Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Articles
2,170 Documents
Factors influencing the survival of patients with end stage renal failure, who had been chronically hemodialyzed at Dr. Sardjito General Hospital.
Suhardi Suhardi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 04 (1995)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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An observational study on factors influencing the survival of 40 patients with end stage renal failure, who had been chronically hemodialyzed at Sardjito General Hospital was performed. The major causes of end stage renal failure in these patients were: chronic glomerulonephritis (22 patients); Diabetes mellitus (9 patients); renal stones (5 patients) and miscellaneous (4 patients). Seventeen of those 40 patients had poor protein intake (42,5%) while the other 23 patients had sufficient protein intake. Patients having sufficient protein intake proved to have better survival than those having poor ones who died more in the first year from intractable congestive heart failure with sepsis. Meanwhile other factors such as the control of hypertension, causes of end stage renal failure and the age of patients were not proved to influence the patients survival. Survival rates of the patients with end stage renal failure who had chronic hemodialysis at Sardjito General Hospital from 1 January 1986 to 31 December 1991 was 62.2% in the first year and 45% in the second year. Most patients died in the first year from intractable congestive heart failure with sepsis, and might becaused by poor protein intake,Key words : end stage renal failure - chronic hemodialysis - protein intake - survival rate.
The Evaluation of Vaginal Hysterectomy Using Spinal Anaesthesia
Ibnu Pranoto Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 39, No 02 (2007)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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Background. Vaginal hysterectomy can be performed on patient under general or spinal anesthesia. There are some advantages of spinal anesthesia compared to general anesthesia, although some prefer general anesthesia. We have done frequently vaginal hysterectomy using spinal anesthesia and we are reporting our experience.Objective:To know the spinal anethesia efficency compared to general anesthesia in terms of duration of vaginal hysterectomy operation, amount of bleeding and length of stay.Design: Cross sectional descriptive studySetting: Sardjito HospitalMaterials and methods: Patients underwent vaginal hysterectomy in Dr. Sardjito Hospital from March 2005 until February 2007Results: 50 patients underwent vaginal hysterectomy that consisted of 44 patients with spinal anesthesia and 6 patients with general anesthesia. Vaginal hysterectomy with spinal anesthesia had shorter duration of operation (1.93 hours) compared to general anesthesia (1.95 hours). Patients length of stay was shorter with spinal anesthesia (5.8 days) compared to general anesthesia (9 days). The average amount of blood loss in spinal anesthesia was (250.34 mil compared to general anesthesia (625.0 mil.Conclusion: This study suggests that spinal anesthesia reduces length of hospital stay and amount of blood loss in patients with vaginal hysterectomy compared to general anesthesiaKey Words: vaginal hysterectomy, spinal anesthesia, general anesthesia, duration of operation, amount of bleeding and length of stay.
The features of anaphylactic shock in Yogyakarta, Indonesia
R.H.Yudono R.H.Yudono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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An anaphylactic shock survey was carried out in Yogyakarta, Indonesia, during November December 1981. Physicians whith private practice were asked to complete the questionnaires given by the author. These questionnaires were collected without physician's identities.One hundred out of 135 respondents have had 270 patients suffering from anaphylactic shock accident. Two hundred and sixty one (96.7%) out of 270 patients had good recovery and 9 patients (3.3%) were dead. Preconditioning disturbances which made the therapy of these shocks difficult occurred in 27 patients (10 %).The drugs which caused these shocks were penicilline (27.8%). streptomycin (20%), penicilline streptomycin combination (14%), and others (38.2%). It was revealed that the route of administration of those drugs were intramuscular injection (97.4%), intravenous injection (1.1%), subcutaneous injection (1.1%). and oral administration (0.4%).Initial treatment of these shocks done by the physicians were intramuscular epinephrine (53%), intramuscular corticosteroid (23.7%), intramuscular antihistamine (15.9%), and intramuscular el-feud (1.5%). Two patients (0.7%) were immediately referred to the hospital without initial treatment given by the physicians. The rest (5.2%) had nonspecific treatment.Key Words: anaphylactic shock - allergen - penicillin - hypersensitivety - initial drug therapy
Proses Menjadi Tua (Proses Menua) Dilihat Dari Sudut Pahologi dan Immunologi
R. Moh Saleh R. Moh Saleh
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 7, No 03 (1975)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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Proses menjadi tua (proses menua) merupakan kejadian-kejadian faali (proses physiologis) yang dimulai sejak lahir dan diakhiri pada kematian, merupakan proses keausan (slijtage-proces).2. Orang-orang tua dianjurkan untuk menyadari keadaan tubuhnya, baik jasynaniah maupun rohaniah, sehingga mereka dapat menyesuaikan dini dan selanjutnya dapat hidup tenang, tenteram dan bahagia.
The first 24 hour bilirubin level as a predictor of hyperbilirubinemia in healthy term newborns.
