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Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Core Subject : Health, Science, Education,
Education Medicine & Pharmacology Neuroscience Public Health
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 30 Documents
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Search results for , issue "Vol 14 No 4 (2024): Medula" : 30 Documents clear
Kejadian Reaksi Obat yang Tidak Diinginkan Asidosis Tubulus Ginjal Pada Penggunaan Ibuprofen Sebagai Obat Over the Counter Alifah, Ghina Nur; Pardilawati, Citra Yuliyanda; Kurniawati, Evi; Sukohar, Asep
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1061

Abstract

Ibuprofen is an analgesic drug that can be obtained easily by patients because it is an over the counter (OTC) drug.  Ibuprofen when used can risk the lives of patients who consume it incorrectly.  Ibuprofen is a drug that causes damage to the kidneys or is nephrotoxic.  In large doses ibuprofen has been reported to cause hypokalemia, rhabdomyolysis and renal tubular acidosis Article searches with data sources from either journals or books with keywords used to facilitate searches. Journal articles used through case reports collect case reports of renal tubular acidosis due to the use of ibuprofen. In some of the case reports found, the use of ibuprofen had exceeded the dose set for OTC treatment. Patients with an average age of 41 years and reports ranged in age from 33 years to 63 years. Female patients has dominated the reported cases. The use of ibuprofen that caused the adverse drug reaction event belongs to type C, which is Chronic for continuous and long-term use of the drug. Non-pharmacological therapy that can be done is diet by limiting acid-producing foods and increasing alkaline-producing foods. Handling carried out on patients can be in the form of fluid resuscitation, electrolyte replacement through alkaline therapy, and supportive therapy according to the patient's clinical condition. Alkaline therapy using NaHCO3 and KHCO3 can be a fluid replacement and correct acidosis and hypokalemia.
Manajemen Anestesi pada Lansia dengan Peritonitis Sekunder: Sebuah Laporan Kasus: Indonesia Enggar B, Dimas Fikri; Habibi, Bahtiar Yusuf; Maulana, Dendy
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1062

Abstract

Peritonitis is inflammation of the peritoneum, which is the thin serous membrane that covers the abdominal cavity and the organs inside. The incidence of peritonitis is more common in men than women with a prevalence of 68.4% in men. The largest age group is 10-19 years old, followed by 56-70 years old. Peritonitis is an acute abdomen which is an emergency. Delay in surgical procedures can cause severe organ dysfunction and worsen the prognosis of peritonitis. The type of surgical procedure performed to treat peritonitis is laparotomy. Laparotomy is performed through an incision in the abdominal wall down to the abdominal cavity. In laparotomy surgery, the type of anesthesia used is general anesthesia. General anesthesia is a temporary state of unconsciousness followed by the loss of pain throughout the body due to the administration of anesthetic drugs. Elderly patients generally have several anatomical and physiological changes associated with the aging process. A high risk of death is found in patients over 60 years of age due to concurrent pathological processes and comorbid factors. Although age is not a contraindication to anesthesia and surgery, the rate of death and perioperative illness in elderly patients is relatively higher. This case report discusses a 66 year old man with secondary peritonitis who complained of continuous abdominal pain for 3 days. An exploratory laparotomy was performed under general anesthesia on the patient. Careful planning and proper implementation during pre-operative, perioperative, and post-operative periods are essential for patient safety.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN LUARAN PENDERITA INFEKSI SUSUNAN SARAF PUSAT DI BANGSAL RAWAT INAP ALAMANDA RSUD Dr. Hi. ABDUL MOELOEK PROVINSI LAMPUNG Assidiq, Hans Pratama; Perdani, Roro Rukmi Windi; Darwis, Iswandi; Berawi, Khairun Nisa
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1066

