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Nexus Kedokteran Klinik
Published by Universitas Sebelas Maret
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 334 Documents
 2   3   4   5   6 
Hubungan Gagal Ginjal Kronik dengan Tebal Parenkim Ginjal pada Pemeriksaan USG Abdomen Fokus Ginjal Alfiani, Nur; Suyono, .; Balgis, .
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Complication that often occurs in chronic renal failure is the reduction of the kidney size. It widely associates with the thinning of the renal cortex due to pathological process. Unlike the cortex, the pathological process which occurred in renal medulla in chronic renal failure has not fully understood yet. Not many studies have examined the association of chronic renal failure with renal parenchyma overall. Therefore, this study aimed to determine the relationship of chronic renal failure with renal parenchyma width on abdomen USG renal focus. Method: This study was an analytical observational research with cross-sectional approach. Sample were taken using fixed-exposure sampling. Sample consisted of 30 subjects were divided into two groups, chronic renal failure and non chronic renal failure. Samples were then measured for renal parenchyma width using abdomen USG renal focus. The data were analyzed with independent-sample t test. In addition, to control confounding factor that could affect renal parenchyma width, age was selected to be controlled using multiple linear regression analysis. All of the data were analyzed using SPSS 17.0 for windows. Result: Patients with chronic renal failure had renal parenchyma width 7.92±2.57 mm (p = 0.001), while patients non chronic renal failure had renal parenchyma width 15.64±1.85 mm ( p = 0.001). Furthermore, based on the calculation, the multiple linear regression analysis showed the model equation Y = 16.78 – 7.95 X1 – 1.72 X2. The coefficient of determination (R2) of the regression analysis obtained a value of 0.781 means that 78.1% variation in the parenchyma width (Y) can be explained by variations contained in the chronic renal failure (X1) and age ≥54 years old (X2), while 21.9% is explained by other variables not included in the model equations. Conclusion: This study reveals that there is significant correlation between chronic renal failure and renal parenchyma width (p < 0.05), where chronic renal failure patients have renal parenchyma width thinner than the non chronic renal failure patients. Keywords: Chronic Renal Failure, Renal Parenchyma Width, Age, abdomen USG 
Hubungan antara Hipoglikemi dengan Kejadian Hipotermi pada Neonatus Rujukan di RSUD Dr. Moewardi Virgiansari, Dio Dara; Hidayah, Dwi; Saptawati, Leli
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Neonatal hypoglycaemia is an avoidable cause of mortality and neurodevelopmental impairment. Hypoglicemia may develop to hypothermia as a result of metabolic thermogenesis disturbance. Hypothermia during the newborns period is widely regarded as a major contributory cause of significant morbidity and mortality in developing countries including Indonesia, about 7% prevalence of hypothermia has been reported happens on newborns.  The objective of this study was to determine the association between hypoglicemia and hypotermia in newborns. An analytic observational using cross sectional approach was used in this study. A total of eighty one newborns was selected by fixed-disease sampling. Sample of this study were the newborns who referred to Dr. Moewardi Hospital. The data were collected by the measurement of blood glucose concentration and axillary temperature of newborns. The data was analyzed using multiple logistic regression test on SPSS 16 for Windows. Hypoglycemic newborns have a risk of hypothermia 2.381 times higher than non hypoglicemic newborns after controlling some confounding factors, such as: age, birth weight, gestational age, and status of asphyxia, altough it was statistically not significant (OR = 1.98; CI = 95%; 0.54, 7.73; p = 0.305). Early neonatal age (0-7 days), low birth weight (< 2.500 gram), early gestational age (< 37 weeks), asphyxia status were also risk factors of hypothermia in newborns. There was a moderate association between hypoglicemia and hypothermia on referral newborns, altough it was statistically not significant. Hypoglycemic newborns have a higher risk of hypothermia than non hypoglicemic newborns after controlling some confounding factors, such as: age, birth weight, gestational age, and status of asphyxia. Keywords: newborns, referral, hypoglicemia, hypothermia
Efek Anestesi Inhalasi Sevofluran dan Isofluran Terhadap Frekuensi Nadi Fatimah, Aulia Nurul; Sudjito, Mulyo Hadi; Probandari, Ari
