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Erma Sulistyaningsih
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Kab. jember,
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INDONESIA
e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 621 Documents
Optimasi Formula Tablet Effervescent Dispersi Padat Meloksikam Menggunakan Desain Faktorial Lusia Oktora Ruma Kumala Sari; Tiara Berlianti; Eka Deddy Irawan
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7571

Abstract

An effervescent tablet of meloxicam solid dispersion has been developed for geriatric patients who have difficulty swallowing. The objective of this research was to know the optimum concentration of citric acid and sodium bicarbonate which produce the best effervescent tablet. A 2² factorial design was applied to investigate the effect of two factors: concentration of citric acid and sodium bicarbonate (effervescent materials) on hardness, dissolve time, and %drug released t30. Citric acid (6-18 mg) was used as acid source and sodium bicarbonate (18-105 mg) was used as base source. Software Design Expert trial version 10.0.5. was used to determine the optimum formula. The result showed that all formula satisfied the limit of hardness 2-4 kg/cm2 and friability <1%, but only formula (1), b, and ab that satisfied the limit of dissolve time <300 sec and %drug release t30 >70%. Formula A showed dissolve time 436 sec and %drug release t30 less than 70%. Desirability value of 0.917, which indicated the optimum formula, was obtained from the use of citric acid 6 mg and sodium bicarbonate 105 mg. Keywords: meloxicam, effervescent tablet, solid dispersion, factorial design
Analisis Faktor Individu, Faktor Organisasi dan Kelelahan Kerja Terhadap Stres Kerja Pada Perawat (Studi di Ruang Rawat Inap Kelas III RSU dr. H. Koesnadi Kabupaten Bondowoso) (Analysis of Individual Factors, Organization Factor and Occupational Fatigue W Ekin Akhsa Febriandini; Isa Ma`rufi; Ragil Ismi Hartanti
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Hospital is a health service place. The service claims can create some danger like work stress. Based on the preliminary studies that has been done at General Hospital dr.H Koesnadi, Bondowoso district , found that 67 % nurses experienced the occupational fatigue and work stress. The work stress is influenced by some factors like individual factors (gender, age, length of service and level of education), organization factor like work shift and occupational fatigue in the hospital's employee. Human resource has potential about the work stress of nurse in handly the patient directly. The purpose of this research is to analyze the relation between individual factors, organization factor and occupational fatigue in the work stress. The method that used in this research is analytical observation with the cross sectional design. The sampel of this research is 46 respondents that spread over 5 inpatient room 3rd grade.The result of this research showed that there was a significant relation between individual factors and work stress (p = 0,004), the relation between the organization factor and the work stress (p = 0,038). It is also known that there was a relation between occupational fatigue with the work stress (p = 0,047) Keywords: Individual Factors, Organization Factors, Occupatiunal Fatigue, Work Stress
Hubungan Indeks Kepuasan Pasien tentang Mutu Pelayanan Dimensi Jaminan dengan Minat Berobat Kembali di Poli Interna RSD Kalisat Jember (The Relationship between Patient’s Satisfaction Index on Assurance of Service Quality and Utility at Internal Medicine Zuliyatul Masnunah; Dwita Aryadina Rachmawati; Sugiyanta Sugiyanta
Pustaka Kesehatan Vol 5 No 2 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

The increasing number of hospitals causes competition among hospitals to get patients so that each hospital must provide quality services to reach patient’s satisfaction. Patient’s satisfaction determines patients behavior in the future, include their interest in utility. The purpose of this study was to find out the relationship between patient satisfaction index on assurance of service quality and utility. This study used cross-sectional design with 50 respondents. Patient’s satisfaction index and utility were measured using ServQual questionnaire. The results of statistic test with Spearman's Rho correlation test showed that the significance (p) = 0,030 with correlation coefficients (r) = 0.308. So, it can be concluded that there was a weak relationship between patient’s satisfaction index about assurance of service quality and utility at Interna Medicine Polyclinic Kalisat Hospital Jember. Keywords: Patient’s satisfaction, service quality, assurance, utility.
Deteksi Protein 270 kDa Plasmodium falciparum Isolat Malang pada Membran Eritrosit Penderita Malaria dengan Komplikasi Dewi Indiastari; Sri Winarsih; Loeki Enggar Fitri
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7785

