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Contact Name
Risti Graharti
Contact Email
risti.graharti@gmail.com
Phone
+6281369730011
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medulla.fkunila@gmail.com
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Location
Kota bandar lampung,
Lampung
INDONESIA
Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Articles 906 Documents
Efektivitas Ekstrak Buah Adas (Foeniculum vulgare) Terhadap Penurunan Kadar Glukosa Darah Siti Maharani; Intanri Kurniati; Agustya Tjiptaningrum
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.574

Abstract

Diabetes mellitus is a condition that occurs when blood glucose levels exceed normal limits. This is caused by the pancreas not producing enough insulin or because the insulin produced is not effective in helping the absorption of glucose into the body's cells. The prevalence of diabetes in 2019 in the world is estimated to reach 463 million people aged 20-79 years. Diabetes mellitus affects more men in the world, namely 9.65% of the world's population, while the prevalence of sufferers is female as much as 9%. Indonesia is ranked 7th with the most diabetes mellitus sufferers in the world. Indonesia has as many as 10.7 million people with diabetes mellitus recorded. DKI Jakarta ranks first with the most diabetes mellitus sufferers in Indonesia, namely 3.4% of the population. Diabetes mellitus treatment does not aim to cure the disease completely, but only to control blood sugar levels so that they are within normal limits. One of the causes of diabetes mellitus is due to oxidative stress. One of the herbal plants known to have antioxidant content is fennel fruit (Foeniculum vulgare). occurrence of oxidative stress. Fennel contains flavonoids, saponins, cardiac glycosides, terpenoids, and tannins. These compounds have an antihyperglycemic effect by inhibiting alpha glucosidase. Flavonoids are antioxidant compounds that can play a role in preventing oxidative stress associated with diabetes mellitus.
FAKTOR RISIKO BAYI BERAT LAHIR RENDAH Nur Annisa; dyah wulan sumekar rw; fidha rahmayani
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.578

Abstract

Low birth weight babies are a preventable health problem in society. This is an important determinant of child survival and development, as well as long-term consequences such as the emergence of non-communicable diseases in their developmental lives. Babies with low birth weigth have a risk of fatality, development and growth delays compared to babies who are not LBW. In general, the causes of LBW are due to maternal and fetal factors, because while in the womb, the fetus receives the supplies it needs to survive from the mother. A large amount of mortality and morbidity can be prevented by addressing the factors associated with low birth weight. The aim of this literature review is to identify risk factors associated with low birth weight. Various studies have shown several risk factors for low birth weight babies, including maternal age during pregnancy and marital status, maternal diet, smoking habits during pregnancy, educational and socio-economic status, maternal activity during pregnancy and history of complications during pregnancy. But of course the existing research still has certain limitations, so further research is needed in the future.  
Tatalaksana Malaria Berat Gigaramadan Sema; Hanna Mutiara; Tri Umiana Soleha
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.584

Abstract

Malaria is a disease caused by the infection of Plasmodium parasite. Severe Malaria is accompanied by complications such as cerebral Malaria, seizures, acute kidney failure, hemodynamic shock, and so on. intravenous artesunate is the first-line treatment for severe Malaria caused by all Plasmodium species. Early RRT therapy is necessary to manage acute renal failure, also careful fluid resuscitation is important to prevent lethal pulmonary edema. Delayed-onset hemolysis following Artesunate administration necessitate hemoglobin checks and post-treatment monitoring. ACT treatment is the first line treatment after complications have subsided, followed by primaquine administration to treat relapse cases. G6PD testing is required before primaquine administration to prevent hemolysis.  
Laporan Kasus : Henoch Schnolein Purpura dengan Keterlibatan Sendi dan Gastrointestinal Nandya Dwizella; Umi Rinasari; Nevristia Pratama
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.586

