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INDONESIA
Jurnal Kesehatan Andalas
Published by Universitas Andalas
ISSN : 23017406     EISSN : 26151138     DOI : -
Core Subject : Health,
Health Professions
Jurnal Kesehatan Andalas merupakan Jurnal yang diterbitkan oleh Fakultas Kedokteran Universitas Andalas.
Arjuna Subject : -
Articles 7 Documents
 1 
Search results for , issue "Vol. 13 No. 1 (2024): March 2024" : 7 Documents clear
Hubungan Kadar Enzim Transaminase Pasien COVID-19 dengan Derajat Keparahan Penyakit di RSUP Dr. M. Djamil Padang Rahmadina, Rahmadina; Herman, Deddy; Efrida, Efrida; Almurdi, Almurdi; Russilawati, Russilawati; Elvira, Dwitya
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2205

Abstract

Liver injury can be caused by coronavirus disease 2019 (COVID-19), characterized by increased levels of transaminase enzymes (aspartate aminotransferase/AST and alanine aminotransferase/ALT). Objective: To determined the correlation between transaminase enzyme levels and the severity of COVID-19 in Dr. M. Djamil Central Public Hospital, Padang. Methods: This was an observational analytic study with a cross-sectional design. Data were obtained randomly from medical records of confirmed COVID-19 patients hospitalized in Dr. M. Djamil Hospital from June to August 2021, with moderate, severe, and critical severity based on Indonesian Ministry of Health criteria. Data were analyzed using the Chi-square test to examine the distribution and correlation between variables and a simple logistic regression test to assess the level of risk between variables. Results: 57,80% had abnormal AST, and 44,95% had abnormal ALT. The median AST was highest in the critical group, while the median ALT was highest in the severe group. The distribution of sex and age group were significantly different based on AST and ALT levels, and the distribution of patients with coronary heart disease was significantly different based on ALT levels. Transaminase enzyme levels had a significant correlation with the severity of COVID-19 (p-value = 0,00). Patients with critical degrees had the highest risk for abnormal AST and severe degrees had the highest risk for abnormal ALT. Conclusion: Transaminase enzymes have a significant correlation with the severity of COVID-19.Keywords:  COVID-19, liver injury, transaminases, disease severity
Efek Loading Statin Intensitas Tinggi Sebelum Intervensi Koroner Perkutan pada Pasien Sindrom Koroner Akut: Systematic Review Suwari, Cokorda Istri Padmi; Claudia, Mutiara
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2244

Abstract

Percutaneous Coronary Intervention (PCI) is one of the essential methods for Acute Coronary Syndrome (ACS) treatment, but this procedure has serious complications. Early loading dose statin has a favorable prognostic impact on patients undergoing PCI. However, this effect is still unclear.Objective: To evaluated the effect of loading high-intensity statin on Major Adverse Cardiac Events (MACE) before PCI in patients with ACS. Methods: Randomized controlled trials were conducted using databases from  CENTRAL, PubMed, Science Direct, and British Medical Journal. Then, titles, abstracts, and full texts were screened using the inclusion criteria to filter out irrelevant studies. Quality assessments were undertaken using the Jadad scale, and the results were narratively synthesized and presented in tables. Results: Seven studies were included in this systematic review after screening 1037 records. Four studies demonstrated a statistically significant reduction in MACE in the groups that received loading dose atorvastatin or rosuvastatin before PCI, compared with the comparator groups (p < 0.05). Conclusion: Loading high-intensity statin before PCI seems to be highly effective in reducing MACE in patients with ACS.Keywords:  acute coronary syndrome, major adverse cardiac events, percutaneous coronary intervention 
Gambaran Radiografi Toraks Sebagai Prediktor Outcome Pasien COVID-19 Safarini, Bekti; Sutikno, Dria Anggraeny; Intisari, Dewi
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2278

Abstract

COVID-19 (coronavirus disease 2019) is a pulmonary infection disease caused by SARS-CoV-2. Chest radiographic examination of COVID-19 cases performed to make a diagnosis and monitor therapy. Objective: To    evaluated the results of chest radiography examination in COVID-19 cases as a predictor of patient outcome after treatment at the Sultan Agung Islamic Hospital in Semarang. Methods: This research was an observational analytic study with a retrospective design using medical record data from January until December 2021. The results of chest radiographs were analyzed using the Brixia Score system with a maximum score of 18. Outcomes of COVID-19 patients were described as recovered patients or died. Data analysis uses the ROC curve to determine the cut-off point. Results: This study showed that out of 47 patients (43±14 years old), 39 patients (81%) recovered and nine patients died (19%). The levels of leukocytes, D-dimer, Neutrophil-lymphocyte ratio (NLR), and Brixia scores were significantly higher in dead patients (p<0.05). Sensitivity and specificity values predictor of leukocyte count (83%, 61%), D-dimer (83%, 84%), NLR (83%, 82%), and Brixia score (83%, 79%), respectively. Conclusion: Increased levels of leukocytes, D-dimer, NLR, and Brixia Score can be used as a predictor of patient mortality after hospitalization.Keywords: Brixia score, COVID-19, thoracic radiograph
Prevalence of Commorbid Lung Tuberculosis Diabetes Mellitus in Sultan Syarif Mohamad Alkadrie Pontianak Hospital in 2019 Ardhi, Terence; Fitriangga, Agus; Putri, Eka Ardiani
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2284

