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PharmaCine: Journal of Pharmacy, Medical and Health Science
Published by Universitas Singaperbangsa Karawang
ISSN : 27464199     EISSN : 27464199     DOI : https://doi.org/10.35706/pc.v7i1
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Veterinary
PharmaCine: Journal of Pharmacy, Medical, and Health Sciences is a peer-reviewed journal dedicated to scientific publications in the fields of pharmacy, medicine, and health sciences. PharmaCine is published biannually, in March and September, by the Undergraduate Pharmacy Program, Faculty of Health Sciences, Singaperbangsa University Karawang, in collaboration with the Indonesian Pharmacists Association (IAI). This journal serves as a forum for students, pharmacists, medical personnel, and other health professionals to update their knowledge and access scientific literature. PharmaCine publishes a range of articles, including meta-analyses, original research, reviews, and case reports. Submissions are peer-reviewed to ensure scientific rigor within the relevant field. The scope of the PharmaCine Journal encompasses various pharmaceutical, medical, and health science topics, including: Pharmacology Pharmacotherapy Clinical Pharmacy Pharmaceutical Technology Herbal Pharmacy Social Pharmacy Pharmaceutical Management Clinical Biochemistry Pharmacogenetics Pharmaceutical Chemistry Pharmaceutical Biology Public Health Sciences
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 76 Documents
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Kasus Temuan Produk Obat dan Makanan Ilegal Yang Dijual Melalui E-Commerce dan Korelasinya dengan Peraturan Badan Pengawas Obat dan Makanan Nomor 8 Tahun 2020 Nissa Hanum; Siti Nafisa; Siti Rohmah; Yumareta Anggun Nihan; Elvira Julia Ariyanto
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 5 No. 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.11066

Abstract

Background: The advancement of information and communication technology has led society to rely on the use of communication devices and the internet. The global increase in e-commerce, coupled with the growth of digital health services, provides direct access to healthcare for patients, as well as globalization of production and distribution of medications. However, it is important to note that these activities can become illegal if e-commerce actors or involved institutions lack the necessary business permits and fail to comply with certification, licensing, registration, and other legal requirements. Aim: This article explores findings of illegal drug products within the context of online drug circulation through e-commerce. Method: The approach employed in this research is qualitative, utilizing descriptive analysis methods and data collection techniques through literature review. Result: It has been revealed that the sale of illegal drugs online occurs on the Marketplace through accounts using official pharmacy names. The illegal drugs and food products discovered do not adhere to good manufacturing standards and have unknown dosages. This poses a serious risk to public health if consumed. The identified types of illegal products include drugs specifically for men, illegal weight loss products, fake health supplements, illegal cosmetics, and counterfeit processed foods. Conclusion: The misuse of e-commerce platforms for the sale of illegal products must be taken seriously to safeguard the health and overall safety of the public. Keywords:  Illegal drugs, Online distribution, Supervision, Prevention, Legality
Deteksi Dini HIV (Human Immunodefeciency Virus) Menggunakan Metode Immunochromatography pada Remaja di Desa Bonto Bulaeng Kasratul Tiana; Rahmat Aryandi; Muriyati Muriyati
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 4 No. 2 (2023): PharmaCine : Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v4i2.11086

Abstract

Background: Human immunodeficiency virus (HIV) is a virus that weakens the human immune system, making people with the virus unable to fight various diseases that attack their bodies. Di sisi lain, Acquired Immunodeficiency Syndromes (AIDS) are symptoms that result from HIV infection that weakens the human immune system. Symptoms resulting from a weakening of the Human Immune System caused by HIV infection. The causes of Human Immunodeficiency Virus (HIV) are sexual intercourse, use of non-sterile syringes among drug users, use of piercings or tattoos, blood transfusions containing the HIV virus. Aim: The aim of the research is to determine the results of early detection of HIV (Human Immunodeficiency Virus) using the immunochromatography method in adolescents in BontoBulaeng Village. Method: This research method is descriptive research. This research was preceded by administering a questionnaire to obtain criteria in accordance with the research, HIV testing was carried out on adolescents using the immunochromatography method. This research began by giving questionnaires to respondents to obtain criteria that were appropriate to the research. Data analysis in this study used the SPSS frequency descriptive statistical test. Result: The results of this research were HIV tests on 30 teenagers, negative results were obtained (100%). Conclusion: Early detection of HIV using the immunochromatography method in adolescents in Bonto Bulaeng Village showed negative results for 30 samples (100%). Keywords: HIV, Teenager, Immunochromatografi
Pengaruh Sumber Asam Basa terhadap Sifat Fisik dalam Formulasi Granul Effervescent : Tinjauan Pustaka Reza Pratama; Ida Hasanah; Widya Nurasih; Novaliana Devianti Sagita
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 5 No. 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.11229

