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Jurnal Kedokteran Brawijaya
Published by Universitas Brawijaya
ISSN : 02169347     EISSN : 23380772     DOI : http://dx.doi.org/10.21776/ub.jkb
Core Subject : Health,
Medicine & Pharmacology
JKB contains articles from research that focus on basic medicine, clinical medicine, epidemiology, and preventive medicine (social medicine).
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 822 Documents
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Nonsense Mutation (c.1425G>A-p.Trp475Ter) Associated with Oculocutaneous Albinism Type 1A (OCA1A) in Yogyakarta Karmilah, Karmilah; Dian Pratiwi, Arini; Nur Handayani, Niken Satuti
Jurnal Kedokteran Brawijaya Vol. 33 No. 4 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2025.033.04.8

Abstract

Oculocutaneous Albinism (OCA) is a disorder characterized by impaired melanin synthesis that leads to hypopigmentation of the skin, hair, and eyes, accompanied by distinct ocular abnormalities. The global prevalence of all forms of albinism is approximately 1 in 17,000 individuals, and OCA1 is the most common type. OCA1 results from mutations in the TYR gene and specifically involves a complete loss of tyrosinase enzyme function, resulting in a total absence of pigment in the skin, eyes, and hair. This case report describes two male patients with congenital symptoms of extremely light or depigmented skin and hair. Both presented with white eyelashes and eyebrows, grayish irises, and ocular abnormalities, including nystagmus, photophobia, and strabismus. The analysis showed a genetic variant in the exon of the TYR gene with the mutation variant c.1425G>A/p.Trp475Ter and was found to be a nonsense mutation.
Identification of ACE2 and TMPRSS2 Gene Polymorphisms in Covid-19 Survivors with Hypertension and Diabetes Mellitus using the rhAmp PCR Method Setijowati, Eva Diah; Suprapti, Herni; Waskito, Budi Arief; Wulandari, Retno Dwi
Jurnal Kedokteran Brawijaya Vol. 33 No. 4 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2025.033.04.1

Abstract

The Covid-19 pandemic has caused significant global mortality and morbidity. Covid -19 infection is caused by the SARS-CoV-2 virus, which requires a receptor on the host cell to enter, primarily Angiotensin-Converting Enzyme 2, encoded by the ACE2 gene, and Transmembrane Serine Protease 2, encoded by the TMPRSS2 gene. Several factors can influence Covid-19 mortality and morbidity, including gender, comorbidities such as diabetes mellitus (DM), obesity, cardiovascular diseases, and genetic factors. ACE2 and TMPRSS2 polymorphisms are believed to worsen the condition of Covid-19 patients. This study aimed to identify polymorphisms in the ACE2 (rs2285666 G>C) and TMPRSS2 (rs2070788 A>G) in  Covid-19 survivors with hypertension and diabetes mellitus. The total sample was 30 hypertension and diabetes mellitus   patients treated at Islamic Hospital Surabaya. A total of 3 ml of blood was drawn from the median cubital vein and placed into an EDTA vacutainer. DNA extraction was performed using the High Pure PCR Template Preparation Kit (Roche). Identification of ACE2 and TMPRSS2 polymorphisms was performed using the rhAmp SNP genotyping method with the LightCycler® system (Roche 480II). Genotyping results for ACE2 showed that 55.2% of patients had the GG (wild-type) with a G allele frequency of 68.9%. Genotyping for the TMPRSS2 showed that 60% of patients had the GG (mutant-type) with a G allele frequency of 78.3%. During Covid-19 infection, neither GG genotype (ACE2) and the GG genotype (TMPRSS2) exhibited severe symptoms.
Non-compliance of Hospital X Employee in Implementing Standard Operational Procedures of Instrument Decontamination and Chest X-Ray Services Prahadiani, Saesar Revita; Kuncoro, Wahyudi; Hariyanti, Tita; Zuhriyah, Lilik; Sarwiyata, Tri Wahyu; Pradina, Fifin
Jurnal Kedokteran Brawijaya Vol. 33 Supplement 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.01.6s

Abstract

Good hospital management is important to maintain the safety of patients, staff and hospital visitors. Each hospital employee responsible for patient safety by carrying out work according Standard Operating Procedure (SOP) guidelines agreed by organization. This study aims to identify the casues factors and the solution for hospital employees to not comply with the SOP. This study uses a qualitative descriptive approach. Methods of data collection by conducting direct observation and interviews. Subjects in the study were determined based on purposive sampling, as many as 8 respondents consisting of the inpatient room's head, nurses and radiology officers. It is important to apply a system approach in the management of an organization. The elements included in the systems approach are planning, organizing, actuating and controlling. From those elements, there are things that not properly carried in the hospital. The existing procedures were not followed by the employees, for example, procedures regarding instrument decontamination in the inpatient room and photo reading at the radiology service. Non-compliance with this procedure is influenced by several factors, namely the staff lack of discipline and responsibility, inappropriate procedures, facilities that are not available, and there is no socialization of the procedure to hospital employees. The non-compliance of employees at X hospital was caused by procedural factors, decontamination and radiology officer's performance factors and hospital's facilities. For this reason, it is necessary to conduct periodic outreach, monitoring and evaluation of the SOP and hospital employees to improve the quality of hospital services and customer satisfaction.
Paramedic Mental Workload in Pandemic Covid-19 Era Arifianto, Dedy; Fitriasari, Nikma; Mastuti, Ni Luh Putu Herli
Jurnal Kedokteran Brawijaya Vol. 33 Supplement 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.01.1s

