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Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Core Subject : Health, Science, Education,
Education Medicine & Pharmacology Neuroscience Public Health
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 906 Documents
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KARAKTERISTIK TUMOR PAYUDARA PADA WANITA UMUR 35 - 65 TAHUN DI RSUD DR. H. ABDUL MOELOEK BANDAR LAMPUNG TAHUN 2018 Rima Nurbaiti; Festy Ladyani Mustofa; Ratna Purwaningrum; Nengah Budiarta
Medula Vol 13 No 2 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i2.507

Abstract

Cancer has a unique characteristic, which consists of malignant cells that can spread to other parts of the body. This spread is called metastasis and can occur through blood vessels or lymph vessels.This research is observational descriptive by using a cross sectional method approach using purposive sampling technique with a total of 105 samples. Data collection began in November 2019. This research was conducted at RSUD Dr. H. Abdul Moeloek Bandar Lampung. Statistical data chi-square test using SPSS 25. The research respondents obtained totaled 105 samples obtained 88 subjects. Respondents with > 40 years are as many as 66 people (75.0%), family history of breast tumors as many as 4 people (4.5%). radiation history as many as 3 people (3.4%). history of using hormonal family planning as many as 26 people (29, 5%). tumor size >5cm as many as 52 people (59.1%). Types of malignant tumors as many as 57 people (64.8%). The majority of respondents were > 40 years old, had a family history of breast tumors, and a history of radiation, a history of using hormonal contraception.
. Metode Gyssens Sebagai Pilihan Utama Dalam Evaluasi Kualitatif Penggunaan Antibiotik di Indonesia Dheti Efrilia -; Novita carolia; syazili mustofa; rasmi zakiah oktarlina
Medula Vol 13 No 2 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i2.526

Abstract

Antibiotic resistance is a global health problem in the world. Antibiotic resistance is defined as the absence of inhibition of bacterial growth by systemic administration of antibiotics with normal doses or minimal inhibitory levels. The World Health Organization (WHO) seeks to control antibiotic resistance globally by making global action plans to combat bacterial resistance to antibiotics, namely increasing the wise use of antibiotics and evaluating the use of antibiotics. The qualitative evaluation that can be used is the Gyssens method. The Gyssens method was chosen because this method has more specific aspects to evaluate each of the important parameters included in the use of antibiotics such as indication, effectiveness, safety, price and spectrum, and can also evaluate treatment duration, dose, interval, and route of administration as well as time of giving. Therefore, this method is the main choice for evaluation of antibiotics in Indonesia.
Efek Samping Sectio Caesarea Metode ERACS (Literature Review) Arifaa Thalitha Z.; Liana Sidharti; Evi Kurniawaty
Medula Vol 13 No 2 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i2.596

Abstract

Sectio caesarea surgery or cesarean section is a labor procedure to remove the baby through an incision in the abdomen (laparotomy) and uterus (hysterotomy). These surgeries are increasing all over the world (ACOG, 2021). The level of this operation continues to increase as evidenced by the report from the World Health Organization or WHO which will be published in 2021. The research was conducted using the literature review method. Literature review is a systematic, explicit and reproducible method for identifying, evaluating and synthesizing works. research results and ideas that have been produced by researchers and practitioners. The results of observations during the study on post-sectio caesarea (SC) birth mothers with the ERACS method, it was found that the implementation of early mobilization after 2-4 hours after surgery, most of the respondents were able to sit, and some even dared to stand. Then, after 8-10 hours, almost all of the respondents had removed the catheter, and some of the respondents had even taken a walk. After 13 hours after surgery, all respondents, based on the discussion above, which referred to several articles and journals, showed that the Caesarean section method had significant side effects, but there were also several advantages to the ERACS method, namely being able to make it easier and more effective in giving birth.
PENATALAKSANAAN HOLISTIK PENYAKIT EPILEPSI PADA PASIEN REMAJA DENGAN TINGKAT PENGETAHUAN YANG MINIMAL MELALUI PENDEKATAN KEDOKTERAN KELUARGA Riska Priyani; Cindy Gustavia Dwirusma; Diana Mayasari
Medula Vol 13 No 2 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i2.603

