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Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
Arjuna Subject : -
Articles 1,068 Documents
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Comparison of Cognitive Function of Ischemic Stroke Patients with and without Pneumonia Amanda Diannisa Azzahra; Lisda Amalia; Chandra Calista; Sofiati Dian; Siti Aminah; Paulus Anam Ong
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2356

Abstract

Background: Pneumonia is a common complication of ischemic stroke that may worsens brain injury, leading to cognitive impairment as well as patient outcome. The aim of this study was to compare cognitive function in ischemic stroke patients with and without pneumonia.Methods: This study was a comparative numerical analytic retrospective cross-sectional study that was conducted from September 2020 to February 2021. This study used data from ischemic stroke patients treated at Dr. Hasan Sadikin General Hospital in 2019 with the total sampling method. Data were stratified into patients with pneumonia and without pneumonia. The mini mental state examination (MMSE) was used to measure cognitive function in both groups and  scores were compared using the Mann-Whitney Test.Result: Of the 164 data, 25 were patients with pneumonia and 139 without pneumonia. Male patients were predominantly prevalent in the pneumonia and non-pneumonia groups. Hemiparesis was the most common neurological deficit. The MMSE score was significantly lower in the pneumonia group (22.6 ± 5.4 vs. 24.7 ± 4.8, respectively; p-value=0.032). Conclusion: Cognitive function is more prevalent in ischemic stroke patient with pneumonia compared to non-pneumonia. However, other factors such as recurrent stroke and possible vascular risk factors should be considered for future studies to better identify the relationship between ischemic stroke and pneumonia.
Risk Factors for Febrile Seizures in Children Aged 6 – 59 Months in Surabaya, East Java Febrianto Adi Husodo; Sitti Radhiah; Pramita Anindya Nugraheni
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2351

Abstract

Background: Febrile seizures are common in children under 5 years of age. Parents are concerned when their children have seizures; therefore, it is necessary to provide promotive and preventive education regarding the risk factors for febrile seizures so that parents are more prepared. This study aimed to explore the risk factors for febrile seizures in children.Methods: This case-control study was conducted on 170 children. Sampling was carried out by purposive sampling on inpatients and/or outpatients at the Pediatric Department Dr. Ramelan Naval Hospital Surabaya during May 2019-July 2020. Secondary data for children with fever were retrieved from medical records, with seizures (n85) and without seizures (n85) as a control group. Furthermore, data on temperature, age, birth weight, and history of asphyxia were analyzed and compared, using the chi-square test or Fisher’s exact test.Results: There was a significant difference between the case and control groups regarding the history of asphyxia and the occurrence of febrile seizures (p=0.002; OR=26.39; and 95% CI 1.52-455.62). There was no significant difference between the risk factors for high temperature (p=0.12), age (p=0.52), or birth weight (p=0.37) with the occurrence of febrile seizures.Conclusions: A history of asphyxia in children under five years is a risk factor for febrile seizures. Appropriate education from health professionals can help parents improve their knowledge, attitudes, and practices in dealing with febrile seizures and their risk factors.
Psychosocial Burden Due to Acne Vulgaris Affects Treatment-Seeking Behavior in Medical Students in Jakarta, Indonesia Franklind Matthew; Regina Regina; Inneke Jane Hidajat; Melyawati Melyawati
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2179

