Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Pharmaciana: Jurnal Kefarmasian

PHARMACIANA
Website

Published by Universitas Ahmad Dahlan

ISSN : 20884559 EISSN : 24770256 DOI : 10.12928

Core Subject : Health,

Medicine & Pharmacology

Pharmaciana is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Pharmaciana published three times a year, namely March, July and November. with ISSN 2088-4559 and e-ISSN 2477-0256. The article published in the Journal Pharmaciana selected by editors and reviewed by the reviewer. Articles published in Pharmaciana must not be published in other journals or have been previously published. Pharmaciana is indexed in google scholar, ACI (Asean Citation Index), Dimension (Crossreff), Garuda, Sinta, Sherpa Romeo, Index Copernicus International, DOAJ, and BASE. Pharmaciana is accredited by DIKTI (DGHE) of Indonesia No. 105/E/KPT/2022 April 07, 2022

Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)

Articles 808 Documents

31 32 33 34 35

KUALITAS PELAYANAN FARMASI BERDASARKAN WAKTU PENYELESAIAN RESEP DI RUMAH SAKIT Nita Rusdiana; Rahayu Wijayanti; Sri Wahyuni
Pharmaciana Vol 5, No 2 (2015): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Based on Standard of Pharmaceutical Quality in Hospitals, there are methods are applied to distribute pharmaceuticals. One outpatient care efforts is to obtain medication prescribed by a doctor in a short time. The quality of outpatient pharmacy services as measured by the time of complete prescription at the pharmacy installation hospitals are based on reliability, responsiveness, assurance, empathy and tangibles. The study use cross-sectionalâ€™s method, which is done by January-February in 2015, to analyze pharmacy quality standard and time of complete prescription. The data used in this study are primary data. This study was used sample of 157 respondents for quetioners and 787 outpatients prescriptions. The results showed that the highest satisfaction turn around time is 13 minutes. For the five variables tested showed that the responsiveness had the highest scores of 3.18 and tangibles has the lowest score of 2,53. Conclusion, time of complete prescription less than 13 minutes and supported by quetioners shows the highest variables of responsiveness at 3,29 are agreed that time to wait is not too long.

Effect of different preparation techniques of red dragon fruit (Hylocereus polyrhizus) extracts on normal human fibroblast viability Novi Febrianti; Triana Hertiani; Sukarti Moeljopawiro; Sofia Mubarika Haryana
Pharmaciana Vol 9, No 2 (2019): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Red dragon fruit is one of the popular fruits that have been widely used both for consumption and food coloring. The red dragon fruit peel and flesh contain various antioxidant compounds that can be used as pharmaceutics and nutraceuticals. The objective of this study was to determine the effect of various extract preparations of the peel and the flesh of red dragon fruit on the viability of normal human fibroblasts. Seven conditions of peel and flesh extracts were prepared as follows, i.e. dried peel ethanolic extract, fresh blended peel ethanolic extract, dried flesh, fresh blended flesh ethanolic extract, blended fresh flesh, filtrate of pressed flesh, and pomace of pressed flesh. Each sample preparation was tested for its effect on the viability of normal human fibroblasts using MTT assay. Results showed that dried peel ethanolic extract reduce cell viability. Red dragon fruit flesh extracts caused no significant effect on the fibroblast viability. In conclusion, the fruit flesh extracts are relatively safer to normal cells than the peel extracts. IC50 value of the ethanolic extract of dried peelÂ was 55.38Â±3.85 Âµg/mL, while the IC50 value of various types of flesh extract were more than 500 Âµg/mL.

