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INDONESIA
Program Kreativitas Mahasiswa - Penelitian
Published by DITJEN DIKTI KEMDIKBUD RI
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Articles 39 Documents
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Search results for , issue " PKM-P 2014" : 39 Documents clear
PEMANFAATAN TEKNOLOGI DIMPLE PADA LAMBUNG KAPAL UNTUK MENGURANGI TAHANAN KAPAL Firmanullah, Dhani Mishbah; Firmansyah, M Wahyu; Santoso, Fandhika Putera
Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Research in fluid mechanics are developed to decrease the resistance of the ships by the flow on the surface of wet surace area. Fluid on the wet surface area will be create a friction. One of solution to decrease the force of friction is modification itself. The applications of marine, resistance of the ship will be effect to the require power to move the ship on the service velocity. Decrease of the total resistance will be decrease the require power of the engine that affect to the oil consumption of the ship. Dimples is the basines that can modification the fluid flow on the wet surface area of the ships. It can reduce the total resistance. The purpose of this research are to know the information about best horizontal distance between each dimple, to know the value the friction coefficient, and the total resistance between dimple installation and non dimple or normal hull construction. The method on this research is the simulation using Computational Fluid Dynamics (CFD). Dimple using 0,5 m for diameter, 0,15 m for the depth, and 1,5 m for the vertical distance. The principle dimension for the length between perpendicular is 117 m, breadth 20 m, height 9,2 m, and draught 6,9 m. The variables is the horizontal distance with the value 3, 4, 5 m, velocity 8, 10, 12, 14, 16, 18 knots. The results of this research are the best distance is 4 m and can reduce the total resistance 16,48 %.Keywords: Friction Force, Dimple, Computational Fluid Dynamics
POTENSI VAKSIN ATEROSKLEROSIS VIA INDUKSI PROTEIN LECTIN-LIKE OXIDIZED LDL RECEPTOR 1 (LOX-1) TERHADAP AKTIVASI NF-κB, EKSPRESI eNOS DAN KADAR CRP PADA TIKUS DENGAN DIET ATEROGENIK Albaar, Thoha Muhajir; Tamara, Fredo; A, Oktavia Rahayu; Putri, Ardina Pramesti; Nurkhairina, Angi; Yurina, Valentina
Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Atherosclerosis is a chronic inflammation condition as a response to the lipoproteins deposition in the artery wall.Oxidized low density lipoprotein (OxLDL) the major of atherosclerosis development. Lectin- like oxidized lo density lipoprotein 1 (LOX-1) is primary  receptor for OxLDL in endothelial cells. Recent studies have shown that LOX-1 might be potential for the atherosclerosis drugs development. This study was designed to investigate the response of LOX-1 vaccination with alum as adjuvant for atherogenesis to prevent increasing of NF-kB , CRP, and decrease of eNOS. This study was experimental laboratory with post test only control group design for 56 days using 28 male Wistar rats. Rats were divided into 7 groups which were negative control with normal diet AIN 93 M, positive control with atherogenic diet AIN 93 M, atherogenic diet AIN 93 M and LOX-1 protein treatment with dosage 1 ng + alum (P1), 10 ng + alum (P2), 100 ng + alum (P3), 1μg + alum (P4) and alum only (P5). On the 57th day, the rats were sacrificed and taken its serum spesimen to measure CRP level with enzyme immunoassay method and aorta tissues to measure NF-kB activation and expression eNOS with immunohistochemical method. Statistical analysis showed that the administration of LOX-1 protein in the treatment groups is significant to prevent NF-kB activation (p=0,00) and prevent decreased expression of eNOS (p=0,00), but not significant to prevent increased CRP level (p=0,83). The conclusion of this study is that the LOX-1 protein vaccination  have potency to prevent atherosclerosis with decreasing NF-kB activation and prevent decreasing eNOS expression. Keywords:  Atherosclerosis vaccine, LOX-1, NF-kB, eNOS, CRP
POTENSI BIJI LABU KUNING SEBAGAI AGEN FITOESTROGEN PADA WANITA POST MENSTRUAL Lestari, Beni; Hanif, Naisbitt Iman; Anggarany, Ariska Deffy; Ziyad, Thoriq; Walidah, Ziana; Murwanti, Retno
Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Osteoporosis and hypercholesterolemia are prevalent condition in menopausal women. The common therapy to prevent the estrogen degrading condition is Hormone Replacement Therapy (HRT). However, HRT possessed various risks. Curcubita pepo L. seed (pumpkin seed) contains lignan secoisolariciresinol and lariciresinol which exhibit estrogenic effect. The aim of this study is to determine the estrogenic effect of Ethanolic Extract of Pumpkin Seeds (EEPS) through in silico and in vivo study. In silico study were conducted by molecular docking of lignan which is secoisolariciresinol and lariciresinol with Estrogen Receptor (ERα and Erβ). In vivo study conducted by using ovariectomized Sprague dawley female rats as a model of postmenopausal women. Blood lipid profile, bone density, and uterine weight were assayed after thirty days. Molecular docking score of secoisolariciresinol and lariciresinol were similar to estradiol. In vivo study found that EEPS increase bone density and uterine weight percentage while also improve the blood profile. In conclusion, these result showed that EEPS is potential to be developed as an osteoporosis and hypercholesterolemia prevention agent. Keywords:  Lime peel, Limonene, Aromatic candles, Repellent
ANALISIS JERAMI PADI UNTUK PEMBUATAN MIKROMEMBRAN SEBAGAI PENDAUR AIR LIMBAH RUMAH TANGGA Febriyana, Nur Aini; Mirfada, Zakiyatul; Jamila, Nurul; Wijayanto, Ach. Afif; Pradana, Novan
Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

