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Folia Medica Indonesiana The Unit of Journal Consortium and Folia Medica Indonesiana Faculty of Medicine, Universitas Airlangga Jl. Prof. Dr. Moestopo No.47, Pacar Kembang, Kec. Tambaksari, Surabaya, Jawa Timur 60132, Indonesia
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INDONESIA
Folia Medica Indonesiana
Published by Universitas Airlangga
ISSN : 23558398     EISSN : 2599056X     DOI : https://doi.org/10.65346/2958-4515.2401
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience
Folia Medica Indonesiana, as indicated by its name, focuses on publishing good quality articles about research and education on health science and medicine in Indonesia. However, due to the fast growth of science and knowledge in these fields, we also welcome submitted articles from around the world, especially the ones that contain related matters from lower-middle income countries. Folia Medica Indonesiana is an open-access, peer-reviewed journal that is published online at least four times a year. The scope covers various aspects of basic medical sciences includes anatomy, physiology, pathology, microbiology, pharmacology, and molecular medicine) and clinical medicine (covers specialties like internal medicine, surgery, pediatrics, oncology, psychiatry, etc). We highlight the pathology and potential treatment of metabolic syndromes and infectious diseases. Folia Medica Indonesiana also encourages the publication of articles about health education. The scope includes, but is not limited to, articles that emphasize on preventive education on certain diseases in a community, also research report of various materials and/or methods to develop medical education. We recognize the importance of this type of articles to be published alongside the assigned topic in each of our yearly issues, to provide our readers with updated information in medical sciences’ research and education simultaneously.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 571 Documents
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Case Report: Diagnosis and Treatment of Psychosomatic Gastritis at a Primary Health Clinic in West Surabaya, Indonesia Roosihermiatie, Betty; Isfandari, Siti; Fauzia, Yurika
Folia Medica Indonesiana Vol. 54, No. 2
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Abstract

Indonesia is highly populated of a total 238,452,952 people with 274,396 gastritis cases. However, psychosomatic gastritis was just reported by very few patients. Because of the common gastritis cases in Indonesia and with the act of Healthcare and Social Security Agency or BPJS, so primary health cares should diagnose and manage the cases. This study aimed to determine the diagnosis and management of psychosomatic gastritis at a primary health clinic in West of Surabaya. It was a case study. It was a case on a woman aged 45 years old. She was high school graduate, married and had a child. She experienced reflux gastritis and psychiatric condition of depression and anxienty disorders. She was treated by psychiatrist at the first time and self-medicated for the gastritis. After stopping visiting the psychiatrist, she had problems of gastritis in four months. Then, she was referred to internist and examined Ultra Sonography of abdominal organs with normal result. There was a conventional method to determine psychosomatic gastritis that consicting of life styles, psychologic factor, social factor, and behavior assessment. This patient was a local migrant who struggled to gain a better life in the city, had a trigger for his father's death, had a relatively low socioeconomic state and lived in a monthly boarding house, and was a part-time worker. First-line care should establish a psychosomatic diagnosis of gastritis and treat psychological disorders together with their somatic abnormalities. Thus, the first level of health services must provide holistic services consisting of physical, psychological and social aspects.
Epidemiology Study of Dengue Virus In Surabaya, Bogor, and Bangkalan, Indonesia 2008-2018 Soegijanto, Soegeng; Sucipto, Teguh Hari; Mulyatno, Kris Cahyo; Churrotin, Siti
Folia Medica Indonesiana Vol. 56, No. 4
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Abstract

Dengue virus (DENV) is mosquito-borne viral diseases, transmitted by the vector mosquitoes such as Aedes sp. Infection with four serotypes of DENV-1 to 4. Indonesia, dengue haemorrhagic fever (DHF) was first recognized in 1968 in the cities of Jakarta and Surabaya. In 2007, we started DENV surveillance in Surabaya supported by the joined program of the Japan Initiative for Global Research Network on Infectious Disease (J-GRID) established the Indonesia-Kobe University Collaborative Research Center for Emerging and Reemerging Infectious Diseases (CRC-ERID). The results of serotype and genotype, in Surabaya and Bangkalan are similar with previous result in Indonesia, but especially in Bogor similar with Japan 2014. This study showed the importance of continuous virus surveillance in dengue endemic areas, in order to understand the dynamic of dengue infection disease in Indonesia.
Dna isolation from human urine stain as an alternative material for personal identification examination Yudianto, Ahmad; Sispitasari, Yeti Eka
Folia Medica Indonesiana Vol. 52, No. 4
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Abstract