Abstract

Erythrocyte which is infected by Plasmodium falciparum will have various changes on its architecture, affinity, and biomolecular. Beside that, the infected erythrocyte also forms a knob at its surface. This knob are contained with various parasite proteins, one of them is Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP-1). Our previous study had been identified a protein with molecular weight 270 kDa at P. falciparum infected erythrocyte from Malang isolate that was playing a role in cytoadherence process. The aim of this study was to detect the possibility of 270 kDa protein expression at complicated malaria falciparum patient erythrocyte membrane. The method that used was immunocytochemistry with polyclonal antibody to 270 kDa protein. The results showed that two (2) erythrocyte samples from healthy people as control had negative reaction, and so did with five (5) erythrocyte samples of uncomplicated malaria patient, but there was positive reaction that shown at two (2) samples of complicated malaria patient erythrocyte. It can be concluded from the results that 270 kDa membrane protein of P. falciparum infected erythrocyte in complicated malaria patient might be a PfEMP-1. This protein can be detected by immunocytochemistry method using polyclonal antibody and can be used for the candidate of complicated malaria diagnostic Keywords: Plasmodium falciparum, 270 kDA protein, immunocytochemistry, polyclonal antibody
Pengaruh Pemberian Gel Doksisiklin terhadap Jumlah Fibroblas pada Proses Penyembuhan Dermatitis Paederus akibat Racun Kumbang Tomcat (Paederus sp.) pada Mencit (The Effect of Doxycycline Gel on The Number of Fibroblast in Paederus Dermatitis Healing Silvi Ahmada Chasya; Al Munawir; Erma Sulistyaningsih
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Paederus dermatitis caused by rove beetle makes the tissue damage called dermonecrosis. The MMP on pederin toxins from the symbiosis of rove beetle (Paederus sp.) and Pseudomonas aeruginosa is supposed can delay the wound healing process. Doxycycline gel as a MMP inhibitor is believed can accelerate the healing process. The purpose of this study was to determine the effect of doxycycline gel on the healing process of Paederus dermatitis by observing the number of fibroblasts as an indicator. This study used 40 mice, were divided into four major groups, those were normal control group, the negative control, treatment groups with doxycycline gel 1% and 5%. Termination was performed on days 1, 3, 5, 7, and 15. Data was obtained by calculating the number of fibroblasts per field of view, then processed in ImageJ and tested statistically with comparation test of One Way Anova. The average number of fibroblasts per field of view in treatment groups was higher. The peak occurred on day 7 and decrease on day 15. It indicated that the topical administration of doxycycline gel on Paederus dermatitis can accelerate healing process, showed by the increasing in average number of fibroblasts per field of view. Keywords: doxycycline gel, fibroblast, paederus dermatitis
Identifikasi Drug Related Problems (DRPs) pada Terapi Diabetes Melitus Tipe 2 di Instalasi Rawat Inap RSD dr. Soebandi Jember Periode Tahun 2015 (Identification of Drug Related Problems (DRPs) for Type 2 Diabetes Mellitus Therapy in Hospitalized Patients Khoirotun Nazilah; Ema Rachmawati; Prihwanto Budi Subagijo
Pustaka Kesehatan Vol 5 No 3 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i3.5891

Abstract

Diabetes mellitus (DM) is a degenerative disease which causes various complications that require patients to use polypharmacy. The use of polypharmacy has been reported to be one of the causes of drug related problems (DRPs). DRPs are unexpected events related to the treatment undergone by the patient. This study aimed to avoid DRPs so that patients could receive the best treatment. This research used total sampling method and conducted retrospectively using medical records of patients with type 2 diabetes which were hospitalized in RSD dr. Soebandi Jember in 2015. As many as 15 patients (25%) of 60 patients experiencing DRPs were included in the six criteria of DRPs. This criteria included unnecessary drug therapy found in 1 patient (6,67%), need for additional drug therapy found in 1 patient (6.67%), ineffective drug found in 4 patients (26,67%) and drug interactions found in 10 patients (66.67%). Eventhough too high dosage and too low dosage was not found in all patient samples. Keywords: type 2 diabetes mellitus, drug related problems (DRPs), antidiabetic, hospitalized
Pengaruh Ekstrak Metanol, Fraksi N-Heksana dan Fraksi Metanol Biji Pepaya (Carica papaya L.) terhadap Motilitas Spermatozoa Tikus (Effect of the Methanol Extract, Hexane Fraction and Methanol Fraction of Papaya Seeds (Carica papaya L.) on Rat Spermato Novi Prasetyaningrum; Siti Muslichah; Moch Amrun Hidayat
Pustaka Kesehatan Vol 3 No 1 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Lack of contraceptive choices which meet the requirements is one of the contributing factors to less participation of man in contraceptive use. This research aimed to study the effectiveness of papaya seeds on rat spermatozoa motility. The rats were separated into 4 groups: negative control group (CMC-Na 1%), methanol extract of papaya seeds (100 mg/kg BW) treatment group, n-hexane fraction of papaya seeds (100 mg/kg BW) treatment group, and methanol fraction of papaya seeds (100 mg/kg BW) treatment group. Each treatment group consisted of 5 rats. Each group was administrated orally for 20 days. On 21st day, the rats were sacrified, the spermaatozoa were and were observed on their motility. The data then was anallyzed using Anova followed with LSD. The sperms which moved progressively in negative control, methanol extract, n-hexane fraction and methanol fraction were 67.6%, 29.8%, 38% and 10.6% respectively the methanol fraction of papaya seeds is more potent in reducing sperm motility. Keywords: antifertility, papaya seeds, spermatozoa motility
Hubungan Sanitasi Lingkungan dengan Kejadian Infeksi Soil Transmitted Helminths pada Anak Sekolah Dasar di Jember Nur Aqmarina Kusumawardani; Erma Sulistyaningsih; Cicih Komariah
Pustaka Kesehatan Vol 7 No 1 (2019): Volume 7 No. 1, 2019
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v7i1.17591