Abstract

Background: Acne vulgaris (AV) is a chronic inflammation of the pilosebaceous unit of the skin that occurs in 85% of adolescents and can continue into adulthood. The skin of the facial area has an essential role in socializing, therefore, facial AV can contribute to the accumulation of psychosocial stress. The prevalence of individuals with AV seeking treatments is low in some countries. This study aimed to determine the association between psychosocial burdens due to AV and medical treatment-seeking behavior in young adults. Methods: A cross-sectional study was conducted in February 2020 among 100 medical students with AV. The ASEAN Lehmann criteria were used to objectively assessed AV. Psychosocial burden was determined by the Cardiff Acne Disability Index (CADI) questionnaire and then classified into unaffected (score 0), mild (score 1-5), moderate (6-10), and severe (11-15). History-related AV was obtained through a questionnaire. The analysis was performed using the chi-square test.Results: Of the 100 medical students with AV, 82% had suffered from mild to severe psychosocial burdens. The mean score of the CADI was 4.03. However, only 44% of students sought treatment from doctors for their AV. There was a significant association between psychosocial burden and medical treatment-seeking behavior (p = 0.014).Conclusion: The psychosocial burden of acne vulgaris in young adults is high, however, medical treatment-seeking behavior is low. Therefore, psychosocial management is an essential aspect in treating patients with AV.
Human Papillomavirus Infection and Awareness of Human Pappillomavirus Vaccines among Various Ethnicities in Libya Salma Korbag; Issa Korbag
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2250

Abstract

Background: Human papillomavirus (HPV) plays a role in increasing the risk of cervical cancer and other cancers. This study aimed to explore the incidence of HPV infection among various ethnicities in Libya. Furthermore, awareness and knowledge of HPV vaccines in the community were explored.Methods: A descriptive study was conducted to present HPV infection among cancer cases using the National Cancer Registry of Libya year 2011-2020, including gender, skin color, and ethnicity. Furthermore, awareness and knowledge of the HPV vaccines were assessed using questionnaires distributed through social media. Data were presented in percentage.Results: In total, there were 33,526 (58.1%) infected HPV-related cancers out of 57,620 cancer cases, of whom 25,296 (75.4%) were women and 8,230 (24.6%) were men. Based on cancer sites, the incidence of HPV-related cancers among whites was higher (>63% and more) than blacks except for anal cancer, of which blacks had a slightly higher incidence (54%) in females and 57% in males). Based on ethnicity, native Libyans such as Tabu, Touareg, and Berbers had different cancer sites. Moreover, the knowledge and awareness about HPV and related cancers were very poor among the population in Libya.Conclusions: Although HPV cancers represent a high percentage of cancer burdens among Libyans, awareness and knowledge on HPV and related cancer are lacking. Better education and provision of the HPV vaccines for future generations may eliminate and reduce HPV-related cancers.
Pathological Findings of the Lung at Neonatal Autopsy in Dr. Hasan Sadikin General Hospital Bandung Period 2016-2019 Rania Azzahra Salsazayasya Parikesit; Nita Novita; Hermin Aminah Usman
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2337

Abstract

Background: Infanticide is a criminal act when a mother kills her child at or soon after birth. Considering whether a case has been decided as infanticide, determination of the life of the neonate at birth is imperative. Breath signs from macroscopic and microscopic approacesh and hydrostatic test are useful indicators. This study aimed to explore the lungs pathological findings at autopsy of neonates.Methods: This study was a retrospective descriptive observational study, using medical records of neonatal deaths in the Department of Forensics and Medicolegal Dr. Hasan Sadikin General Hospital, Bandung for the period 2016–2019. Total sampling method was used. Inclusion criteria were neonatal death with presumptive infanticide, had autopsied and microscopic examination as well as neonatal death without putrefaction. Data on macroscopic and microscopic findings as well as the hydrostatic test were presented.Result: In total, 12 of the 42 medical records with data on presumptive infanticide met the inclusion criteria. For macroscopic findings, 7 of the 12 samples had positive results, meaning the lungs had sign of breath. Meanwhile, in microscopic findings 8 of the 12 samples had positive results. For the hydrostatic test, 8 out of 12 samples had positive results. Of the 12 samples, there were four samples that had different results, at least on one variable. Conclusions: Most of the cases are matched with macroscopic, microscopic, and hydrostatic test, but some unmatched data are also found. In order to improve reliability, especially for legal purposes in infanticide, it is necessary to conduct all the examination.
IgG levels in Human Papillomavirus Infection Associated with Clinical Stage of Head and Neck Squamous Cell Carcinoma Yussy Afriani Dewi; Agung Dinasti Permana; Fanny Yudhiono
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2171