Abstract

Background: Indonesia has abundant natural resources, including types of herbal plants. Herbal plants in Indonesia have various health benefits and have been widely processed in the form of functional drinks. Aim:. To reduce the often undesirable taste and odor characteristics of herbal medicine, it can be further processed into derivative products that taste good and have a longer shelf life. One way is to process it into an effervescent preparation. Method: Searching and collecting journal information is carried out electronically, namely by accessing international and national journal search sites such as online from Pubmed, Google Scholar and Sciencedirect. by using the keywords "Effervescent Granules" and "Effervescent Herbal Drinks". Result: In effervescent granules there are acids and bases, the acids used are citric acid and tartaric acid which are acid components commonly used in effervescent granules. The use of a single acid will cause difficulties in its manufacture. The combination of citric acid and tartaric acid in effervescent granule preparations aims to simplify the process of making effervescent granule formulations. Conclusion: The results of existing literature studies show that the combination of acids in effervescent preparations greatly facilitates the process of forming effervescent granules. The use of different combinations of acid sources affects the physical properties of effervescent granules, including flow rate, dissolution time, pH and others. Sodium bicarbonate as a base source has the most significant influence on water content. The acid combination commonly used in making effervescent granules is citric acid and tartaric acid. Keywords: Effervescent granules, citric acid, tartaric acid, sodium bicarbonate
Minimalisasi Biaya Obat Antihipertensi Lisinopril Atau Candesartan Pada Pasien Hipertensi Disertai Gagal Ginjal Kronik Di Instalasi Rawat Inap RSUD Dr. H. Abdul Moeloek Anastya Devi Septiani; Putri Amelia Rooswita; Kiki Yuli Handayani
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 5 No. 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.11239

Abstract

Hypertension can damage blood vessels, which if not handled properly can cause kidney damage. Chronic Kidney Disease (CKD) is the most common comorbid in hypertensive patients in Indonesia with a percentage of 51%. The successful treatment of hypertension accompanied by CKD can be supported by administration of antihypertensives. The variety of antihypertensive therapy alternatives makes pharmacoeconomic studies necessary in order to obtain cost-effective therapy. The purpose of this study was to find out which antihypertensive drug is the most cost-minimizing between lisinopril and candesartan used in the treatment of hypertension accompanied by CKD (ICD-10 I12.0) in the Inpatient Installation based on the perspective of RSUD Dr. H. Abdul Moeloek in 2022. This research is a non-experimental observational with a purposive sampling technique. Data collection was carried out retrospectively from tracking secondary data originating from medical records, drug details in the Hospital Information System (SIRS), and details of direct medical costs in the Hospital Finance Department. Costs collected are in the form of direct medical costs which include antihypertensive drug costs, supporting drug costs, accompanying drug costs, laboratory costs, ICU, emergency room, hemodialysis, and hospitalization. The study showed that the average total cost of treating antihypertensive therapy for lisinopril was higher than candes artan, with lisinopril amounting to Rp 3.778.163 while candesartan was Rp 3.307.740. These results indicate that use of the antihypertensive candesartan is more cost-minimizing compared to lisinopril with a saving value of IDR Rp 470.423. Keywords: Pharmacoeconomics; CMA; hypertension with CKD; lisinopril; candesartan
Uji Kandungan Formalin pada Sampel Ikan Asin dan Ikan Segar yang Dijual di Pasar Tradisional Kiki Haetami; Lina Karlina; Junianto Junianto
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 5 No. 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.11339

Abstract

Background: Fish is a commodity that quickly deteriorates and spoils. One method commonly used to extend the shelf life of fish is by storing at low temperatures and salting. However, both methods are relatively expensive, so many sellers prefer to use formalin as a preservative for food products. Aim: This study aims to determine the use of formalin in salted fish and fresh fish in traditional markets. Methode: Testing was carried out qualitatively and quantitatively using the MERCK formalin test kit. Results: Test results on the formalin content of wais salted fish, skinned shark salted fish and salmon from the upper market of Cimahi obtained positive results in all three samples. Each formalin level is 0.10 mg/l; 0.80 mg/l; and 0.25 mg/l. Conclusion: The use of formalin in food products in traditional markets is still carried out by fish sellers. Keywords:  Formalin, Salted Fish, Fresh Fish, Traditional Market
Identifikasi Kandungan Bakteri Vibrio cholerae pada Produk Olahan Pepes Ikan Tuna (Thunnus sp.): Identification of the Bacterial Content of Vibrio cholerae On Tuna Fish Pepes (Thunnus sp.) Kiki Haetami; Inas Maya Tamimah Hanun
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 5 No. 2 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i2.12009

