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Paramasari Dirgahayu
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Faktor sosio ekonomi demografi terhadap kejadian infeksi kecacingan pada anak Sekolah Dasar Mahmudah, Umi; Dirgahayu, Paramasari; Wasita, Brian
Ilmu Gizi Indonesia Vol 1, No 1 (2017): Agustus
Publisher : Program Studi S-1 Ilmu Gizi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (310.538 KB)

Abstract

Latar belakang: Infeksi kecacingan merupakan masalah kesehatan masyarakat di negara-negara berkembang seperti Indonesia. Anak sekolah dasar merupakan golongan yang paling berisiko terhadap kejadian infeksi kecacingan. Infeksi ini dipengaruhi oleh beberapa faktor yaitu kondisi sanitasi lingkungan, perilaku personal hygiene,  serta kondisi  sosio  ekonomi demograf daerah sekitar. Kondisi sosio demograf yang berbeda di setiap wilayah mengakibatkan terjadinya infeksi kecacingan yang berbeda–beda. Tujuan: Untuk mengetahui hubungan faktor sosio ekonomi demograf  terhadap  kejadian  infeksi  kecacingan  pada  anak  sekolah  dasar. Metode: Penelitian ini merupakan penelitian observasional dengan rancangan cross sectional, pada populasi anak sekolah dasar kelas 1 sampai kelas 5 dengan jumlah 92 siswa, sedangkan besar sampel penelitian berjumlah 74 siswa di SD Barengan Kecamatan Teras Kabupaten Boyolali dengan teknik pengambilan sampel secara purposive. Data kecacingan pada anak diperoleh dengan pengambilan sampel feses dan diperiksa menggunakan metode  formol ether concentration di Laboratorium Parasitologi  Fakultas  Kedokteran  Universitas  Sebelas Maret.  Data  sosio  ekonomi  demograf diperoleh dengan kuisioner dengan metode wawancara. Analisis data diolah menggunakan chi square. Hasil: Prevalensi kejadian infeksi kecacingan pada anak sekolah dasar di SD Barengan Kecamatan Teras Kabupaten Boyolali adalah 40,21%. Pendidikan ayah (p=0,159) dan pendidikan ibu (p=0,352) tidak berhubungan dengan kejadian infeksi kecacingan. Penghasilan ayah (p=0,330) dan penghasilan ibu (p=1,152) tidak berhubungan dengan kejadian infeksi kecacingan. Kesimpulan:  Pendidikan ayah, pendidikan ibu, penghasilan ayah dan penghasilan ibu tidak berhubungan dengan kejadian infeksi kecacingan.Kata kunci: Sosio; ekonomi; demograf; infeksi kecacingan
PENGARUH PEMBERIAN JUS BUAH NAGA MERAH (Hylocereus polyrhizus) TERHADAP KADAR KOLESTEROL TOTAL TIKUS PUTIH (Rattus norvegicus) JANTAN MODEL HIPERKOLESTEROLEMIA Suryani, Irma; Dirgahayu, Paramasari; Wasita, Brian
Jurnal Gizi dan Kesehatan Vol 1, No 2 (2014)
Publisher : Program Studi Ilmu Gizi Pascasarjana Universitas Sebelas Maret

