cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
Fakultas Kedokteran Universitas Brawijaya Gedung Graha Medika Lt. 1, Ruang 104
Location
Kota malang,
Jawa timur
INDONESIA
Jurnal Kedokteran Brawijaya
Published by Universitas Brawijaya
ISSN : 02169347     EISSN : 23380772     DOI : http://dx.doi.org/10.21776/ub.jkb
Core Subject : Health,
Medicine & Pharmacology
JKB contains articles from research that focus on basic medicine, clinical medicine, epidemiology, and preventive medicine (social medicine).
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 782 Documents
 74   75   76   77   78 
Thromboelastography Profile of Covid-19 Patients Before and After Convalescent Plasma Therapy Administration Fatonah, Siti; Xaveria, Xaveria; Hartanti, Khoirunisah Dwi; Purnamasari, Putri; Ningtyas, Denina Setya; Ramadhani, Saskia
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.11

Abstract

In Covid-19 patients, coagulopathy disorder is commonly characterized as hypercoagulable, although hemorrhagic complications can arise. However, thromboelastography (TEG) is an examination tool with the ability to assess the complete hemostasis process, including primary, secondary, and fibrinolysis stages, closely resembling the in vivo coagulation process. Therefore, this study provides a descriptive analysis of the hemostatic state of Covid-19 patients before and after administration of convalescent plasma therapy using TEG. In this study, the blood sample was collected from 21 Covid-19 patients at RSSA Malang from June to November 2020, followed by a TEG examination, which was performed on the first day of admission and after convalescent plasma therapy administration. The results were analyzed descriptively. Before convalescent plasma therapy, coagulation index (CI) analysis of TEG results in 21 patients showed that 62% exhibited normocoagulability, 23.8% were hypercoagulable, and 14.2% used hypercoagulability. While TEG results after convalescent plasma therapy showed that 71.4% were normocoagulable, 4.7% hypocoagulable, and 23.9% hypercoagulable. Based on TEG parameters, R, K, and MA, before administration of convalescent plasma therapy showed decreased platelet function by 38%, primary fibrinolysis by 5%, secondary fibrinolysis by 10%, platelet hypercoagulability 5%, and 43% was normal. Coagulopathy profile after convalescent plasma therapy showed decreased platelet function by 24%, secondary fibrinolysis by 10%, platelet hypercoagulability by 10%, enzymatic hypercoagulability by 5%, enzymatic and platelet hypercoagulability by 5%, and 48% was normal. TEG in Covid-19 patients showed a hypercoagulable state before and after administration of convalescent plasma therapy
Congenital Orbital Teratoma of the Newborn: A Rare Case Report Yuliawati, Putu; Wetarini, Krisnhaliani; Sutyawan, I Wayan Eka; Surasmiati, Ni Made Ayu; Utari, Ni Made Laksmi; Sunariasih, Ni Nyoman
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.19

Abstract

Congenital orbital teratoma is a rare and complex congenital anomaly due to abnormal tissue growth within the orbit. This case report aims to highlight the significance of early prenatal screening in identifying congenital orbital teratoma and its potential complications. A 6-day-old male newborn presented with macrocephaly and a unilateral massive protrusion of the left eye. Prenatal ultrasonography performed at 36 weeks gestation showed a suspicion of fetal craniofacial mass. Further brain CT scan revealed an orbital heterogeneous mass, with calcified components dominantly in the anterior and middle cranial fossa into the left orbit, which was subsequently diagnosed as congenital orbital teratoma associated with non-communicating hydrocephalus. This finding prompted an urgent ventriculoperitoneal (VP) shunt. Unfortunately, despite prompt intervention, the patient passed away after the procedure. Pathological examination was compatible with an immature teratoma. Multidisciplinary management is warranted to improve diagnostic screening and refine management strategies for better outcomes in such cases.
Identification of Gram Negative Bacteria in the Urine of Catheterized Patients at Referral Hospital in Ternate Waraningsih, Septiana; Do Toka, Wahyunita; Dahlan, Muhammad; Rachman, Ismail
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.5