Abstract

In developing countries, the incidence of epilepsy is 61-124/100,000 children per year. The prevalence of epilepsy cases in Indonesia is 8.2 per 1,000 population with an incidence rate of 50 per 100,000 population. In the management of epilepsy patients, cooperation from various parties is needed, one of which is the role of family doctors. Identify internal, external risk factors and clinical problems found in patients, apply a holistic and comprehensive family doctor approach according to the problems found in patients, and carry out evidence-based medicine management that is family-approach, patient-centered and community oriented. The study is a case report. Primary data were obtained through history taking, physical examination and home visits. Secondary data were obtained from the patient's medical record. Assessment was qualitatively and quantitatively carried out based on the initial holistic diagnosis, process, and end of the visit using food recall. A male patient, 17 years old, came to take an epilepsy control referral letter to the hospital. The patient has been diagnosed with epilepsy since 7 years ago. Patients routinely take medication to the hospital every month. At this time the patient said that the seizures began to decrease after taking the drug every day. Enforcement of diagnosis and management of these patients has been done holistically, patient centered, family approach and community oriented based on several theories and the latest research. In the process of behavior change, the patient has reached the trial stage
Literature Review: Kejadian Resistensi Pada Penggunaan Antibiotik Cindy Ivana Putri; M.Fitra Wardhana; Femmy Andrifianie; Muhammad Iqbal
Medula Vol 13 No 3 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i3.629

Abstract

Antibiotic resistance is the ability of microorganisms to inhibit the action of antimicrobial agents and this phenomenon occurs when antibiotics lose their efficiency to inhibit bacterial growth. The increasing use of antibiotics in various health and agricultural sectors has led to the emergence of antibiotic resistance worldwide. Its irrational use can cause several problems. This incident causes antibiotic therapy to be no longer efficient and increases the cost of therapy. This resistance occurs in several types of microorganisms with a high prevalence that threatens human health. Antibiotic resistance can arise from mutations in pre-existing bacterial genomes. Mutations due to the external environment make a smaller contribution to the occurrence of resistance. Therefore, this literature review aims to provide an overview of the incidence of resistance in the use of antibiotics. The literature search was carried out using the Pubmed, Google Scholar and Mendeley electronic databases. The inclusion criteria in writing this literature review are articles in Indonesian and English with a range of article publications in the last 10 years (2013-2022). Research articles that cannot be accessed completely will be excluded. Overall the studies found and analyzed reported the incidence of resistance to the use of antibiotics. Almost all studies describe the percentage of occurrence of antibiotic resistance against certain bacteria. The increasing use of antibiotics has created high evolutionary pressure for the emergence of antibiotic resistance for bacterial survival.
Nutrasetikal Sebagai Terapi Komplementer Pada Major Depressive Disorder (MDD) Era Yesica Damanik; Mirza Junando; Muhammad Fitra Wardhana
Medula Vol 13 No 3 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i3.630

Abstract

Major depressive disorder (MDD) is known as a type of major depression characterized by altered mood, impaired cognitive function, anhedonia (inability to be able to feel pleasure), vegetative disorders such as insomnia, and fatigue or anorexia. Major depressive disorder (MDD) is one of the most common mental disorders worldwide, as well as one of the most disabling. The current treatment is inadequate so that about two-thirds of those treated with first-line antidepressants do not achieve remission. A therapeutic approach using nutraceutical can improve the response to cases of resistance in antidepressants. Nutraceutical is used as the prevention and treatment of various diseases or neurological disorders without or minimal side effects. A therapeutic approach using nutraceutical can improve the response to cases of resistance in antidepressants by targeting neurobiological pathways associated with the pathophysiology of depression. The purpose of writing this article is to find out the nutraceutical that can be consumed as complementary therapies of major depressive disorder (MDD). The source search method is done through the Google Scholar and Pubmed search engines. The results of the search found several nutraceutical, namely Probiotics, Omega-3 Polyunsaturated Fatty Acids (n-3 PUFAs), Vitamin D, S-Adenosylmethionine (SAMe) and Lactobacillus Plantarum HRAL9 have antidepressant activity. Nutraceutical has the potential to be a complementary therapy in effective major depressive disorder (MDD) therapy.
Covid 19 with Kidney Failure Arsistya Ayu Marella; Khairun Nisa Berawi; Fitria Saftarina
Medula Vol 13 No 3 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i3.632