Abstract

Tuna (Thunnus sp.) is one of the potential fishery products because it has a high protein content. Tuna fish can be processed into various kinds of processing, one of which is pepes ikan which is a traditional Indonesia dish. Processed fishery products such as pepes can also experience a decrease in quality, one of which can be caused by the presence of bacteria, such as Vibrio cholerae bacteria. Vibrio cholerae is an opportunistic pathogen in estuarine and marine environments. These bacteria can be transferred into the food matrix causing illness if consumed by humans. The purpose of this study is to identify the content of Vibrio cholerae bacteria in tuna fish pepes processed products. The results of biochemical tests based on SNI 01-2332.4-2006 show that tuna fish pepes originating from one MSME in the Special Region of Yogyakarta does not contain or are negative for Vibrio cholerae so that it is suitable for marketing and human consumption. Keywords: Microbiology, Fishery Products, Processed Products, Tuna Fish, Vibrio cholerae.
Faktor Perilaku Yang Berhubungan dengan Kejadian Hipertensi di Puskesmas Serpong I, Kota Tangerang Selatan: Behavioral Factors Associated with the Incidence of Hypertension at Serpong I Primary Health Care, South Tangerang City Muhammad Nurul Raditya; Rony Darmawansyah Alnur
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 5 No. 2 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i2.12081

Abstract

Background: Hypertension is frequently regarded as a significant health concern. This is corroborated by the annual increase in hypertension cases. Behavioral factors, including smoking, physical activity, consumption of salty foods, and consumption of fatty foods, have been identified as risk factors for hypertension. Objective: The objective of this study is to examine the behavioral factors associated with the incidence of hypertension at the Serpong I Primary Health Care in South Tangerang City in 2024. Methods: The study employed a quantitative research design with a cross-sectional study structure and an analytic approach, utilizing the Chi-square test was conducted to examine the relationship between the independent variables and the incidence of hypertension. The study was conducted over a period of six months, from February to August 2024. The population under investigation in this study consisted of all individuals who visited the Serpong I Primary Health Care in South Tangerang City. The sample size for this study was 101 individuals, selected using the purposive sampling technique. The data were subjected to univariate and bivariate analyses. Results: The frequency distribution demonstrated that a greater proportion of respondents did not smoke (74, 73.3%), engaged in sufficient physical activity (72, 71.3%), consumed excessive amounts of salty foods (53, 52.5%), and consumed fatty foods (53, 52.5%). The results of the Chi-square test indicate that the variable most strongly associated with the incidence of hypertension (Pvalue <0.05) is the consumption of salty foods (P-value <0.001). While variables that are not associated (Pvalue > 0.05) include smoking (Pvalue = 0.661), physical activity (Pvalue = 0.173), and consumption of fatty foods (Pvalue = 0.079). Conclusion: The findings indicate a correlation between excessive sodium consumption and the prevalence of hypertension at the Serpong I Primary Health Care in South Tangerang in 2024. It is recommended that respondents to reduce the consumption of foods with high sodium content. Keywords: Hypertension; Risk Factors; Behavior;Primary Health Care.
Studi Kasus Peraturan Pemerintahan Republik Indonesia No.51 Tahun 2009 tentang Pekerjaan “Kefarmasian Apoteker di Jombang Diduga Langgar Kode Etik Kefarmasian”: Case Study of Government Regulation of The Republic Of Indonesia No.51 of 2009 Concerning Pharmaceutical Work “Pharmacist in Jombang Suspected of Violating Pharmaceutical Code of Ethics” Sophy Wulandari; Rima Putri Ramadhani; Muhammad Naufal Nurhadi Hidayat
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 5 No. 2 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i2.12235

