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Folia Medica Indonesiana The Unit of Journal Consortium and Folia Medica Indonesiana Faculty of Medicine, Universitas Airlangga Jl. Prof. Dr. Moestopo No.47, Pacar Kembang, Kec. Tambaksari, Surabaya, Jawa Timur 60132, Indonesia
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INDONESIA
Folia Medica Indonesiana
Published by Universitas Airlangga
ISSN : 23558398     EISSN : 2599056X     DOI : https://doi.org/10.65346/2958-4515.2401
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience
Folia Medica Indonesiana, as indicated by its name, focuses on publishing good quality articles about research and education on health science and medicine in Indonesia. However, due to the fast growth of science and knowledge in these fields, we also welcome submitted articles from around the world, especially the ones that contain related matters from lower-middle income countries. Folia Medica Indonesiana is an open-access, peer-reviewed journal that is published online at least four times a year. The scope covers various aspects of basic medical sciences includes anatomy, physiology, pathology, microbiology, pharmacology, and molecular medicine) and clinical medicine (covers specialties like internal medicine, surgery, pediatrics, oncology, psychiatry, etc). We highlight the pathology and potential treatment of metabolic syndromes and infectious diseases. Folia Medica Indonesiana also encourages the publication of articles about health education. The scope includes, but is not limited to, articles that emphasize on preventive education on certain diseases in a community, also research report of various materials and/or methods to develop medical education. We recognize the importance of this type of articles to be published alongside the assigned topic in each of our yearly issues, to provide our readers with updated information in medical sciences’ research and education simultaneously.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 571 Documents
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Effect of Cancer Related Fatigue tTo the Level of Independence of Cancer Patients and Caregiver Stress Level Werdani, Yesiana Dwi Wahyu
Folia Medica Indonesiana Vol. 54, No. 2
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Abstract

Chemotherapy/radiation in cancer patients causes cancer-related fatigue (CRF). It affects the level of independence of patients' activity of daily living (ADL). Thus, the responsibility of caregivers will be higher and it impacts on caregiver stress level. The aim of this study was to prove the effects of CRF on independence level of cancer patients and caregivers' stress level. This study used analytical associative design. The population was cancer patients and caregivers in Yayasan Kanker Indonesia in East Java. The number of samples were 30 cancer patients and 30 caregivers, taken by total sampling method. The assessment was based on instrument brief fatigue questionnaire, activity of daily living based on Katz, and caregiver stress on self assessment questionnaire. The effects of CRF on the level of independence were indicated by p=0.000, and the levels of independence of the caregiver stress level were indicated by p=0.000. As a conclusion, the failure of muscle function due to CRF can affect the independence of patient's ADL fulfilling, so caregiver should take much time to treat patient and it affects on the increased stress level of caregiver.
Blood Type and Blood Pressure Correlations to Body Mass Index in Young Adults Suwito, Bambang Edi; Kalanjati, Viskasari P; Abdurachman, Abdurachman
Folia Medica Indonesiana Vol. 56, No. 3
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Abstract

Specific ABO blood type was reported to the higher risk of having overweight and obesity. The laters had also been suggested to correlate to blood pressure. Here we studied blood type and blood pressure amongst seemingly healthy university students of IIKBW, Kediri to understand their correlations to the body mass index (BMI). The blood typing (ABO typing, Eryclone®) and blood pressure (automated digital sphygmomanometer) of 74 male and 76 female were measured in duplicate accordingly. The BMI was analysed from the student's body weight and height using a digital balance and a microtoise staturemeter, respectively. Data were analysed using SPSS 17 with p<0.05 level of significance. There were 18.7% students have A blood type, 31.3% students were B type, 44% were O and 6.0% with AB blood type. There were 30.7% students with obesity, 18% overweight, 36% normal weight and 15.3% underweight. There were 4.7% had a hypertension, 28.7% pre-hypertension, and 66.7% were normal. No significant correlations found between BMI or the blood pressure to any specific ABO blood type, except between the blood pressure and the AB blood type (r=-0.179, p=0.03). However, there was a significant correlation between BMI and blood pressure (r=0.327, p=0.000). We observed no significant associations between any specific ABO blood type with the BMI and blood pressure. However, high blood pressures amongst students with obesity were found. Males were more common to suffer from obesity and high blood pressure than females.
Analysis on the pattern of using the service of removable partial denture making in a dental laboratory in surabaya Setyowati, Okti; Kusdarjanti, Endang
Folia Medica Indonesiana Vol. 52, No. 4
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Abstract