Abstract

Corona virus disease 2019 or commonly called COVID-19 is a disease caused by infection with the SARS-CoV-2 virus and is one of the biggest challenges facing humanity in recent years. This disease is highly contagious with various manifestations and complications and poses a threat to public health. This virus can infect a large number of organs, including the lungs and upper respiratory tract, brain, liver, kidneys, intestines and many others. Although the greatest damage occurs in the lungs, the kidneys are no exception, and acute kidney injury (AKI) can occur in patients with COVID-19. AKI is one of the most frequent and serious organic complications of COVID-19. The incidence of COVID-19 AKI. During the COVID-19 pandemic, many patients were hospitalized with severe respiratory illnesses and experienced complications. Acute kidney injury (AKI) is one of the more dangerous complications that contributes to morbidity and mortality among patients. Kidney damage can occur due to direct attack by the virus itself, or due to a cytokine storm caused by an abnormality of the immune system. Hypotension or dehydration, hypoxaemia, sepsis and nephrotoxic drugs can also cause kidney failure. This research method begins by searching articles on Google Scholar, pubmed and ncbi within the year range determined by the researchers and using the keywords COVID-19, kidney failure, complications of kidney failure in COVID-19 patients. The results of the study found articles about producing several conclusions such as the effect of kidney failure on COVID-19 patients, then the long-term effects on the kidneys of patients with COVID-19.
Konjungtivitis dan COVID-19 Rifqi Fadhil Maulana; Nanda Cynthia Huzna; Rani Himayani
Medula Vol 13 No 3 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i3.649

Abstract

The coronavirus disease 2019 (COVID-19) pandemic started as an outbreak in Wuhan and has since spread worldwide. To date, the exact transmission route of COVID-19 is still unclear. The respiratory tract may not be the only route of transmission of this virus. Some studies have hypothesized that COVID-19 droplets, or contaminated hands, may also contaminate the conjunctiva and serve as an initial site of infection. Conjunctivitis, a common disease caused by either bacteria or viruses, has previously been described in association with coronavirus infections in some studies. Further reports suggest that when no eye protection is used, the virus can also be transmitted through aerosol contact with the conjunctiva and cause infection. However, the possibility of SARS-CoV-2 transmission through the conjunctiva is still controversial. Despite some controversy about whether the conjunctiva functions as an important route for SARS-CoV-2 infection, there is accurate evidence that the conjunctiva plays a role as an entry point and reservoir for the virus. Additionally, there is a possibility that unknown receptors in the conjunctiva may be involved in SARS-CoV-2 infection. The level of viral replication in the conjunctiva is still unknown and is another factor that can describe the impact of the eye in the pathogenesis. Studies have shown that SARS-CoV-2 viral RNA is more likely to be found in the ocular secretions of COVID-19 patients who have conjunctivitis symptoms, although it has also been found in patients without eye disorders in some cases. This literature review discusses the relationship between SARS-CoV-2 and conjunctivitis.
Ruptur Ureter Sinistra Pasca Histerektomi atas indikasi Adenomiosis Uteri dan Kista Endometrium Ghania Alizar; Nabila Quinsy Chiqita; Rodiani -
Medula Vol 13 No 2 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i2.650

Abstract

Adenomyosis is a benign gynecological disorder that invades endometrial tissue into the myometrial lining and suspected as one of the causes of subfertility in women. Adenomyosis usually diagnosed in the 4-5th decade of life, at the end of the reproductive period and perimenopause, but currently many women of reproductive age already suffer from adenomyosis, several studies suggest that this is influenced by lifestyle changes. A 45-year-old female patient was admitted to the emergency department with complaints of difficulty urinating after a hysterectomy 8 days before admission to the hospital for indications of adenomyosis and endometrial cysts. In the anamnesis, the patient complained of only a small amount of fluid coming out of the drainage and urinary catheter and 4 days before admission to the hospital there was no flow of urine coming out of the urinary catheter. This patient then underwent ureteroscopy and found signs of left 1/3 distal ureteral rupture. Operative management consists of neoimplantation and placement of a Double J stent in the left ureter. After 4 days postoperative, the patient was allowed to go home.
PENGARUH ALGAE MERAH (EUCHEUMA SPINOSUM) TERHADAP INFEKSI ESCHERICHIA COLI Putu Urvasi Ari Utami; Ety Apriliana; Rika Lisiswanti; Liana Sidharti
Medula Vol 13 No 3 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i3.651

Abstract

Bacteria can contribute to the development of diarrheal disease through direct contact with those who have the condition, consumption of food and drink contaminated with feces, or both. In addition, water, food sanitation, family latrines are the main causes of diarrheal disease. Among the causative bacteria, Escherichia coli is the most common pathogen for diarrhea in children in developing countries and an associated entero-pathogen of emerging antimicrobial resistance in developed countries. Reports of increased antibacterial resistance have become a challenge in handling diarrhea cases. Eucheuma spinosum is a species of red algae which is a marine organism that has been screened for phytochemicals and found to contain active substances such as flavonoids, triterpenoids, alkaloids, and ascorbic acid. Phenol compounds and their derivatives (flavonoids) are predicted to be compounds in E. spinosum that have the potential to inhibit E. coli bacteria by damaging the bacterial cytoplasmic wall.

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