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Abstract

Abstract Background : Hyperlipidemia is a major cause of cardiovascular disease because it can lead to narrow of the arteries. Prevalence of diseases caused by hyperlipidemia is still quite high in many countries. Some therapeutic agents of modern medicine has been available, but most of these drug give side effects and the cost is quite high. The content of the red dragon fruit has been studied, which consists of fiber and antioxidants.This study was conducted to determine the effectiveness of antihiperlipidemia red dragon fruit juice compared with atorvastatin.Methods : Experimental with pre and post group randomized controlled design. The 36 samples were divided into six groups randomly: negative control group, positive control group (induction high fat diet for 14 days), group 1(induction high fat diet for 14 days and atorvastatin 10 days), 2, 3 and 4 (induction high fat diet for 14 days and red dragon fruit juice with a variety of doses for 10 days). The levels of lipid profiles of samples were measured before and after the intervention is given. Data were analyzed with SPSS 22.0 for windows. Result : After 14 days of margarine induction, group KP, P1, P2, P3, and P4 showed significant increase (p <0,05) on the average of total cholesterol, as well as in P1 with 0,18 mg of atorvastatin. Conclusion Red dragon fruit juice has the potential antihiperlipidemia comparable to atorvastatin Key words: Red Dragon Fruit, Lipid Profile, Atorvastatin
Red dragon fruit juice in reducing ros levels and insulin resistance In rats with type 2 diabetes mellitus model Putri, Mahendri Deayu; Wiboworini, Budiyanti; Dirgahayu, Paramasari
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 10, No 1 (2021): December
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.10.1.6-14

Abstract

Background: The peel of red dragon fruit (Hylocereus polyrhizus) had been proven to have a total polyphenol content and total flavonoids 2 to 3 times more than its flesh. These components could reduce oxidative stress and maintain the function of pancreatic beta cells, which could affect blood sugar levels.Objectives: This study aimed to test the red dragon fruit juice using peel and flesh to reduce oxidative stress and insulin resistance in T2DM model rats.Materials and Methods: This study was a true experimental study with a randomized controlled trial, with a Matching Pretest Post-test Control Group Design. We used 21 white male rats (Rattus norvegicus) Wistar strain which was divided into three groups: (P1) negative control group (induced Streptozotocin + Nicotinamide induction), (P2) positive control group (given Streptozotocin + Nicotinamide and given Metformin HCl induction 0,9 mg/kg BW, and (P3) Red Dragon fruit group (induced Streptozotocin + Nicotinamide and given Red Dragon Fruit juice 3.6 ml / 200 g BW / day given for 14 days. The data were analyzed using a one-way ANOVA test, paired t-test, and Post Hoc.Results: After 14 days of intervention, the average HOMA-IR levels were as follows: negative control group (Mean=8.32; SD=0.26), positive group (Mean 4.89; SD=0.29), and the Red Dragon Fruit intervention group (Mean=4.65; SD=0.30). The average MDA levels were as follows: control group (Mean = 9.08; SD = 0.68), positive group (Mean=3.34;SD=0.22), and the red dragon fruit intervention group (Mean = 3.05; SD = 0.47). Both the Metformin group and the Red Dragon Fruit group had low HOMA-IR and MDA levels compared to the negative control group.Conclusions: When administered alone, red dragon fruit and metformin effectively reduced HOMA-IR and MDA levels in rats with type 2 DM. Red dragon fruit can be used as an alternative to metformin because of its effectiveness in reducing plasma HOMA-IR and MDA.
Faktor sosio ekonomi demografi terhadap kejadian infeksi kecacingan pada anak Sekolah Dasar Umi Mahmudah; Paramasari Dirgahayu; Brian Wasita
Ilmu Gizi Indonesia Vol 1, No 1 (2017): Agustus
Publisher : Universitas Respati Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (310.538 KB) | DOI: 10.35842/ilgi.v1i1.14

