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Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
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Articles 1,078 Documents
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Malnutrition-Inflammation Score (MIS) and Physical Activity among Hemodialysis Patients in Dr. Hasan Sadikin General Hospital Bandung Hamuktiono, Rizka Putri; Supriyadi, Rudi; Suraya, Nida
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Protein Energy Malnutrition (PEM) related to inflammation and physical activities reduction occur commonly among hemodialysis patients. This study aimed to describe Malnutrition-Inflammation Score (MIS) and physical activity of hemodialysis patients.Methods: This study involved 117 patients in the Hemodialysis Unit of Dr. Hasan Sadikin General Hospital Bandung from September to October 2014. Secondary data were collected to examine MIS and physical activity, which was measured by using Baecke Physical Activity Questionnaire. The collected data were presented using frequency distribution.Results: Eighty (68.4%) patients had MIS <6, thirty seven (31.6%) patients had MIS ≥6, and ninety four (80.3%) patients had light physical activity.Conclusions: Most of the patients have MIS <6 and are physically inactive. [AMJ.2015;2(4):601–7] DOI: 10.15850/amj.v2n4.478
The Relationship of Age, Parity and Body Mass Index as Risk Factors to the Incidence of Uterine Myoma in Dr. Hasan Sadikin General Hospital Ilma, Nurul; Tjahyadi, Dian; Judistiani, Tina Dewi
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Uterine myoma is a benign gynecological tumor which is commonly occurred in women. The incidence of uterine myoma in the world is 20–35% while in Indonesia is about 2.4–11.7%. Age, parity, and body mass index are correlated with the incidence of uterine myoma. This study aimed to determine the relationship among those factors towards uterine myoma, and to identify the prognostic value of body mass index in order to prevent uterine myoma.Methods: A case-control study was conducted to examine 394 medical records of patients with uterine myoma at Department of Obstetrics and Gynecology Dr. Hasan Sadikin General Hospital Bandung from 2006 to 2011.  The case group were 133 and the control group were 261. The data were the subject’s weight, height, age, and parity. The correlation among all variable and the occurrence of uterine myomas were conducted using multiple logistic regression analysis.Results: There was no different range of age between the two groups. The incidence rate ratio of parity was 2.254 (95% confidence interval:1.310–3.876), followed by body mass index>33.0 incidence rate ratio was 1.691 (95% confidence interval: 0.477–5.994). From the receiver operating characteristic curve, it could be seen that the cut-off points for body mass index was 20.44 kg/m², and the risk of uterine myomas scaled up as the increase of body mass index.Conclusions: Parity and BMI can affect the risk of uterine myomas. To prevent the incident of uterine myomas, parity must be limited and BMI must be below the cut-off points (20.44 kg/m²). DOI: 10.15850/amj.v2n3.485
Distribution of Cartilage Neoplasm based on Histopathological Types at Dr. Hasan Sadikin General Hospital Bandung Period 2008–2012 Anggraini, Desy; Yantisetiasti, Anglita; Ismono, Darmadji
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Cartilage neoplasms are less common compared to other neoplasms. Its incidence is 22% among all the musculoskeletal neoplasms. Despite many other studies about patient characteristics of theneoplasm in other regions, descriptive data in Bandung city is still unknown. The objective of this study is to determine the distribution of both benign and malignant neoplasms based on their characteristics of histopathological type, gender, age and anatomical site.Methods: The subjects of this descriptive study were taken from the medical records of the patients who had been examined histopathologically in Anatomical Pathology Department at Dr. Hasan Sadikin General Hospital Bandung, Indonesia within the period of 2008 to2012. The sample was obtained using total sampling technique. Patients diagnosed with cartilage neoplasms were included whereas incomplete medical records were excluded. Histopathological type, gender, age and anatomical site of each patients were collected and analyzed.Results: Seventy cartilage neoplasm cases were found. The distribution of cases comprised of 48 (67%) benign and 23 (33%) malignant. The most common benign neoplasm was osteochondroma and chondroma. Benign neoplasms were more prevalent among men and patients <30 years old, while malignant neoplasm was prevalent among women and patients >60 years old. Femur was the most common site for all neoplasms except for chondroma.Conclusions: PThere are differences in characteristic of benign and malignant cartilage neoplasm patients. Both benign and malignant cartilage neoplasms showed differences on the distribution of patient characteristics. [AMJ.2015;2(4):561–7] DOI: 10.15850/amj.v2n4.641
Propolis as an Anti-allergy Based on Decrease in Total Eosinophil Count in Rat Models Nambiar, Rashmika; Rohmawaty, Enny; Lismayanti, Leni