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Anesthesia is an important part of the surgery. Sevoflurane and isoflurane are two inhalation anesthesia drugs have been commonly used. During anesthesia, one of indicators should be monitored is frequency of pulse. This research aimed to know the effects of these two drugs to the frequency of pulse. Methods: This research was an analytical observational research with the approach of cross sectional. The sample was taken by consecutive sampling after being selected based on the inclusion and exclusion criteria. Totally, 50 patients were divided into two groups of inhalation anesthetic sevoflurane and inhalation anesthetic sevoflurane and isoflurane. Data was analyzed with independent t test. Results: The p values on t-independent test in the early phase of the pulse frequency, phase induction and phase intubation were 0.04; 0.00; 0.02, and of the phase 5’ of incision, 10’of incision and 15’of incision were 0.02; 0,0; 0.03. This results showed statistical significant of mean of pulse-frequency difference between sevoflurane and isoflurane in each of phase of inhalation anesthesia. Conclusions: Both sevoflurane and isoflurane influence the frequency of pulse. The mean of pulse frequency by isoflurane is higher than sevoflurane. However, inhalation anesthesia sevoflurane provides better stability than isoflurane. Keywords: Anesthetic Inhalation, Frequency of Pulse, Isoflurane, Sevoflurane
Hubungan Paparan Asap Rokok dengan Otitis Media Supuratif Kronik di RSUD Dr. Moewardi Dwi Mahanani, Dian Nastiti; Sudrajad, Hadi; ., Hartono
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: The association between exposure to cigarette smoke with chronic suppurative otitis media is still debated. Cigarette smoke reduce the function of cilia, resulting blockage of mucus in the Eustachian tube. Besides of that, cigarette smoke is also a stressor that can lead to decreased immune system. This situasion make organism easier to develop and entry into the middle ear. This study aimed to determine the association between exposure to cigarette smoke with chronic suppurative otitis media in RSUD Dr. Moewardi. Methods: This study was observational by using case control design. Research subjects are grouped into case and control groups. The sample was selected by purposive sampling with inclusion and exclusion criteria have been determined. Data is collected by questionnaire of smoking history and medical record data of patients. Data were analyzed using Chi Square test with SPSS 17.0 for Windows. Results: There was a significant association between exposure to cigarette smoke with chronic suppurative otitis media in RSUD Dr. Moewardi. Samples with a history of smoking had a risk of chronic suppurative otitis media 4, 5 times higher than without a history of smoking (p = 0, 028; OR = 4, 5). Conclusions: There is a association between exposure to cigarette smoke with chronic suppurative otitis media in RSUD Dr. Moewardi. Smoking cigarette can increase the risk of chronic suppurative otitis media. Keywords: exposure to cigarette smoke, Chronic suppurative otitis media.
Pengaruh Paparan Polusi Jalan Raya terhadap Waktu Transpor Mukosiliar Hidung Pada Petugas Kebersihan Dinas Kebersihan dan Pertamana Kota Surakarta Imaduddin, Muhammad Aji; Hendradewi, S; Nurcahyo, Vicky Eko
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Nasal health is strongly influenced by the nasal mucociliary transport system as the primary defense of exposure to hazardous substances contained in the air. Exposure to air pollution experienced daily by the janitor at the town highway would affect the nasal mucociliary clearance mechanisms. Exposure to pollution will cause mucosal can not move, therefore nasal mucociliary transport time will be longer than normal. Methods: This type of research is observational analytic cross-sectional approach. The sample was a janitor Cleanliness and Sanitation Department of Surakarta as many as 30 people. The control group is a cleaning service Hospital Dr. Moewardi as many as 30 people. Measuring instrument used was a questionnaire and saccharine test, then performed the data analysis by Chi Square analysis. Results: In this research, the influence of exposure to highway pollution on nasal mucociliary transport time. Janitor Cleanliness and Sanitation Department of Surakarta exposed pollution has six times the risk than cleaning service at the Hospital Dr. Moewardi not exposed to pollution in terms of prolongation of nasal mucociliary transport time. Conclusions: Based on the study, exposure to highway pollution prolong nasal mucociliary transport time. Keywords: Exposure to highway pollution, nasal mucociliary transport time