Abstract

Latar belakang: Infeksi kecacingan merupakan masalah kesehatan masyarakat di negara-negara berkembang seperti Indonesia. Anak sekolah dasar merupakan golongan yang paling berisiko terhadap kejadian infeksi kecacingan. Infeksi ini dipengaruhi oleh beberapa faktor yaitu kondisi sanitasi lingkungan, perilaku personal hygiene,  serta kondisi  sosio  ekonomi demograf daerah sekitar. Kondisi sosio demograf yang berbeda di setiap wilayah mengakibatkan terjadinya infeksi kecacingan yang berbeda–beda. Tujuan: Untuk mengetahui hubungan faktor sosio ekonomi demograf  terhadap  kejadian  infeksi  kecacingan  pada  anak  sekolah  dasar. Metode: Penelitian ini merupakan penelitian observasional dengan rancangan cross sectional, pada populasi anak sekolah dasar kelas 1 sampai kelas 5 dengan jumlah 92 siswa, sedangkan besar sampel penelitian berjumlah 74 siswa di SD Barengan Kecamatan Teras Kabupaten Boyolali dengan teknik pengambilan sampel secara purposive. Data kecacingan pada anak diperoleh dengan pengambilan sampel feses dan diperiksa menggunakan metode  formol ether concentration di Laboratorium Parasitologi  Fakultas  Kedokteran  Universitas  Sebelas Maret.  Data  sosio  ekonomi  demograf diperoleh dengan kuisioner dengan metode wawancara. Analisis data diolah menggunakan chi square. Hasil: Prevalensi kejadian infeksi kecacingan pada anak sekolah dasar di SD Barengan Kecamatan Teras Kabupaten Boyolali adalah 40,21%. Pendidikan ayah (p=0,159) dan pendidikan ibu (p=0,352) tidak berhubungan dengan kejadian infeksi kecacingan. Penghasilan ayah (p=0,330) dan penghasilan ibu (p=1,152) tidak berhubungan dengan kejadian infeksi kecacingan. Kesimpulan:  Pendidikan ayah, pendidikan ibu, penghasilan ayah dan penghasilan ibu tidak berhubungan dengan kejadian infeksi kecacingan. 
Pendidikan Kesehatan tentang Personal Hygiene dan Pemeriksaan Kecacingan pada Anak Berkebutuhan Khusus di SLB Anugerah, Colomadu, Karanganyar Betty Saptiwi; Risya Cilmiaty, AR; Widia Susanti; Paramasari Dirgahayu; Adi Prayitno; Sutartinah; Pradipto Subiyantoro
Abdimas Universal Vol. 3 No. 1 (2021): April
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Balikpapan (LPPM UNIBA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36277/abdimasuniversal.v3i1.86

Abstract

Anak Berkebutuhan Khusus (ABK) di SLB Anugerah, Colomadu, Karanganyar Jawa Tengah memiliki personal hygiene yang kurang berdasarkan survey yang dilakukan pada 21 ABK di SLB Anugerah, Colomadu. Dari hasil wawancara dengan guru, belum pernah ada pendidikan kesehatan tentang personal hygiene dan belum pernah ada pemeriksaan kecacingan pada ABK di SLB Anugerah, Colomadu, Karanganyar. Oleh karena itu perlu upaya memperbaikinya. Tujuan dari kegiatan ini adalah melaksanakan salah satu komponen Tri Dharma Perguruan Tinggi yaitu pengabdian kepada masyarakat. Selain itu pengabdian ini juga bermanfaat untuk mencegah gangguan kesehatan umum siswa ABK di SLB Anugerah, Colomadu, Kabupaten Karanganyar. Metode pengabdian yaitu dengan pemeriksaan kesehatan mata, telinga, hidung, kulit, pengambilan sampel anal swab, memberi pemahaman dan contoh kepada tiap siswa setelah diperiksa tentang pemeliharaan kebersihan diri yang benar. Sasaran yang diperiksa berjumlah 21 orang. Hasil pengabdian menunjukkan 21 siswa memiliki hasil negatif pada pemeriksaan kecacingan, 13 siswa (61,9%) memiliki serumen di telinga, 2 siswa (9,5%) tampak adanya hiperemis dan oedem pada hidung. Sementara untuk pemeriksaan lain sudah dalam kondisi baik. Hasil yang negatif pada pemeriksaan kecacingan, masih perlu dilanjutkan dengan pemeriksan sampel feses untuk mendeteksi jenis cacing lain yang tidak bisa dideteksi dengan anal swab dan juga ditambah dengan pengambilan sampel kuku karena pada sampel kuku bisa ditemukan adanya telur cacing.
Recent update on cerebral sparganosis: A bibliometric analysis and scientific mapping Dirgahayu, Paramasari; Ilyas, Muhana F.; Rahma, Annisa A.; Hanifa, Shafira N.; Wijayanto, Matthew A.; Triniputri, Winastari Y.; Lukas, Graciella A.; Wiyono, Nanang; Sari, Yulia; Mashuri, Yusuf A.
Narra J Vol. 4 No. 2 (2024): August 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i2.982