Abstract

The number of Covid-19 patients hospitalized continues to increase in line with the increase in Covid-19 cases in Indonesia. The increasing number of Covid-19 patients in hospitals is increasing the workload of paramedics. High workloads will cause saturation and fatigue. In addition, an increase in the number of Covid-19 patients increases anxiety and depression will be infected when treating patients. Paramedics should also use personal protective equipment during shift guards which causes dehydration and discomfort. This situation can degrade the quality of service to patients. The study aims to measure the mental workload of paramedics by NASA-TLX (National Aeronautics and Space Administration Task Load Index) method and find out the factors that affect mental workload levels. This research is a quantitative research with a cross sectional approach. The research was conducted at Hospital X type C in Malang Regency in October 2020. The samples used were all 100 Hospital X paramedics. Research instruments in the form of questionnaires shared through Google Form. Data analysis is done with descriptive analysis and Chi-Square analysis with p value <0.05. The results found paramedics had a low mental workload of 1%, a moderate mental load of 3%, a high mental workload of 47%, and a very high mental workload of 49%. The Chi-Square test results found that age factors had an effect on the mental workload level of paramedics.
Study of Budget Efficiency Related to Covid-19 Hospitalization Claim Policy in X Hospital Malang: A Case Study Fitriasari, Nikma; Hariyanto, Engelbert; Kodriyah, Lailatul; Retno Suryaningati, Engelbertha; Silvaira, Natasya
Jurnal Kedokteran Brawijaya Vol. 33 Supplement 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.01.8s

Abstract

Coronavirus Disease 2019 (Covid-19) infection spread rapidly to more than 114 countries. Covid-19 spreading has a tremendous effect socially and economically, Indonesia included. Indonesian Government was issuing regulations about Technical Claim Instructions for anticipation. This Technical Claim Instruction was regulated on Keputusan Menteri Kesehatan (KMK) No HK 01.07/Menkes/238/2020, then renewed on KMK No HK.01.07/Menkes/446/2020. The purpose of this research is to analyze budget efficiency related to the change of Covid-19 hospitalization claim regulation. The research was done retrospectively, using secondary data such as claims and patient's medical records. Research conducted in October 2020 on X Hospital. The research sample used was every Covid-19 patient from March to September 2020 totaling 146. The data were analyzed using chi-square with the result showing that there is no correlation between changes of technical claim regulation with budget efficiency.
Factors Causing Outpatient Long Waiting Time at Outpatient Polyclinic of X Hospital Prasetyo Anggun Wicaksono, Achmad Rizki; Vindhya Putri, Aryani; Melani, Asti
Jurnal Kedokteran Brawijaya Vol. 33 Supplement 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.01.3s

Abstract

The long waiting time at the outpatient polyclinic is challenging at various hospitals. Waiting too long at the outpatient polyclinic will decrease patient satisfaction, so hospitals must continue improving quality service. Therefore, this study aimed to discover the causes of outpatient prolonged waiting time and solutions to these problems. This research was qualitative research conducted at X Hospital in Malang. The research sample was five participants. In this study, direct interviews, FGDs, and questionnaires were used. Factors causing prolonged waiting time for outpatient services at X Hospital that were not yet effective or still exceeded the minimum standard of hospital services were obtained through observation and Focus Group Discussions (FGDs); and the three root causes compiled using a fish diagram were no online registration and online queues, no Standard Operating Procedure regulating delays in the arrival of specialists for outpatient care, and a limited number of human resources. An alternative solution to the root of the problem was the creation of a Standard Operating Procedure that specifically regulates delays in specialist doctors at the outpatient polyclinic, creating WhatsApp online registration, and increasing the number of human resources in the outpatient polyclinic registration desk.
Solutions to Overcome Burnout Symptoms in Nurses in the Covid-19 Isolation Room Kurniawan, Sylvia Jessy; Gede Utara Hartawan, I Gusti Agung; Rusca Putra, Kuswantoro
Jurnal Kedokteran Brawijaya Vol. 33 Supplement 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.01.2s