Hubungan antara Syok Berkepanjangan (Prolonged Shock) dengan Kematian Anak Penderita Dengue Shock Syndrome di PICU/NICU RSUD Dr.Moewardi Solehah, Rizka; Pudjiastuti, .; Saptawati, Leli
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Dengue Shock Syndrome (DSS) is severe type of dengue infection which is the major cause of mortality. In Indonesia, DSS cases increase until 53%, the number of incidence are 500.000 cases every year, and its mortality is 1-5%. DSS is caused by plasma leakage which can leading to tissue hypoperfusion. If proper and timely management of DSS had delayed, DSS may result in multiple organ dysfunction syndrome (MODS) even death. The purpose of this research is to find out whether there is the relationship between prolonged shock and mortality of children with Dengue Shock Syndrome at PICU/NICU of RSUD Dr. Moewardi. This was an analytic observational study with cross sectional approach and purposive sampling technique. A sample of 61 study subject was selected by purposive sampling technique from children who aged 0-18 years, children who suffered Dengue Shock Syndrome and treated at PICU/NICU RSUD Dr. Moewardi in June 2006 - December 2011. The data obtained from PICU/NICU and medical records section of RSUD Dr. Moewardi. Statistical analysis was using chi square test and continued by using contingency coefficient test. Patients of prolonged shock DSS have higher mortality than patients of non-prolonged shock DSS, although the relation between them is low (p = 0.005; contingency coefficient = 0,335). The mortality risk were five times greater (OR= 5; CI 95%; 1,536 – 16,273). In this study, DSS was much found in girl (59,02%), children aged 6-12 years old (52,46%), and usually who had weak condition (67,21%), and good nutritional status because this study was done at area with good nutritional status was majority in children. There were significant relationship between prolonged shock and mortality of children with Dengue Shock Syndrome at PICU/NICU of RSUD Dr. Moewardi with low rate relation. Patients with prolonged shock DSS have higher risk of mortality than patients with non-prolonged shock DSS.
Perbedaan Aktivitas Fisik pada Pasien Asma Terkontrol Sebagian dengan Tidak Terkontrol di RSUD Dr. Moewardi Dwimaswasti, Olivia; Harsini, .; Isdaryanto, .
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background:Asthma can interfere with the fulfillment of the needs and proven to reduce the productivity and quality of life for the sufferer. Although asthma rarely cause death, disease often cause problems in both children and adults. Asthma can cause interference with daily activities and emotional disorders (anxiety, depression). Asthma can be mild and do not interfere with daily activities but also be persistent and interfere with daily activities. This studyaimedto determine differencesof  physicalactivity between partlycontrolled andnotcontrolledasthma patient at theRSUDDr. Moewardi. Methods:This analytic study was observational using cross sectional approach. A sample of 60 study subjects was selected by purposive sampling from outpatients who visited Pulmonology Clinics, RSUD Dr. Moewardi Surakarta. The data was collected by interview and some datas taken from the medical records. The data was analyzed using logistic regression model on SPSS 17.00 for windows. Results:Inpartilycontrolledasthmawithlowphysical activity11 people(36.7%), moderate physicalactivity10people(33.3%) andhigh activity9people(30%). While in thenot controlledasthma with low activity24people(80%), moderate activity5 people(16.7%) and thehighactivity 1 person(3.3%).Differencesin physical activityin asthma patientspartlycontrolledand not controlledwithlowphysical activityx2=12.895, p= 0.002; OR=19.6(95% CI2.20up to174.72, p =0.008)and thedifferences inphysical activityin patientspartlycontrolledasthmaand not controlledwithmoderate physicalactivityx2=12.895, p= 0.002; OR=4.5 (CI 95%0.44up to46.17, p =0.205). Conclusions:There are differencesof  physicalactivity between partlycontrolled andnotcontrolledasthma patient. Keywords:asthma bronchiale, control asthma, physical activity
Hubungan Kecemasan Dengan Gangguan Siklus Menstruasi Pada Siswi Kelas XII Sma Negeri 1 Surakarta Damastuti, Anisa Febrina; Hidayati, Rosalia Sri; Suryawan, Arif