Abstract

Human sparganosis, a parasitic infection prevalent in Asia, can progress to cerebral sparganosis, a severe condition with significant neurological symptoms. Diagnosis and treatment are challenging due to its clinical similarity to other infections, highlighting the need for improved detection and management strategies. The aim of this study was to observe research trends, key contributors, gaps in the existing knowledge, diagnosis challenges, effective treatment options, and prevention strategies, providing recommendations for future research directions and clinical practice improvements on cerebral sparganosis. A bibliometric analysis was conducted by extracting 139 documents from the Scopus database in June 2024. The retrieved data were analyzed using the R package's Bibliometrix (Biblioshiny) and VOSviewer. Spanning 97 different sources, the research exhibited an annual growth rate of 2.5%. Annual scientific production revealed fluctuating research activity with peaks in 2010 and 2011 and notable citation peaks in 1996 and 2005, indicating pivotal studies that significantly influenced subsequent research. Early studies focused on diagnosis and specific parasites, while recent studies (2010–2024) have increasingly addressed clinical outcomes, treatment strategies, and advanced diagnostic techniques. Trends revealed a shift towards clinical and diagnostic advancements, with recent emphasis on diagnostic imaging, immunoassays, and the relationship between cerebral sparganosis and brain tumors. In conclusion, the studies on cerebral sparganosis underscore the potential for enhancing clinical practice by improving diagnostic accuracy, informing treatment decisions, and implementing targeted screening efforts based on epidemiology and risk factors. Recommendation to further study needs to notify the cerebral sparganosis in high-risk countries with similar socioeconomic and cultural characteristics to endemic regions, including Indonesia.
Scoping Review: Potential of Bekul Fruit (Ziziphus jujube Mill.) as an Antidiabetic Agent in Patients with Type 2 Diabetes Mellitus Windayani, Komang; Dirgahayu, Paramasari; Febrinasari, Ratih Puspita
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4301

Abstract

Diabetes mellitus is a metabolic disorder characterized by high blood glucose (hyperglycemia) caused by damage or abnormalities in insulin production. Pharmacological therapy used as a treatment for diabetes mellitus in some patients has adverse side effects on the body, thus encouraging exploration to use natural ingredients as an alternative therapeutic source in reducing blood glucose. Therefore, a thorough review is needed to summarize scientific data and investigate the potential use of natural ingredients bekul fruit (Ziziphus jujube Mill.) in its role as an antidiabetic agent. This study used a scoping review with 4 databases: Pubmed, ScienceDirect, DOAJ and Google Scholar. The results of the scoping review of 5 scientific articles found that bekul fruit (Ziziphus jujube Mill.) is proven to have bioactive content that is rich in antioxidants such as phenolic/polyphenolic compounds (ferulic acid, caffeic acid, chlorogenic acid), flavonoids (quercetin, rutin, catechin), phytosterols, and inulin which have the potential as antidiabetic agents with different mechanisms of action in reducing blood glucose levels. Conclusion: bekul fruit (Ziziphus jujube Mill.) has the potential to be an alternative nutraceutical diet therapy in patients with diabetes mellitus.
Beetroot Powder (Beta vulgaris L.) Decrease Oxidative Stress by Reducing of Malondialdehyde (MDA) Levels in Hyperuricemia Wulandari, Anggraini; Dirgahayu, Paramasari; Wiboworini, Budiyanti
Journal of International Conference Proceedings Vol 4, No 1 (2021): Proceedings of the 9th International Conference of Project Management (ICPM) Mal
Publisher : AIBPM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32535/jicp.v4i1.1156