Abstract

The Covid-19 pandemic has left healthcare workers working in uncertain and stressful situations to care for all patients with disabilities. The second wave of the Covid-19 pandemic that swept across the world caused many nurses in health facilities to experience fatigue in carrying out their duties. This study aims to determine the cause of burnout symptoms in isolation room nurses in the Covid-19 pandemic. The study was conducted at X Hospital in September-October 2021. The design of this study was descriptive analysis. Observations were made on the service system, data, and environment of the Covid-19 isolation room at X Hospital. Interviews and discussions were conducted with the head nurse, the head of the occupational safety and health committee, and the head of nursing medical services related to nurse burnout in the isolation room. 67.74% experienced emotional exhaustion in the medium and high categories in isolation room nurses in the second wave of the Covid-19 pandemic caused by a lack of staffing. The solution to detect and overcome burnout is to conduct mental health checks and regular medical check-up programs for further treatment by considering the comfort factor and high functional value.
Factors of Incomplete Inpatient Medical Records Filling at Dr. H. Slamet Martodirdjo Regional General Hospital Pamekasan Fajar, Achmad; Holipah, Holipah; Handayani, Ike
Jurnal Kedokteran Brawijaya Vol. 33 Supplement 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.01.4s

Abstract

Hospitals have an important role in improving health status by providing quality services, including complete medical record data and information. Complete and accurate medical records can be used for health care and patient treatment, evidence in law enforcement, medical discipline and medical ethics, educational and research purposes, basis of payment for health care costs, and health statistical data. This study aimed to identify the factors causing the incomplete filling of inpatient medical records at Dr. H. Slamet Martodirdjo Regional General Hospital Pamekasan. This research applied the descriptive observational method, with data collected through secondary data analysis using document studies and problem exploration using focus group discussions (FGD). The document study was conducted on 80 samples of inpatient medical records, while the FGD was conducted by inviting the head of the planning department, medical records officer, and 8 heads of inpatient wards to find out the causes and solutions for incomplete medical record files. The study results found that the number of incomplete medical records was 76.25%, with the highest percentage of incompleteness due to doctors, pharmacists, and nurses. The main problem causing the incompleteness of medical records was professional caregivers (PPA) who lacked discipline. The solutions obtained were management meetings and evaluations to professional caregivers, constructing policies that regulate reward and punishment systems, monitoring the checklists of medical record completeness, and routine evaluation of medical record files.
Root Cause Identification of Incomplete Medical Records Filing in Outpatient Clinic at Hospital X Malang City Perdana, Yudha; Imam, Cecilia Widijati; Al Rasyid, Harun
Jurnal Kedokteran Brawijaya Vol. 33 Supplement 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.01.5s

Abstract

Completeness of medical records is one indicator of the quality of health services in hospitals. The completeness of medical records at X Hospital still does not meet the national standards that have been set. The purpose of this study was to identify the root cause of the incompleteness of the outpatient medical record document at Hospital X Malang City. This study used a descriptive research design by reviewing medical record documents and FGDs. Document review was conducted on 111 medical records taken by random sampling. Identification of the root of the problem is carried out through FGD activities by applying the 5 Why's. The results of the FGD showed that there were three factors that contributed to the incompleteness of medical records at X Hospital, namely humans, machines, and methods. The root of the problems identified were not having electronic medical records, the number of patients was not proportional to the allocation of time for doctor's services, medical and nursing assessment sheets were combined into 1 sheet, lack of knowledge of doctor assistants, and quality indicators and telemedicine SOPs that were still not differentiated from outpatient clinics.
Factors Affecting Decreasing Patient Visits at Ob-Gyn Polyclinic of Outpatient Installation of “X” Hospital Suryandewi, Made Ayu Cintya; Dwi Harjayanti, Nofita; Seyijowati, Nanik
Jurnal Kedokteran Brawijaya Vol. 33 Supplement 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.01.7s

Abstract

In early 2020, the SARS-CoV-2 or Covid-19 outbreak resulted in decreasing number of patient visits at “X” Hospital. “X” Hospital has set a target of health services in the outpatient installation as many as 5,500 patient visits per month, but the 2020/2021 data showed a downward trend in patient visits, with the most significant decline in the Ob-Gyn polyclinic that reached 50%. Several factors could cause this decline, including the suboptimal promotion of the hospital's leading programs, a suboptimal response from the customer service officers, specialist doctors who do not only work at “X” Hospital that causes priority clashes, unclear signboards at the hospital, an uncomfortable waiting room at the outpatient polyclinic, patients who often cancel the visits, faulty online registration, and no patient satisfaction measurement in the outpatient installation. These situations will eventually cause increasing operational costs. This study aimed to determine the factors that caused decreasing patient visits at the Ob-Gyn polyclinic of “X” Hospital. This research used questionnaires distributed to patients in the Ob-Gyn polyclinic totaling 135 respondents and google forms distributed to the employees of “X” Hospital. The collected data were processed using descriptive statistics. From the study results, the three main factors that caused the decreasing patient visits are the suboptimal promotion of the hospital's leading programs, the suboptimal response of the customer service officers, and the absence of patient satisfaction measurement at the outpatient installation.

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