Abstract

Henoch Schnolein Purpura (HSP) is one of the most Idiopatic Cutaneous Necrotizing Venulitis/Vasculitis, generally found on children compared to adult. The diagnosis HSP based on clinical manifestation which characterized purpuric with one or more following  athralgia/arteritis, renal involvement, gastrointestinal involvement or  Ig-A deposit  in tissue biopsy.  The aim is report a case of HSP with joint and gastrointestinal involvement. A 20-year-old woman came with red spots on both lower limbs and felt  joint pain and vomit, a history of similar red spot and joint pain felt intermittent since 6 years ago. There was history of pain in oral cavity 2 days before red spot appear.  Physical examination, vital signs were within normal limits, epigastric tenderness was found in abdominal examination. Dermatological examination in the cruris-dorsum pedis bilateral found macula erythematous, multiple, milier-lenticular, well-demarcated, discrete-confluent. Patients are diagnosed with HSP according to the clinical symptoms. Trigger factor for HSP is a history of infection. The patient was treated with acetaminophen, steroids, and topical therapy. Most HSP is self-limiting disease, supportive therapy is given to reduce clinical manifestation  and administration of corticosteroids prevent gastrointestinal complication
Polusi Udara dan Permasalahan terhadap Kulit Marcella Dena Fernanda; Hendra Tarigan Sibero; Hanna Mutiara
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.590

Abstract

Pollution has been shown to increasingly play a role in several common ailments, and the effects on the skin are no exception. Indoor and outdoor pollutants are widely distributed in urban and rural environments. WHO defines air pollution as contamination of the outdoor (ambient) and indoor (household) environment by any chemical, physical or biological agent that alters the natural characteristics of the atmosphere. Inhaled or ingested pollutants can be distributed throughout the body through the systemic circulation, making the exposed air a target for contaminants in the superficial and deep layers of the skin. The mechanisms by which pollutants may interact with human skin may differ based on each agent and its specific characteristics. Basic and clinical studies have provided growing evidence of the interaction of pollutants with the skin. Pollutants can activate skin metabolic and inflammatory pathways and induce oxidative stress by lowering antioxidant levels in particular. The skin is also a target for another known source of oxidative stress, namely UV radiation. The interaction of pollutants with UV light or the human skin microbiota requires further clinical investigation to evaluate their specific impact on skin health. Both outdoor and indoor pollution were found to increase signs of skin aging such as facial lentigines and wrinkles. Living in a polluted environment can also reduce skin moisture, increase the rate of sebum excretion and possibly worsen symptoms of chronic inflammatory skin diseases in both children and adults. Home location, type of work and diet all lead to internal and external exposure to a variety of pollutants, with clinical consequences that can accumulate or synergize. Pollutants are only one component of exposure which means that both internal and external factors must be considered when establishing pollution protection measures, which necessitates the development of standard methods for their evaluation. This literature review provides an overview of how pollutants affect the health of the skin.
Anemia pada Pasien Tuberkulosis Inna Kurniaji; Waluyo Rudiyanto; Indri Windarti
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.592

Abstract

Tuberculosis (TB) is one of the most common causes of health problems in the world. The prevalence of TB in the world is estimated at 10.6 million, and 1.6 million of them died from TB, in Indonesia the incidence of TB reached 503,712. Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis, which is known to cause complex hematological disorders. The hematopoietic system is thought to be affected during TB infection, so that Hb levels tend to decrease along with bacterial increase, which eventually causes anemia. The article aims to determine the incidence of anemia in TB patients and the mechanism of anemia in TB patients. Based on the results of a literature review conducted on references found from 2012–2022, it shows that anemia is a common condition in TB. The mechanism that causes anemia in TB patients is due to its pathogenesis as a chronic inflammatory disease. Anemia is an indicator in providing clues to diagnosis, prognosis, complications and response to TB therapy. Nutritional intake and adherence to TB therapy need to be done properly to prevent the development of severe disease and improve the patient's quality of life.
Pengaruh Sarapan terhadap Konsentrasi Belajar Puteri Sahra Salsabila; Shinta Nareswari
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.593

Abstract

Breakfast is a daily consumption that is considered important to meet nutritional needs. Even though it is considered important, there are still many people who skip breakfast which can have a negative impact on the learning process at school, contribute to obesity, and increase the risk of unhealthy snacks. Breakfast should be done to support learning concentration and meet the nutritional needs needed by the body. Learning is defined as all psychological activities carried out by everyone so that their behaviour is different before and after learning. Attention to learning has been identified as a complex construct in psychology that does not express a unitary concept but involves psychological phenomena that interact with all other cognitive processes. In general, the brain works best when blood glucose levels are in the 80–120 mg/dL range. With the gradual depletion of blood glucose and the consequent energy consumption, people start to feel hungry and tired and experience a decline in cognitive function. A number of studies have reported that eating breakfast decreases cognitive function and work efficiency. Periods of fasting at night, depleting the glucose in the blood. So, in order to maintain its function, the brain needs intake in the morning. As an initial energy supplier, especially as a source of glucose energy for the brain, breakfast is highly recommended for everyone.
Hubungan Antara Asupan Makanan Terhadap Diabetes Mellitus Tipe 2: Sebuah Studi Pustaka Putu Arya Indira Prameswari; Reni Zuraida
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.595