Abstract

Introduction: Hyperuricemia is a metabolic disease associated with lifestyle habits, age, sex, and inherited factors. High uric acid levels in a hyperuricemia state cause oxidative stress that can lead to increased malondialdehyde (MDA) levels. Beetroot powder has the potential as a functional food rich in antioxidants that can reduce MDA levels. This study aims to determine the beetroot powder effect on MDA level reduction in hyperuricemia rat models. Methods: This research was an experimental study with fifteen hyperuricemia rats were divided into three groups by randomized pre-post control group design. They were divided into three groups: P1 were healthy rats + standard feed (comfeed), P2 were hyperuricemia rat models + standard feed (comfeed) and P3 were hyperuricemia rat models + beetroot powder 3,12 g/kg/bw for 14 days. The MDA level examinations were conducted on day 0 and day 14. Results: After 14 days of treatment, the P3 group has a significant decrease in MDA levels compared to day 0 (p = 0.042). Groups P1 and P2 have a significant increase in MDA levels (p = 0.043). MDA levels between groups were significantly different (p = 0.002) on day 14. Conclusion: Giving beetroot powder for 14 days with dose 3,12 g/kg/bw for 14 days significantly reduced MDA levels in hyperuricemia.
Effect of walking and bone joint exercise on enhancing bone remodeling in menopausal women: A randomized controlled trial Pasa, Chusairil; Pamungkasari, Eti P.; Doewes, Muchsin; Purwanto, Bambang; Hartono, Hartono; Cilmiaty, Risya; Dirgahayu, Paramasari
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.1321

Abstract

Osteoporosis increases fracture risk and reduces quality of life in menopausal women. Although physical activity, such as walking and bone joint exercise, is known to help maintain bone health, its effectiveness needs further examination. The aim of this study was to analyze the effects of physical activity, in particular walking and bone joint exercise, on enhancing bone remodeling in menopausal women. A randomized controlled trial was conducted among menopausal women and allocated into three groups: walking, bone joint exercise, and control groups. The intervention was provided for eight weeks, with the outcomes measured before and after the intervention. The study assessed five bone remodeling biomarkers: estrogen, parathyroid hormone (PTH), receptor activator of nuclear factor kappa-β ligand (RANKL), tumor necrosis factor-alpha (TNF-α), and bone mineral density (BMD). The paired sample student t-test and ANOVA were used to assess the effects of the interventions. The results indicated that, compared to pre-intervention, both walking and bone joint exercise significantly increased the estrogen (p=0.026 and p=0.023, respectively), decreased RANKL (p=0.019 and p=0.002, respectively), decreased PTH levels (p=0.022 and p=0.048, respectively) and increased the BMD scores (p=0.001 and p<0.001, respectively). In the control group, none of the remodeling biomarkers significantly changed except the mean level of TNF-α, which was increased significantly (p=0.001). This study highlights that structured exercise, such as walking and bone joint exercise, can significantly enhance bone remodeling markers in menopausal women. Therefore, implementing such physical activities into management may provide benefits to menopausal women.
OLAHRAGA DAN KONSUMSI BUAH SEBAGAI NUTRISI MEDIS PADA PENYAKIT TIDAK MENULAR (PTM): Exercise and Fruit Consumption as Medical Nutrition for Non Communicable Diseases (NCDs) Wijayanti, Lilik; Haryati, Sri; Dirgahayu, Paramasari; Suparyanti, Endang Listyaningsih; Negara, Khesara Sastrin Prasita; Riyadi, Slamet; Supriyana, Dwi Surya; Ma'rufah, Siti; Setyawan, Sigit
JAMAS : Jurnal Abdi Masyarakat Vol. 3 No. 1 (2025)
Publisher : Forind Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62085/jms.v3i1.174