Abstract

Infections can occur anywhere and often occur usually sourced from hospitals. Nosocomial infection is an infection caused by various microorganisms, one of which is bacteria originating from the hospital environment. Gram-negative bacteria, especially the Enterobacteriaceae family, are the main bacteria that cause nosocomial infections. One of the common infectious diseases in health care is urinary tract infection and some UTIs are caused by catheter insertion. This research aimed to identify gram-negative bacteria in the urine of catheterized patients at RSUD Dr. H. Chasan Boesoirie, a referral hospital in Ternate. The research method is descriptive observational with a cross sectional approach using a total sampling technique obtained 83 samples from November 14, 2023 to December 17, 2023. The results showed that 7 samples (8.4%) were identified as positive for gram-negative bacteria with 7 types of bacterial species and the highest percentage of bacteria was Escherichia coli (33.4%). The use of urinary catheters was mostly female (55.4%) with the highest age in the age group 56-65 years (34.9%) and the duration of urinary catheter use was mostly in samples with a duration of <72 hours (90.4%). In conclusion, gram-negative bacteria were identified in the urine of catheterized patients.
Left Lobe Hepatocellular Carcinoma in Non-Alcoholic Fatty Liver Disease Patient: A Case Report Inayah, Ninda Nurul; Astariyani, Thaibah; Batubara, Raya Henri; Nikita, Ester Grace; Irwan, Khair El Nisa; Putri, Kirei Aulia; Handayani, Lisa; Palambang, Sira Sappa
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.20

Abstract

Hepatocellular Carcinoma (HCC) is the second most common cause of death from cancer worldwide, affecting more men than women with a ratio of 2:1. Approximately 70–90% of HCC patients have risk factors such as chronic liver disease and liver cirrhosis. Another significant risk factor is non-alcoholic fatty liver disease (NAFLD). We report a case of left lobe hepatocellular carcinoma in a 54-year-old woman who presented with heartburn and shortness of breath, with a history of hypertension but no alcohol consumption. Chest X-ray revealed cardiomegaly without pulmonary congestion. A whole abdominal CT scan identified a left lobe hepatic tumor measuring ± 11x12x13 cm. Pathology examination revealed an epithelial mass with infiltrative, trabecular, acinar, and solid arrays, indicative of a malignant liver tumor.
The Effectiveness of Silicon Wound Dressing for the Healing Process of Contaminated Abrasions Limpat Wihastyoko, Herman Yosef; Siswoyo, Devira; Arviansyah, Arviansyah; Siswanto, Yudi; Agustina, Wilma; Sintaningrum, Elisabeth Prajanti
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.16

Abstract

Wounds are skin disorders caused by pathological processes. Abrasion wounds are a type of acute injury. One of the contributing factors is traffic accidents. More than 1.2 million people died as a result of traffic accidents, while 20-50 million others suffered injuries. Choosing the proper dressing can determine wound healing. This case study aims to determine the effectiveness of silicone wound dressing in the healing process of contaminated abrasion wounds. Contaminated abrasion wounds are contaminated by dirty materials, which potentially cause infection. This case report describes four patients, Mrs. W, Mrs. K, Mr. Y, and Mr. M., who suffered abrasions on the face. Their wounds were cleaned in the operating room under general anesthesia. A silicone wound dressing is applied as the primary dressing. The secondary dressing depends on the amount of the exudate. On the 3rd day after the surgery, the wounds looked dry, so they were cleaned and reapplied with the silicone dressing. On the 7th day, after applying silicone wound dressing, the wound had epithelialized. Silicone wound dressing is a modern type of dressing that is effective for acute wounds as it provides a barrier against external contamination. Our sample shows that wound are abrasion contaminated. The result of silicone wound dressings applied was shown accelerate the wound healing process. Modern dressings accelerate wound healing 20% to 40% faster than conventional dressings, such as gauze, tulle, or gauze.  
The Impact of Obesity on Dysmenorrhea and Lower Urinary Tract Symptoms in Adenomyosis Patients Anggraeni, Asih; Insan Ksyatria, Yudhistya Ngudi; Baidlowi, Akhmad Ikhwan
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.6

Abstract

Obesity poses a substantial health challenge globally, affecting various aspects of reproductive health, including adenomyosis. Adenomyosis, characterized by the presence of endometrial tissue within the myometrium, commonly affects women during their reproductive years, leading to symptoms such as dysmenorrhea and lower urinary tract symptoms (LUTS). This study aimed to investigate the influence of obesity on dysmenorrhea and LUTS severity in adenomyosis patients, considering demographic factors such as age and educational levels as potential moderators. Forty-four adenomyosis patients participated in a cross-sectional study at Dr. Moewardi General Hospital in Surakarta City of Indonesia, between April and September 2023. Diagnosis was confirmed using 2D Transvaginal Ultrasound (2D-TVUS). Obesity was defined using Body Mass Index (BMI) categories, and dysmenorrhea and LUTS were assessed using the Numerical Rating Scale (NRS) and modified International Prostate Symptom Score (IPSS) questionnaire, respectively. Statistical analyses included Pearson correlation. Results indicated a significant positive correlation between obesity and dysmenorrhea (rho = 0.256, P = 0.049) and LUTS (rho = 0.292, P = 0.029). Age and educational level did not significantly moderate these relationships, emphasizing the independent influence of obesity on symptom severity. In conclusion, obesity significantly impacts the severity of dysmenorrhea and LUTS in adenomyosis patients, highlighting the need for tailored management strategies that address both hormonal and inflammatory pathways.
A Complex Pediatric Case: Cerebral Palsy Complicated by Severe Pneumonia and Atelectasis Gatiningrum, Anindita; Udin, Muchammad Fahrul
Jurnal Kedokteran Brawijaya Vol. 33 No. 3 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2022.033.03.11

