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Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Core Subject : Health, Science, Education,
Education Medicine & Pharmacology Neuroscience Public Health
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 906 Documents
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Perbandingan Efek Jus Buah Pare (Momordica charanti L), Jus Biji Petai (Parkia speciosa Hassk) Dan Kombinasi Keduanya Terhadap Kadar HDL (High Density Lipoprotein) Dan Kadar LDL (Low Density Lipoprotein) Darah Tikus Putih Jantan (Rattus Norvegicus) Galur andestya nanda pratama; Syazili Mustofa; Tri Umiana Soleha
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.546

Abstract

Background: Dyslipidemia is an abnormality of lipid fraction in blood plasma, Dyslipidemia can cause coronary heart disease (CHD) which is the main cause of death in the world. Bitter melon juice (Momordica charanti L), bitter beans juice (Parkia speciosa Hassk) has an antioxidant (antidislipidemia) that able to influence the LDL and HDL level. Purpose: Compare Bitter melon Fruit Juice, bitter beans Juice and the combination of HDL and LDL levels in male white rats with a high-fat diet. Method: An experimental study using a posttest control only design group. Using 30 white Wistar rats. There were 5 groups, there are the negative control group (K-) were only given a standard diet, 4 other controls were given a high-fat diet, the positive control group (K+) were only given 2ml/200gBB quail egg yolk, bitter melon (P1) 100ml/KgBB , bitter beans juice (P2) 100ml/KgBB/day, and combination juice (P3) 200ml/KgBB, for 14 days. Results: Average HDL levels in bitter melon juice group (78.73 ± 1.42 mg/dl), bitter beans juice group (65.74 ± 2.02 mg/dl), and combination juice group (70.37 ± 1.35mg/dl). The mean LDL level in the bitter melon fruit juice group (75.92 ± 1.28 mg/dl), bitter beans juice group (76.52 ± 1.20 mg/dl), and combination juice group (52.12 ± 1.20 mg/dl). The mean HDL and LDL levels in treatment groups were significantly different from negative (K-) and positive (K+) control groups with p <0.05 Conclusion: Giving fruit juice is better than HDL levels, and combination juice is better for LDL levels in male white rats on a high-fat diet.
Wanita G2P1A0 Hamil 39 Minggu Belum Inpartu dengan Eklampsi Janin Tunggal Hidup dan Suspek Pertumbuhan Janin Terhambat Karina Azlia Amanda; Karunia Santi; Ratna Dewi Puspitasari
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.548

Abstract

Eclampsia is a syndrome characterized by hypertension and proteinuria after 20 weeks of gestation and can be accompanied by organ damage and seizures. Preeclampsia and eclampsia are the causes of 30-40% of perinatal deaths and are one of the obstetric complications that cause a lot of morbidity and mortality in addition to bleeding and infection. The female patient, 21 years old, was taken to Abdul Moeloek Hospital by her family at the referral of Bumi Waras Hospital with complaints of pregnancy with high blood pressure and a history of seizures before hospital admission. From the examination of an obgyn specialist outside, an ultrasound was performed with the results of intauterine growth restriction. The gestosis index in this patient is 10. The diagnosis in this patient Gravida 2 Partus 1 Abortion 0 (G2P1A0) 39 weeks pregnant and not yet parturition with eclampsia of a live singleton fetus with cephalic presentation and suspect IUGR (intrauterine groth restriction). The patient received active management after receiving medical and observative therapy. Medical therapy consists of MgSO4, nifedipine and dexamethasone. The diagnosis and management in this case have been adjusted according to the reference.
Pengelolaan Limbah Obat dalam Rumah Tangga Tasya Nadia Putri; Winda Trijayanthi Utama
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.549

Abstract

Environmental pollution caused by drug waste has become a global concern because it can reduce the quality of human life. Based on Riskesdas 2018, 35.2% of households store drugs for self-medication. Drug waste is estimated to increase along with the population growth rate, followed by increased consumption of drugs in the community. Drug waste includes unused and expired drugs. Household drug waste is usually disposed of directly into landfills, so it has the potential to cause various problems in the environment, including damage to water, air, and soil, ecosystems, toxins for animals and humans. This article aims to determine the management of pharmaceutical waste in the household so that it does not cause negative impacts on health and the environment. The method of writing this article with a literature review is to analyze the management of drug waste in the household. Most people do not know the proper management of drug waste. Drug waste is disposed of without paying attention to the drug waste management system. The community is expected to be able to implement the management of drug waste in households to prevent environmental pollution that can reduce the quality of life.
Potensi Ekstrak Kulit Batang Bakau Minyak (Rhizophora apiculata) Sebagai Larvasida Terhadap Larva Aedes Aegypti Dzakwan Cedri Ketierteu; Jhons Fatriyadi Suwandi; Putu Ristyaning Ayu Sangging; Hanna Mutiara
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.577