Abstract

Penyakit Tidak Menular (PTM) atau biasa juga disebut sebagai penyakit degeneratif  adalah merupakan jenis penyakit yang tidak bisa ditularkan oleh penderita ke orang lain, jenis penyakit ini berkembang secara perlahan dan terjadi dalam waktu yang panjang. Beberapa penyakit yang termasuk PTM adalah diabetes mellitus (DM) dan hipertensi. Kegiatan  ini  untuk menambah  pengetahuan tentang  olah raga dan  konsumsi buah sebagai nutrisi medis pada pasien PTM. Pengabdian kepada masyarakat (PkM) dilakukan terhadap 36 orang pasien yaitu  15 orang pasien DM dan 21 orang penderita hipertensi di kelompok prolanis K – Nisa. Pasien yang datang dilakukan pengukuran tekanan darah, penghitungan nadi latihan, penyuluhan tentang DM, hipertensi dan penghitungan nadi latihan, olah raga dan pengisian kuosioner sambil dilakukan focus group discussion. Hasil pengisian kuosiner sudah beberapa pengetahuan yang memberikan hasil yang baik dan beberapa yang masih memerlukan peningkatan. Pengetahuan yang sudah baik yaitu pengetahuan tentang olah raga, nadi latihan, komplikasi PTM, definisi tekanan darah tinggi, manfaat olah raga dan durasi waktu olah raga dan jumlah konsumsi buah. Pengetahuan yang masih perlu ditingkatkan adalah gejala awal penyakit DM dan hasil pemeriksaan gula darah pada pasien DM. Dari hasil kegiatan ini diperlukan adanya sosialisasi yang terus menerus kepada masyarakat tentang gejala awal penyakit DM dan perlunya pemeriksaan gula darah. Pengetahuan pasien PTM sudah baik tentang olah raga dan konsumsi buah sebagai nutrisi medis.
Co-Authors Adi Magna Patriadi Nuhriawangsa Adi Prayitno Adi Ratriyanto Amandha Boy Timor Randita Ambar Mudigdo Anif Nur Artanti, Anif Nur Annang Giri Moelyo Annang Giri Moelyo Antonius Christanto ARI SUSILOWATI Aryanda Widya Tazkagani Salsabila Aulia Nadhiasari Bambang Pujiasmanto Bambang Purwanto Bambang Sukilarso Sakiman Betty Saptiwi Brian Wasita Brian Wasita Budiyanti Wiboworini Christanto, Antonius Dani Redhono Haryoputro Dewi Okta Anggraini Dhani Redhono, Dhani Dono Indarto Dwi Surya Supriyana Edi Purwanto Endang Listyaningsih S Endang Listyaningsih Suparyanti Endang Yuniastuti Eti Poncorini Pamungkasari Fadila, F Hanifa, Shafira N. Hartono Hartono Ida Nurwati Ida Rumia Manurung Ilyas, Muhana F. Irma Suryani Lilik Wijayanti Lukas, Graciella A. Ma'rufah, Siti Made Setiamika Mashuri, Yusuf Ari Ma’rufah, Siti Muchsin Doewes Nabila Adib Sungkar Nabila Adib Sungkar Nanang Wiyono Nandariyah, Nandariyah Negara, Khesara Sastrin Prasita Pamungkasari, Eti P. pasa, chusairil Pradipto Subiyantoro Putri, Mahendri Deayu Rahma, Annisa A. Ratih Dewi Yudhani Ratih Puspita Febrinasari Risya Cilmiaty Risya Cilmiaty, AR Risya Cilmiaty, Risya Sahara, Nita Samanhudi Samanhudi Setiamika, Made Sigit PRASTOWO Slamet Riyadi Sopianti, Densi Selpia Sri Hartati Sri Haryati Sri Mulyani Sulandjari Sulandjari, Sulandjari Sumandjar, Tatar Sundari, Isti Surya Dewi Primawati Sutartinah Tamaulina Br Sembiring Triniputri, Winastari Y. Umi Mahmudah Venty Suryanti Widia Susanti Wijayanto, Matthew A. Windayani, Komang Wulandari, Anggraini Yanita Listianasari Yulia Sari Yunus, Ahmad