Abstract

Poor environmental sanitation is suspected to be one of the causes of soil transmitted helminthes (STH) infection. Environmental sanitation consists of water sources, latrine, sewerage, garbage disposal facilities, and floor type. The objective of this study was to investigate the relationship between environmental sanitation and the incidence of STH infection in primary school children. This was an observational analytic study with cross-sectional design. The subjects were 80 students of two elementary schools in Jember. Stool samples were collected and examined by Kato-Katz method. Data of environmental sanitation was collected by questionnaire and direct observation. Kato-Katz examination showed that 9 samples (11,3%) infected by Ascaris lumbricoides. The majority respondents had not fulfilled requirements of good environmental sanitation. The result of Spearman test showed that there was a significant correlation between STH infection and latrine (p=0,02) but there were no significant relationship between STH infection and environmental sanitation (p = 0.165), gender (p = 0,669), age (p = 0,92), water source (p = 0.084), sewerage (p = 0.146), garbage disposal facilities (p = 0,728), and floor type (p = 0,065).
Hubungan Motivasi Perawat dengan Pelaksanaan Prinsip 12 Benar dalam Pemberian Obat di Ruang Rawat Inap RSU dr. H. Koesnadi Bondowoso (The Correlation between Nurses’ Motivation with the Implementation of 12 Principles of Right in Medicine Giving in Inpat Retno Utami; Dodi Wijaya; Iis Rahmawati
Pustaka Kesehatan Vol 3 No 3 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Nurse is the most appropriate medical staff to give medicine and vacate their time for the patients. In giving medicine, nurse also must concern on the given prescription must be appropriate, the exact qualification of dosis that is given and always applying 12 principles right away. This condition might cause the occurrence of interaction between the characteristic of a nurse that is her motivation and his work. The purpose of the research is to analyze the relation of nurse’s motivation and applied of 12 principles of right in giving medicine in inpatient wards of dr. H. Koesnadi hospital in Bondowoso. The design of this research that is used is observational analysis with cross sectional and sample approach used 51 correspondences. Data collection technique is sample probability with simply random sampling. The result of the data analysis used chi square test. The result show that P value 0.005 (0.005< α=0.05) means that there is relation between nurse’s motivation and the applies 12 principles of right in giving medicines having this research, hopefully for the institution of the hospital for increase even more the nurse’s motivation in working by giving reward and punishment to the nurses and give them special seminar related to 12 principles of right in giving medicines.   Keywords: nurse’s motivation, 12 principles of right in giving medicines, inpatient wards
Pengaruh Teknik Desinfeksi dengan Berbagai Macam Larutan Desinfektan pada Hasil Cetakan Alginat terhadap Stabilitas Dimensional Distrina Fitrian Sari; R. Rahadyan Parnaadji; Agus Sumono
Pustaka Kesehatan Vol 1 No 1 (2013)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

A Impression material that is often used is alginate. Alginate has Characters imbibition and syneresis properties that can cause dimensional changes alginate mold result. Another factor to consider is the control of transmission of infection from alginate, as alginate mold result became one of the agents of transmission of infection in the dentist, it is important to take action disinfection with a disinfectant solution. Type of laboratory experimental research with the study design The Post Test Control Group Design on 72 samples of alginate mold. Sample grouping consists of 9 groups , 1 control group and 8 treatment groups with soak and spray technique using a disinfectant solution for 10 minutes. In each treatment group dimensional stability changes, except the control group because the treatment is not used. Technique that gives greater influence on changes in dimensional stability is the soaking technique. But the use of a variety of different disinfectant solution did not impact on the mold result. There are significant differences in the dimensional stability of the disinfection technique. Techniques greater dimensional stability is changing soaking technique. But the use of various disinfectant materials do not have a significant effect on the dimensional stability of alginate mold result. Recommended spraying disinfection action and further research needs to done on alginate. Keywords: Alginate, Dimensional Stability, Infection Control