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INDONESIA
ASPIRATOR - Journal of Vector-Borne Diseases Studies
Published by Perkumpulan Entomologi Kesehatan Indonesia
ISSN : -     EISSN : -     DOI : -
Core Subject : Health, Science, Social,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Social Sciences
Arjuna Subject : Ilmu Lingkungan (semua ketegori) - Kesehatan, Toksikologi dan Mutasi Gen
Articles 43 Documents
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Imunogenisitas, Keamanan, dan Efikasi Vaksin Malaria: Tinjauan Sistematis dan Network Meta-Analysis dari Uji Klinis Acak Terkontrol: Immunogenicity, safety, and efficacy of malarial vaccines: a systematic review and network meta-analysis of randomized controlled trials Kusiyanto Taslim, Fitranda; Hermansyah, Bagus; Agustina, Dini; Yuli Rahmantia, Vania
Aspirator Vol 16 No 1 (2025): Jurnal Aspirator Volume 16 Nomor 1 2025
Publisher : Perkumpulan Entomologi Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58623/aspirator.v16i1.114

Abstract

Malaria remains a major global health issue, with challenges in existing control methods like insecticide resistance and artemisinin-based therapy failures. Vaccines offer a promising solution to reduce transmission, build herd immunity, and decrease morbidity and mortality, especially in vulnerable populations. This study conducts a network meta-analysis of malaria vaccines to compare their immunogenicity, safety, and efficacy. A systematic review following PRISMA-NMA guidelines was performed using four databases—PubMed, Cochrane Library, ScienceDirect, and Google Scholar—assessing study quality with the Cochrane Risk of Bias 2.0 tool. The analysis, which included over 33,000 participants from 57 clinical trials, revealed that RTS,S/AS01 and RTS,S/AS02 significantly increased antibody titers despite heterogeneity. Safety outcomes showed RTS,S/AS02 and FMP1/AS02 were linked to increased injection site pain, and RTS,S vaccines had a higher risk of fever. R21/Matrix-M showed the highest efficacy in preventing clinical malaria episodes, though data on it were limited. Vaccines like PfSPZ and PvCS had fewer side effects but weaker antibody responses. Overall, RTS,S vaccines were highly immunogenic and effective, though safety profiles varied, and the limited data on certain vaccines like R21/Matrix-M underscored the need for further research to validate their long-term effects. 
Indeks Entomologi dan Faktor Jenis Rumah yang Berkaitan dengan Keberadaan Telur Aedes spp. di Kelurahan Sungai Pinang, Provinsi Jambi: Entomological Index and House Type Factors Related to the Existence of Aedes spp. Eggs in Sungai Pinang Urban Village, Jambi Province Unida, Tazkiah; Satoto, Tri Baskoro Tunggul; Garjito, Triwibowo Ambar; Martono, Edhi
Aspirator Vol 16 No 1 (2025): Jurnal Aspirator Volume 16 Nomor 1 2025
Publisher : Perkumpulan Entomologi Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58623/aspirator.v16i1.117

Abstract

Kelurahan Sungai Pinang memiliki kepadatan penduduk tinggi dan endemis dengue. Keberadaan Aedes spp. sebagai vektor virus dengue diperparah dengan kondisi lingkungan yang kurang terkontrol, seperti banjir yang memperbanyak wadah tergenang sebagai tempat perindukan nyamuk. Variasi tipe rumah juga mempengaruhi populasi Aedes spp., sehingga penelitian mengenai indeks entomologi dan jenis rumah yang mempengaruhi keberadaan telur Aedes spp. perlu dilakukan. Penelitian ini bertujuan untuk mengamati indeks entomologi Aedes spp. di Kelurahan Sungai Pinang (1°59'13.3" S dan 102°02'55.2" E) berupa house index (HI), container index (CI), breteau index (BI), ovitrap index (OI), dan angka bebas jentik (ABJ) di wilayah RT 07 dan RT 18 beserta kaitannya dengan jenis rumah sampling di lokasi penelitian. Penelitian ini menggunakan metode observasional dengan desain cross-sectional. Teknik sampling secara purposive dengan memilih RT dengan kasus dengue tahun 2023 – awal tahun 2024. Data indeks entomologi dianalisis secara univariat, sedangkan analisis korelasi Spearman dilakukan secara bivariat. Hasil penelitian menunjukkan HI sebesar 22,35%, CI 15,22%, dan BI 63,92%. Nilai HI dan CI termasuk dalam kategori densitas sedang, sedangkan BI termasuk kategori tinggi. Angka bebas jentik di RT 07 dan RT 18 adalah 77,65%, masih di bawah target nasional 95%. Ovitrap index mencapai 89,41%, menunjukkan tingkat resiko tinggi. Rumah yang ditemukan telur nyamuk > 10 buah adalah rumah semi-permanen dengan celah di dinding kayu dan atap tanpa plafon. Kelurahan Sungai Pinang masuk dalam kategori berisiko tinggi terjadi penularan dengue.
Keong Sulawesidrobia sp Kandidat Kompetitor Inang Perantara Schistosoma japonicum Di Dataran Tinggi Bada Kabupaten Poso: Sulawesidrobia sp Snails as Competitor Candidates for Intermediate Hosts of Schistosoma japonicum in the Bada Highlands of Poso Regency widjaja, Junus; Satrija, Fadjar; Ridwan, Yusuf; Garjito, Triwibowo Ambar
Aspirator Vol 16 No 1 (2025): Jurnal Aspirator Volume 16 Nomor 1 2025
Publisher : Perkumpulan Entomologi Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58623/aspirator.v16i1.120

Abstract

Schistosomiasis, a disease caused by the trematode worm Schistosoma japonicum, with the intermediate host snail Oncomelania hupensis lindoensis, is a complex issue that requires ongoing investigation. The Bada highlands of Poso Regency, one of Indonesia's endemic areas, was found to be an endemic area for schistosomiasis in 2008 due to the presence of cases in humans and the intermediate host snail O. h. lindoensis. This article discusses the Sulawesidrobia sp snail, a significant finding in the Bada endemic area.  Surveys were conducted on the same O. h. lindoensis snail habitat in 2017 and 2019, using the man per minute and crushing methods. In 2019, the Sulawesidrobia sp snail habitat was more dominant, with as many as 22 habitats, and the type of habitat was the same as the type of O. h lindoensis habitat. This led to a decrease in the habitat of O. h lindoensis. Sulawesidrobia sp snails, with their small shells, slightly convex circles, and two red lines, were found to inhabit water channels in gardens, rice fields, and ponds, highlighting the need for further research in this area.

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