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Propolis is a natural herb derived from plant resins by bees. Propolis contains flavonoids that act as anti-allergy. The composition of flavonoids in propolis varies according to each region like Brazilian, Chinese, Malaysian and Indonesian propolis due to differences in medicinal plants in that area. The aim of this study is to determine the effect of propolis as an anti-allergy and to determine which is the most effective among propolis of Brazilian, Malaysian and Indonesian origin.Methods: An experimental study was performed on 28 Wistar male rats divided into four groups, Brazilian, Malaysian, Indonesian propolis and a negative control group. The used parameter was decreased in total eosinophil count in ovalbumin induced allergy in rats. Propolis or aquadest as control were given orally 0.25ml once daily.Results: All three groups of propolis showed statistically significant results (p<0.05), in decreasing eosinophil count. However, Malaysian and Brazilian propolis showed much more significant effects compared to that of Indonesian propolis. This could be due to the difference in composition and concentration of flavonoids in Indonesian propolis compared to the Brazilian and Malaysian propolis.Conclusion: Propolis has a significant effect as an anti-allergy. Malaysian and Brazilian propolis are more effective as an anti-allergy compare to Indonesian propolis. Propolis can thus be used as an alternative treatment for allergy. [AMJ.2015;2(1):208–12]
Barriers to Smoking Cessation among Medical Students 2012–2013 Academic Year in the Faculty of Medicine, Universitas Padjadjaran Kathrine, Reni Yuditha; Setiawati, Elsa Pudji; Saputra, Lucky
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Smoking is one of leading various diseases and even death globally.  It is often difficult for smokers to stop smoking, even those who work as a medical professional because there are some barriers around them. The objective of this study was to get an overview of the barriers to smoking cessation among smoker students of Faculty of Medicine, Universitas Padjadjaran.Methods: A descriptive study was carried out to 62 medical students 2012–2013 academic year in the Faculty of Medicine, Universitas Padjadjaran. Before the respondents were selected, a survey using questionnaire was conducted to all medical students from the same academic year to determine their smoking status. A set of questions was developed, consisted of 4 components: physical or social, psychological or emotional, accessibility, and social contextual/life circumstances barriers to smoking cessation. The collected data were analyzed and presented in the form of percentages shown in the tables and figures.Results: The most frequent barriers were from physical or social barriers (friends who smoke, 85%), psychological or emotional barriers (fear of losing enjoyment, 71%), barrier to access (lack of information about the way of smoking cessation, 42%) and social contextual/life circumstances barriers (having other priorities other than to stop smoking, 71%).Conclusions: There are some barriers in medical students smokers make them difficult to stop smoking although they have more knowledge about health and the impact of smoking on health than other people. DOI: 10.15850/amj.v2n3.561
Comorbidity among Hospitalized Patients with Chronic Obstructive Pulmonary Disease in a Teaching Hospital, West Java Indonesia Aini, Dini Qurrotu; Suryadinata, Hendarsyah; Herdiningrat, R. B. Soeherman
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: One of the most important causes that can increase the risk of hospitalization and death in  chronic obstructive pulmonary disease is comorbidity. The aim of this study was to identify the proportion of comorbidity among hospitalized patients with chronic obstructive pulmonary disease in a teaching hospital, West Java, Indonesia, from January to December 2012.Methods: A descriptive study was conducted from  September to November 2013 in Internal Medicine Department of Dr. Hasan Sadikin General Hospital Bandung. The study used 107 medical records that consisted of data about patients with chronic obstructive pulmonary disease (COPD) who were hospitalized between January to December 2012. The medical records were collected using simple random sampling. Variables identified in this study were characteristics of the patients (age, sex, and smoking history) and comorbidity events. Comorbidity events were coronary artery disease (CAD), lung cancer, diabetes mellitus (DM) type 2, anemia, dyslipidemia, osteoporosis, depression, pulmonary artery hypertension (PAH), andhypertension. Age variable was divided into 3 categories with interval 20 years. All collected data were presented in frequency distribution.Results: Most of the patients in this study were 50–69  years old, male, and had smoking history. The highest proportion of comorbid condition was hypertension, followed by anemia and coronary artery disease.Conclusions: Patients with COPD have one or more other diseases (comorbidity). Three most frequent comorbidities are hypertension, anemia, and coronary artery disease. [AMJ.2015;2(4):485–91] DOI: 10.15850/amj.v2n4.632
Clinical Profile and Mortality in Children with Pneumonia Manivel, Ashvinii; Sudarwati, Sri; Herdiningrat, RB. Soeherman
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Pneumonia is the leading killer in under-five children. Therefore, by identifying the danger signs, we are able to predict children who are at higher risk of mortality. The objective of the study is to identify the relationship between the clinical profile and mortality in children with pneumonia at Dr. Hasan Sadikin General Hospital, Bandung.Methods: This was an analytical study with a retrospective case control approach using medical records with patient’s age limitation of 1–60 month. The study period started on January 1st 2010 and ended on December 31st 2011. All types of pneumonia included whereas congenital anomalies, immunocompromised and Down’s syndrome patients were excluded in this study. Data were presented as frequency distribution.Results: During the study period, there were 653 children under age of 5 with pneumonia. Only 56 subjects met the inclusion and exclusion criteria. Twenty-eight patients with pneumonia were cured and 28 died. Based on the phi’s coefficient, tachycardia (α-value = 0.019) and hepatomegaly (α-value = 0.001) were significant predictors of death and based on the Mantel-Haenszel analysis, hepatomegaly (OR=9.62, CI 95% 2.349–39.35) was significant as a risk for mortality. Inability to drink, cyanosis, tachypnea, grunting, vomiting, convulsion, and unconsciousness were not related to mortality.Conclusion: Tachycardia and hepatomegaly have a significant relationship with mortality in under-five children with pneumonia. [AMJ.2015;2(1):235–40]