Efek hidrogel getah jarak cina (Jatropha multifida Linn.) berbasis karagenan kappa dan karagenan iota terhadap penyembuhan luka tikus wistar jantan Fetri Lestari; Gita Cahya Eka Darma; Rikka Kartika
Pharmaciana Vol 6, No 2 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Jatropha multifida Linn. latex has been reported in many study for its activities to treats wound. Preparation of hydrogels containing 3% ofÂ Jatropha multifida Linn. latex with variety of base polymers kappa carrageenan and iota carrageenanÂ was conducted and met good characteristics. This study aimed to evaluate effect of both hydrogels to promote wound healing in Wistar rats. Tests carried out on five groups of rats with 1.5 cm diameter of wound in the back area, consisting of a control group, two test groups were each treated by 2% kappa carrageenan-based hydrogel (kappa-hydrogel group) and 2% iota carrageenan-based hydrogel (iota-hydrogel group) of the latex, and two groups were each given a different hydrogel base according to type of hydrogel tested. Effect on wound healing was assessed by parameters including wound drying period, scab forming period, and the change in diameter of the wound. Results show kappa-hydrogel group achieve the most rapid wound healing compare to the control group significantly (p<0,05) and the iota-hydrogel group on wound drying period (16.6 Â± 2.2 hours) and scab forming period (92.6 Â± 2.2 hours). Kappa-hydrogel group also show best changes in diameter of the wound at day 21 which is reduced to 0.02 Â± 0.03 cm, compare to the control group and iota-hydrogel group. As a conclusion, the 2% kappa carrageenan-based hydrogel containing 3% ofÂ Jatropha multifida Linn. latex produce better effect to promote wound healing than iota carrageenan-based hydrogel in this study.Â

SINTESIS SILIKA MCM-41 DAN UJI KAPASITAS ADSORPSI TERHADAP METILEN BIRU Mustofa ahda; Sutarno Sutarno; Eko Sri Kunarti
Pharmaciana Vol 3, No 1 (2013): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Synthesis of MCM-41 with hydrothermal time variation 18, 24, 36, 48 hoursusing templating agent cetiltrimetilammonium bromide (CTAB) has been done. Theresults showed that the time of hydrothermal influence the intensity and the index field(ao). Synthesis of MCM-41 with a time of hydrothermal 24 hours produce the highestintensity which indicates that MCM-41 has the best crystallinity. While testing theadsorption capacity of MCM-41 has 37,037 mg/g for adsorption of the methylene blue.

Efek perlindungan kombinasi kuersetin dan omega-3 terhadap sel Î² pankreas tikus dm tipe 2 Asri Hendrawati
Pharmaciana Vol 7, No 1 (2017): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Diabetes melitus (DM) merupakanÂ penyakit metabolikÂ yang menyebabkan kerusakan sel termasuk pankreas. Kuersetin danomega-3 telah diteliti sebagai terapi tambahan pada DM karena dapat menurunkan stres oksidatif dan mencegah kerusakan sel. Tujuan penelitian ini adalah mengetahui efek kombinasi kuersetin dan omega 3 dalam melindungi sel Î² pankreas dari kerusakan pada tikus DM. Subyek terdiri dari 28 ekor tikus, dibagi menjadi 1 kelompok sehat dan 6 kelompok DM tipe 2 (4 ekor perkelompok). Bahan uji adalah kuersetin dosis 5, 20 dan 80 mg/kgBB/hari dan omega-3 dosis 25, 100 dan 400Â mg/kgBB/hari peroral selama 4 minggu. Setelah perlakuan, jaringan pankreas diambil untuk pengecatan hematoksilin-eosin dan dihitung persentasekerusakannya.Pada penelitian ini, kombinasi kuersetin 80 mg/kgbb/hari dan omega-3 400 mg/kgbb/hari menurunkan tingkat kerusakan sel Î’ pankreas paling baik secara bermakna (p<0,05) dari pada kombinasi dosis lebih kecil maupun kuersetin saja atau omega-3 saja. Jadi kombinasi kuersetin 80 mg/kgbb/hari dan omega-3 400 mg/kgbb/hari menurunkan tingkat kerusakan sel Î² pankreas paling baik secara bermakna jika dibandingkan kombinasi dosis lebih kecil maupun tanpa kombinasi.Kata Kunci: Kuersetin, omega-3, diabetes melitus tipe-2, histologi sel Î² pankreas, hematoksilin-eosin.

