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INDONESIA
e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 621 Documents
Pengaruh Pemberian Ekstrak Propolis Terhadap Kadar Kolesterol Darah Tikus Wistar Jantan Setelah Dipapar Sidestream Cigarette Smoke (Effect of Propolis Extract on Blood Cholesterol Level in Male Wistar Rats After Being Exposed to Sidestream Cigarette Smoke Chusna Sekar Wardani; Roedy Budirahardjo; Budi Yuwono
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Smoking is one of environment factors which caused a bad effect for health. TheSidestream Cigarette Smoke (SCS) contained in smoke produce free radicals highly andincrease total cholesterol levels. Elevated levels of total cholesterol can be treated withmedicine of statins, but its use in the long term cause side effects. Therefore, at thistime medicine has been developed from natural a substance which is expected haveless side effects, one of which is propolis. This research aims to determine whether thereis a decrease in total cholesterol levels in male Wistar rats (Rattus norvegicus) whichwas given extracts of propolis and exposed SCS. The research is experimentallaboratory with post test control group design. This research uses 12 rats which consistof 2 groups (1 control and 2 groups of treatment). The first treatment group is exposedby SCS. The second one is exposed by SCS and given the extract of propolis 2 times aday for 8 days. The total blood cholesterol level is measured by usingspectrophotometer with enzymatic colorimetric methods. The results of data analysisusing One Way Anova test shows there is a significant difference in total bloodcholesterol level means of male Wistar rats (p <0.05). While the Tukey HSD test showsthere is a significant difference in total cholesterol level means between groups, exceptbetween the control group and the second treatment group. Conclusion of thisresearch is that the propolis extract can lower total cholesterol levels of male Wistar ratswhich given exposure of Sidestream Cigarette Smoke.Keywords: blood cholesterol levels, propolis extract, sidestream cigarette smoke
Perbedaan Kekuatan Tarik Bahan Adhesif Total-Etchdengan Bahan Adhesif Self-Etchpada BondingBraket Ortodonsi (The Difference of Tensile Strength Between Total-Etch Adhesive Material and Self-Etch Adhesive Material for Orthodontic Bracket Bonding) Dita Nur Ekasari; Herniyati .; Dwi Prijatmoko
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background.Orthodontic treatment using a bracket attached to the teeth dentofasial aiming to get a good look aesthetically. At the beginning of orthodontic bracket bonding systems to enamel surface through several stages of work so that they can spend time, includes teeth cleaning, basting phosphoric acid etching, washing with water, drying, basting material bonding / primer, and application of composite resin as a bracket adhesive material called total-etch technique. But as the times have found self-etch adhesive that further simplify the time and phases of work, the incorporation of phosphoric acid etching and bonding materials / primer in one package. Tensile strength is the strong adhesive tensile or the ability of an object to hold while receiving an attractive force and the force coming from the direction perpendicular to the surface of the object, for example when there is an attractive force toward the labial or buccal tooth driven. Purpose. This study aimed to determine differences in tensile strength and know the best adhesive that can be used between total-etch adhesive with a self-etch adhesive on orthodontic bracket bonding. Methods.This study used 16 pieces mandibular firstpremolars were divided into two groups, each consisting of eight teeth. The first group used a total-etch adhesive, while the latter uses self-etch adhesive. Bracket adhesive tensile strength was measured using Torsee's Digital System Universal Testing Machine. Results.Independent t-test showed a significant difference between groups in total-etch adhesive with a self-etch adhesive (p <0.05). Conclusions and suggestions.There is a significant difference in tensile strength measurements of total-etch adhesive with adhesive and self-etch adhesive total-etch proved better than a self-etch adhesive on orthodontic bracket bonding. Further research needs to be done with respect to the composite resin material used, the stages of research, and tools used tensiletest. Keywords:bonding, self-etch adhesive, tensile strength, total-etch adhesive
Hubungan Pelaksanaan Peran Keluarga dengan Kejadian Stunting pada Balita di Kecamatan Arjasa, Jember Umari Hasniah Rahmawati; Latifa Aini S; Hanny Rasni
Pustaka Kesehatan Vol 7 No 2 (2019): Volume 7 No. 2, 2019
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v7i2.19123