The making of removable denture is performed by a dental laboratory. To facilitate the identification, according to Kennedy classification, classes are divided onto groups, the Kennedy class I, II, III and IV. To suit with the needs of the dental laboratory tasks commonly done, priority are necessary for common cases and should to be taught to students of Dental Health Technology Diploma. In Surabaya, research of various cases of removable partial denture with the various Kennedy classifications has never been done before. This study was to analyze the pattern of service for the removable partial denture manufacture in dental laboratory at Surabaya (2011 – 2013). The research is an observatory analytic. The population is all dental laboratories located around the campus of the Faculty of Dentistry Airlangga University Surabaya. The sample was the whole population is willing to become respondents. Sampling by total sampling. The method of collecting data using secondary data from a dental laboratory in Surabaya from 2011 until 2013. The note is cases removable denture according to the classification of Kennedy that Kennedy Class I, II, III and IV. Also of note kinds of materials used to make the denture base that is heat cured acrylic resins, thermoplastic resins and metals coherent. The data is a compilation table charting the frequency until needed, then analyzed using cross tabulation. Mostly denture type is flexible type and the least is metal framework. Most cases by classification Kennedy is followed by class II class III and class II and more recently is the fourth. In conclusion, in 2011 and 2013 the manufacture of removable partial dentures according to the classification of Kennedy Class III is the most common in both the upper arch and lower jaw, followed by Class II, Class I and Class IV. In 2012 which is the highest grade III followed by class II, class IV and class I. The denture type most used is a flexible denture, followed acrylic denture and the last is the metal framework.
Case report: retrograde approach for cto lesions: serial case Oktaviono, Yudi Her
Folia Medica Indonesiana Vol. 52, No. 4
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Abstract

Chronic total occlusion recanalization still represents the final frontier in percutaneous coronary intervention. Successful revascularization is associated with improved long-term survival, reduced symptoms, improved left ventricular function and reduced need for coronary bypass surgery. Retrograde chronic total occlusion recanalization has recently become an essential complement to the classic antegrade approach. Retrograde approach through the collateral channel has been recently proposed and has the potential to improve the success rate of percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) lession of the coronary arteries. We report several cases of successful CTO recanalization procedure using retrograde approach in Soetomo Hospital.
Front Matter Vol. 58 No. 2 June 2022 Indonesiana, Folia Medica
Folia Medica Indonesiana Vol. 58, No. 2
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Abstract

Oral Health Status and The Body Mass Index in Young Adults Rahmawan, Dzanuar; Kalanjati, Viskasari P; Abdurachman, Abdurachman
Folia Medica Indonesiana Vol. 56, No. 4
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Abstract

Poor oral health has been reported to correlate to the body mass index (BMI) of the overweight and the obesity groups. These has yet widely studied in Indonesia. The aim of this study was to analysed the oral health, socioeconomy factors (FSE) and the BMI in the seemingly healthy university students in Kediri aged 18-21 years old. This cross-sectional study was conducted amongst male and female students of IIKBW, Kediri, Indonesia (n=150). We analysed their BMI from the body weight and height (kg/m2). Their oral health was determined by the DMFT index (decayed missing filled teeth index), the stimulated salivary flow rate (SSFR) and the gingival index (GI). FSE studied include father's highest education and monthly income, tooth brushing frequency in a day and dental floss habitual use. Data was analysed using SPSS 17 with level of significance of p<0.05. No significant differences in BMI, DMFT index, SSFR and GI respectively (p=0.411;p=0.037, p=0.880, p=0.142) between male and female groups. No significant corelation BMI with DMFT index, SSFR and GI, respectively (p=0.340, p=0.420, p=0,446). FSE are not significantly correlated to either the BMI, DMFT index, SSFR orGI (p > 0.05). There were 41.8% of males and 57.8% of females have "bad” score of DMFT and 98.6% of males and 92.1% of females have "bad” score of GI; 4.1% of males and 2.6% of females have low score of SSFR.Although we found no significant differences in the BMI and oral health parameters between genders, in the seemingly healthy young adults oral health hygiene could be compromised as found in the current study indicated by bad scores of DMFT, SSFR or GI. Here we found that either BMI or FSE was not significantly correlated to any of oral health parameters measured in the current study.
Increased HIF-1alpha And VEGF Expression Found in Various T Stages of Clear Cell Renal Cell Carcinoma Octavianda, Yohana; Rahaju, Anny Setijo
Folia Medica Indonesiana Vol. 54, No. 2
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Abstract