The increase of population in Indonesia led to increased domestic waste. In addition, agricultural waste in Indonesia is very potential, such as rice straw. Rice straw ash contains silica which reached 94.5% silica is the main content of the base material micromembrane to absorb pollutants. Membrane separation is a medium that is selectively permeable to withstand certain components and skip the other components. Experimental procedures in this study includes the synthesis of silica, the manufacture of the membrane, and the membrane analysis. The results showed that the pore size of the membrane meets the standards mikromembran size from 0.3 to 10 lm. Rice straw silica functional groups located at the wave number of 3503.45 cm-1. Silica clusters seen at the peak of 1097.42 cm-1, which showed a group siloksa Si-O-Si. Optimal mass of silica used for the manufacture of silica membrane is 5 grams. The silica membrane was tested lowering the pH value from 7.2 to 6.9 caused a lot of impurities are retained and bind to the membrane. Micromembrane also lower turbidity values with 92% rejection and filter bacteria from 66000 into a 5500 colony. Keywords:  straw, waste, membrane
EKSTRAKSI MINYAK ATSIRI DARI DAUN DAN BATANG CENGKEH DENGAN METODE HYDRO-DISTILLATION DAN STEAM-HYDRO DISTILLATION UNTUK MENINGKATKAN NILAI TANAMAN CENGKEH DAN MENENTUKAN PROSES EKSTRAKSI TERBAIK Santoso, Joko; Hutama, Fajar Mardhi; Lystyoarti, Fatina Anesya; Nilatari, Lidya Linda
Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

The largest component contained in clove oil is eugenol by 70-80%. The purpose of this research is to study the process of extracting cloves oil use steam-hydro distillation and steam distillation method by microwaves. In addition, studying the factors that influence the extracting process such as power of microwaves, treatment of materials (mesh size 8 and 4 mesh), and the mass of material to the yield and quality of clove oil produced. The operating conditions for these two methods is the mass of 50, 80, 140, and 170 grams, atmospheric pressure (1atm), and temperature of 110oC steam. From the research, can be concluded that the hydro steam distillation method is the best extraction process.Keywords:  clove oil, eugenol, steam hydro distillation
HUBUNGAN SENYAWA FLAVONOID DARI KULIT BATANG Erythrina Fusca L. DENGAN UJI AKTIVITASNYA SEBAGAI SUNSCREEN N., Fatmawati; N., Anggreini; Y., Firmansyah M.; W., Erdityo C.; E., Yunilawati
Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

The Objective of this research to isolate and identificate phenolic compounds from the stem bark of Erythrina fusca L. and determining sunscreen activity, yielded pterocarpan compound, sandwicensin. This compound isolated and purificated by various chromatographic techniques, such as liquid vacuum chromatography, flach column chromatography, and radial chromatography. Structure of sandwicensin was elucidated based on spectrophotometric method such as UV, IR, HR-ESIMS, 1H and 13C NMR also 2D NMR (HMQC and HMBC). Sunscreen activity of sandwicensin obtained by calculating % T eritema and % T pigmented from the UV Spectrophotometre showing a sunscreen activity.Keywords:  Flavonoid compound, Sanwisensin, Erythrina fusca L., Sunscreen
REPRESENTASI MAKSIM PKS DALAM TUTURAN INTERAKSI PEMBELAJARAN BI DI KELAS XI SMA 1 KEERA KABUPATEN WAJO Ayu, Sutra; Mirdawana, Mirdawana; DM, M. Nazar
Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Basic Konstruk PKS is outside language used as principles of rational communications, eventhough it affects the choice in language elements, regulation, and its speech interpretation. PKS is essentially a communication rules that are beyond language. Therefore, it can be delivered speech act communicatively, if the maxim of quantity, quality, relation, and how to be noticed by the participant said. Violations maxims said into four types, namely violate,  opt out, clash, and flout. Violete occurred because the participants said not being able to use the maxim is true. Type of writing in scientific papers are qualitative approach is used because this research has the characteristics of (a) has a natural background as a source of data directly by using the researcher as a key instrument, (b) is a description, (c) concerned with the process than the results, (d) using inductive data analysis, and (e) emphasizes meaningfulness. This research is expected to solve the problem of violations Cooperation Principle. Keywords:  interaction of teaching, maxim, violation
APLIKASI MOBAJI: MENINGKATKAN PERTUMBUHAN TANAMAN DAN PENGENDALIAN HAMA PENGGEREK BATANG PADI Aulia, Desi; Ariswanto, Joko; Setiyorini, Yekti Agus; Nisa’, Choirun; Siswanto, Joko
Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