Abstract

Bacakground: Pharmacists are health workers who have important responsibilities in drug management. However, there are still many violations of the code of ethics and lack of understanding of the regulations governing pharmaceutical practices, which can potentially endanger patients. Aim: This study aims to analyze the impact, sanctions, and legal protection related to the provision of expired drugs to patients. Method: The method in this research is qualitative descriptive analysis. The author collected data from various sources, including relevant regulations, case studies, and academic literature, to assess pharmacists' compliance with applicable pharmaceutical regulations. Results: Many pharmacists have not fully complied with existing regulations, especially in terms of drug management and storage. The findings also indicate the need for stricter law enforcement as well as increased training for pharmacists in understanding ethics and regulations. Conclusion: dispensing expired medicines has the potential to cause serious health impacts, including decreased drug efficacy and increased risk of side effects for patients. To address violations in the management of expired drugs, the relevant regulations provide for strict law enforcement as a sanction for violators, so as to encourage compliance with existing standards. In addition, legal protection for patients is stipulated in the law, which guarantees their right to obtain safe and quality medicines, in accordance with established quality standards. Keywords : Expired medication; pharmacy code of ethics; pharmaceutical work
Formulasi Pemanfaatan Ekstrak Daun Pepaya (Carica papaya L.) Sebagai Pestisida Nabati: Papaya Leaf Extract Utilization Formulation (Carica papaya L.) as a Pesticide Vegetable Sukmawati Sukmawati; Ameliawati Ameliawati
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 5 No. 2 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i2.12245

Abstract

Background: Many people do not understand how to use synthetic pesticides so that they can be harmful to humans. The use of pesticides made from nature can be a solution for the community, not only materials that are easily available but also ingredients that are safer because they use natural ingredients. Papaya leaves (Carica papaya L.) contain saponin and flavonoid compounds where these compounds can cause the death of pests.  Aim: This study aims to formulate it in pesticide preparations and then evaluate it so that it can be seen that the concentration of pesticide preparations is good  Method: This type of research is experimental in the laboratory by making 3 formulas consisting of F1 with a concentration of 8% papaya leaf extract, F2 12% and F3 16%. The tests include organoleptic, homogeneity and pH. Result: The results showed that the organoleptic tests carried out on all formulations did not have much difference, starting from the smell and shape they both had a liquid form, a distinctive smell of papaya leaves, only the concentrations from small to large experienced a brown to greenish-brown color. The homogeneity test results from the three formulations were not homogeneous and the pH test results were the more extracts, the higher the pH value. Conclusion:. Papaya leaf extract with concentrations of 8%, 12%, and 16% can be formulated in the form of pesticide preparations. Keywords: Excessive Synthetic Pesticides, Papaya Leaves (Carica papaya L.), Pesticides, Pests
Perbandingan Pertumbuhan Jamur Aspergillus fumigatus pada Media PDA (Potato Dextrose Agar) dengan Alternatif Media dari Tepung Sagu Rumbia (Metroxylon Sagu): COMPARISON OF THE GROWTH OF ASPERGILLUS FUMIGATUS MUSHROOMS ON PDA MEDIA (PotatoDextrose Agar) WITH ALTERNATIVE MEDIA FROM RUMBER SAGO FLOUR (Metroxylon sago) Asdinar Asdinar; Asrawati Asrawati; Adam Adam
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 5 No. 2 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i2.12333

Abstract

Background: Aspergillus fumigatus is a fungus that causes an opportunistic disease called Aspergillosis. Most tests used to determine the cause of fungal infections are carried out using the culture method. A popular growth medium for fungi is PDA media, which contains potato extract which is a source of carbohydrates. So that a substitute medium can be made that contains carbohydrates, sago flour is the highest carbohydrate producer, namely 84.7 grams per 100 grams of sago flour. Aim: To determine the comparison of the growth of Aspergillus fumigatus fungi on PDA media (potato dextrose agar) with alternative media from sago starch (Metroxylon sago). Method: This research methodology is pure experimentation with posttest only with control group design. Using the fungal culture method, with PDA media as control + and alternative media of sago starch sold at the Lambocca traditional market, Bantaeng, as test media with 3 concentration variants, namely concentrations of 12%, 14% and 16%. Result: Based on the findings of the research carried out, it can be concluded that five times the Aspergillus fumigatus treatment group was able to grow fungus which was grown in alternative media with concentration variants of 12%, 14%, 16%, and positive control. Conclusion: Media made from sago starch can be used as an alternative medium for growing Aspergillus fumigatus fungi. By looking at the average diameter of fungal colony growth at a concentration of 16% with an average of 10.85 mm, a concentration of 14% which is 9.3 mm and a concentration of 12% which is 7.5 mm. with the results of statistical tests, the p value = 0.000, which indicates there is a significant difference. Keywords: Aspergillus fumigatus, PDA, Sago flour

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