Abstract

Dengue Hemorrhagic Fever (DHF) is a disease in humans which is transmitted by the Aedes aegypti mosquito as a vector which causes many cases of death. In Indonesia, the number of cases of dengue fever deaths will be 705 cases in 2021. Alternative natural insecticides are needed to avoid potential resistance to chemical insecticides. Rhizophora apiculata stem bark contains active compounds, namely saponins, flavonoids, alkaloids, and tannins which are larvicidal. The purpose of this study was to determine the larvicidal effectiveness of Rhizophora apiculata stem bark extract. This study used a laboratory experimental research design with a post test only control group design pattern. Divided into 6 groups, namely negative control, 0.045%, 0.09%, 0.18%, 0.36%, and positive control. Each group contained 25 larvae in 20 ml of Rhizophora apiculata stem bark extract solution with 4 repetitions. The data analysis used was univariate data analysis to find which concentration caused the highest death of Aedes aegypti larvae. From the research results, it was found that the average mortality of larvae from 4 repetitions at concentrations of 0.045%, 0.09%, 0.18%, and 0.36% were 68%, 97%, 99%, and 100% respectively.
Faktor Risiko Pasien Coronavirus Disease-19 (Covid-19) Saphira Murfi; Tri Umiana Sholeha; Rani Himayani
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.581

Abstract

Coronavirus disease-19 (Covid-19) is a disease caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus that has caused a worldwide pandemic and reached Indonesia in March 2020. This disease causes a various clinical manifestations from mild to severe, one of which also depends on risk factors that can exacerbate Covid-19 patients to the point of causing death. Risk factors that are often associated with Covid-19 diseases, such as age, race and ethnicity, gender, obesity, history of hypertension, chronic obstructive pulmonary disease (COPD), and diabetes mellitus. This is also related to the entry of viruses into the body that uses angiotensin-converting enzyme-2 (ACE-2), causing various risk factors to appear. This article is a literature review that was compiled using articles as references that were used between 2020-2022.
Penatalaksanaan Holistik Pada Wanita Usia 63 Tahun Dengan Penyakit Osteoarthritis dengan Hipertensi dan Dispepsia Melalui Pendekatan Kedokteran Keluarga thaharatin Giza; Azelia Nusadewiarti
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.585

Abstract

Osteoarthritis is a chronic disease characterized by damage of joint cartilage that causing stiffness, pain, and movement disorders. While hypertension is a condition where a person’s systolic and diastolic blood pressure is >140/90 mmHg. Both osteoarthritis and hypertension are diseases that must be managed comprehensively because they are chronic. Implementing family doctor services by identifying risk factors, clinical problems, as well as patient management based on evidence-based medicine that is family-approach, patient-centred dan community oriented. The study conducted is a case report. Patient, Mrs. S, a woman, 63 years old, has a complaint of pain in both knee joints since about 3 days ago. Pain felt come and go and getting worse especially in the morning with a duration is about 15 minutes. The patient has an additional complaint of headache and epigastric pain. The patient was diagnosed as osteoarthritis with hypertension and dyspepsia. Several factors can affect patient’s condition, both internal and external risk factors. In this case, diagnosis and treatment have been carried out according to the latest theory and journals. After the intervention, there was a decrease in clinical symptoms and an increase in the knowledge of patients and their families. The diagnosis of osteoarthritis with hypertension and dyspepsia in this patient was in accordance with the theory from several guidelines and journals, it was seen that there were a change in knowledge of the patient and his family after the intervention based on evidence-based medicine yang bersifat patient-centred dan family medicine approach.
G4P2A1 Hamil 38 Minggu Belum Inpartu dengan HAP e.c Plasenta Akreta dengan Riwayat SC Satu Kali, Janin Tunggal Hidup, Letak Lintang : Sebuah Laporan Kasus Fukrapti Fukrapti; Restu Krisnanda; Nurul Islamy
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.594

Abstract

Placenta accreta is the abnormal implantation of the placenta in the uterine wall. The risk factors for placenta accreta include a history of myometrial damage due to cesarean section, placenta previa, maternal age > 35 years, and multipara. Meanwhile, the transverse lie is when the position of the fetus is perpendicular to the mother. The predisposition factors for transverse fetal position are multipara, placenta previa, and uterine myoma. Mrs. YS, G4P2A1, 32 years old, was referred from Way Kanan Hospital with bleeding from the genitals 3 weeks before she entered to the hospital. The bleeding was fresh red, no pain, 3 times changing pads per day. The patient was diagnosed with placenta accreta at 6 months of gestation. Examination of vital sign, general physical examination, and complete haematological examination were within normal limits. Obstetrical physical examination revealed fundal height of 3 fingers bellow the Xyphoideus Processus with estimated fetal weight of 2.790 gram, and transverse lie. Ultrasound results showed the impression of a single live fetus in a transverse position, biparietal diemeter indicated 38 weeks 3 days of gestational age with the placenta closing the OUI, pathological lacunae, hypervascularization, and bridging vessels. The patient underwent laparotomy and total hysterectomy. Postoperatively, ceftriaxone 1 gram/12 hours IV therapy, tranexamic acid 500 mg/8 hours IV, ketorolac 30 mg/8 hours, and transfusions of 2 PRC and 2 WB kolf were given. Post-transfusion haemoglobin 10.8 g/dL.
Pengaruh Senam Kaki Diabetik terhadap Neuropati pada Pasien Diabetes Melitus Lutfia Qurotulnguyun; Fidha Rahmayani; Sutarto
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.455