Abstract

Type 2 diabetes mellitus (DMT2) is a global health problem with a significant impact on life. The prevalence of DM in the world reached 537 million people in 2021. DMT2 is a metabolic disorder caused by increased blood glucose levels. One of the risk factors DMT2 is dietary intake. Dietary intake is the main cause of the rapid increase in the incidence of DM in developing countries. Blood glucose levels are mainly influenced by dietary carbohydrates, high intake of fast food, carbonated drinks, intake of red meat, sweet foods and excessive intake of white rice are also thought to contribute to an increased risk of insulin resistance in DMT2. Based on this, the author are interested in conducting a literature study about the relationship between dietary intake and type 2 diabetes mellitus. Based on the literature study, it can be concluded that there is a significant relationship between dietary intake and DMT2 so that food intake can affect the incidence of DMT2 in individuals. Various types of dietary components can affect the risk of developing DMT2, therefore healthy dietary intake and regular diet patterns can be done to reduce the risk of various diseases.
MIASTENIA GRAVIS: ETIOLOGI, PATOFISIOLOGI, MANIFESTASI KLINIS, PENEGAKKAN DIAGNOSIS DAN TATALAKSANA KHAIRUNNISA SALSABILA; Hanna Mutiara; Rizki Hanriko
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.598

Abstract

Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating weakness of the extraocular, bulbar, and proximal muscles. Muscle weakness that occurs will worsen with activity and improve after rest. Myasthenia gravis is caused by the presence of autoantibodies on the postsynaptic membrane at the neuromuscular-junction (NMJ), such as antibodies against acetylcholine receptors, MuSK and LRP4. Myasthenia gravis is a rare neurological disease, the incidence is only about 1.7-21.3 per 1,000,000, has a bimodal distribution in women, with a peak of incidence at the age of 30-50 years. Men have a higher proportion after age 50. Myasthenia gravis is mostly a treatable disease but can result in significant morbidity and even death, so writing this literature review aims to discuss the pathophysiology, clinical manifestations, diagnosis and current treatment options for MG so as to increase the accuracy of the very early diagnosis. plays an important role in early management, as well as prevention of worse disease progression. The diagnosis of MG is based on anamnesis, neurological examination, electrodiagnostics, serology, and CT scan of the chest to see the presence of thymoma. The main treatment for MG is cholinesterase enzyme inhibitors and immunosuppressive agents. Symptoms that are resistant to primary treatment modalities or that require rapid resolution, such as in a myasthenic crisis, may require plasmapheresis or intravenous immunoglobulin treatment. Thymectomy can also be done.
HOLISTIC MANAGEMENT OF 63 YEARS OLD GERIATRIC MAN WITH AXIAL NECK PAIN THROUGH THE FAMILY MEDICINE APPROACH Hana Nafisah; Clara FIrhan Asifa; Dian Isti Angraini
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.602

Abstract

The most common health problem at work is musculoskeletal disorders (MSDs). One of the most common complaints of MSDs is pain in the neck muscles or axial neck pain. Axial neck pain is often exacerbated and has many risk factors, especially related to workplace ergonomics. Comprehensive management is needed so that risk factors can be identified, and holistic management can be given. Application of evidence-based medicine-based family doctor services by identifying risk factors, clinical problems, and patient management based on a patient problem-solving framework using a patient-centered and family approach. Primary data were obtained through anamnesis, physical examination, supporting examinations and home visits to assess the physical environment. The patient complains of pain in the back of the neck accompanied by a feeling of stiffness in the neck. Complaints felt since 1 week ago. The pain is felt like squeezing, comes and goes, decreases slightly when you apply warm oil and rest, but a few moments later the pain will recur, the pain gets worse after working lifting heavy weights on your shoulders or turning your neck to the right and left and lowering your head. Pain also radiates from the back of the neck to the shoulders, shoulder blades and upper back. Pain does not radiate down the arm. According to the patient's statement, the pain scale felt by the patient between 1-10 is 7. Diagnosis and management of this patient is carried out holistically and comprehensively, patient center, family appropriate, community oriented with drug administration, carrying out ergonomic guidelines at work and doing cervical exercises regularly according to the EBM so that it can prevent recurrence of axial neck pain.