There is an increase in renal cell carcinoma in males aged over fifty years with smoking risk factors. Clear cell renal cell carcinoma is the most common malignant tumor found in the kidneys that have an aggressive nature. This carcinoma is classified according to TNM into T1, T2, T3 and T4 stages. The higher the T stage, the worse the prognosis of the patient, as it involves the role of the HIF-1a transcription factor accumulated under hypoxic condition due to inactivation of VHL, thus activating VEGF. So far, clear cell renal cell carcinoma frequently found in smoking males of fifth decade of age or older has not been explained.. An observational analytic study was conducted on the sample of paraffin blocks of patients with clear cell renal cell carcinoma in 2010-2016. T1, T2, T3, and T4 stages of 9 samples, 12 samples, 12 samples and 6 samples, respectively, were collected in Anatomic Pathology Laboratory, Dr. Soetomo Hospital, Surabaya. Detection of HIF-1a and VEGF expression was performed using immunohisto-chemical immunity with HIF-1a and VEGF antibodies. The results were analyzed statistically by Kruskal-Wallis and Mann-Whitney methods. The correlation between HIF-1a and VEGF in T stages was analyzed using Spearman method. There was a difference of HIF-1a expression between stage T1 with T2, T1 with T3, T1 with T4 (p=0.041, p=0.000, and p=0.002), stage T2 with T3 and stage T2 with T4 (p=0.001, and p=0.013). There was a difference in VEGF expression in stage T1 with T2, T1 with T3, T1 with T4 (p=0.007, p=0.000, and p=0.002), and stage T2 with T3 (p=0,001). There was a correlation between HIF-1a and VEGF expressions with all T stages (rs=0.624 with p 0.000). As a conclusion, the higher the stage of T, the higher the expression of HIF-1a and VEGF. The higher the levels of HIF-1a and VEGF, the worse the prognosis of clear cell renal carcinoma. HIF-1a and VEGF play a role in the pathogenesis of clear cell renal cell carcinoma. Thus, HIF-1a and VEGF can be developed as prognostic markers. Increased Hif-1aAnd Vegf Expression Found In Various T Stages Of Clear Cell Renal Cell Carcinoma
Characteristics of Primary Glaucoma in Eye Outpatient Clinic of RA Basoeni Hospital, Mojokerto, Indonesia Rayungsista, Awina
Folia Medica Indonesiana Vol. 54, No. 3
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Abstract

Glaucoma is the third cause of blindness after cataracts and refractive disorders. About 4.5 million people worldwide suffer from blindness due to primary glaucoma. A study on the characteristics of primary glaucoma in Eye Outpatient Clinic at RA Basoeni Mojokerto Hospital in the period of January-December 2016 had been performed in a descriptive cross sectional retropective study, observing: glaucoma type, gender, age, laterality, visual acuity, and intra ocular pressure (IOP). The type of primary glaucoma that most patients experienced was primary angle closure glaucoma. In primary open-angle glaucoma, the number of male patients was almost the same as female patients. Whereas, in primary angle closure glaucoma, there were more female patients than male. Primary glaucoma patients, both open and closed, were mostly >60 years old. Both primary open and angle closure glaucoma occurred mostly bilaterally. The highest visual acuity of primary glaucoma patients was mild vision loss and near-total vision loss. More glaucoma patients had IOP >21 mmHg, both in right and left eye.
Back Matter Vol. 56, No. 2 June (2020) Matter, Back
Folia Medica Indonesiana Vol. 56, No. 2
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Abstract

The difference of blood pressure and arterial stiffness after intake of arabica and robusta coffee in controlled hypertension Pikir, Budi S; Andrianto, Andrianto; A, Ford Ance
Folia Medica Indonesiana Vol. 53, No. 3
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Abstract

Potential mechanisms of caffeine promote large artery stiffness and associated with increased morbidity and mortality of cardiovascular disease. To find the difference of blood pressure and arterial stiffness after intake of arabica and robusta coffee in controlled hypertension, a quasi-experimental study was done enrolling 24 controlled hypertension and 24 normotensive subjects collected by purposive sampling. Subjects received ± 10,6 g caffeinated coffee in 150 ml water with crossover protocol twice in 5 days. The assessment of arterial stiffness by obtaining ultrasound 2D image of common carotid artery then was calculated with beta stiffness index. Blood pressure and arterial stiffness was measured before coffee intake and again at 30 to 60 minutes thereafter. In controlled hypertension, significant differences were found between initial systolic blood pressure (SBP), 30 and 60 minutes after arabica (p 0,002) and robusta (p 0,012) intake; between diastolic blood pressure (DBP), 30 and 60 minutes after of arabica (p 0,004) and robusta (p 0,025) oral administration; and between initial beta stiffness index, 30 and 60 minutes after arabica (p 0,018) oral administration. However, no significant difference was found between initial beta stiffness index, 30 and 60 minutes after robusta (p 0,104) oral administration. No significant difference was found in all variables after arabica and robusta intake. Significant differences were found in blood pressure after arabica or robusta intake and in arterial stiffness after arabica intake. However, no significant differences were found in arterial stiffness after robusta intake and in all variables after arabica and robusta intake.

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