One of the important pest in rice plants that triggers production declining of rice is rice yellow stem borer (Scircophaga incertulas) that can lead to crop yield failure. This pest attacks on the generative stage of rice plants and known as ‘beluk’. MoBaJi is the mixture of MOL (local microorganism), onion extract and neem seed extract which serves as a botanical pesticide and as growth acceselerator of rice plants. The experiment was conducted in the laboratory of plant protection and FP-UB’s greenhouse. The research was conducted from February to June 2014. Randomized block design (RBD) was used for this research. This research contained 6 treatments with 3 replications with different concentration in each replication, and the treatments were repeated 3 times. The observations carried out up to 90 DAT of MoBaJi with scoring method. The variables of observations included plant height, tiller number, leaf number and intensity of pest attact. The results showed that MoBaJi’s treatment provided the highest influence on the mean of plant height that reached 64.71 cm (control: 51.45 cm), increase the  tillers number (4 tillers compared to 2.8 tillers in control). The mean number of leaves in MoBaJi tratment were 26 strands (19 strands in control). The observation of pest attack intencity on the field showed that there were no visible pest attack in MoBaJi’s treatment. This results was confirmed by testing on a petridish of pests (early instars yellow rice stem borer larvae) and non-target insects (crickets). MoBaJi’s treatment was able to kill pests up to 90-100% within 4 hours without killing non-target insects, in contrast to chemical pesticides that killed both pests and non-target insects.Keywords:  Rice, rice yellow stem borer, MoBaJi
POTENSI EKSTRAK HEKSAN DAUN KAPUR (Harmsiopanax aculeatus, Harms) SEBAGAI OBAT ANTIMALARIA Salenussa, Jusuf; Wijaya, Jefry; Labetubun, Colincie Natalia; Belseran, Stenly Erwin
Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Kapur plant (Harmsiopanax aculeatus, Harms) is traditionally used by Mollucans to treat malaria disease. Squeezed of young leaves which is dropped on the eye of sufferer is the way of its treatment. This research is aimed to assay haem polymerization inhibition activity, cytotoxic activity toward vero cells and to analysis chemical secondary metabolit of compound content on hexane extract of the old kapur leaves. Dried powder of kapur leaves (1 kg) is extracted by maceration technique using hexane solvent obtained 24.34g (2.43%) of hexane extract. Those extract which assayed haem polymerization inhibition on activity by Bassilico et al. (1998) method and cytotoxic test toward vero cells using MTT assay. Probit analysis has showing us that hexane extract of ripe kapur leaves were inhibit haem polymerization actively with IC50 in the amount 59.473 µg/mL and were not toxic toward normal cells with IC50 in the amount 1270.746 µg/mL. Phytochemical analysis by spray and visible reagent shown of steroid compound. Keywords:  Harmsiopanax acuelatus Harms, haem polymerization inhibition activity, cytotoxic activity, vero cell, phytochemical
EKSTRASI DEDAK PADI SEBAGAI PENGAYAAN SUMBER MAKANAN BERPROTEIN TINGGI DI SUMATERA BARAT Sari, Santi Amelia; Putri, Restika; Suparmin, Suparmin; Astuti, Widya
Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

West Sumatra is an area that still has a high poverty rate is as much as 407,470 people or 8.14% of the total population. One of the effect of this situation is approximately 0.9% of West Sumatra children still suffer from malnutrition due to lack of nutrition, especially protein. By extracting the rice bran, will be acquired proteins that can be used to ensure adequate intake of proteins which have not fulfilled. It’s caused by soybean price instability which has been used as a source of protein for most of the population of West Sumatra. By varying the alkaline solution, pH and extraction time will be obtained optimum conditions to obtain the highest protein concentrate that can be used as an alternative protein source. For the determination of protein content contained in each sample was used Kjeldahl method. Having done this research, was obtained the optimum conditions is KOH solution with extraction time was 3 hours and pH 10. Based on the results of ANOVA test shows that the extraction time and extraction pH have significant effect on the yield of concentrate protein. But, extraction solution factor didn’t have significant effect.Keywords: Extraction, Rice bran, Enrichment, Sources of food, High protein

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