Abstract

Infection of the Central Nervous System is a disease that can cause death and serious disability if not detected and treated appropriately. Meningitis was a specific cause of death for children under 5 years old during 2000-2013. In the Alamanda Inpatient, RSUD Dr. Hi. Abdul Moeloek, Lampung Province, during 2020-2021 there were 50 cases of CNS infections. The aim of this study was to determine the factors associated with the outcomes of CNS infection sufferers in the Alamanda Inpatient, RSUD Dr. Hi. Abdul Moeloek, Lampung Province. This research uses an observational analysis method with a cross sectional research design. The population of this study were pediatric patients with a medical diagnosis of central nervous system infection at the Alamanda Inpatient, RSUD Dr. Hi. Abdul Moeloek, Lampung Province, for the period January 2020 – May 2021, totaling 50 patients with a total sample population. Univariate analysis showed that 39 sufferers of CNS infections in the Alamanda Inpatient, RSUD Dr. Hi. Abdul Moeloek, Lampung Province, mostly aged > 1 year as much as 79.6%, male as much as 51.3%, type of infection is meningitis or encephalitis as much as 66.7%, GPCS score not comatose 79.5%, normal nutritional status 69.2%, long hospitalization >5 days 69.2% and survival outcome is 82.1%. Bivariate analysis using the Chi-Square test showed that the factors that had the most influence on the outcomes of CNS infection sufferers in the Alamanda Inpatient, RSUD Dr. Hi. Abdul Moeloek, Lampung Province., in order of long hospitalization, GCPS coma score, nutritional status, type of infection, and age. Meanwhile, gender does not influence the outcome of CNS infection sufferers in the Alamanda Inpatient, RSUD Dr. Hi. Abdul Moeloek, Lampung Province.
Penatalaksanaan Holistik pada Anak Usia 3 Tahun dengan Skabies Melalui Pendekatan Kedokteran Keluarga di Puskesmas Tanjung Sari Natar Ilmyasri, Siti Amalya; Putri, Sisy Rizkia; Zuraida, Reni
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1067

Abstract

Scabies is a dermatological disorder caused by the parasitic mite Sarcoptes scabei which is capable of digging tunnels in the skin and causing itching that gets worse at night. The aim of this study is to apply family doctor services based on evidence-based medicine to patients by identifying risk factors, clinical problems, and patient management based on a framework for solving patient problems using a patient centered and family approach. This study is a case report. The data obtained were primary data obtained through alloanamnesis, physical examination, and home visits and secondary data obtained from the patient's medical records. Patients and their families have poor personal hygiene. The patient's family has insufficient knowledge about scabies, the habit of using towels together, and there is no regular schedule for washing and changing bed sheets, pillowcases and blankets. After carrying out holistic and comprehensive management using a family medicine approach, patient evaluation results were obtained in the form of increased knowledge of the patient's family regarding scabies, reduced complaints, and changes in behavior in maintaining personal and environmental hygiene.
Osteogenesis Imperfekta dengan Bronkopneumonia: Sebuah Laporan Kasus Meidayanti, Devi; Apriyana, Ninike; Fadhila, Syifa Rahmi; Syafni, Alma Nazelia; Ivytha, Ivytha; Ismail, Ismi Citra
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1068

Abstract

Osteogenesis imperfecta (OI) or what is known as brittle bone disease (brittle bone disease) is a group of rare disorders that are hereditary. Prenatal diagnosis of pregnancies at risk for OI with fetal ultrasonography in the early 2nd trimester is feasible and allows treatment. The patient, a 2 month 23 day old baby, came to Abdoel Moeloek Hospital accompanied by his family with crooked legs since birth and shortness of breath since 1 day before entering the hospital. Other complaints experienced by patients include fever, weight loss since birth, broken bones. On physical examination, it was found that the general condition looked seriously ill, compos mentis consciousness, pulse 162x/minute, breathing 70x/minute, temperature 37.6˚C, SpO2 95% with Nasa cannula 1 lpm, the patient's nutritional status seemed poor, with body length 39 cm, upper body 26 cm, lower body 13 cm, and arm span 24 cm. According to the WHO growth chart, namely BB/U-2–0SD (normal); PB/U <-3 SD (severly stunted), the conjunctiva is not anemic, the blue sclera is positive, there is no visible breathing in the nostrils, the lips are not cyanotic, the thorax shows subcostal retraction, the breath sounds sound vesicular, there are fine wet crackles and there is no wheezing while heart within normal limits. A complete blood test showed that hemoglobin decreased by 8.8 g/dL, and hematocrit decreased by 28%, MCV 87fL, MCH 28 pg, MCHC 32 g/dL, suggesting normochromic normocytic anemia. Babygram showed the impression of osteogenesis imperfecta. The patient was diagnosed with osteogenesis imperfecta with bronchopneumonia and normochromic normocytic anemia.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PEMERIKSAAN PAYUDARA SENDIRI SEBAGAI METODE DETEKSI DINI KANKER PAYUDARA DI PUSKESMAS TEGINENENG KABUPATEN PESAWARAN Bajuri, Annisa Nur Oktavia; Sari, Ratna Dewi Puspita; Soleha, Tri Umiana
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1069