GAMBARAN PASIEN GERIATRI MELAKUKAN SWAMEDIKASI DI KABUPATEN SLEMAN Woro Supadmi
Pharmaciana Vol 3, No 2 (2013): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The increase in life expectancy caused geriatric population is also increasing. Geriatric patient is identicalto the decline in physiological function that can lead to various diseases. Self medication in geriatric requirespecial attention from the pharmacist. The purpose of this study was to determine the description of geriatric thatdoes self medication and assosation factors in geriatric patients doing the self medication in Sleman. This researchwas conducted using a survey to determine the presence of pharmacy in Sleman. Determination of pharmaciesconducted with a purposive sampling technique and determination of areas of research subjects or respondentswith accidental sampling. Subjects were geriatric patients with age> 60 years who did self medication inpharmacies. The data were analyzed by using chi-square statistic to determine which are the most influentialassociation factors. The research subjects in this study was 38 respondents. The pattern of disease that occur ingeriatric patients who performs a self-medication is a chronic 12 respondens, non-respondens and 16 non chronicrespondens ten respondens is unknown. Factors that association geriatric patients that is doing self medication isown of health insurance. The results of the chi square test showed that the sex factor with OR 1,11 ( p >0,05),ownership asurance (OR = 1,841,p < 0,05,CI : 1,184 â€“ 2,184) is a factor of self association with geriatric patientsmedications at the pharmacy of district Sleman.

EVALUASI PENGGUNAAN OBAT ANTI HIPERTENSI PADA PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISIS Woro Supadmi
Pharmaciana Vol 1, No 1 (2011): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The intervention led to various complications in dialysis patients include hypertension intradialitik as a result of hemodynamic changes.The phenomenon of the paradox of which caused activation of endogenous vasopresor due to changes in volume status and antihypertensive medication terdialisisnya factor. This study aims to determine patterns of use of antihypertensive drugs, evaluating the rationality and side effects of antihypertensive drugs based on literarur. This study was performed with the patient’s condition based on the observation of patients to see medical records drug data, laboratory data of patients and patient’s condition.Retrospective study of hemodialysis patients in the hospital PKU Muhammadiyah Yogyakarta year period from 2009 to 2010.Patients according to inclusion criteria, anti-hypertensive drug receipts and complete medical record data.Evaluation of rationality involves the use of antihypertensive drugs right dose, right patient and side effects based on the Drug Information Hand Book 2005, Handbook of Clinical Drug Data, 2002. The study found 60 patients who fit the inclusion criteria.Based on the research patterns of use of antihypertensive drugs in patients with hemodialysis is captoril, furosemide, nifedipine, lisinopril, amlodipine, valsatran and clonidin. Evaluation rationality inappropriate use of drugs dose use of captopril 11 patients of 34 patients and furosemide 18 patients from 52 patients, inappropriate use of captopril patients was 9 patients of 34 patients.Side effects that occur in patients with hypokalemia due to the use of furosemide is 40 patients, cough due to captopril was 13 patients, side effects of nifedipine gastrointestinal disorders cough and 11 patients, 5 patients cough lisinopril.Conclusion:he use of antihypertensive medications in hemodialysis patientsat RSU PKU Muhammadiyah Yogyakarta is rational.

Effectiveness of web based educational on improving knowledge of acne vulgaris self medication among senior high school students Lolita Lolita; Ni Putu Isabela Meita Putri
Pharmaciana Vol 7, No 2 (2017): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The presence of technology canÂ provide realÂ alternativesÂ to build knowledge in delivering health education materials. The aim of this study was to investigate if web-based education methods may rising a studentâ€™s knowledge about self medication of acne. This research using an experimental pretest-posttest control group design while the sampling technique using convenience nonprobability sampling. Inclusion criteria for participants were senior high school students aged 13-19 years, active social media users, and willing to fill out the research questionnaire. Participants were allocated to the exclusion criteria as students who perform routine skin care in the acne treatment. Control group consisted of 62 respondents who were given face to face education and treatment group consisted of 62 respondents who were given website-based education. Data analysis were performed with a student t-test to assess the effect of educational intervention on studentâ€™s knowledge. The independent t-test showed there was a significant increase of knowledge between the control and the treatment groupsÂ Â (p = 0,000) with 95% confidence level. This study demonstrate that web-based educational intervention had a significant increase on the studentâ€™s knowledge about acne vulgaris self medication.