Abstract

Pulmonary tuberculosis (TB) can be made worse by a history of Diabetes Mellitus (DM), which can increase the risk of failure treatment, relapse, and longer duration of treatment.  Objective: To find out the prevalence of Pulmonary TB comorbid DM at Sultan Syarif Mohamad Alkadrie General Hospital Pontianak. Methods: This research was a descriptive observational study with a cross-sectional design. The population in this study were all patients diagnosed with pulmonary tuberculosis at the Sultan Syarif Mohamad Alkadrie Hospital Pontianak from 1 January to December 31st, 2019. Data collection was carried out by taking secondary data on patients diagnosed with pulmonary TB with a history of DM in outpatient and inpatient installations at Sultan Syarif Mohamad Alkadrie General Hospital Pontianak.Results: There were 1311 pulmonary TB patients in Sultan Syarif Mohamad Alkadrie General Hospital Pontianak in 2019; pulmonary TB patients with a history of DM as many as 98 patients obtained from 73 outpatient installations and inpatients hospitalized as many as 25 patients. The results showed that the prevalence of pulmonary TB comorbid DM was 7.47%. Conclusion: The prevalence of pulmonary TB comorbid DM in RSUD Sultan Syarif Mohamad Alkadrie Pontianak is relatively low.Keywords:  ages, diabetes  mellitus, pulmonary TB
Perbandingan Persepsi Pasien Tuberkulosis Paru terhadap Kualitas Pelayanan Pengobatan Tuberkulosis di Puskesmas Kampung Bali dan Puskesmas Perum I di Kota Pontianak Amiralevi, Siti Haura; Fitriangga, Agus; Ilmiawan, Muhammad In’am
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2316

Abstract

Increasing access to quality Tuberculosis (TB) services and patient-centered care is one strategy to eliminate TB. Objective: To determined the comparison of the perception of pulmonary tuberculosis patients at the Kampung Bali Health Center and the Perum I Health Center in Pontianak City. Methods: Cross-sectional analytical observational design with total sampling method on 34 patients with details of 17 patients at the Puskesmas Kampung Bali and 17 at the Puskesmas Perum I. This research used the QUOTE-TB Light questionnaire and the Mann- Whitney comparison test as the statistical test. Results: There are no differences in the dimensions of the availability of TB services (p=0.520), communication and information (p=0.420), interaction and counseling (p=0.722), infrastructure (p = 0.608), affordability (p=1,000), and stigma (p=0,966) and there is a significant difference in the dimensions of professional competence (p=0.007). Conclusion: There is a difference in professionalcompetences. It is necessary to evaluate the competence and performances of health workers at Puskesmas Kampung Bali and Puskesmas Perum I.Keywords: Quality of TBC treatment services, patient’s perspective, QUOTE-TB Light, Tuberculosis  
Hubungan Antara Volume Prostat dan IPSS Score pada Pasien BPH di Rumah Sakit Siti Khodijah Muhammadiyah Cabang Sepanjang Waskita, Shakina Reza; Putra, Muslim Andala; Mochtar, Nur Mujadiddah; Himawan, Budi
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2317

Abstract

Benign Prostatic Hyperplasia (BPH) is the growth of non-malignant cells or hyperplasia of prostate tissue, which causes Lower Urinary Tract Symptoms (LUTS) in men. One guide to direct and determine the symptoms of obstruction due to prostate enlargement is the International Prostate Symptom Score (IPSS). Objective: To determined the relationship between prostate volume and IPSS score in BPH patients at Siti Khodijah Muhammadiyah Cabang Sepanjang Hospital. Methods: This was an analytic observational study using a prospective cohort method. The sample selection used consecutive sampling techniques in accordance with predetermined inclusion and exclusion criteria for collecting data using primary and secondary data, abdominal ultrasound data, and the IPSS questionnaire. The number of samples used was 30 patients from November 2022 to April 2023. Results: The prostate volume in grade II was 46.7%, while for grade I and grade III were 33.3% and 20%, respectively. For the results of the IPSS, the moderate category was 76.7%, with mild and severe IPSS scores at 10% and 13.3%, respectively. The Spearman test results showed that the p-value was 0.006 <0.05, the value of r = 0.486, and the correlation coefficient was positive, meaning there was a unidirectional relationship between prostate volume and the IPSS score. Conclusion: There is a reasonably strong relationship between prostate volume and IPSS score in BPH patients at Siti Khodijah Muhammadiyah Cabang Sepanjang Hospital.Keywords:  BPH, prostate volume, IPSS
Potensi Eugenol Fraksi Etil Asetat Bunga Cengkeh terhadap Proliferasi Kanker Serviks (HeLa Cell Line) Pratama, Fajri Rahendra; Sari, Annisa Permata; Susanti, Aprilia; Syakira, Hasya; Salsabila, Amilia; Arisanty, Dessy
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2326

Abstract

Cervix cancer, also known as cervical cancer, is a type of cancer that is caused mainly by oncogenic Human Papillomavirus (HPV), which attacks the cervix. One of the plants that can be used in medicine is clove. Objective: To analyzed the effect of a fraction of ethyl acetate eugenol of clove flower for the proliferation and migration of HeLa cells. Methods: This was an in vitro experiment. Ethyl acetate fraction was tested in vitro with the MTT Assay method. A scratch Assay is done to determine the migratory power of cancer cells to Trypan Blue to see (dead cells/living cells). Data collection techniques were carried out using experimental observation techniques. The data obtained in the MTT test is the percentage of inhibited HeLa cells. Scratch Assay results were analyzed with ImageJ software and the Trypan Blue method using the TC10 tool. Results: The MTT Assay test obtained an IC50 value of 24.51 µg/ml, the average migration of treatment cells 303 and the average control group 715 cells. The number of proliferating treatments 6.14 x 105 and control 12.1 x 105. Conclusion: Based on its potential, clove flower can be a candidate for cervical cancer cell therapy (HeLa Cell Line) in the future.Keywords:  anti-cervical cancer, cervical cancer, cell proliferation, MTT assay, scratch assay 

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