Abstract

Breast cancer is the uncontrolled growth of cells in the lobules, ductus and supporting tissue of the breast that surrounds them. An examination for early detection of breast cancer is breast self-examination (BSE) which can reduce the mortality rate by 25-30%. Pesawaran District in 2018 had a coverage of the PTM indicator for BSE examination of 16,20%, with the highest achievement at the Gedong Tataan Community Health Center of 27,83% and the lowest in Tegineneng Community Health Center of 4,17%. This research was conducted to determine the factors associated with BSE behavior in women of childbearing age (WUS) in Tegineneng Community Health Center, Pesawaran Regency. The research used an analytical observational method with a cross sectional approach. The sampling technique was cluster sampling. Data was collected using a questionnaire and analyzed with chi-square test. The results showed that there was a significant correlation between knowledge (p-value 0.003) and media information (p-value 0.000) on BSE behavior. There was a significant relationship between knowledge and information media on BSE behavior. Meanwhile, there was no significant relationship between age, motivation, and the role of health workers on BSE behavior.
Retinopati Diabetik yang Mengancam Penglihatan Oktaryona Trisera; Himayani, Rani; Apriliana, Ety; Yusran, M
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1070

Abstract

Diabetic retinopathy is a progressive microangiopathy characterized by retinal vascular damage and blockage. The global prevalence of diabetic retinopathy is 34.6%. Clinical manifestations in patients with diabetic retinopathy include aneurysms, vein dilation, vitreous hemorrhage, and hard exudates which can affect visual acuity. Progression of diabetic retinopathy can potentially threaten vision and even blindness even though initially there are no severe clinical manifestations. Visual-threatening diabetic retinopathy is classified into severe NPDR, PDR, and all DR with diabetic macular edema. The global prevalence of VTDR is 7.26% and according to research by Sasongko et al (2017) states that 1 in 4 DM patients has a vision-threatening DR condition (VTDR). The best management of DR is prevention in the form of early screening, education, and counseling, especially in DM patients. For patients who have been diagnosed with DR, follow-up treatment, laser, injection, or even surgery, depending on the severity.
Artikel Review: Aktivitas Antibakteri dan Antioksidan Tanaman Baru Cina (Artemisia Vulgaris L.) Suci Ainu Sella; Triyandi, Ramadhan; Afriyani, Afriyani; Iqbal, Muhammad
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1071