Abstract

Cerebral palsy (CP) is a non-progressive motor and cognitive disorder resulting from brain injury during development. Cerebral palsy (CP) promotes the development of respiratory disorders, including pneumonia and atelectasis. In this case, an 8-year-old male with cerebral palsy presented with complaints of shortness of breath, intermittent fever, productive cough, and decreased appetite. His respiratory rate was 28 beats per minute, SpO2 was 85%, and temperature was 37°C. Chest X-ray showed right pleural effusion with atelectasis, pneumonia in the left lung, emphysematous lung, and thoracic scoliosis. Bronchoscopy examination showed total atelectasis in the middle lobe of the right lung, with Streptococcus mitis or Streptococcus oralis identified through microbiological examination. Individuals with CP are susceptible to respiratory diseases due to neuromuscular impairment of the laryngeal muscles. This impairment can progress to atelectasis and pneumonia, representing the most common respiratory complications in CP. 
The Correlation of Infection Prevention and Control Knowledge and ESBL Carriage Rate among Healthcare Workers in a Hospital in Indonesia Fanani, Navalia Azkarifda; Krisniawati, Nia; Wicaksono, Madya Ardi; Hestiyani, Rani Afifah Nur; Widhi, Anriani Puspita Karunia Ning
Jurnal Kedokteran Brawijaya Vol. 33 No. 3 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2025.033.03.3

Abstract

Extended-spectrum beta-lactamase (ESBL) is an enzyme resulting from bacterial gene mutations that can restrict the activity of beta-lactam antibiotics, such as penicillin, the first, second, and third generation of cephalosporin, and monobactam, except cephamycin and carbapenem. ESBL can cause healthcare-associated infections (HAIs). Infection prevention and control (IPC) is a comprehensive effort to prevent HAIs in healthcare facilities. This research investigated the correlation between IPC knowledge level and the incidence of extended-spectrum beta-lactamase (ESBL) producing bacteria carriers in hospital healthcare workers. This research was conducted as observational analytical research using the quantitative and cross-sectional approaches. The research used purposive sampling, involving 61 healthcare workers at Banjarnegara Islamic Hospital. Research instruments included a 24-item questionnaire assessing IPC knowledge and rectal swabs intended to detect the incidence of ESBL carriers using the CHROMagar™ ESBL medium. Most respondents have a relatively good understanding of IPC, with a median score of 16 (25%). Of the 61 rectal swab samples, eight incidences of ESBL carriers were identified (13%). The isolates of the recognized carriers consist of five Escherichia coli (63%), two Klebsiella pneumoniae (25%), and one Acinetobacter baumannii (12%). Statistical analysis using the Mann-Whitney hypothesis test with the SPSS software showed a significant value of 0.493. Therefore, there is no correlation between IPC knowledge level and the incidence of extended-spectrum beta-lactamase-producing bacteria carriers in hospital healthcare workers.
Predictive Value of CA-125 for Endometriosis Staging at a Tertiary Hospital in Indonesia Angelia Ratnasari, Affi; Budi Hastuti, Uki Retno; Ismiaulia, Vidya
Jurnal Kedokteran Brawijaya Vol. 33 No. 3 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2025.033.03.1