Factors Affecting Mortality in Adult Tetanus Patients Khrisnan, Lohghinee; Ong, Anam; Panigoro, Ramdan
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Tetanus is a devastating disease that is associated with high mortality. The aim of this study was to analyze the prognostic factors that were associated with high mortality in tetanus. Methods: This was an analytical study and the data was collected retrospectively from 1 January 2010–31October 2012 in the Department of Neurology, Dr. Hasan Sadikin General Hospital.Results: Out of hundred thirty two cases only 87 cases of tetanus patient have complete medical records. There were 54 male and 33 female. The age range was 35-49 years old. Mortality rate was high (32.18%). The most frequent wound site is extremities (85.07 %). The absence of post-injury tetanus vaccination was 75.86%, period of onset <48 hours was 67.82% and the use of mechanical ventilation and tracheostomy 36.07%. Mortality was significantly associated with an incubation period <7 days (p<0.05), presence of fever(p <0.05), co morbidity of autonomic storm (p<0.01), and the severity of the disease by grade 5 (p<0.05).Conclusions: Factors affecting the mortality in adult tetanus patients were significant for incubation period, fever, co morbidity and severity of the disease by grade. [AMJ.2015;2(1):157–61]
Clinical Characteristic and Outcome of Acute Lower Respiratory Tract Infection in Children with Congenital Heart Disease Gabriela, Krystle; Kuswiyanto, Rahmat Budi; Dwiyatnaningrum, Fenny
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Acute Lower Respiratory Tract Infection (ALRTI) is the leading cause of deaths in children under 5 years of age worldwide, and has high morbidity and mortality in children with Congenital Heart Disease (CHD). The objective of this study was to obtain the incidence, clinical characteristic, and outcome of ALRTI children with CHD.Methods: A retrospective hospital-based study was conducted from January 2007–December 2011 to medical record of child patients with ALRTI and CHD in the Department of Child Health of Dr. Hasan Sadikin General Hospital, Bandung. The diagnosis of CHD was determined by echocardiography. The collected data was analyzed and presented in percentage shown in tables.Results : From 3,897 children who had ALRTI, there were 149 children with CHD (3.8%), with 11.4% of whom founded with recurrent episodes. This happened often in girls than boys with quite similar ratio of 1.37: 1.The majority of children (80%) was under 1 year old of age, 72.5% with malnutrition, and 24.8% with severe malnutrition. Clinical symptoms mostly found were difficulty of breathing (98%), fever (85.2%), cough (75.2%), and runny nose (63.1%). The most common types of CHD were Patent Ductus Arteriosus (47.6%), followed by Ventricular Septal Defect (47%). Bronchopneumonia (86.6%) was the common type of ALRTI. The length of stay was mostly less than 10 days (70.5%). From all the children 43.7% had complications, and 6.7% died.Conclusions: The ALRTI in children with CHD is not common and has good outcome. The majority for CHD lesions are Patent Ductus Arteriosus and Ventricular Septal Defect while for ALRTI is Bronchopneumonia. DOI: 10.15850/amj.v2n3.483
Enteropathogenic Bacteria from Padang Food in Jatinangor September–October 2012 Husain, Syed Anwar; Sudigdoadi, Sunarjati; Firmansyah W., Abdullah
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Diarrhea is a food borne disease and still a major health problem in Indonesia. Padang foodis a popular cuisine and is exposed on an opened display, sometimes for many hours in room temperature,catering favorable conditions for bacterial growth. This study is undertaken to identify enteropathogenicbacteria on food in Padang restaurants located in Jatinangor, SumedangMethods: A laboratory study was conducted in the microbiology laboratory of the Department ofMicrobiology in the Faculty of Medicine, Universitas Padjadjaran, during September–October 2012. Sampleswere collected from 5 Padang restaurants located in Jatinangor using systematic random sampling. Fromeach restaurant, 4 wet samples were collected approximately 2–4 hours after being left open on the display shelves from sambal hijau, sambal merah, gulai babat and gulai nangka, cultured in tryptic soy broth (TSB) and incubated for 24 hours at 37 ºC, then inoculated in Mac Conkey agar and incubated for 24 hours at 37 ºC. Gram-staining was performed to identify gram-negative rods. The bacteria were put through biochemical tests.Results: Four species bacteria from the Enterobacteriaceae family were identified. The most frequent bacteria which was identified in the samples was Shigella sp (4 from 20), followed by Klebsiella pneumonia(3 from 20), Escherichia coli and Pseudomonas sp were less identified.Conclusions: Various Padang foods have potential risks of bacterial contamination due to the preparation,handling, and serving. It should be considered that the prepared food should be covered and placed in foodwarmers, ensuring warm food for hours. [AMJ.2015;2(1):241–44]

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