Accurate determination of personal identity is crucial for an investigation since any inaccuracy may lead to fatal consequences in the judicial process. Identification through DNA analysis involves somatic chromosomes and mtDNA. Each part of the human body can be taken as a specimen since every nucleated cell in the body of an individual has identical DNA sequence. To date, samples for identification through DNA analysis are obtained from blood stains, semen stains, bones, vaginal swab, buccal swab etc. In certain cases, urine stains on the clothing have frequently been overlooked. So far, personal identification through DNA analysis by the use of urine stains has not been commonly carried out. The present study detected bands in the loci CSF1PO, THO1, TPOX and 106bp-112bp amelogenin in all samples visualized from the results of Polymerase Chain Reaction (PCR) with Polyacrylamid Agarose Gel Electrophoreses-silver staining for exposure durations of 1, 7 and 14 days. However, for exposure duration of 20 days (the maximum in the study), bands were only detected in the loci THO1 and TPOX in all samples (100%), whereas the loci CSF1PO and 50% amelogenin exhibited obvious bands. This indicated that DNA analysis of urine stains through detection of the locus STR CSF1PO, THO1, TPOX exhibited different detection responses for different exposure durations assigned to the samples of urine stain. Successful detection of these loci was supported by the differences in amplicon product and GC content at each locus. Of the loci studied, the ratio of GC content of the primers, sorted from the lowest, were as follows: locus CSF1PO of 42.6 1%, TPOX of 56.25%, and THO1 of 63.83%. In conclusion, the loci THO1 and TPOX had the same probability of success in the STR examination compared with the locus CSF1PO.
Effectiveness and safety differences of isoxsuprine and nifedipine as tocolytics in the risk of preterm labor Oktavia, Nur; Yulistiani, Yulistiani; Markus, Unedo H; Mamo, Hendriette Irene
Folia Medica Indonesiana Vol. 53, No. 4
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Abstract

Premature labor is a cause of high rates of perinatal morbidity and mortality. The use of tocolytics is one of the efforts to handle the risk of preterm labor. Tocolytics which are widely used in Indonesia is isoxsuprine and nifedipine. The purpose of this study was to identify the difference of effectiveness and safety of isoxsuprine as tocolytics in the risk of preterm labor. This was an observational study in the form of a case study that was done in detail and depth to the patients who were diagnosed as imminent preterm labor. In conclusion, there were differences in the effectiveness and safety of isoxsuprine and nifedipine as tocolytics in the risk of preterm labor.
Hookworm in Stray Cats (Felis silvestris catus) as Cutaneous Larva Migrant Agent (CLM) in Humans Mahendra, Fadhil Ihsan; Soebaktiningsih, Soebaktiningsih; Prabawati, Risma Karlina
Folia Medica Indonesiana Vol. 58, No. 3
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Highlights : • Risk factors that can increase the incidence of CLM in humans include male sex, children aged <15 years, low-income people, and daily behaviour of walking outdoors without using footwear, especially on the sand. • Risk factors that play the most role in increasing the incidence of CLM in humans are walking outdoors without using footwear, especially on the sand. Abstract : Cats arethe host of a wide variety of microorganisms including ectoparasites and endoparasites.One of theendoparasites that infect cats is hookworm. The hookworms consists of two groups, the animal hookworms, and the human hookworms. The manifestation that can be caused by animal hookworms to humans is Cutaneous Larva Migrant (CLM). This study aimed to discover whether hookworm in stray cats (Felis silvestris catus) can cause CLM in humans. We performed a systematic search in Pubmed/Medline and Cochrane published between 2016 and 2021 with no restrictions by language, research country, or type of research design . The results of the analysis showed that the high level of hookworms infection in stray cats could increase the risk of CLM in humans. Based on the study, we could conclude that the high prevalence of hookworm infection in cats plays an important role in the increased risk of zoonoses in humans which in turn could also increase the prevalence of CLM in humans.
Impact of SYNTAX Scores on the Long-Term Outcomes of Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention for Left Main Coronary Artery Disease Murteza, Faiq; Albab, Chabib Fachry; Habibah, Almas Talida; Mas'udi, Achmad Fayyad; Pravitasari, Vemaniarti Lian; Rajanagara, Arya Satya; El-Ma'i, Zaha
Folia Medica Indonesiana Vol. 59, No. 4
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Abstract

The Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score was designed to predict the post-procedural risk associated with percutaneous coronary intervention (PCI) or surgical revascularization. This study aimed to evaluate the long-term outcomes of PCI and coronary artery bypass grafting (CABG) by comparing several existing studies. A systematic search was performed using the PubMed (MEDLINE) and ScienceDirect databases. This systematic review included studies that examined differences in the outcomes of PCI and CABG for left main coronary artery (LMCA) stenosis. This was a systematic review study in which we reviewed original cross-sectional and cohort studies. The search was conducted from February 1st until February 2nd, 2023. The quality assessment of the studies was carried out using the criteria outlined in the Newcastle-Ottawa Scale (NOS). According to the final assessment, all the original research included had a mean NOS score of 8, indicating excellent quality. The literature search yielded 1,675 studies, five of which were selected for the final analysis. A total of 5,494 patients underwent PCI and CABG. This study found that there were variations in outcomes among patients with low, medium, and high SYNTAX scores for long-term major adverse cardiac or cerebrovascular events (MACCE) and long-term mortality. However, similar outcomes were observed in long-term revascularization, long-term stroke, and long-term myocardial infarction (MI). This study concluded that patients with LMCA stenosis and SYNTAX scores ranging from low to high may have different long-term outcomes. CABG is associated with a lower incidence of mortality, repeat revascularization, MI, and MACCE compared to PCI. On the other hand, an association exists between PCI and a lower incidence of stroke.
Ferning and Schirmer Test 1 for the Detection of Grading Severity of Dry Eye Syndrome in Post Phacoemulsification Patients Zubaidah, Tengku Siti Harilza; Lubis, Rodiah Rahmawaty; Feriyawati, Lita
Folia Medica Indonesiana Vol. 58, No. 3
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Highlights: 1. Females were the most gender who suffer from dry eye syndrome than males. 2. Undergone phacoemulsification patients had frequent dry eye syndrome. 3. Post-phacoemulsification patients were not statistically significant between the Ferning and the Schirmer test. Abstract: Dry eye syndrome is a multifactorial disease on the surface of the eyeball characterized by loss of tear film homeostasis, which is associated with eye symptoms, where there is tear instability and hyperosmolarity, inflammation, and damage to the surface of the eye, as well as neurosensory disorders that act as the cause of this syndrome. The aim of this study was to identify relationship between the Ferning pattern and the Schirmer test 1 in post-phacoemulsification patients. The design of this study was an analytical observational study with a cross-sectional data collection method where the Ferning and Schirmer test 1 were examined to determine the severity of dry eye syndrome in post-phacoemulsification patients. The Ferning test was assessed according to Rolando's classification. In this study, it was found that the gender who suffer from dry eye syndrome are women. The most considerable age is age ≥ 60 years (56,7%). The results showed that the majority of patients experienced dry eyes measured with the Ferning test, and these results were following the previous Schirmer Test 1 examination. The Ferning and Schirmer tests were found to be abnormal in most of the subjects. It was found that there was a significant relationship between the Ferning pattern and the Schirmer test with the calculation of the t-value of 7.345 with a p-value of 0.001. There was a statistically significant difference between the results of Ferning and the Schirmer test in post-phacoemulsification patients.
Auricular Acupressure Effectively Reduces Labor Anxiety in Primigravidae by Increasing β-Endorphin Levels Setiawandari, Setiawandari; Saputra, Koosnadi; Waroh, Yuni Khoirul; Andarwulan, Setiana
Folia Medica Indonesiana Vol. 59, No. 3
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Abstract