Abstract

Endometriosis, affecting around 176 million women globally, is typically diagnosed through invasive laparoscopic inspection and histological confirmation. Due to the invasiveness of this method, noninvasive diagnostic alternatives like serum CA-125 assays are gaining interest. This study aims to determine the correlation between the tumor marker CA-125 and the stages of endometriosis, as classified by the revised American Society for Reproductive Medicine (rASRM) score. Data were retrospectively collected from the medical records of 24 reproductive-age women diagnosed with endometriosis at Dr. Moewardi General Hospital in Surakarta City, Indonesia. The dataset included patient age, serum CA-125 levels, rASRM scores, comorbidities, and surgical history. Statistical analysis involved the use of Pearson Chi-Square tests for nominal variables and independent t-tests or Mann-Whitney U-tests for scaled variables to evaluate the association between endometriosis stages (grouped into Stage I-II and Stage III-IV) and CA-125 levels (categorized as normal or elevated). A significant correlation was observed between higher stages of endometriosis (stage III-IV) and elevated CA-125 levels (p=0.040). Additionally, normal CA-125 levels were significantly associated with lower stages of endometriosis (stage I-II) (p=0.046). Furthermore, an association was found between type 2 diabetes and elevated CA-125 levels (p=0.037). In conclusion, our study suggests that elevated CA-125 levels correlate with higher stages of endometriosis (stage III-IV) and type 2 diabetes, indicating its potential as a biomarker for endometriosis severity.
Catamenial Pneumothorax due to Suspected Thoracic Endometriosis Syndrome in a Woman with Adenomyosis and Cystoma Ovarii Antariksa, Genta; Dwikarlina, Intan; Sutrisno, Sutrisno; Yudhanto, Hendy Setyo
Jurnal Kedokteran Brawijaya Vol. 33 No. 3 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2025.033.03.10

Abstract

Catamenial pneumothorax (CP) is a recurrent spontaneous pneumothorax during the menstruation period and is often associated with thoracic-pelvic endometriosis. This case study reported a 39-year-old woman who presented with recurrent shortness of breath, particularly during menstruation. The patient also experienced severe dysmenorrhea and difficulty getting pregnant. Despite a negative sputum test, a history of chest tube insertion and tuberculosis treatment were identified. Elevated levels of the CA-125 marker were observed in a previous examination. Physical examination revealed decreased fremitus sounds on the mediobasal side, chest expansion, and right lung breath sounds. The plain radiograph displayed a visceral pleural line, air-fluid level appearance, and the collapse of the right hemithorax accompanied by fibrosis. The patient underwent inpatient treatment and had a chest tube inserted. A decortication thoracotomy procedure was performed, and anatomical pathology microscopic examination of the right lung tissue revealed a non-specific chronic inflammatory process accompanied by fibrosis.

Page 76 of 79 | Total Record : 782

 74   75   76   77   78 

Filter by Year

2002 2025


Reset
Filter By Issues
All Issue Vol. 33 No. 4 (2025) Vol. 33 No. 3 (2025) Vol. 33 No. 2 (2024) Vol. 33 Supplement 1 (2024) Vol. 33 No. 1 (2024) Vol. 32 No. 4 (2023) Vol. 32 No. 3 (2023) Vol. 32 No. 2 (2022) Vol. 32 No. 1 (2022) Vol. 32 Supplement 1 (2022) Vol. 32 Supplement 1 (2021) Vol 31, No 4 (2021) Vol. 31 No. 4 (2021) Vol. 31 No. 3 (2021) Vol 31, No 3 (2021) Vol. 31 Supplement 2 (2021) Vol 31, No 2 (2020) Vol 31, No 1 (2020) Vol 30, No 4 (2019) Vol 30, No 3 (2019) Vol 30, No 2 (2018) Vol 30, No. 1 (2018) Vol 29, No. 4 (2017) Vol 29, No. 3 (2017) Vol 29, No 3 (2016) Vol 29, No. 2 (2016) Vol 29, No 1 (2016) Vol 28, No 4 (2015) Vol 28, No 3 (2015) Vol 28, No 2 (2015) Vol 28, No 2 (2014) Vol 28, No 1 (2014) Vol 27, No 4 (2013) Vol 27, No 3 (2013) Vol 27, No 2 (2012) Vol 27, No 1 (2012) Vol 26, No 4 (2011) Vol 26, No 3 (2011) Vol 26, No 2 (2010) Vol 26, No 1 (2010) Vol 25, No 3 (2009) Vol 25, No 2 (2009) Vol 25, No 1 (2009) Vol 24, No 3 (2008) Vol 24, No 2 (2008) Vol 24, No 1 (2008) Vol 23, No 3 (2007) Vol 23, No 2 (2007) Vol 23, No 1 (2007) Vol 22, No 3 (2006) Vol 22, No 2 (2006) Vol 22, No 1 (2006) Vol 21, No 3 (2005) Vol 21, No 2 (2005) Vol 21, No 1 (2005) Vol 20, No 3 (2004) Vol 20, No 2 (2004) Vol 20, No 1 (2004) Vol 19, No 3 (2003) Vol 19, No 2 (2003) Vol 19, No 1 (2003) Vol 18, No 3 (2002) Vol 18, No 2 (2002) Vol 18, No 1 (2002) Article in Press 2 Article in Press More Issue