Rina Triasih Rina Triasih
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 03 (2002)
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Background: The practice of early discharge in healthy term newborns results in difficulty for recognition, follow-up and early treatment of hyperbilirubinemia, the most common cause of readmission in term newborns.Objectives: The aim of the study was to determine the ability of first 24 hours total and unbound bilirubin levels in predicting hyperbilirubinemia in healthy term newborns in the first week of life. Methods: The first 24 hours and 5th day of total and unbound bilirubin were measured in 84 healthy term newborns. The total bilirubin level was measured spectrophotometrically whereas unbound bilirubin level was determined by peroxidase-oxidation method. Hyperbilirubinemia was defined as serum total bilirubin of a 12.9 mg/dL or serum unbound bilirubin of a 0.5 mg/dL after 24 hours of life.Results: A correlation between first 24 hours and 5th day of total bilirubin was found (r= 0.53) with a regression equation: Y (total bilirubin day 5) = 4.69 + 1.15 X (total bilirubin first 24 hours). In unbound bilirubin (r= 0.31), the regression equation was Y (unbound bilirubin day 5) = 0.13 + 0.95 X (unbound bilirubin first 24 hours). The relative risk of newborns whose first 24 hours total bilirubin of a 4.5 mg/dL and becoming hyperbilirubinemia was 12 (95% CI = 2.9 - 48.4), and newborns whose unbound bilirubin of a 0.09 mg/dL was 9.5 (95% CI = 1.2-77.4).Conclusions: Total bilirubin level a 4.5 mg/dL in the first 24 hours can predict the occurance of hyperbilirubinemia in the first week of life inthe term newborns.Key word: fullterm newborn, hyperbilirubinemia, prediction, total bilirubin, unbound bilirubin
The difference in perception on the importance of sex education for adolescence between elderly and adolescence
Soewadi Soewadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 31, No 01 (1999)
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Background: Sexual life is important in the life of a person, i:e. the interaction between male and female. An adequate knowledge of sex helps one to avoid a variety of problems in living, helps prevent sexual dysfunctions among other disorders, adds enjoyment of sex itself, and probably enhances life in numerous other ways. However, modern societies restrict and control the sexual behavior and expression of the young, so that the sex instinct does not prepare young person for a successful sex life.Objective: To identify the difference in perception of the importance of sex education among adolescence between elderly and adolescence.Subjects: The study was carried out in Yogyakarta among elderly (retired person) and adolescence (students in the first year of their undergraduate study).Methods: The study was undertaken using structured questionnaires distributed to subjects selected using simple random sampling.Study design: cross-sectional survey. Statistical analysis: Chi-square technique.Results: The results showed that there was a significant difference between the group of elderly subjects and adolescence according to the perception of the importance of the sex education among adolescence (p<0.05).Conclusions: there is a relationship between age and the perception on the importance of sex education for adolescence.Key words: sexual education - elderly - adolescence
Hiperglikemia dan Komplikasi Akut Diabetes Mellitus
Ahmad H Asdie Ahmad H Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 19, No 03 (1987)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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Diabetes mellitus is a chronic metabolic disorder due to relative or absolute deficiency of insulin. The disease may be characterized by acute symptoms and signs of insulin deficiency, which are called acute complications in this paper. Diabetes is also associated with chronic complications such as atherosclerosis, neuropathy, nephropathy, retinopathy, and' cataract. The paper presented a brief review of the role of hyperglycemia in the development of complic ations in the diabetic patient. There is little controversy as to the necessity of insulin for therapy and for prevention of diabetic complications. Key Words: diabetes mellitus - insulin deficiency - hyperglycemia - metabolic disorder - lipoprotein
Molekul Major Histocompatibility Complex (MHC) Klas II pada Epitel Usus: Presentasi Antigen Luminal?
Y. Andwi Ari S Y. Andwi Ari S
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 26, No 03 (1994)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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The major histocompatibility complex (MHC) class II antigens were originally described to be expressed on the surface of B lymphocytes, macrophages, skin Langerhans cells (LC) and dendritic cells (DC). Surprisingly, the class Il molecules of MHC are also found in the intestinal epithelium.The distribution and expression of la molecules on intestinal epithelial cells depend on the continuous exposure of antigen and the presence of certain stimuli, like interferon-gamma, inflammation process in the gut and graft-versus-host disease. The function of class II molecules on intestinal epitheliurn may be different from those molecules on 'professional' antigen presenting cells. Luminal antigens which are processed by enterocytes will be delivered to CD8 cells in the vinous epithelium and led to immunosuppression, whereas antigen uptake by M cells in the Peyer's patches will be presented to CD4 cell populations, and initiate the immune response.Key Words : antigen processing-MHC molecule-enterocytes-Peyer's patches-mucosal immunity
Effect of swimming and asthmatic exercise on forced expiratory volume in 1 second (FEV1) and levels of cortisol hormone in asthmatics patients
Rahmaya Nova Handayani, Denny Agustiningsih Achmad Djunaedi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 01 (2012)
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Bronchial asthma is one of the allergic diseases characterized by reversible bronchial narrowing dueto bronchial hyperactivity and obstruction of respiratory tract. The prevalence and hospitalizationrates of bronchial asthma keep increasing from year to year, causing asthma to be the top ten causesof morbidity and mortality in Indonesia. The decrease of the forced expiratory volume in 1 second(FEV1) is one of the indicators of the respiratory tract obstruction. Moreover, the cortisol hormonelevel is also associated with asthma. Asthma can be treated not only with pharmacological interventionbut also physical exercises. The aim of the study was to assess the increase of FEV1 and cortisolhormone level after swimming and asthmatic exercise on asthmatic patients. This was a quasiexperimental study using pre and post test control group design. Two groups of 10 asthmaticpatients each conducted swimming and asthmatic exercise as intervention. On pre, middle and postswimming or asthmatic exercise, those two groups underwent the measurement of FEV1 using aspirometer and cortisol hormone levels using ELISA methods. The result showed that the value ofFEV1 and cortisol hormone levels increased significantly after swimming and asthmatic exercise(p<0.05). Moreover, the improvement of FEV1 value and cortisol hormone levels of asthmaticpatients in swimming were higher than asthmatic exercise. In conclusion, swimming and asthmaticexercise can increase the value of FEV1 and the levels of the cortisol hormone.Keywords : swimming - asthmatic exercise - FEV1 - cortisol hormone - asthma