Abstract

Herbal medicines and their active ingredients have been a trusted source of treatment since ancient times. Herbal products with raw plant parts or bioactive compounds are increasingly in demand in the treatment of disease. Diseases caused by pathogenic bacteria have become an unresolved problem due to bacterial mutations that cause bacteria to be resistant to antibiotic agents. Long used as a medicinal plant, recent studies show that mugwort (Artemisia vulgaris L.) exhibits antioxidant, hypolipidemic, analgesic, antibacterial, antifungal, and hypotensive properties with chemical compounds such as flavonoids, sesquiterpene lactones, coumarins, acetylene, phenolic acids, organic acids, sterols, vitamins (ascorbic acid), monoterpenes, and sesquiterpenes. The content of mugwort (Artemisia vulgaris L.) can be used as a source of natural antioxidants, which can be used as ingredients for cosmetics, food supplements, and medicines. This plant can inhibit the growth of the bacteria Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae, Enterococcus sp., Propionibacterium acnes, and Staphylococcus epidermidis. From the literature, it is known that a 0.1% concentration of the test extract was able to inhibit bacterial growth, and a 5% concentration of methanol extract showed the best inhibition of bacterial growth with an inhibitory zone diameter of 24–25 mm. Plant antioxidant activity was tested using the DPPH method and the ORAC method. The best IC50 value was in the methanol extract, namely 4.3 µg/mL, with an ascorbic acid IC50 of 2.9 µg/mL. Meanwhile, the ORAC value was 5700 (µmol trolox EQ/g extract).
Potensi Tanaman Obat pada Penyakit Diabetes Melitus Dan Komplikasinya: Artikel Review Elisabeth Elva Monika; Triyandi, Ramadhan; Afriyani, Afriyani; Rahayu, Ihsanti Dwi; Iqbal, Muhammad
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1073

Abstract

Diabetes Mellitus (DM) merupakan kelainan metabolisme yang ditandai dengan hiperglikemia, yang dapat menyebabkan komplikasi mikrovaskuler dan makrovaskuler. Dalam rangka pencegahan dan pengobatannya, penelitian ini bertujuan untuk mengidentifikasi tanaman obat dan kandungannya yang mempunyai efek terhadap pasien diabetes melitus, menganalisis dampak penggunaannya, dan memastikan tanaman mampu mengobati komplikasi diabetes melitus. Dalam tulisan ini, metode yang digunakan adalah mengidentifikasi dan mengevaluasi temuan relevan tanaman obat diabetes melitus dari artikel, memanfaatkan mesin pencari Google dan Google Scholar dengan kriteria inklusi meliputi artikel penelitian yang diterbitkan dalam 10 tahun terakhir (2013 - 2023), full-text. artikel penelitian yang mudah diunduh, dan artikel ditulis dalam bahasa Inggris atau bahasa Indonesia. Hasil literatur ini menunjukkan bahwa beberapa tanaman obat seperti Bawang Putih ( Allium sativum ), Teh Hijau ( Camellia Sinensis ), Daun Kelor ( Moringa Oleifera ), Daun Sirsak ( Annona muricata ), Jahe ( Zingiber officinale ), dan Kumis Kucing ( Orthosiphon stamineus Benth.) ditemukan mengandung berbagai senyawa bioaktif dengan efek positif dalam menurunkan kadar gula darah, melindungi organ yang berhubungan dengan diabetes, dan mengurangi risiko komplikasi. Temuan ini memberikan landasan yang kuat bagi pengembangan terapi herbal sebagai pendekatan alternatif atau komplementer dalam pengobatan diabetes melitus.
Sepsis pada Pneumonia: Literature Review Farhana, Shabrina; Wahyuni, Ari; Lisiswanti, Rika
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1075

Abstract

Sepsis is a clinical syndrome that occurs as a complication of severe infection and systemic inflammation and widespread tissue damage. Over the past three decades, the incidence of sepsis has continued to increase and has become the leading cause of death compared to other common diseases in Western countries. The incidence of sepsis reaches 750,000 every year with mortality reaching 50% in patients experiencing sepsis and septic shock. Pneumonia is the most common primary infection that occurs in sepsis patients. Pneumonia ranks third highest worldwide. Pneumonia sufferers with sepsis account for 40% of all pneumonia sufferers. Severe sepsis can be triggered by infections that occur during medical treatment or can also occur from community-acquired infections (Community Acquired Pneumonia). The aim of this literature review is to provide an overview of epidemiology, pathophysiology, clinical manifestations, and therapy that can be carried out in patients with pneumonia complicated by sepsis. The results of this literature study show that clinical manifestations in patients are influenced by the location of the infection, the type of organism, and the severity or lightness of the infection. Therapy that can be carried out in patients with pneumonia with sepsis is initial resuscitation which includes administering 0.9% NaCL for 6 hours and vasopressors to maintain the patient's hemodynamics, as well as administering empiric antibiotics followed by antibiotics according to the culture results and resistance in the patient.

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