Abstract

A family has an important role to meet the nutritional intake of toddlers since a family has a full decision to nurture and take care of the toddlers. However, the case of stunting in Jember Regency still has a higher case compared to other regencies. The objective of this research was to analyze the relationship between the implementation of family role and the case of stunting in toddlers in Arjasa Subdistrict, Jember regency. The research also used a cross sectional research design with cluster random sampling technique. The data collection was conducted by providing a FAD (Family Assessment Device) questionnaire used to identify the family roles, while the height was measured by length board and microtoise. The chi-square test was employed to analyze between the variables of family role and stunting case. According to the analysis result of 117 respondents, there were 7.7%, 99% and 7.7% for each category of good, moderate and less in the family role, whereas for the stunting case, there were 76.1% having stunting and 23.9% not stunting. The findings of this research indicated that there was a relationship between the implementation of family role and the stunting case (χ2 = 9.78; p-value = 0.002), in which the implementation of family role in the good category had 7.81 times for a chance of stunting (OR = 7.81; 95% CI = 1.81-33.762). at last, this research showed the importance of improving the family role by involving the family to meet the daily nutritional intake of toddlers so as the stunting case can diminish.
Efektivitas Chlorhexidine sebagai Inhibitor MMP-2 dan MMP-9 dalam Proses Dermonekrosis Akibat Racun Kumbang Tomcat (Paederus sp.) (The Effectiveness of Chlorhexidine as MMP-2 and MMP-9 inhibitor in Dermonecrotic Process due to Rove Beetles Toxin (Paederus sp.)) Putri Erlinda Kusumaningarum; Al Munawir
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Paederus dermatitis is dermonecrotic condition caused by Rove beetles (Paederus sp.). Paederin toxin come from endosymbiotic between rove beetles and Pseudomonas aeruginosa and can produces MMP-2 and MMP-9. Chlorhexidine is expected to be alternative therapy and prevention of dermatitis paederus due to it's MMP inhibitor and bacteriostatic effect. The study aimed to investigated the effectivity of chlorhexidine as MMP-2 and MMP-9 inhibitor in dermonecrotic process due to rove beetles toxin. Research groups consisted of negative control (paederin toxin), treatment 1 (paederin toxin + chlorhexidine 0,012%), treatment 2 (paederin toxin + chlorhexidine 0,06%), treatment 3 (paederin toxin + chlorhexidine 0,3%), and normal control (aquadest). As much as 9,3 µg paederin toxin and chlorhexidine are injected to the well of 8% acrylamide gel containing gelatin. Measuring of band density using ImageJ showed a decreasing of MMP-2 and MMP-9 band density. Negative control group was considered to have 1 of relative optical density. The result showed that chlorhexidine 0,06% can inhibits 21,6% MMP-2 activities and at 0,3% can inhibits 16,4% MMP-9 activities. One way ANOVA test show different significantly between negative control and treatment group (p<0,05). In conclusion chlorhexidine has potency as MMP-2 and MMP-9 inhibitor in dermonecrotic process due to Rove Beetles toxin. Keywords: Rove beetles(Paederus sp.), dermonrcrotic, MMP-2, MMP-9, chlorhexidine
Terapi Nutritif Modifikasi Modisco Menggunakan Ekstrak Nanas Meningkatkan Hemoglobin pada Tikus Wistar KEP Berat Alfi Kamalia; Erma Sulistyaningsih; Sugiyanta Sugiyanta
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