Abstract

The prevalence of people with diabetes mellitus has increased every year. Indonesia is ranked 7th in the world with 10.7 million people with diabetes. Diabetes in the long term can cause macrovascular and microvascular complications. One of the main complication of diabetes mellitus is diabetic neuropathy. Diabetic neuropathy is a microvascular complication that causes peripheral nerve dysfunction, which attacks the lower extremities, especially the legs. About 50% people with diabetes mellitus experience diabetic neuropathy. If not treated properly, this condition can reduce the patient's quality of life, increase the risk of amputation, and even death. Drugs are often the main choice for therapy, but cost constraints and side effects cause interest to look for other treatment alternatives. Treatment that can be done is to exercise. One of the recommended sports is diabetic foot exercise. Diabetic foot exercise is a light exercise focused on the legs consisting of ten steps. This sport can be done easily, does not cost money, and does not take a long time. Several studies state that diabetic foot exercises can be an alternative to prevent and inhibit the worsening of neuropathy in patients with diabetes mellitus by helping to accelerate peripheral blood circulation and strengthen muscles in the lower extremities to prevent injuries and foot deformities.
Identifikasi Bakteri Gram Negatif Penghasil Extended Spectrum Beta-Lactamase (ESBL) Pada Urin Pengguna Kateter di Ruang Rawat Inap Kelas III RSUD Dr. H Abdul Moeloek Bandar Lampung Revina Rifda Amelia; Reyhan Anjani Putri; Tri Umiana Soleha
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.502

Abstract

Urinary catheterization is an action to insert a catheter into the patient's bladder through the urethra used in the hospital. The use of urinary catheters increases the risk of urinary tract infections (UTI) by about 5% every day. The incidence of nosocomial infection is 3 times higher in class III inpatients. According to research bacteria found as a cause of urinary tract infections due to urine catheters have a high enough potential to become a bacterium inhibiting Extended Spectrum Beta-Lactamase (ESBL). ESBL is a mutated β-lactamase enzyme, causing an increase in the enzymatic activity of β-lactamase, so that this enzyme can hydrolyze third generation sefalosporins and aztreonam. To find out the existence of ESBL-producing gram-negative bacteria in the catheter user urine in class III inpatients Dr. H. Abdul Moloek. This study used a categorical descriptive method with a cross sectional approach. The sample in this study were 22 patients who used catheters in class III inpatient rooms. Then the samples were tested for culture, biochemical tests and Double Disc Synergy Test. The results of a study of 22 patients undergoing a culture test found 4 patients with ESBL-producing gram-negative bacteria, 3 Escherichia coli bacteria (75%) and 1 Pseudomonas aeruginosa bacterium (25%) %), from these results the most bacteria producing ESBL is Escherichia coli. The conclusion is the highest amount of ESBL-producing bacteria was Escherichia coli (75%).
Penatalaksanaan Holistik Dermatitis Atopik Pada An. N Usia 12 Tahun Di Puskesmas Kota Karang Melalui Pendekatan Kedokteran Keluarga Kuntum Sureda; Refi Fandana; Sahab H. Sibuea
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.534

Abstract

Atopic dermatitis also known as eczema is the most common form of chronic dermatitis. This disease is generally synonymous with itching which is characterized by dry skin, chronic lesions, and lichenification. Atopic dermatitis is believed to be associated with other forms of IgE disorders such as allergic rhinitis, asthma, and food intolerance. This disease results in a high rate of morbidity and its prevalence has increased in recent decades. The study conducted is a case report. Data were obtained through history taking and physical examination by conducting home visits. The assessment is carried out based on a qualitative diagnosis, process, and visit. Based on the examination, the patient was a 12 year old girl with atopic dermatitis. Knowledge of patients and families about the disease is very limited. Education and intervention provided to patients and families about atopic dermatitis and risk factors that can trigger the occurrence of this disease. On internal factors in cases such as genetic factors, age factors, and ignorance of the originator. External factors are the lack of family knowledge about atopic dermatitis, its complications and the environment that has many allergens. Pharmacological and non-pharmacological interventions are carried out in the form of education in preventing the onset of atopic dermatitis symptoms in patients. In the evaluation of increasing patient compliance to avoid risk factors and family knowledge about patient care. Services with a family medicine approach in pharmacological and non-pharmacological therapy are able to solve health problems and improve the patient's quality of life.

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