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background : The number of people who suffer anxiety was estimated to be 5% of population, with the ratio off women and men is 2:1. Emotional breakdown, tension, presure, and agitation could lead to disruption of menstrual cycle. The purpose of this study was to determine the correlation of anxiety and mestrual cycle disorder on grade XII female student of SMA Negeri 1 Surakarta. Methods : This study was an observational analytic with cross sectional study approach. The sampling technique used was purposive sampling. Sample was as many as 82 subjects, taken from the grade XII female students of SMA Negeri 1 Surakarta, and was hold on August 2012. Data were obtained by TMAS and menstrual cycle questionnaires. The statistical analysis used was chi-square. Results : Chi square calculation obtained X2 > X2 table = 7,142 > 3,841. The number showed a significant association. Conclusion : Based on this study it could be concluded that there was a positive relationship between anxiety and mestrual cycle disorder on grade XII female student of SMA Negeri 1 Surakarta. Keywords : anxiety, menstrual cycle, menstrual cycle disorder
Pengaruh Rehabilitasi Medik Terhadap Tingkat Stress Pasien Karsinoma Mammae Pasca Operasi Di RS Kanker Dharmais Ichwan, Hafidz Nur; Riyadi, Slamet; Sahir, Endang
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Carcinoma mammae is a cancer of thoracal region that most commonly found and suffered by women in Indonesia. Cancer patients may experience morbidity and psychiatric disorder. With rehabilitation, physical and psychological disorders which were caused by cancer could be reduced. This study aims to determine effects of medical rehabilitation towards stress level of post-surgical mammary carcinoma patients. Methods: This research is observational analytic study with cross-sectional approach. Subjects were patients who came to the clinic of Oncology and Medical Rehabilitation Installation of National Cancer Centre Dharmais. Research subjects were taken by purposive sampling technique. The research data were obtained through interviews using questionnaires. The collected data were statistically analyzed with Chi Square test using SPSS 17 software for Windows program. Results: From the research results, there is total 60 patients. Medium-category stress patients were 53 people, 25 people (47.2%) had never undergone medical rehabilitation, and 28 people (52.8%) had undergone medical rehabilitation. Severe-category stress patients were 7 people, 5 people (71.4%) had never undergone medical rehabilitation and 2 people (28.6%) had undergone medical rehabilitation. The results of calculations acquired a significance level of X²count is 0.228 > significance level of p = 0.05. Conclusions: Based on the result of statistical analysis, it can be concluded that there is no significant effects of medical rehabilitation towards stress level of post-surgical mammary carcinoma patients. Keywords: Carcinoma Mammae – Medical Rehabilitation – Stress Level
Pengaruh Usia terhadap Cervical Intraepithelial Neoplasia (CIN) pada Wanita dengan Infeksi Saluran Reproduksi Berbasis Pemeriksaan Papsmear Anggraini, Dewi Okta; Dirgahayu, Paramasari; Wasita, Brian
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Cervical Intraepithelial Neoplasia (CIN) is a dysplasia of cervical squamous cells posibbly turn into cervical cancer if not treated immediately. The established cause of CIN is Human Papillomavirus (HPV). Several studies showed correlation between Reproductive Tract Infection (RTI) with CIN. But, it is still controversial. Age is one of predicted factor which can influence CIN. Through some mechanisms, age can change the cervical cells. Methods: This study was cross-sectional approach. Samples were taken from medical record, papsmear’s form result and papsmear preparation in the Pathology Anatomy Laboratory, Faculty of Medicine, Sebelas Maret University from 2009-2012. Total of 410 samples were divided into two groups: control and case group. Control group contain sample without RTI while case group contain sample with RTI. Each group consisted of 205 women who subsequently divided into two subgroup, aged <40 years and ≥ 40 years. In this study, HPV infection is uncontrolled. Data were taken including name, age, clinical symptoms, ISR and CIN. These data are analyzed using Fisher test from SPSS version 19 for windows. Results: Total CIN were found: 5 samples (<40 years) and 3 samples (≥40 years) from positive RTI; 20 samples (<40 years) and 53 samples (≥40 years) from negative RTI. Fisher test results showed that age has correlation with CIN (p=0,001) and there is a significant difference risk between the age distribution with CIN [RD= -12.3%, 95%CI=(-19.8)-(-4798)]. In the negative RTI, there is a significant risk sample aged <40 years and aged ≥40 years to get CIN [RD= -21.28%, 95% CI= (-33.91)- (-8.655)]. RTI does not have correlation with CIN (p = 0.06) Conclusion: Without HPV controlled, age distribution (<40 years and ≥40 years) has an influence to the occurence of CIN and there is no correlation between RTI with CIN. Key words: Age, Cervical Intraepithelial Neoplasia (CIN), Reproduction Tract Infection (RTI)

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