The data from the Health Research Association of Indonesian Ministry of Health in 2010 showed approximately 35.6% infants having PEM. The diet therapy for severe PEM is modisco. However, due to protein deficiency such as a protease enzyme resulting in nutrients malabsorption, modisco has not been able to compensate the lack of protein in PEM. It requires an active substance to increase protein absorption by adding a proteolytic enzyme. One of the source of proteolytic enzyme is pineapple. The study aimed to prove that addition of pineapple extract on modisco can increase levels of albumin and hemoglobin in severe PEM rats. This was a true experimental study with pre-post test control group design. The sample were 25 male Wistar rats aged 2 months. The data analysis using the Pairwise T test, one way ANOVA followed by LSD showed a significantly difference between pre and post test for both albumin and haemoglobin. The pineapple extract at a dose of 9 and 11 mg/day increased albumin level. And the dose of 7, 9 and 11 mg/day pineapple extract increase haemoglobin level. In conclusion, a modisco modification using pineapple extract for nutritive therapy increased both albumin and hemoglobin levels on severe MEP rats.   Keywords: Severe PEM, Modisco, Pineapple extract
Optimasi Propilen Glikol dan Etanol sebagai Peningkat Penetrasi Ibuprofen dalam Sediaan Gel dengan Metode Simplex Lattice Design (Propylene Glycol and Ethanol Optimization as Ibuprofen Penetration Enhancer in Gel Dosage using Simplex Lattice Design Metho Baiq Wahyudyati Karnia Qisti; Dwi Nurahmanto; Viddy Agustian Rosyidi
Pustaka Kesehatan Vol 6 No 1 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i1.6611

Abstract

Ibuprofen is a non-steroid anti inflammatory drug (NSAID) used for rheumatoid arthritis treatment. In this study, formulation, evaluation, and optimization of ibuprofen gel formula were conducted in order to determine the best ibuprofen penetration rate through the rats skin using propylene glycol and ethanol as penetration enhancers and to find out the optimum formula to get the best penetration rate with simplex lattice design method. Evaluations included organoleptic, pH, viscosity, gel dispersive, assay of gel formulations, and ibuprofen penetration rate assay. Penetration rate was determined by paddle type dissolution and the samples were analyzed by spectrophotometry UV-Vis. The results of ibuprofen penetration rate assay were analyzed and optimized using design expert trial version 10. The results of ibuprofen penetration rate were F1 1.524 ± 0.121 µg/cm2.minute; F2 1.945 ± 0.0104 µg/cm2.minute; and F3 1.173 ± 0.216 µg/cm2.minute. Penetration rate optimization resulted in one optimum solution formula which was 18.000% propylene glycol and 12.000% ethanol with a maximum flux of 1.957 ug/cm2.minute and desirability 1. It can be concluded that the best ibuprofen penetration rate was F2 with flux 1.945 ± 0.0104 µg/cm2.minute with 15% propylene glycol and 15% ethanol. Keywords: gel, ibuprofen, propylene glycol, ethanol, simplex lattice design
Faktor-faktor yang Mempengaruhi Kejadian Stunting pada Anak Balita di Wilayah Pedesaan dan Perkotaan (The Factors Affecting Stunting on Toddlers in Rural and Urban Areas) Farah Okky Aridiyah; Ninna Rohmawati; Mury Ririanty
Pustaka Kesehatan Vol 3 No 1 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

In 2013, the prevalence of stunting in rural areas of Jember is 67% and 27,27% for urban areas. Stunting if problem above 20% that is a public health problem. The purpose of this study was to analyze the factors that influence the genesis of stunting in toddlers between rural and urban areas. This type of this study is an observasional analytic with cross-sectional approached and conducted in Patrang health center and Mangli health center for urban whereas Kalisat health centers for rural with sample fifty respondents each. Analysis of data consisting of chi-square test, mann whitney test and logistic regression with α=0,05. Result of analysis showed that affecting factors of stunting occurrence in toddlers who are in the rural and urban areas were the mother's education, family income, mother's knowledge of nutrition, exclusive breastfeeding, complementary feeding age provision, zinc and iron adequacy level, infection disease history and genetic factors. However, another factors such as mother's work, family numbers, immunization status, energy adequacy level and BBLR status didn't affect the occurrence of stunting. Protein and calcium adequacy level in rural areas showed a significant relation while in urban areas showed no relation. The most factor affecting stunting on toddlers in rural and urban areas was zinc adequacy level. Keyword: Stunting, Toddlers, Rural, Urban
Pelaksanaan Wajib Notifikasi (WiFi) TB di Dinas Kesehatan Kabupaten Jember Fiya Wadudah; Irma Prasetyowati; Candra Bumi
Pustaka Kesehatan Vol 8 No 2 (2020): Volume 8 No. 2, 2020
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v8i2.20360