Abstract

Background: Head and neck squamous cell carcinoma (HNSCC) is an invasive neoplasm of epithelial tissue in the head and neck and one of the etiologies of HNSCC is human papillomavirus (HPV) which maybe associated with the clinical stage of HNSCC. HPV infection in squamous cell epithelium produces specific IgG antibodies against HPV. IgG titer of HPV can help identify patients who are at risk for HPV-related cancers. This study aimed to explore the association between IgG titer of HPV with the clinical stages of HNSCC.Methods: The design of this study was analytic cross sectional, conducted at the Outpatient Clinic of Otorhinolaryngology-Head and Neck Surgery, Division of Oncology, Dr. Hasan Sadikin General Hospital Bandung period September-December 2017. Patients with HNSCC were recruited, and history was taken. Furthermore, histopathologic examination and HPV IgG serology examination was performed using the ELISA method. The HPV IgG levels were compared by stage and data were analyzed using the Shapiro Wilks test and Unpaired T test.Result: The HPV IgG was high in 75% (n=21) of HNSCC patients in the advanced stage and low in 25% (n=7) of patients in the early stage. There was  a significant relationship between HPV IgG titer and early and advanced stage of  HNSCC (p=0.001).Conclusion: The HPV IgG titer is related to the clinical stage of HNSCC indicating that the higher the HPV IgG level, the more advanced the clinical stage. Further study is needed to explore HPV IgG levels as a prognostic marker in HNSCC.
Characteristics of Neonates with Hyperbilirubinemia in Cileunyi, West Java Muhammad Rizki Fonna; Nia Kania; Gita Tiara Dewi Nasution
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2328

Abstract

Background: Neonates are prone to hyperbilirubinemia or jaundice due to the immaturity of various organ systems and complications at birth.  Immature organ systems occur primarily in preterm babies and babies with low birth weight (LBW).  The incidence of hyperbilirubinemia is about 60% among term neonates and is higher in preterm neonates. This study aimed to determine the characteristics of neonates with hyperbilirubinemia.Methods: This study used a cross sectional research design. Samples were obtained from medical records of neonates with hyperbilirubinemia throughout 2019 at Annisa Medical Center Hospital, Bandung Regency. Data on neonates that met the inclusion criteria were selected, including gender, gestational age, birth weight, mode of delivery, bilirubin levels (before and after phototherapy), and duration of treatment. Data analysis was performed using univariate statistical calculations.Results: From 786 data obtained, the prevalence rate of hyperbilirubinemia was 21.2%. Male neonates with hyperbilirubinemia were predominantly prevalent (n=103; 61.7%); whereas preterm neonates accounted for 51.5% (n=86), normal weight (85.6%), and born through vaginal delivery (n=116; 69.5%). After treatment, total bilirubin levels decreased, with the percentage of the >10 mg/dL group decreasing from 97.0% to 10.2%.  The average duration of treatment for neonates with hyperbilirubinemia was 4.4 days, however, the neonates who were treated less than the average were 71.3%.Conclusion: Preterm male is predominantly prevalent among neonates with hyperbilirubinemia, although they have conformed birth weight and vaginal delivery mode. The duration of treatment for neonates with hyperbilirubinemia mostly does not exceed 4 days, as long as the treatment reduces the total bilirubin level. Good therapeutic management in the first week of hyperbilirubinemia neonates is required.
Clinical Manifestations and Laboratory Examination Findings of Hepatocellular Carcinoma at a Tertiary Care Facility in Bandung: An Annual Observation Study Grace Amanda Maharani; Eka Surya Nugraha; Adhi Kristianto Sugianli
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2333