SINTESIS TURUNAN ASETOFENON DARI 1-(4-ASETOKSIFENIL-3-METOKSI)-2-PROPANIL FORMAT Kusmiyati Kusmiyati; Sabirin Matsjeh; Jumina Jumina
Pharmaciana Vol 2, No 1 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The Synthesis of acetophenone derivative from 1-(4-acetoxyphenyl-3-methoxy)-2-propanyl formate through Fries Rearrangement in order to produceortho hidroxy acetophenone derivative as starting material of Flavanoid compound hasbeen done. The reaction of 1-(4-acetoxyphenyl-3-methoxy)-2-propanyl formate wasdone by heating at 120 Â°C for 3 hours under AlCl3, dichloromethane as the catalyst andsolvent, respectively. The structure of the compound was identified using Infra Redspectrometry (IR) dan GC-MS. Fries rearrangement of 1-(4-acetoxyphenil-3-methoxy)-2-propanyl formate produce 1-(2-hyidroxy-3-methoxy-5-propenyl)-acetophenone and 1-(2-hyidroxy-3-methoxy-5-propanyl)-acetophenone as sideproduct with product rendemen were 43.26% and 9.48%, respectively.

Curcumin encapsulation using dendrimer PAMAM G4 conjugated with polyethylene glycol to improve the properties of gel dossage form Rahmah Elfiyani; Yudi Srifiana; Faisal Dharojat Al Rasyied
Pharmaciana Vol 8, No 1 (2018): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Curcumin had a low bioavailability, to improve it than curcumin was encapsulated in the PAMAM dendrimer conjugated PEG. To facilitate topical use, curcumin dendrimer was combined with a carbomer 940 that can produce hydration conditions in the stratum corneum so as to increase the bioavailability of curcumin. This study aimed to obtain the ratio between curcumin with dendrimer of PAMAM G4: PEG in the formation of curcumin dendrimer combined in the base of carbomer 940 to produce the optimal of physical characteristics of dendrimer and physical stability of gel. The study was conducted by conjugating PAMAM G4 with PEG with a ratio of 1:5, and then encapsulated curcumin in dendrimer with a ratio of 1:0.2 (F1); 1:0.02 (F2) and 1:0.002 (F3). Further dendrimers that have encapsulated curcumin were formulated in a gel with a carbopol base 940. The physical characteristics of the gel tested were polydispersity index, zeta potential and particle size, organoleptic, flow properties, and pH at weeks 0, 2, 4 and 6. The results shows that F1 has zeta potential highest and the lowest viscosity of the other formula, while F3 has the lowest potential zeta and highest viscosity of other formulas. In addition, the polydispersity index, particle size, organoleptic, flow properties and pH; there are not a significant difference in each formula, but the particle size, zeta potential, and viscosity of gel can decrease with longer storage time. Conclusion of this study that the ratio between curcumin and dendrimer PAMAM G4:PEG of 1: 0.2 shows the optimal of physical characteristics of dendrimer and physical stability of gel.