Abstract

Indonesia mengikuti target eliminasi global yaitu Eliminasi TB 2035 dan Indonesia bebas TB 2050. Tantangan dalam program pengendalian Tuberkulosis di Indonesia adalah banyaknya kasus tuberkulosis yang tidak terdeteksi maupun kasus yang sudah terdeteksi namun belum terlaporkan, sehingga perlu dilakukan perubahan pendekatan penemuan kasus, dari secara pasif menjadi intensif dan aktif. Rumitnya pengisian form TB oleh dokter swasta, membuat rendahnya notifikasi pasien TB. Maka dibuat aplikasi berbasis smartphone yaitu Aplikasi Wajib Notifikasi TB (WiFi) TB yang lebih sederhana dan mudah digunakan. Penelitian ini bertujuan untuk menggambarkan pelaksanaan wajib noifikasi (WiFi) TB di Dinas Kesehatan Kabupaten Jember. Penelitian ini menggunakan jenis penelitian deskriptif. Sampel penelitian adalah 2 petugas TB. Penelitian ini dianalisis menggunakan analisis deskriptif. Hasil dari penelitian ini menunjukkan bahwa gambaran dari aspek input, proses, dan output dalam pelaksanaan wajib notifikasi (WiFi) TB
Prevalensi Indikasi Perawatan Tumpatan pada Pasien yang Berkunjung ke RSGM Universitas Jember Tahun 2015 (The Indication Prevalence of Restoration Treatments in Patients Who Attended Dental Hospital University of Jember in 2015) Ilonavia Satiti; Dwi Warna Aju Fatmawati; Sri Lestari
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Introduction:Teeth are hard tissue that serve as the process of mastication in humans. In the event of tooth damages, they can not perform their functions optimally. Dental hard tissue damages include caries, attrition, abrasion, erosion and fracture.The damage of tooth hard tissues can change the anatomical shape of the tooth which make them fail to function properly. Restoring the damaged anatomical shape can be achieved by restoration or fillings.Objective: To know the indication of restoration treatments in patients who attended RSGM University of Jember in 2015.Methods:This research was a descriptive study with Cross Sectional Study approach. The study was conducted at RSGM University of Jember. The number of respondents were 100 which was obtained by using the Slovin formula.Result and Conclusion: The prevalence of restoration treatments indication in patient who attended RSGM University of Jember in 2015 was 89% . It was distributed based on sex was 52,8% for women and 47,2% for men, based on age groups, 21-26 year-old-group had the highest prevalence, while 33-44 year-old-group had the lowest prevalence.  Keywords: restoration treatments, prevalence
Pengaruh Pemberian Galaktomanan dari Daging Kelapa Lokal (Cocos nufitera L) terhadap Kadar Glucagon Like Peptide-1 (GLP-1) pada Tikus Wistar Jantan yang Hiperkolesterolemia Inayatul Aulia; Achmad Subagio; Aris Prasetyo
Pustaka Kesehatan Vol 2 No 2 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Hypercholesterolemia is a condition characterized by high cholesterol concentration in blood. This is a risk factor for many diseases. Glucagon Like Peptide-1 (GLP-1) is an incretin hormone that affects cholesterol and other diseases with hypercholesterolemia as a risk factor. Drug that widely used for hypercholesterolemia is simvastatin which can increase GLP-1. GLP-1 also can be increased by high fibrous foods consumption, one of which is galactomannan which can be found in coconut as much as 61%. This study aimed to determine the effect of galactomannan on GLP-1 and compared with simvastatin. Wistar rats were induced into hypercholesterolemia and than treated with galactomannan 70 mg/200gBW/day and 140 mg/200gBW/day and simvastatin 0,1 mg/200gBW/day. After 28 days, GLP-1 levels was measured. The result showed that GLP-1 in 140 mg/200gBW/day group was the highest and in 70 mg/200gBW/day group was the lowest. Data analysis revealed no significant difference between 140 mg/200gBW/day and simvastatin group. In conclusion, galactomannan 140 mg/200gBW/day had the same potency as simvastatin 0,1 mg/200gBW/day.   Keywords: Hypercholesterolemia, GLP-1, Galactomannan, Simvastatin