Highlights: 1. Auricular acupressure at the Shenmen point is effective in reducing anxiety. 2. Auricular acupressure is more practical than body acupressure since it does not interfere with expectant mothers' mobilization. 3. As a non-pharmacological method, auricular acupressure is cost-effective, efficient, and effective in overcoming maternal anxiety during labor Abstract Anxiety is a common psychological symptom in expectant mothers, particularly among primigravidae during labor. There is a link between excessive anxiety and prolonged labor. One of the options to manage anxiety is the use of non-pharmacological methods. Numerous studies have investigated the effectiveness of auricular acupressure to treat anxiety, but few have examined its effect on anxiety biomarkers. Thus, the objective of this study was to analyze the effect of auricular acupressure targeting the Shenmen point on the levels of β-endorphins and anxiety among primigravidae during the first stage of labor. This experimental study used a pretest-posttest control group design. The research subjects were primigravidae in the first stage of labor at the independent midwife practice of Yefi Marliandiani in Surabaya, Indonesia. Among 40 primigravidae, 34 individuals met the inclusion criteria and were then equally divided into treatment and control groups using a simple randomization. The treatment group received auricular acupressure at the Shenmen point every 30 minutes for a duration of 5 minutes, while the control group practiced deep breathing relaxation. The anxiety levels were assessed using the Hamilton Anxiety Rating Scale. The β-endorphin levels were measured by drawing 3 cc of venous blood before (4 cm cervix dilation) and after (9–10 cm cervix dilation) treatment. The obtained data were analyzed using paired- and independent-samples t-tests. A decrease in the mean anxiety level was observed in the treatment group (18.59±7.52) relative to the control group (19.76±7.11), albeit not significant (p=0.64). Simultaneously, the average β-endorphin levels of the treatment group (355.4±224.7) increased compared to the control group (225.1±127.5), with a significant difference observed between the two groups (p=0.04). In conclusion, while both auricular acupressure at the Shenmen point and deep breathing relaxation are effective in reducing anxiety, the former is more prominent in its ability to increase β-endorphin levels.
Back Matter Vol. 55, No. 1 March (2019) Matter, Back
Folia Medica Indonesiana Vol. 55, No. 1
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The impacts of stimulation in protracted labor to cortisol levels and incidence of post-partum blues Soetrisno, Soetrisno; Respati, Supriyadi Hari; Sulistyowati, Sri; Kurniawan, Hendro
Folia Medica Indonesiana Vol. 53, No. 1
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Abstract

Delivery, induction, stimulation, cesarean section with the aid of a vacuum extraction, for example, can reduce maternal confidence on the smooth delivery process, as well as improve postpartum stress. These stressors stimulate the HPA axis (hypothalamus-pituitary-adrenal), so that the adrenal cortex produces more cortisol hormone, it can increase postpartum blues. The objective of this study was to analyze the effect of delivery stimulation on protracted labor on cortisol levels and the occurrence of postpartum baby blues. This was an experimental study of non-randomized post-test control group. The subject of the study 30 patients in labor taken consecutive sampling, divided into 2 groups (normal delivery and stimulation) each group consist of 15 patients. In stimulation delivery group, it is examined of cortisol serum levels after five days and then continued for postpartum blues occurrence measurement. Statistical analysis using t-test for differences in levels of cortisol and chi square for analyzing the effect on the occurrence of post-partum blues (a=0.05). Mean level of cortisol in delivery stimulation group is 40.29 ± 5.58, in normal delivery is 33.59 ± 11.17, with p=0.047, meaning there are significant differences both study groups. Stimulation delivery increases the occurrence of post-partum blues 5.50 times compared to normal delivery (OR=5.50 and p=0.028). Mean cortisol levels on post-partum blues higher at 42.90 ± 6.97 compared to no post-partum blues 30.14 ± 6.66, p=0:00, which means there are significant differences both groups. In conclusion, there was significant relationship between stimulation in protrated labor that increases cortisol serum level and post partum blues incidence.

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