Page 33 of 81 | Total Record : 808

31 32 33 34 35

Filter by Year

2011 2025

Filter By Issues

All Issue Vol. 15 No. 3 (2025): Pharmaciana Vol. 15 No. 2 (2025): Pharmaciana Vol. 15 No. 1 (2025): Pharmaciana Vol. 14 No. 3 (2024): Pharmaciana Vol. 14 No. 2 (2024): Pharmaciana Vol. 14 No. 1 (2024): Pharmaciana Vol 14, No 1 (2024): Pharmaciana Vol 13, No 3 (2023): Pharmaciana Vol. 13 No. 3 (2023): Pharmaciana Vol 13, No 2 (2023): Pharmaciana Vol 13, No 1 (2023): Pharmaciana Vol 12, No 3 (2022): Pharmaciana Vol 12, No 2 (2022): Pharmaciana Vol 12, No 1 (2022): Pharmaciana Vol 11, No 3 (2021): Pharmaciana Vol 11, No 2 (2021): Pharmaciana Vol 11, No 1 (2021): Pharmaciana Vol 10, No 3 (2020): Pharmaciana Vol 10, No 2 (2020): Pharmaciana Vol 10, No 1 (2020): Pharmaciana Vol 9, No 2 (2019): Pharmaciana Vol 9, No 1 (2019): Pharmaciana Vol 8, No 2 (2018): Pharmaciana Vol. 8 No. 2 (2018): Pharmaciana Vol 8, No 2 (2018): Pharmaciana Vol 8, No 1 (2018): Pharmaciana Vol 8, No 1 (2018): Pharmaciana Vol 7, No 2 (2017): Pharmaciana Vol 7, No 2 (2017): Pharmaciana Vol 7, No 1 (2017): Pharmaciana Vol 7, No 1 (2017): Pharmaciana Vol 6, No 2 (2016): Pharmaciana Vol 6, No 2 (2016): Pharmaciana Vol 6, No 1 (2016): Pharmaciana Vol 6, No 1 (2016): Pharmaciana Vol 5, No 1 (2015): Pharmaciana Vol 5 No 1, 2015 Vol 5, No 2 (2015): Pharmaciana Vol 5, No 2 (2015): Pharmaciana Vol 5, No 1 (2015): Pharmaciana Vol 5, No 1 (2015): Pharmaciana Vol 4, No 2 (2014): Pharmaciana Vol 4, No 2 (2014): Pharmaciana Vol. 4 No. 2 (2014): Pharmaciana Vol 4, No 1 (2014): Pharmaciana Vol 4, No 1 (2014): Pharmaciana Vol 3, No 2 (2013): Pharmaciana Vol 3, No 2 (2013): Pharmaciana Vol 3, No 1 (2013): Pharmaciana Vol 3, No 1: Mei 2013 Vol 3, No 1 (2013): Pharmaciana Vol 2, No 2 (2012): Pharmaciana Vol 2, No 2: November 2012 Vol 2, No 2 (2012): Pharmaciana Vol 2, No 1: Mei 2012 Vol 2, No 1 (2012): Pharmaciana Vol 2, No 1 (2012): Pharmaciana Vol 1, No 2: November 2011 Vol 1, No 2 (2011): Pharmaciana Vol 1, No 2 (2011): Pharmaciana Vol 1, No 1 (2011): Pharmaciana Vol 1, No 1 (2011): Pharmaciana Vol 1, No 1: Mei 2011 More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Muhammad Syahrir

Contact Email
m.syahrir7406@unm.ac.id

Phone
-

Journal Mail Official
nurkhasanah@pharm.uad.ac.id

Editorial Address
Jl. Prof. Dr. Soepomo, S.H., Janturan, Warungboto, Umbulharjo, Yogyakarta, Indonesia Kode pos 55164

Location
Kota yogyakarta,

Daerah istimewa yogyakarta

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Muhammad Syahrir

Contact Email m.syahrir7406@unm.ac.id

Phone -

Journal Mail Official nurkhasanah@pharm.uad.ac.id

Editorial Address Jl. Prof. Dr. Soepomo, S.H., Janturan, Warungboto, Umbulharjo, Yogyakarta, Indonesia Kode pos 55164

Location Kota yogyakarta, Daerah istimewa yogyakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Muhammad Syahrir

Contact Email
m.syahrir7406@unm.ac.id

Phone
-

Journal Mail Official
nurkhasanah@pharm.uad.ac.id

Editorial Address
Jl. Prof. Dr. Soepomo, S.H., Janturan, Warungboto, Umbulharjo, Yogyakarta, Indonesia Kode pos 55164

Location
Kota yogyakarta,

Daerah istimewa yogyakarta

INDONESIA