Abstract

Background: Hepatocellular Carcinoma (HCC) is the most prevalent liver cancer with high mortality. Early detection is important for better patient outcomes. The aim of this study was to explore clinical manifestations and laboratory examinations among HCC patients in a tertiary care facility.Methods: This was a cross-sectional descriptive study with a total sampling method, reviewing the medical record of patients with HCC in the Outpatient Clinic of Dr. Hasan Sadikin General Hospital between January to December 2019. Clinical manifestations, laboratory findings, and imaging results data were collected.Results: Of the 112 HCC patients included in this study, the HCC findings among new patients at the outpatient clinic were 8.4%, with hepatitis B (80.8%) as the major etiology. Complaints of abdominal pain (65.2%) was frequent. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were increased in 89.8% and 67% of patients, as well as total bilirubin levels in 58.8% of patients. In contrast, hemoglobin and albumin levels decreased in 55.3% and 78.1% of patients, respectively. The characteristics of tumor were mainly multinodular, with a size of 3-10 cm.Conclusions: The annual proportion of HCC in Dr. Hasan Sadikin General Hospital in 2019 is 8.4% among all outpatient gastrointestinal and hepatology cases, with hepatitis B as the most common etiology. Abdominal pain is the predominantly prevalent clinical manifestation with increased ALT and AST levels.
Visualization of Carotid Doppler in Patients with Ischemic Stroke at Dr. Hasan Sadikin General Hospital Bandung Year 2016-2019 Olivia Olivia; Ahmad Rizal Ganiem; Syarief Hidayat
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2285

Abstract

Background: Various pathological changes in both the intra and extracranial arteries that supply the brain can cause disturbance of cerebral blood flow and perfusion leading to cerebral dysfunction. Doppler ultrasound is able to assess these changes. This study was performed to evaluate the anatomical and physiological changes found in the carotid arteries of patients with ischemic stroke using Doppler ultrasound.Methods: The cross-sectional descriptive study design with total sampling method was conducted on the medical records of ischemic stroke patients who had carotid Doppler ultrasound at the Department of Cardiology and Vascular Medicine Dr. Hasan Sadikin General Hospital Bandung from 2016 to 2019. Demographic data, such as stroke diagnoses and plaque characteristics recorded in the Doppler reports were collected.Results: There were 38 data sets collected. The distribution and characteristics of atherosclerotic plaques were similar between the two carotid systems, with the same percentage of plaque being found in the right (31.6%) and left (36.8%) carotid system. The most common type of plaque found was type III and was located in the common carotid artery. Thrombus was absent in all patients. Intimal media thickening was found in 13.2% right system and 15.8% left system. Stenosis was present in 34.2% of patients, and most had <50% stenosis. Peak systolic velocity increased (>125 cm/s) in 5.3% of the right system and 7.9% of the left system of the internal carotid artery.Conclusions: Most of the atherothrombotic and thromboembolic type of ischemic stroke patients in this study have normal carotid Doppler ultrasound features. Further study on the presence of plaque in ischemic stroke patients in Indonesia is needed.
Implementation of Youth Information and Counseling Centers Related to HIV/AIDS Prevention in a Junior High School in Bandung Shifa Nadya Rahma; Insi Farisa Desy Arya; Rudi Wisaksana
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2252

Abstract

Background: Adolescents are the population group most at risk of HIV infection due to low knowledge about HIV/AIDS. The National Population and Family Planning Board (Badan Kependudukan dan Keluarga Berencana Nasional, BKKBN) has developed the Youth Information and Counseling Center (Pusat Informasi dan Konseling Remaja, PIK-R) Program as a forum for information and counseling services, one of which is about Adolescent Reproductive Health (ARH) including HIV/AIDS. This study aimed to explore whether the implementation of the programs related to HIV/AIDS prevention in adolescents, specifically in junior high school in Bandung City.Methods: A qualitative descriptive study was carried out at a junior high school in Bandung in August 2018. This study used a purposive sampling technique and data were collected by conducting in-depth interviews with nine program administrators who were then transcribed and coded based on the PIK-R management guidelines using the NVIVO12 software, observing the program activities and documentations study which were then triangulated.Results: Several indicators in the growing stage had been implemented  according to the guidelines, consisting of mastering ARH education materials including HIV/AIDS, conducting activities in the form of providing materials and peer counseling although without a secretariat room, and establishing networks and partnerships.Conclusion: The PIK-R program can be a media for preventing HIV/AIDS among junior high school students in Bandung regardless of resource limitations. Therefore, supports from BKKBN and the school itself is needed to improve the implementation of this program.

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