past six months, along with intermittent fever and occasional cough.She had received multiple courses of antibiotics, but her symptoms did not resolve. Laboratory investigations, including urine microscopy, LAM antigen, and Xpert MTB/RIF, revealed Mycobacterium tuberculosis in the urine sample. A chest x-ray and sputum acid fast bacilli (AFB) examination indicated pulmonary tuberculosis. The patient was treated with standard anti-tuberculosis drugs for 6 months, resulting in clinical improvement. Discussion: Diagnosing genitourinary TB is challenging due to its nonspecific presentation and the limited sensitivity of routine urine microscopy. While Xpert MTB/RIF offers higher accuracy, its availability is restricted in many settings. LAM testing shows usefulness in HIV-associated TB, but its role in non-HIV genitourinary TB is still uncertain. Improved, accessible diagnostic strategies are needed for earlier detection. Conclusion: Genitourinary TB remains challenging to diagnose, particularly in rural areas with limited access to advanced diagnostics. A careful medical history, repeat urinalysis, and simple tests such as urine smear microscopy, LAM, and MTB/RIF can aid early detection. Early diagnosis is essential to prevent complications such as end-stage kidney failure.
Aktivitas Fisik Rutin sebagai Anti-Aging dan Pencegahan Sarkopenia pada Wanita: Tinjauan Pustaka Dewi, Ade Yasinta; Ayu Dewi, Ni Nyoman
Cermin Dunia Kedokteran Vol 53 No 01 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i01.1982

Abstract

Aging is a natural process of declining body functions, including a decrease in muscle mass and strength known as sarcopenia. Sarcopenia has a higher prevalence in menopausal women due to the decline in estrogen levels. This condition affects quality of life, fall risk, and independence. This literature review explores the role of regular physical activity as an anti-aging intervention and prevention of sarcopenia in women. A literature search was conducted in the Google Scholar, PubMed, ScienceDirect, and DOAJ databases for relevant articles (originalresearch or reviews) published between 2024 and 2025. Data analysis used a narrative synthesis approach on 30 selected articles. Results showed that consistently performed physical activity, especially resistance training (moderate–high intensity), multimodal training, andtraining with blood flow restriction, is highly effective in improving muscle mass, strength, and physical function. Combination of physical activity with adequate protein intake (≥ 1.0 g/kgBB/day) showed significant synergistic effects, especially in women with sarcopenic obesity.Technology-based interventions potentially improve program adherence. It is concluded that regular physical activity, particularly resistance training supported by optimal nutrition, is an effective non-pharmacological strategy to slow the aging process and prevent sarcopenia.
Pemberian Bubur Tempe Instan dan Sediaan Komersial Diabetes pada Pasien Diabetes Melitus Tipe 2, Kanker Kaput Pankreas, dan Hipoalbuminemia: Studi Kasus: Laporan Kasus Devi, Ni Putu Destriani; Herawati, Ni Putu Elsa
Cermin Dunia Kedokteran Vol 53 No 01 (2026): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i01.2068

Abstract

Introduction: Patients with diabetes mellitus and caput pancreas cancer generally experience decreased food intake due to gastrointestinal complaints, such as abdominal pain, nausea, vomiting, and feeling full. This condition can be managed by providing small portions of nutrientdense and easily digested food to prevent decline in nutritional status and patient condition. Case: A 58-year-old male with right upper abdominal pain, fever, and white stools was treated for caput pancreas cancer and hypoalbuminemia. History of type 2 diabetes mellitus for 2years and biliary stent placement. Food intake at home is < 25% of the requirement. The patient is underweight with body mass index (BMI) 16 kg/m2, hypoalbuminemia (2.6 g/dL), and hyperglycemia (random glucose 220 mg/dL). This nutritional intervention aims to gradually optimizefood intake (target > 80% requirement) in 5 days, with easily digestible and low glycemic index food in the form of modification of instant tempeh porridge and commercial diabetic preparation in small portion. Discussion: The nutritional intervention is acceptable to the patient.Conclusion: Modified instant tempeh porridge and commercial diabetic preparation can increase patient intake with good acceptance and improve gastrointestinal tolerance.

Page 129 of 129 | Total Record : 1288

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